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A Multi-UCAV cooperative occupation method based on weapon engagement zones for beyond-visual-range air combat

Defence Technology（防务技术） 2022年第6期18卷 1006-1022页

作者： Wei-hua Li jing-ping shi Yun-yan Wu Yue-ping Wang Yong-xi Lyu School of Automation Northwestern Polytechnical UniversityXi'an710129China Shaanxi Province Key Laboratory of Flight Control and Simulation Technology Xi'an710129China Science and Technology on Aircraft Control Laboratory FACRIXi'an710065China

Recent advances in on-board radar and missile capabilities,combined with individual payload limitations,have led to increased interest in the use of unmanned combat aerial vehicles(UCAVs)for cooperative occupation during beyond-visual-range(BVR)air ***,prior research on occupational decision-making in BVR air combat has mostly been limited to one-on-one *** such,this study presents a practical cooperative occupation decision-making methodology for use with multiple *** weapon engagement zone(WEZ)and combat geometry were first used to develop an advantage function for situational assessment of one-on-one *** encircling advantage function was then designed to represent the cooperation of UCAVs,thereby establishing a cooperative occupation *** corresponding objective function was derived from the one-on-one engagement advantage function and the encircling advantage *** resulting model exhibited similarities to a mixed-integer nonlinear programming(MINLP)*** such,an improved discrete particle swarm optimization(DPSO)algorithm was used to identify a *** occupation process was then converted into a formation switching task as part of the cooperative occupation model.A series of simulations were conducted to verify occupational solutions in varying situations,including two-on-two *** results showed these solutions varied with initial conditions and weighting *** occupation process,based on formation switching,effectively demonstrates the viability of the proposed *** cooperative occupation results could provide a theoretical framework for subsequent research in cooperative BVR air combat.

关键词： Unmanned combat aerial vehicle Cooperative occupation Beyond-visual-range air combat Weapon engagement zone Discrete particle swarm optimization Formation switching

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Bivariate Recursive Equations on Excess-of-loss Reinsurance

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Acta Mathematica Sinica,English Series 2007年第3期23卷 467-478页

作者： jing ping YANG shi Hong CHENG Xiao Qian WANG LMAM School of Mathematical Sciences Peking University Beijing 100871 P. R. China

This paper investigates bivariate recursive equations on excess-of-loss reinsurance. For an insurance portfolio, under the assumptions that the individual claim severity distribution has bounded continuous density and the number of claims belongs to R1 （a, b） family, bivariate recursive equations for the joint distribution of the cedent＇s aggregate claims and the reinsurer＇s aggregate claims are obtained.

关键词： recursive equation R1 (a b) family excess-of-loss reinsurance

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Hardware-in-loop adaptive neural control for a tiltable V-tail morphing aircraft

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Defence Technology（防务技术） 2023年第4期22卷 197-211页

作者： Fu-xiang Qiao jing-ping shi Xiao-bo Qu Yong-xi Lyu School of Automation Northwestern Polytechnical UniversityXi'an710129China Shaanxi Province Key Laboratory of Flight Control and Simulation Technology Xi'an710129China

This paper proposes an adaptive neural control(ANC)method for the coupled nonlinear model of a novel type of embedded surface morphing aircraft which has a tiltable V-tail.A nonlinear model with sixdegrees-of-freedom is *** first-order sliding mode differentiator(FSMD)is applied to the control scheme to avoid the problem of“differential explosion”.Radial basis function neural networks are introduced to estimate the uncertainty and external disturbance of the model,and an ANC controller is proposed based on this design *** stability of the proposed ANC controller is proved using Lyapunov theory,and the tracking error of the closed-loop system is semi-globally uniformly *** effectiveness and robustness of the proposed method are verified by numerical simulations and hardware-in-the-loop(HIL)simulations.

关键词： Morphing aircraft Back-stepping control Adaptive control Neural networks Radial basis function

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Autonomous maneuver decision-making for a UCAV in short-range aerial combat based on an MS-DDQN algorithm

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Defence Technology（防务技术） 2022年第9期18卷 1697-1714页

作者： Yong-feng Li jing-ping shi Wei Jiang Wei-guo Zhang Yong-xi Lyu School of Automation Northwestern Polytechnical UniversityXi'an 710129China Shaanxi Province Key Laboratory of Flight Control and Simulation Technology Xi'an 710129China

To solve the problem of realizing autonomous aerial combat decision-making for unmanned combat aerial vehicles(UCAVs) rapidly and accurately in an uncertain environment, this paper proposes a decision-making method based on an improved deep reinforcement learning(DRL) algorithm: the multistep double deep Q-network(MS-DDQN) algorithm. First, a six-degree-of-freedom UCAV model based on an aircraft control system is established on a simulation platform, and the situation assessment functions of the UCAV and its target are established by considering their angles, altitudes, environments, missile attack performances, and UCAV performance. By controlling the flight path angle, roll angle, and flight velocity, 27 common basic actions are designed. On this basis, aiming to overcome the defects of traditional DRL in terms of training speed and convergence speed, the improved MS-DDQN method is introduced to incorporate the final return value into the previous steps. Finally, the pre-training learning model is used as the starting point for the second learning model to simulate the UCAV aerial combat decision-making process based on the basic training method, which helps to shorten the training time and improve the learning efficiency. The improved DRL algorithm significantly accelerates the training speed and estimates the target value more accurately during training, and it can be applied to aerial combat decision-making.

关键词： Unmanned combat aerial vehicle Aerial combat decision Multi-step double deep Q-network Six-degree-of-freedom Aerial combat maneuver library

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PLASMA RESISTIN LEVELS AND SINGLE-NUCLEOTIDE POLYMORPHISMS IN RESISTIN GENE 5 FLANKING REGION IN PATIENTS WITH STROKE

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Chinese Medical Sciences Journal 2007年第1期22卷 27-32页

作者： Xing-jian Lin Ying-dong Zhang Qing-shan Guan Qing Di jing-ping shi Wei-guo Liu Department of Neurology Nanjing Brain Hospital Nanjing Medical University Nanjing 210029

Objective To analyze the role of resistin in insulin resistance (IR) through investigating the variation of plasma resistin levels and single-nucleotide polymorphisms (SNPs) in resistin gene 5’ flanking region in stroke *** In 103 atherothrombotic cerebral infarction (ACI) patients, 85 lacunar infarction (LI) patients, 70 intracerebral hemorrhage (ICH) patients, and 86 healthy controls, plasma resistin and insulin levels were measured by ELISA , SNPs in resistin gene 5’ flanking region were detected by PCR and direct DNA sequencing. The subjects’ body height and weight, the body mass index, quantitative insulin sensitivity check index (QUICKI), blood pressure, and the concentration of fasting plasma glucose, triglyceride, total cholesterol, creatinine, low-density lipoprotein, and high-density lipoprotein were also determined. Results QUICKI was significantly lower in the ACI and ICH patients (0.316±0.037 and 0.309±0.032, respectively) than that in the controls (0.342±0.043, PG and -537A>C SNPs were not significantly different among the different groups, and those SNPs were not correlated with other clinical and biochemical *** Plasma resistin is associated with stroke by participating in the development of IR. The SNPs in resistin gene 5’ flanking region has no impact on the plasma resistin level.

关键词： resistin insulin resistance single-nucleotide polymorphisms stroke

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Indirubin-3′-monoxime suppresses amyloid-beta-induced apoptosis by inhibiting tau hyperphosphorylation

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Neural Regeneration Research 2016年第6期11卷 988-993页

作者： Shu-gang Zhang Xiao-shan Wang Ying-dong Zhang Qing Di jing-ping shi Min Qian Li-gang Xu Xing-jian Lin Jie Lu Department of Neurology Affiliated Nanjing Brain Hospital Nanjing Medical University Department of Neurology Affiliated Nanjing First Hospital Nanjing Medical University

Indirubin-3′-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer＇s disease. Here, we found that indirubin-3′-monoxime improved the morphology and increased the survival rate of SHSY5 Y cells exposed to amyloid-beta 25–35（Aβ25–35）, and also suppressed apoptosis by reducing tau phosphorylation at Ser199 and Thr205. Furthermore, indirubin-3′-monoxime inhibited phosphorylation of glycogen synthase kinase-3β（GSK-3β）. Our results suggest that indirubin-3′-monoxime reduced Aβ25–35-induced apoptosis by suppressing tau hyperphosphorylation via a GSK-3β-mediated mechanism. Indirubin-3′-monoxime is a promising drug candidate for Alzheimer＇s disease.

关键词： Indirubin-3 amyloid inhibiting suppressed suppressing inhibited neuronal glycogen viability cytometry

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Association between intra-pancreatic fat deposition and diseases of the exocrine pancreas: A narrative review

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World Journal of Gastroenterology 2025年第2期31卷 27-41页

作者： jing Ye Jian-Guo Wang Rong-Qiang Liu Qiao shi Wei-Xing Wang Department of General Surgery Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of Pancreatic Surgery Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

Intrapancreatic fat deposition(IPFD)has garnered increasing attention in recent *** prevalence of IPFD is relatively high and associated with factors such as obesity,age,and ***,the pathophysiological mechanisms underlying IPFD remain unclear,with several potential contributing factors,including oxida-tive stress,alterations in the gut microbiota,and hormonal *** was found to be highly correlated with the occurrence and prognosis of exocrine pan-creatic *** imaging techniques remain the primary diagnostic approach for IPFD,an expanding array of biomarkers and clinical scoring systems have been identified for screening ***,effective treatments for IPFD are not available;however,existing medications,such as glucagon-like peptide-1 receptor agonists,and new therapeutic approaches explored in animal models have shown considerable potential for managing this *** paper reviews the pathogenesis of IPFD,its association with exocrine pancreatic disea-ses,and recent advancements in its diagnosis and treatment,emphasizing the significant clinical relevance of IPFD.

关键词： Intrapancreatic fat deposition Pancreatic steatosis Nonalcoholic fatty pancreas disease Pancreatitis Pancreatic cancer

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魏晋南北朝御史监察制度的变革

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海南广播电视大学学报 2019年第2期20卷 88-93页

作者：蒋世平华东政法大学法律学院上海200042

魏晋南北朝是御史监察制度的重要发展阶段,御史监察制度的系统化、规范化就发生在这一时期。御史一职起源于西周,主掌祭祀与文书,监察职能居于次要。秦汉时期,御史监察制度初具规模。魏晋南北朝时期,由于时代背景等影响,御史监察制度不... 详细信息

魏晋南北朝是御史监察制度的重要发展阶段,御史监察制度的系统化、规范化就发生在这一时期。御史一职起源于西周,主掌祭祀与文书,监察职能居于次要。秦汉时期,御史监察制度初具规模。魏晋南北朝时期,由于时代背景等影响,御史监察制度不得不进行变革以适应统治者需求、社会变迁需要。这些变化使得御史监察制度呈现出成熟化趋势,为隋唐时期的最终定型打下了坚实基础。

关键词：衰微变革影响

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Effects of Shenqi Xiangyi granules in advanced gastric cancer chemotherapy

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 169-175页

作者： Xiao-jing shi Yu Song Xue-Xue Liang Ting Chen Huang-Yu Hao Xue Han Ya-Nan Chen Department of Oncology Zhangjiagang First People's HospitalSuzhou 215600Jiangsu ProvinceChina

BACKGROUND Owing to the absence of specific symptoms in early-stage gastric cancer,most patients are diagnosed at intermediate or advanced *** a result,treatment often shifts from surgery to other therapies,with chemotherapy and targeted therapies being the primary options for advanced gastric cancer treatment.A total of 116 patients with advanced gastric cancer,admitted from January 2021 to December 2023,were selected and divided into two groups of 58 each using the random number table *** control group received FOLFOX4 chemothe-rapy(oxaliplatin+calcium+folinate+5-fluorouracil)combined with intravenous *** observation group received the same treatment as the control group,supplemented by oral administration of Senqi shiyiwei *** groups underwent treatment cycles of 3 weeks,with a minimum of two *** therapeutic efficacy,immune mechanisms,and treatment-related toxicity and side effects were compared between the *** objective remission rate in the observation group(55.17%)was higher than that of the control group(36.21%)(P0.05).CONCLUSION Adjuvant therapy with Shenqixian granules may enhance the efficacy of simudizumab combined with FOLFOX4 chemotherapy in advanced gastric cancer and the immune function by increasing immune cell counts,making it a valuable option in clinical treatment.

关键词： Sindilizumab FOLFOX4 chemotherapy Advanced gastric cancer Ginseng Qi Xiangyi granule Clinic treatment

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A^2/O工艺反应器水力流态研究

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工业用水与废水 2012年第4期43卷 40-43页

作者：范奎敬世平安徽国祯环保节能科技股份有限公司合肥230088 中国市政工程西南设计研究总院成都610081

为了研究中试A2/O工艺反应器在不同流量条件下的实际HRT、死水区比例及反应器推流及混合效果,采用脉冲示踪法,以NaCl作示踪剂,测试了对反应器的水力流态分布。结果表明,进水流量分别为610、780、1 150 L/h时,厌氧池、缺氧池死水区比例在... 详细信息

为了研究中试A2/O工艺反应器在不同流量条件下的实际HRT、死水区比例及反应器推流及混合效果,采用脉冲示踪法,以NaCl作示踪剂,测试了对反应器的水力流态分布。结果表明,进水流量分别为610、780、1 150 L/h时,厌氧池、缺氧池死水区比例在40%以上,整个生物反应器的死水区比例为20%,反应器在运行过程中,串联级数最高可达8,该反应器有较好的推流作用。

关键词： A2/O工艺反应器水力流态停留时间分布(RTD)

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