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Molecular Determinants Responsible for the Subcellular Localization of HSV-1 UL4 Protein

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Virologica Sinica 2011年第5期26卷 347-356页

作者： wei-wei Pan jing Long Jun-ji Xing Chun-fu zheng Molecular Virology and Viral Immunology Research Group State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan 430071 China

The function of the herpes simplex virus type 1 （HSV-1） UL4 protein is still elusive. Our objective is to investigate the subcellular transport mechanism of the UL4 protein. In this study, fluorescence microscopy was employed to investigate the subcellular localization of UL4 and characterize the transport mechanism in living cells. By constructing a series of deletion mutants fused with enhanced yellow fluorescent protein （EYFP）, the nuclear export signals （NES） of UL4 were for the first time mapped to amino acid residues 178 to 186. In addition, the N-terminal 19 amino acids are identified to be required for the granule-like cytoplasmic pattem of UL4. Furthermore, the UL4 protein was demonstrated to be exported to the cytoplasm through the NES in a chromosomal region maintenance 1 （CRM1）-dependent manner involving RanGTP hydrolysis

关键词： Herpes simplex virus type 1 (HSV-1) UL4 Subcellular localization Nuclear export signal (NES) Chromosomal region maintenance 1 (CRM 1)

Thermoelastic topology optimization for structures with temperature-dependent material properties

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Science China(Technological Sciences) 2023年第12期66卷 3488-3503页

作者： zheng jing RONG XuanPei JIANG Chao State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body School of Mechanical and Vehicle EngineeringHunan UniversityChangsha 410082China

A thermoelastic topology optimization is proposed for structures with temperature-dependent material *** from the common assumption of constant material properties in traditional thermoelastic topology optimization,the temperaturedependent material properties related to mechanical and thermal fields are taken into *** non-uniform temperature distribution of the structure is a design dependent field that may vary during the optimization,and the nonlinear heat transfer analysis is considered according to the large temperature *** on these,a thermoelastic topology optimization model considering temperature-dependent material properties is *** sensitivities with respect to the design variables are derived and the Method of Moving Asymptotes(MMA)algorithm is used to update the topological design variables.A cooperation platform based on MATLAB and ABAQUS is developed for the proposed thermoelastic topology optimization method to deal with problems with arbitrary domains for the design of complex engineering *** typical numerical examples are given to illustrate the effectiveness of the proposed method and show the important influence of the temperaturedependent material properties.

关键词： thermoelastic topology optimization nonlinear heat transfer temperature-dependent material properties

Daily Intra Day Collaborative Rolling Optimization Strategy for Solar Energy Storage Power Stations Participating in Multiple Application Scenarios

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Dianwang Jishu/Power System Technology 2025年第1期49卷 198-208页

作者： Liu, Zifa Li, Kunyang zheng, Siqi School of Electrical and Electronic Engineering North China Electric Power University Changping District Beijing 102206 China

The joint operation of photovoltaic power stations and energy storage systems can reduce the uncertainty of power output from the power supply side and improve the stability of the power grid. The current application scenarios for solar energy storage power stations are relatively single, making it difficult to simultaneously consider primary and secondary frequency regulation and joint electricity sales. In response to this issue, this paper proposes a multi-scenario compatible day-ahead rolling optimization operation strategy that considers the electricity market and primary and secondary frequency regulation services. Firstly, the characteristics of primary and secondary frequency modulation signals will be analyzed, and a collaborative optimization strategy framework for hybrid energy storage in photovoltaic power plants will be proposed under multi-application scenario scheduling resolution. Then, to maximize the joint revenue of the station, a daily optimization model is established that considers the secondary frequency regulation capacity of energy storage. In the intraday stage, the actual output priority of each scenario is considered, and a rolling optimization solution is obtained to obtain the operation plan of the energy storage system. Using actual data from a photovoltaic power station in Daqing, Heilongjiang Province, simulation verification was conducted, and sensitivity analysis was conducted on the model. The example shows that the optimization strategy proposed in this paper can unleash the scheduling potential of different energy storage resources, effectively improve the accuracy of power station reporting and frequency regulation ability. © 2025 Power System Technology Press. All rights reserved.

关键词： Sensitivity analysis

Adaptive path planning for unmanned aerial vehicles based on bi-level programming and variable planning time interval

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Chinese Journal of Aeronautics 2013年第3期26卷 646-660页

作者： Liu wei zheng zheng Cai Kaiyuan School of Automation Science and Electrical Engineering Beihang University Science and Technology on Aircraft Control Laboratory High-Tech Institute of Xi'an

This paper presents an adaptive path planner for unmanned aerial vehicles （UAVs） to adapt a real-time path search procedure to variations and fluctuations of UAVs’ relevant performances, with respect to sensory capability, maneuverability, and flight velocity limit. On the basis of a novel adaptability-involved problem statement, bi-level programming （BLP） and variable planning step techniques are introduced to model the necessary path planning components and then an adaptive path planner is developed for the purpose of adaptation and optimization. Additionally, both probabilistic-risk-based obstacle avoidance and performance limits are described as path search constraints to guarantee path safety and navigability. A discrete-search-based path planning solution, embedded with four optimization strategies, is especially designed for the planner to efficiently generate optimal flight paths in complex operational spaces, within which different surface-to-air missiles （SAMs） are deployed. Simulation results in challenging and stochastic scenarios firstly demonstrate the effectiveness and efficiency of the proposed planner, and then verify its great adaptability and relative stability when planning optimal paths for a UAV with changing or fluctuating performances.

关键词： Adaptive Bi-level programming Motion planning Unmanned aerial vehicles Variable time interval

Convergence analysis for delay Volterra integral equation

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Applied Mathematics(A Journal of Chinese Universities) 2022年第2期37卷 306-316页

作者： zheng wei-shan College of Mathematics and Statistics Hanshan Normal UniversityChaozhou 521041China

In this article we use Chebyshev spectral collocation method to deal with the Volterra integral equation which has two kinds of delay items. We use linear transformation to make the interval into a fixed interval [-1, 1]. Then we use the Gauss quadrature formula to approximate the solution. With the help of lemmas, we get the result that the numerical error decay exponentially in the infinity norm and the Chebyshev weighted Hilbert space norm. Some numerical experiments are given to confirm our theoretical prediction.

关键词： Chebyshev spectral collocation method delay Gauss quadrature formula convergence analysis

Preparation of Aryloxy-aluminoxanes and Their Use as Activators in the Bis(imino)pyridyl Iron-catalyzed Oligomerization of Ethylene

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Chinese Journal of Polymer Science 2018年第11期36卷 1207-1207,1208-1216页

作者： wei Zhang Bin-Bo Jiang Jian Ye Zu-wei Liao zheng-Liang Huang jing-Dai Wang Yong-Rong Yang Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture Technology State Key Laboratory of Chemical Engineering College of Chemical and Biological Engineering Zhejiang University

In this study, a series of aryloxy-aluminoxanes originated directly from the hydrolysis of reaction products of A1Me3 and phenols were synthesized, which could serve as effective polymer-retarding activators for the iron-catalyzed ethylene oligomerization. The molar ratios of [PhOH]/[AlMe3] and [H2O]/[Al] during the preparation were explored and their impacts on the oligomerization activity and product distribution were discussed. To obtain the effective activators with good polymer-retarding effect and relatively high activity, the optimized conditions were proposed to be [PhOH]/[AlMe3] = 0.5 and [H2O]/[Al] = 0.7. Various aluminoxanes with different [-OH] sources confirmed the importance of using phenols in preparing the effective polymer-retarding activators. By utilizing these aryloxy-aluminoxanes, the mass fraction of polymers in the total products could be reduced to lower than 1.0 wt%, which is much lower than that of the MAO-activated systems （〉 30 wt%）. This is a potential benefit for the industrial application of the iron-catalyzed oligomerization process.

关键词： Ethylene oligomerization Bis(imino)pyridyl iron catalysts Aryloxy-aluminoxanes Phenols Trimethylaluminum hydrolysis

Highly reliable bipolar resistive switching in sol-gel derived lanthanum-doped PbTiO_3 thin film: Coupling with ferroelectricity?

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Acta Mechanica Sinica 2014年第4期30卷 526-532页

作者： Ying Wang wei-Jin Chen Xiao-Yue Zhang Wen-jing Ma Biao Wang Yue zheng State Key Laboratory of Optoelectronic Materials and Technologies School of Physics and EngineeringSun Yat-sen University Micro & Nano Physics and Mechanics Research Laboratory School of Physics and EngineeringSun Yat-sen University

Nanoscale PbxLa1-,Ti1-x/4O3 （PLT） thin film has been fabricated on Pt／Ti／SiO2／Si substrates by chemical solution deposition （CSD） method. Ferroelectricity of the fresh-made PLT thin film has been clearly detected through piezoelectric force microscopy （PFM） by writing reversible ferroelectric domains. However, PLT thin film also shows off-standard ferroelectric hysteresis loops highly dependent on frequency, indicating large amount of mobile space charges in the film. Subsequent current-voltage （C-V） studies show that sandwich-like Pt／PLT／Pt structure exhibits notable bipolar resistive switching （BRS） characteristics with high stability （〉 103 switching cycles）. It is found that the C-V curves of both high- and low-resistance states have the feature of space-charge-limited current （SCLC） conduction, indicating important roles of defects in the conduction. X-ray photoelectron spectroscopy measurement further verifies that oxygen vacancies based conductive filament mechanism is likely responsible for the observed RS effect. Our demonstration of stable RS effect in the PLT thin film and its possible coupling with ferroelectricity is promising in device development and applications, such as development of ferroelectric-tunable RS memories.

关键词： Ferroelectricity Resistive switching - Stability -Oxygen vacancy

Reconfigurable metasurfaces that enable light polarization control by light

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Light(Science & Applications) 2016年第1期5卷 74-78页

作者： Meng-Xin Ren wei Wu wei Cai Biao Pi Xin-zheng Zhang jing-Jun Xu The Key Laboratory of Weak-Light Nonlinear Photonics Ministry of EducationSchool of Physics and TEDA Institute of Applied PhysicsNankai UniversityTianjin 300071China The 2011 Project Collaborative Innovation Center for Biological Therapy Nankai UniversityTianjin 300071China

Plasmonic metasurfaces have recently attracted much attention because of their novel characteristics with respect to light polarization and wave front control on deep-subwavelength *** development of metasurfaces with reconfigurable optical responses is opening new opportunities in high-capacity communications,real-time holograms and adaptive *** tunable devices have been developed in the mid-infrared spectral range and operated in light intensity modulation *** we present a novel optically reconfigurable hybrid metasurface that enables polarization tuning at optical *** functionality of tuning is realized by switching the coupling conditions between the plasmonic modes and the binary isomeric states of an ethyl red switching layer upon light *** achieved more than 20°nonlinear changes in the transmitted polarization azimuth using just 4 mW of switching light *** design schemes and principles could be easily applied to dynamically adjust the functionalities of other metasurfaces.

关键词： azo ethyl red metasurfaces nonlinear polarization modulation photoisomerization reconfigurable

Changes of moisture distribution and migration in fresh ear corn during storage

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Journal of Integrative Agriculture 2019年第11期18卷 2644-2651页

作者： WANG Hao LIU jing-sheng MIN wei-hong zheng Ming-zhu LI Hao College of Food Science and Engineering/The National Engineering Laboratory on Wheat and Corn Further Processing Jilin Agricultural University

Understanding of moisture changes in fresh ear corn(Zea mays L.)during storage is imperative for maintaining fresh corn *** changes of moisture distribution and migration in fresh ear corn during storage were investigated using low-field nuclear magnetic resonance(NMR)and magnetic resonance imaging(MRI).Water loss was greater than water migration in fresh ear corn within the first hour of storage;thereafter,water loss was weaker than water *** the extension of storage time,the signal intensity of MRI in different parts of sliced fresh corn with cob showed a downward trend,and the rate of signal intensity reduction was higher in the peripheral area than at the central part of sliced fresh corn with *** relative proportion of bound water increased with a concomitant drop in that of free water,when the total water content reduced in fresh ear corn under *** conclusion,NMR and MRI are useful and non-destructive tools for real-time monitoring of moisture distribution,migration,and loss in fresh ear corn during storage to assess its *** results can be used for future design of the preserving and processing conditions for fresh ear corn.

关键词： fresh ear corn NMR MRI moisture distribution moisture migration