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高速公路沥青路面早期损坏原因及试验检测

时代汽车 2024年第15期 22-24页

作者：唐杰刘金刚南通路桥工程有限公司江苏南通226000

本文研究了高速公路沥青路面早期损坏原因及试验检测方法。针对早期损坏的主要原因,提出了针对性的试验检测方法,如钻芯取样、动态探测和红外成像技术。通过深入分析损坏类型、识别与评估措施,以及预防与维护措施的探讨,旨在提高对沥青... 详细信息

本文研究了高速公路沥青路面早期损坏原因及试验检测方法。针对早期损坏的主要原因,提出了针对性的试验检测方法,如钻芯取样、动态探测和红外成像技术。通过深入分析损坏类型、识别与评估措施,以及预防与维护措施的探讨,旨在提高对沥青路面损坏的认识,促进早期问题发现和有效处理,确保道路质量和行车安全。

关键词：高速公路沥青路面早期损坏试验检测

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装配式建筑套筒用灌浆料的配制与性能研究

广东建材 2024年第9期40卷 89-93页

作者：周小华方金刚广州城建职业学院

灌浆料直接影响套筒灌浆接头的性能,为制备力学性能好、成本低、绿色环保的套筒用灌浆料,本文在对硅酸盐水泥和硫铝酸盐水泥进行复配的基础上,使用机制砂、粉煤灰、矿粉等材料,以流动性和抗压强度为指标,设计了正交试验。结果表明:水胶... 详细信息

灌浆料直接影响套筒灌浆接头的性能,为制备力学性能好、成本低、绿色环保的套筒用灌浆料,本文在对硅酸盐水泥和硫铝酸盐水泥进行复配的基础上,使用机制砂、粉煤灰、矿粉等材料,以流动性和抗压强度为指标,设计了正交试验。结果表明:水胶比是影响灌浆料流动性和抗压强度的关键因素;套筒灌浆料最优配比为:水胶比0.23、胶砂比1.0:0.8、粉煤灰掺量10%、矿粉掺量4%、机制砂取代量25%,其中胶凝材料中硫铝酸盐水泥的掺量为20%。对灌浆料进行试配:各项性能均优于JG/T 408-2019的性能指标,用于实际工程中,灌浆接头的力学性能符合JGJ 355-2015要求。

关键词：灌浆料制备套筒连接配合比优化正交试验

计及互感器融合偏差的变电站站用电剩余电流监测系统研究

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电工电能新技术 2024年第8期43卷 69-77页

作者：田金虎汪金刚徐郁潘子豪杨皓博国网重庆市电力公司超高压分公司重庆400039 输变电装备技术全国重点实验室(重庆大学) 重庆400044

稳定的站用电源系统是变电站生产设备可靠工作之本,一旦站用电系统出现问题将直接或间接地影响变电站安全。目前变电站站用电绝缘监测主要通过对变电站电源系统剩余电流实时监测实现。然而剩余电流监测方法主要面向多电流互感器融合测... 详细信息

稳定的站用电源系统是变电站生产设备可靠工作之本,一旦站用电系统出现问题将直接或间接地影响变电站安全。目前变电站站用电绝缘监测主要通过对变电站电源系统剩余电流实时监测实现。然而剩余电流监测方法主要面向多电流互感器融合测量场合,现有的测量系统未考虑融合过程中互感器偏差影响,致使误报警状况频出。有鉴于此,本文提出了一套计及互感器融合偏差的变电站站用电剩余电流监测系统。该系统同步采集并实时合成多通道电流互感器剩余电流数据,并利用自回归差分移动平均模型(ARIMA)对剩余电流进行时序建模与异常检测,再使用小波阈值去噪算法对修复后的剩余电流序列降噪,以实现剩余电流的高效、精准监测。为验证所提出系统的有效性,在变电站进行现场试验。结果表明,该系统能够成功识别并修复剩余电流异常值数据且去噪效果显著。修复数据最大绝对误差仅5.9 mA,与0.5S级互感器测量数据相比,去噪后数据平均绝对百分比误差与均方根误差分别降低了0.024与1.222。

关键词：剩余电流监测系统互感器融合偏差 ARIMA模型小波阈值去噪

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河南农村电商创业优化路径探究

广东蚕业 2024年第7期58卷 154-156页

作者：卢金刚魏千许昌陶瓷职业学院河南许昌461100

随着乡村振兴战略不断推进,更多人加入农村电商的创业队伍,在政府的扶持下,河南省农村电商发展取得了明显成效。文章采用问卷调查法与访谈法,以河南省农村电商创业者为研究对象,分析了河南省农村电商创业存在的主要问题,从基础设施建设... 详细信息

随着乡村振兴战略不断推进,更多人加入农村电商的创业队伍,在政府的扶持下,河南省农村电商发展取得了明显成效。文章采用问卷调查法与访谈法,以河南省农村电商创业者为研究对象,分析了河南省农村电商创业存在的主要问题,从基础设施建设、创业教育与融资渠道等维度提出了优化路径,以期提高河南省农村电商发展质量。

关键词：乡村振兴河南省农村电商创业优化路径

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基于弥散颗粒燃料的先进核反应堆大规模并行模拟与优化

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计算机研究与发展 2024年第4期61卷 973-982页

作者：李睿涵侯叶凡李玉辉刘召远张海红梁金刚清华大学核能与新能源技术研究院北京100084 齐鲁工业大学(山东省科学院) 济南250353

颗粒燃料是将核燃料制成颗粒并弥散在基体中的一种新型燃料构型,广泛应用于高温气冷堆、空间堆、氟盐冷却高温堆等先进堆型中.以高温气冷堆和空间堆为例,基于开源蒙特卡罗程序OpenMC研究了适用于颗粒燃料临界计算的虚拟网格模拟加速方法... 详细信息

颗粒燃料是将核燃料制成颗粒并弥散在基体中的一种新型燃料构型,广泛应用于高温气冷堆、空间堆、氟盐冷却高温堆等先进堆型中.以高温气冷堆和空间堆为例,基于开源蒙特卡罗程序OpenMC研究了适用于颗粒燃料临界计算的虚拟网格模拟加速方法,并在山河超算平台开展了超10万核心的大规模并行测试.结果表明,高温气冷堆模型的有效增殖因数计算结果与石岛湾核电站实验数据符合较好,验证了程序及模型的准确性.在性能方面,虚拟网格方法与OpenMC此前的真实网格方法相比,在存储空间和计算速度上均有明显提升,高温气冷堆虚拟网格模型的内存和耗时分别为真实网格模型的0.2%和82%;此外,由于虚拟网格方法简化了模型几何,其间接实现了更好的负载均衡,使得程序拥有了更高的并行效率.对于强可扩展性,在10752核规模的测试中,虚拟网格的并行效率为83.4%,而真实网格为63.6%;对于弱可扩展性,虚拟网格模型在131600核并行效率为83.1%,而真实网格为66.1%.

关键词：核反应堆弥散颗粒燃料蒙特卡罗大规模并行网格加速

Reconciled estimation of Antarctic ice sheet mass balance and contribution to global sea level change from 1996 to 2021

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Science China Earth Sciences 2024年

作者： Rongxing LI Guojun LI Gang HAI Huan XIE Yuan CheNG Wei CheN Xiangbin CUI Minghu DING Chunchun GAO Tong HAO Changqing KE Chuanjin LI Jin LI Yan LIU Jiangjun RAN Jiawen REN Qiang SheN Yunzhong SheN Hongling SHI Songyun WANG Zemin WANG jingang ZHAN Baojun ZHANG Min ZHONG Chunxia ZHOU State Key Laboratory of Remote Sensing Science Faculty of Geographical Science Beijing Normal University Department of Earth and Space Sciences Southern University of Science and Technology State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and Resources Chinese Academy of Sciences State Key Laboratory of Geodesy and Earth's Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences Center for Space Research University of Texas at Austin Chinese Antarctic Center of Surveying and Mapping Wuhan University School of Geospatial Engineering and Science Sun Yat-sen University Center for Spatial Information Science and Sustainable Development Applications Tongji University College of Surveying and Geo-informatics Tongji University Institute for the Conservation of Cultural heritage School of Cultural Heritage and Information Management Shanghai University College of Resource Environment and Tourism Hubei University of Arts and Science Polar Research Institute of China State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences College of Geodesy and Geomatics Shandong University of Science and Technology School of Geography and Ocean Science Nanjing University Shanghai Astronomical Observatory Chinese Academy of Sciences

The Antarctic Ice Sheet（AIS） has been losing ice mass and contributing to global sea level rise（GSLR）. Given its mass that is enough to cause ～58 m of GSLR, accurate estimation of mass balance trend is critical for AIS mass loss monitoring and sea level rise forecasting. here, we present an improved approach to reconciled solutions of mass balance in AIS and its regions from multiple contributing solutions using the input-out, altimetric, and gravimetric methods. In comparison to previous methods, such as IMBIE 2018, this approach utilizes an adaptive data aggregation window to handle the heterogeneity of the contributing solutions, including the number of solutions, temporal distributions, uncertainties, and estimation techniques. We improved the regression-based method by using a two-step procedure that establishes ensembled solutions within each method（input-output, altimetry, or gravimetry） and then estimates the method-independent reconciled solutions. For the first time, 16contributing solutions from 8 Chinese institutions are used to estimate the reconciled mass balance of AIS and its regions from1996 to 2021. Our results show that AIS has lost a total ice mass of ～3213±253 Gt during the period, an equivalent of～8.9±0.7 mm of GSLR. There is a sustained mass loss acceleration since 2006, from 88.1±3.6 Gt yr-1during 1996–2005 to 130.7±8.4 Gt yr-1during 2006–2013 and further to 157.0±9.0 Gt yr-1during 2014–2021. The mass loss signal in the West Antarctica and Antarctic Peninsula is dominant and clearly presented in the reconciled estimation and contributing solutions, regardless of estimation methods used and fluctuation of surface mass balance. Uncertainty and challenges remain in mass balance estimation in East Antarctica. This reconciled estimation approach can be extended and applied for improved mass balance estimation in the Greenland Ice Sheet and mountain glacier regions.

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肉桂酸对早期心肌肥大的干预作用及促进脂肪酸转运的机制研究

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中华中医药杂志 2024年第5期39卷 2181-2187页

作者：崔艺萌王玉珏崔金刚陈瑜张腾上海中医药大学附属岳阳中西医结合医院上海200437 上海市中医药研究院中西医结合临床研究所上海200437

目的:旨在明确桂枝的主要活性成分单体肉桂酸(CA)是否对主动脉缩窄(TAC)和苯肾上腺素(PE)诱导心肌肥大具有干预作用,并基于生物信息学分析进一步探讨CA发挥作用的相关分子机制。方法:体内实验:采用TAC手术构建小鼠心肌肥大模型,测算小... 详细信息

目的:旨在明确桂枝的主要活性成分单体肉桂酸(CA)是否对主动脉缩窄(TAC)和苯肾上腺素(PE)诱导心肌肥大具有干预作用,并基于生物信息学分析进一步探讨CA发挥作用的相关分子机制。方法:体内实验:采用TAC手术构建小鼠心肌肥大模型,测算小鼠心脏质量指数,免疫荧光标记小麦胚芽凝集素(WGA)和心肌肥大标志物心房利钠肽(ANP)评估心肌肥大改变。he、Masson’s Trichrome染色观察心脏病理损伤情况。体外实验:采用PE诱导原代心肌细胞(NRCMs)肥大模型评估CA是否具有直接的抗心肌肥大作用,罗丹明-鬼笔环肽和ANP染色评估心肌细胞肥大改变。RNA-seq分析差异基因。BODIPYTM 500/510染色评估脂肪酸转运能力。实时荧光定量PCR(qPCR)和蛋白质印迹(WB)法验证差异基因的表达。结果:体内实验:CA显著抑制TAC诱导的小鼠左心室重塑(P<0.05)。体外实验:CA显著抑制PE诱导的NRCMs肥大(P<0.05)。RNA-seq数据表明,脂肪酸转运途径及相关分子表达水平在PE组显著下调(P<0.05)。BODIPYTM 500/510染色结果提示CA显著抑制PE诱导的NRCMs脂肪酸转运能力降低(P<0.05)。qPCR和WB结果进一步验证CA显著抑制PE诱导NRCMs肉毒碱棕榈酰基转移酶1A(CPT1A)表达水平的降低(P<0.05)。结论:CA通过抑制早期心肌细胞肥大有效改善TAC诱导的左心室重塑,其机制可能部分基于上调CPT1A促进心肌细胞脂肪酸转运。

关键词：肉桂酸心肌肥大心力衰竭左心室重塑脂肪酸转运肉毒碱棕榈酰基转移酶1A

The Expression and Characterization of a Bifunctional Protein in *** for Autologous Erythrocyte Agglutination Test

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Cellular & Molecular Immunology 2008年第4期5卷 299-306页

作者： Changli Shao jingang Zhang Institute of Transfusion Medicine Academy of Military Medical SciencesBeijing 100850 China Biochemistry Department Chinese PLA General Hospital Beijing 100853China

H antigen, the precursor of A and B antigens, belongs to Hh blood system in which it is the only antigen. H antigen distributes on all the human RBC surface except for Bombay phenotype and the copy number of H antigen on the surface of an adult RBC is approximately 1.7 × 10^6. These characteristics made H antigen the potential target molecule for the immunoassay and immunotherapy. A monoclonal antibody 2E8 against H antigen on the surface of erythrocyte had been prepared in previous work. Based on this antibody, the variable region genes of heavy and light chains （Vu and VL） from 2E8 had been cloned by 5＇ RACE. The two variable region genes were spliced by overlap extension and assembled ScFv （Vu-linker-VL） gene encoding the anti-H antigen named ScFv2Es. According to the prediction of the three-dimension structure of ScFv2Es and Cul fragment from 2E8 and HIV-1 gp41 antigen peptide, we further constructed the ScFv2Es-Cul-gp41 fusion molecule. The recombinant ScFv2Es-Cul-gp41 gene was cloned into pET-his vector and expressed in BL21（DE3）plysS cells. The fusion protein was purified from the inclusion bodies. In a series of subsequent analyses, this fusion protein showed identical antigen binding site and activity with the parent antibody. Meanwhile, in mimic test, as the main ingredient of reagent for autologous erythrocyte agglutination test, the bifunctional protein could agglutinate the RBCs in the presence of HIV-1 gp41 antibodies using sera from HIV-infected individuals. Cellular ＆ Molecular Immunology. 2008;5（4）：299-306.

关键词： agglutination bifunctional protein

Surface modification of Ti-6Al-4V alloy by cathode assiting discharge setup and conventional plasma nitriding methods

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Science China(Technological Sciences) 2013年第8期56卷 1858-1864页

作者： TANG jingang LIU DaoXin TANG ChangBin ZHANG XiaoHua Corrosion & Protection Research Institute Northwestern Polytechnical University Xi'an University of Architecture and Technology

In order to improve the wear resistance of titanium alloys,the potential of the plasma nitriding process with a cathode assiting discharge setup was ***6Al4V alloy was nitrided by the cathode assiting discharge nitriding(CAN) and conventional DC plasma nitriding(CPN) methods,*** micro-topography,phase composition and cross-sectional microhardness distribution of two nitriding layers were studied *** sliding wear resistance of the nitriding layers was examined by a ball-on-disk test against Si3N4 *** results indicated that the surface roughness Ra of the CAN layer was about 1 order less than that of the CPN *** addition,the CAN surfaces possessed significantly greater wear resistance than the CPN layer at higher loads,and increased the wear resistance of Ti6Al4V alloy by about 2 orders due to the higher loading bearing ability,higher rate of TiN phase,greater surface microhardness and bigger microhardness improving *** is because the double glow discharge effect in CAN strengthened the density of the active nitrogen atoms and the nitriding ***,the ion bombardment effect on the surface of the nitriding titanium alloy was reduced obviously.

关键词： nitriding Ti6Al4V cathode assiting discharge wear

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