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Robotic-assisted resection of ovarian tumors in children: A case report and review of literature

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World Journal of Clinical Cases 2019年第17期7卷 2542-2548页

作者： Xiao-Xiao Xie Ning wang Zi-Hao wang Yue-Yue Zhu jing-ru wang Xian-Qiang wang Department of Obstetrics and Gynecology PLA General HospitalBeijing 100853China Department of Pediatrics PLA General HospitalBeijing 100853China The Fourth Military Medical University Xi’an 710032Shanxi ProvinceChina Southern Medical University Guangzhou 510515Guangdong ProvinceChina

BACKGROUND Ovarian tumors are common gynecological diseases in children, and the most commonly seen ovarian tumors are germ cell tumors. Robotic surgery is the new access for children ovarian *** SUMMARY From June to October 2017, 4 children with ovarian tumors were admitted and treated in the Department of Pediatric Surgery of People’s Liberation Army General Hospital. The mean age, height, and weight of these patients were 7.5(1-13) years old, 123.75(71-164) cm, and 36.8(8.5-69.5) kg, respectively. Roboticassisted resection of ovarian tumors was performed for all 4 patients. The 3-port approach was used for robotic manipulation. The surgical procedures were as follows. After creation of the pneumoperitoneum, the robotic scope was placed to explore and find the left ovarian tumor. The trocars for robotic arms 1 and 2 were placed at the sites to the lower right and left of the port of the scope. The tumor capsule in the fallopian tube was incised, and the tumor was completely stripped by an electric hook along the junction of the tumor and the capsule. The resected tumor was completely removed using an endobag. The average docking time of the robotic system was 18.5 min, the average operative time was 120 min, and the average blood loss was 20 m L. No drainage tube was placed except in one patient with a mucinous tumor of the ovary. No fever, pelvic fluid, or intestinal obstruction was reported after surgery. No antibiotics were used during the perioperative period, and the average length of hospital stay after surgery was 3 *** Robotic-assisted resection of ovarian tumors is a simple, safe, and effective surgical procedure for selected patients.

关键词： Children Robotic surgery Ovarian tumor resection Case report

Intermittent sliding-lock-knot suture for limbal conjunctival autograft fixation in pterygium surgery:a technique note

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 838-844页

作者： Ling Zhang run-Hua Lyu jing-ru wang Wen-Jian Shi Feng Zheng Ying-Ying Gao Department of Ophthalmology the Second Affiliated HospitalFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Neurosurgery the Second Affiliated HospitalFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

AIM:To report a technique used with intermittent slidinglock-knot(ISLK)fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent(RI)***:Consecutive patients with primary pterygium who had undergone pterygium excision combined with limbal conjunctival autograft transplantation between March 2021 and March 2022 at our institute were retrospectively *** outcome measures were mean duration of surgery and suture removal,degree of conjunctival hyperemia on postoperative day 1,pain score at suture removal,postoperative symptoms at 6mo,including conjunctival hyperemia,foreign body sensation,and graft ***:Ninety-eight patients underwent monocular surgery and were divided into ISLK(51 eyes)and RI(47 eyes)groups according to the type of conjunctiva autograft fixation method *** was no significant difference in mean duration of surgery between the two groups(18.59±2.39min vs 18.15±2.20min,P=0.417);however,compared to the RI group,shorter suture removal times were observed in the ISLK group[0.58min(0.42-0.87)vs 3.00min(2.21-4.15),P<0.001].The degree of conjunctival hyperemia on postoperative day 1 was milder in the ISLK group(P<0.001).Pain scores at suture removal were lower in the ISLK group than in RI group[1(0-3)vs 2(1-4),P<0.001].Postoperative symptoms at 6mo were comparable between the groups(P=0.487),with no ***:ISLK is an innovative method for limbal conjunctival autograft fixation after pterygium *** to RI fixation,ISLK facilitates suture removal and reduces discomfort,with comparable surgery duration and less conjunctival hyperemia.

关键词： intermittent sliding-lock-knot fixation pterygium suture removal

Screening of pathogenic genes in Chinese patients with arrhythmogenic right ventricular cardiomyopathy

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Chinese Medical Journal 2013年第22期126卷 4238-4241页

作者： BAO jing-ru wang Ji-zheng YAO Yan wang Yi-lu FAN Xiao-han SUN Kai ZHANG Shu HUI ru-tai SONG Lei Chinese Acad Med Sci Peking Union Med Coll State Key Lab Cardiovasc Dis Natl Ctr Cardiovasc DisFuwai HospArrhythmia Ctr Beijing 100037 Peoples R China Chinese Acad Med Sci Peking Union Med Coll State Key Lab Cardiovasc Dis Natl Ctr Cardiovasc DisFuwai HospClin Ep Lab Beijing 100037 Peoples R China Chinese Acad Med Sci Peking Union Med Coll State Key Lab Cardiovasc DisFuwai Hosp Sino German Lab Mol MedNatl Ctr Cardiovasc Dis Beijing 100037 Peoples R China Chinese Acad Med Sci Peking Union Med Coll State Key Lab Cardiovasc Dis Natl Ctr Cardiovasc DisHypertens CtrFuwai Hosp Beijing 100037 Peoples R China

Background Arrhythmogenic right ventricular cardiomyopathy （ARVC） is a heritable cardiac disease predominantly caused by mutations in desmosomal protein genes. Previous genetic analyses of the Chinese ARVC population are limited to small size and restriction to a single gene. This study was aimed to investigate the genotype in a large series of Chinese patients with ARVC through comprehensively screening nine ARVC-causing genes. Methods A total of 100 unrelated ARVC patients and 300 age, gender and ethnicity matched healthy controls were genetically tested with multiplexing targeted resequencing for nine previously reported ARVC-causing genes, including plakophilin-2, desmoplakin, desmoglein-2, desmocollin-2, plakoglobin, transforming growth factor beta-3, transmembrane protein 43, desmin and Lamin A/C. Results Fifty-nine mutations were identified in 64% of the patients, among which, 93% were located in desmosomal protein genes. Plakophilin-2 mutations accounted for 54% of the total and 58% of the desmosomal mutations, with a truncating mutation type making up about 2/3 of the plakophilin-2 mutations. Only four mutations were found in nondesmosomal genes; two in transmembrane protein 43 and two in transforming growth factor beta-3. Two of them （one of each gene） appeared as single missense mutations. No mutation was identified in desmin or Lamin A/C. Multiple mutations were found in 23% of the patients, with plakophilin-2 being found in 57% of the multi-mutation carriers. Conclusions Plakophilin-2 was the most common gene mutation that was identified in Chinese ARVC patients. Nondesmosomal genes should be added to desmosomal protein genes when performing molecular genetic screening in patients with suspected ARVC.

关键词： arrhythmogenic right ventricular cardiomyopathy genetic testing, plakophilin-2

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氯化钙/膨胀石墨混合吸附剂的吸附特性

上海交通大学学报 2009年第2期43卷 271-274页

作者：王凯吴静怡王如竹上海交通大学制冷与低温研究所上海200240

将氯化钙与膨胀石墨相混合,利用膨胀石墨丰富的微孔来强化氯化钙的传质,可解决化学吸附剂吸附过程中由于结块现象而导致的性能衰减现象.氯化钙/膨胀石墨固化后可以提高吸附剂的体积制冷量,从而提高吸附制冷系统的制冷性能.对4种不同组... 详细信息

将氯化钙与膨胀石墨相混合,利用膨胀石墨丰富的微孔来强化氯化钙的传质,可解决化学吸附剂吸附过程中由于结块现象而导致的性能衰减现象.氯化钙/膨胀石墨固化后可以提高吸附剂的体积制冷量,从而提高吸附制冷系统的制冷性能.对4种不同组分的氯化钙/膨胀石墨混合吸附剂的吸附性能进行测试,当蒸发温度为-10°C时,固化混合吸附剂的体积制冷量比氯化钙高45%.

关键词：吸附制冷氯化钙膨胀石墨

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong jing-jing Hu Yan Yu Xiao-Li Li Xiao-Ting Sun Li-Ting wang Xia Wu Ling-Jie Zhu Xiao-Jia Yang Qian-ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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认知功能障碍患者病前智力评价

中国现代神经疾病杂志 2016年第9期16卷 636-639页

作者：邹扬陈美蓉任汝静王刚上海交通大学医学院附属瑞金医院神经科上海交通大学医学院神经病学研究所200025 上海市普陀区人民医院神经内科 200060

神经心理学测验是痴呆和认知功能障碍诊断的重要依据。不同个体健康状态下基础认知水平不同,故发病后不应采用相同的评价标准来判断神经心理学测验结果。病前智力评价是修正此类误差的有效方法,但临床对该领域的重视程度仍较低,本文对... 详细信息

神经心理学测验是痴呆和认知功能障碍诊断的重要依据。不同个体健康状态下基础认知水平不同,故发病后不应采用相同的评价标准来判断神经心理学测验结果。病前智力评价是修正此类误差的有效方法,但临床对该领域的重视程度仍较低,本文对国内外病前智力评价方法及其在认知功能障碍中的应用进行综述。

关键词：认知障碍智力测验神经心理学测验综述

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渔船用吸附式制冰系统的设计

上海交通大学学报 2003年第7期37卷 1023-1026页

作者：王丽伟吴静怡王如竹许煜雄上海交通大学制冷与低温工程研究所上海200030

采用船用 61 60 A型柴油机为热源 ,设计了一台发动机余热驱动的吸附式制冰系统 .该系统中的吸附工质采用了块状活性炭 ,所设计的系统日产冰 60 0 kg.在吸附床设计中 ,充分考虑了传递通道的影响 ,通过对以往块状活性炭吸附床吸附性能数... 详细信息

采用船用 61 60 A型柴油机为热源 ,设计了一台发动机余热驱动的吸附式制冰系统 .该系统中的吸附工质采用了块状活性炭 ,所设计的系统日产冰 60 0 kg.在吸附床设计中 ,充分考虑了传递通道的影响 ,通过对以往块状活性炭吸附床吸附性能数据的分析 ,完成了吸附床的性能预测 ,结果表明 ,所设计的吸附式制冰系统可以满足要求 .经模拟仿真计算 ,系统的最佳循环时间在 35 min左右 ,相应的单位质量吸附剂的制冷功率为 35

关键词：渔船吸附制冷块状活性炭废热传质通道

Twenty-eight cases of facial acne treated by quick puncture with collateral-pricking cupping

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World Journal of Acupuncture-Moxibustion 2021年第4期31卷 262-265页

作者： jing-ru wang Xiao SUN Xiao-bin ZHANG Wen-juan WEI Cheng-yang JIANG Xin QI Guang-hui YIN Yu-xia MA College of Acupuncture and Massage Shandong University of Traditional Chinese MedicineJinan 250355China College of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine.Jinan 250355China

Objective:To observe the clinical effect of quick puncture with collateral-pricking cupping for facial ***:Twenty-eight patients with acne were treated with pricking acne spot and abdominal region of three toes for bloodletting combined with collateral-pricking cupping on the back,once every 5 days,for3 weeks in succession.A 3-month follow-up was applied to observe the reducing rate and clinical effect of facial skin lesions after ***:Of the 28 cases,9 were cured,12 remarkably effective,5 effective,and 2 *** total effective rate was 92.86%.Conclusion:The effect of pricking acne spot and abdominal region of three toes combined with collateralpricking cupping on the back is good,being worthy of further clinical discussion to promote its application.

关键词： Acne Acne spot Foot three toes Bloodletting Collateral-pricking cupping

波长优选对土壤有机质含量可见光/近红外光谱模型的优化（英文）

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发光学报 2016年第11期37卷 1428-1435页

作者：林志丹汪玉冰王儒敬汪六三鲁翠萍张正勇宋良图刘洋中国科学院合肥智能机械研究所安徽合肥230031 中国科技大学自动化系安徽合肥230026 合肥电子工程学院安徽合肥230037

可见光/近红外光谱模型是土壤属性预测的有效工具。波长优选在光谱建模过程中起着重要作用。文中首先利用从安徽省涡阳县采集的130个砂姜黑土土壤样本获得可见光/近红外光谱,然后利用平滑与多重散射校正联合的光谱预处理方式消除光谱中... 详细信息

可见光/近红外光谱模型是土壤属性预测的有效工具。波长优选在光谱建模过程中起着重要作用。文中首先利用从安徽省涡阳县采集的130个砂姜黑土土壤样本获得可见光/近红外光谱,然后利用平滑与多重散射校正联合的光谱预处理方式消除光谱中的无关变量和冗余信息以提高模型预测结果的相关性,再利用SPXY方法挑选建模集样本,分别利用连续投影算法和遗传算法进行波长优选,最后利用留一法进行交互验证建立有机质含量的主成分回归模型。研究结果显示:连续投影算法和遗传算法都可以有效地减少参与建模的波长数并提高模型的准确度,尤其是遗传算法能够更好地提高土壤有机质含量预测精度,其相关系数、预测均方根误差和相对分析误差分别达到0.931 6,0.214 2和2.319 5。通过合适的特征波长选取,不仅计算量可以大大减少,预测精度也会有效提高。

关键词：可见光/近红外光谱有机质含量光谱预处理样本选择波长优化