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Organochlorine pesticides in soils from the Issyk-Kul region in the western Tian Shan Mountains,Kyrgyzstan：Implication for spatial distribution,source apportionment and ecological risk assessment

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Journal of Mountain Science 2018年第7期15卷 1520-1531页

作者： LI Qian-yu WU jing-lu ZHAO Zhong-hua SAKIEV Kadyrbek State Key Laboratory of Lake Science and Environment Research Nanjing Institute of Geography and Limnology Chinese Academy of Sciences Nanjing 210008 China Ecology and Environment of CentraIAsia Chinese Academy of Sciences Urumqi 830011 China University of Chinese Academy of Sciences Beijing 100039 China Institute of Geology National Academy of Sciences Bishkek 720001 Kyrgyz Republic

As organchlorine pesticides(OCPs) may be an ecologic threat to mountain environments due to their tendency to deposit and accumulate in mountain regions undergoing long-range air transport, OCPs were analyzed in soils collected from an intermontane basin of the western Tian Shan Mountains, which is the UNESCO protected natural reserve of Issyk-Kul. Total OCP concentrations in the Issyk-Kul region ranged from 4.63 to 414 ng/g dw, of which two extraordinary high OCP concentrations(414 ng/g dw and 213 ng/g dw, respectively) influenced by an abandoned dumping site and urban sewage, respectively, were found. Principal component analysis(PCA) and correlation analysis inferred that the OCP inputs in the east of the Issyk-Kul region were mainly from local endogenous sources, and exogenous input via LRAT processes were prominent in the west and south. Additionally, the isomeric and parent substance/metabolite ratios revealed most pesticides accumulated in this region were from old usage, while DDTs had fresh input because of possibly illegal regional application and a slow degradation from the dumping site. Furthermore, ecological risk assessment revealed that no frequently adverse ecological effects were observed in the Issyk-Kul region, but potential risks on neighbouring organisms induced by p,p'-DDT and γ-HCH in dumping site and urban sewage should be considered when devising an efficient management plan to prevent secondary pollution.

关键词： Organchlorine pesticides Pesticide distribution Pesticide sources Ecological risks Issyk-Kul region Tian Shan Mountains

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Energy beam-based direct and assisted polishing techniques for diamond:A review

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International Journal of Extreme Manufacturing 2024年第1期6卷 93-124页

作者： Zhuo Li Feng Jiang Zhengyi Jiang Zige Tian Tian Qiu Tao Zhang Qiuling Wen Xizhao lu jing lu Hui Huang Institute of Manufacturing Engineering Huaqiao UniversityXiamen 361021People’s Republic of China School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongWollongongNSW 2522Australia College of Mechanical Engineering and Automation Huaqiao UniversityXiamen 361021People’s Republic of China State Key Laboratory of High Performance Tools Huaqiao UniversityXiamen 361021People’s Republic of China

Diamond is a highly valuable material with diverse industrial applications,particularly in the fields of semiconductor,optics,and high-power ***,its high hardness and chemical stability make it difficult to realize high-efficiency and ultra-low damage machining of *** address these challenges,several polishing methods have been developed for both single crystal diamond(SCD)and polycrystalline diamond(PCD),including mechanical,chemical,laser,and ion beam processing *** this review,the characteristics and application scope of various polishing technologies for SCD and PCD are ***,various energy beam-based direct and assisted polishing technologies,such as laser polishing,ion beam polishing,plasma-assisted polishing,and laser-assisted polishing,are *** current research progress,material removal mechanism,and infuencing factors of each polishing technology are *** some of these methods can achieve high material removal rates or reduce surface roughness,no single method can meet all the ***,the future development prospects and application directions of different polishing technologies are presented.

关键词： single crystal diamond polycrystalline diamond energy beam polishing technology material removal mechanism influencing factors

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Protective effect of brain and muscle arnt-like protein-1 against ethanol-induced ferroptosis by activating Nrf2 in mice liver and HepG2 cells

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Food Science and Human Wellness 2023年第6期12卷 2390-2407页

作者： Yanan Zhao Ranran Zhang Ziheng Chen Ziyi Wang Shuang Guan jing lu College of Food Science and Engineering Jilin UniversityChangchun 130062China Key Laboratory of Zoonosis Ministry of EducationCollege of Veterinary MedicineJilin UniversityChangchun 130062China

Alcohol abuse has recently become a serious health concern worldwide,and the incidence of alcoholic liver disease(ALD)is rapidly increasing with high morbidity and *** is a newly recognized form of regulated cell death caused by the iron-dependent accumulation of lipid *** we showed that the circadian clock protein brain and muscle arnt-like protein-1(BMAL1)in hepatocytes is both necessary and sufficient to protect against ALD by mitigating ferroptosis.U pon exposure to alcohol(5%Lieber-DeCarli liquid alcohol diet for 10 days before binged alcohol with 5 g/kg body weight in vivo,300 mmol/L for 12 h in vitro,respectively),the content of iron,reactive oxygen species(ROS)and malondialdehyde(MDA)was boosted signifi cantly while glutathione(GSH)was decreased that mainly based on the downregulated protein expression of ferritin heavy chain(FTH),ferroportin(FPN),heme oxygenase1(HO-1)and anti-cystine/glutamate antiporter(SLC7A11),while these changes could be abolished by ferroptosis inhibitor Ferrostatin-1[Fer-1(5 mg/kg body weight for 10 days in vivo,10μmol/L for 2 h in vitro,respectively)].Further study indicated that the alcohol could activate the protein expression of BMAL1 which exerts a protective effect against ferroptosis through promoting nuclear factor erythroid 2-related factor 2(Nrf2)translocation into nuclear and subsequently stimulating its downstream proteins FTH,FPN,glutathione peroxidase 4 activity(GPX4),HO-1,SLC7A11,while knockdown of BMAL1 and Nrf2 by RNA interference further downregulated the expression of these protein and thus promoting ferroptosis in response to ***,our results unveiled that the protective action of BMAL1 during alcohol challenge depends on its ability to activate Nrf2-ARE antiferroptosis pathway and targeting hepatic BMAL1 to dampen hepatic ferroptosis signaling may have therapeutic potential for ALD.

关键词： BMAL1 Ferroptosis Alcohol Nrf2 Mice liver HepG2 cells

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SnO/SnO_(2) heterojunction:an alternative candidate for sensing NO_(2) with fast response at room temperature

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Frontiers of Materials Science 2022年第3期16卷 193-202页

作者： Pengtao WANG Wanyin GE Xiaohua JIA jingtao HUANG Xinmeng ZHANG jing lu School of Materials Science and Engineering Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic MaterialsShaanxi University of Science and TechnologyXi'an 710021China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

The SnO_(2)-based family is a traditional but important gas-sensitive ***,the requirement for high working temperature limits its practical *** work has been done to explore ways to improve its gas-sensing performance at room temperature(RT).For this report,SnO_(2),SnO,and SnO/SnO_(2) heterojunction was successfully synthesized by a facile hydrothermal combined with subsequent *** SnO_(2) requires a high operating temperature(145℃),while SnO/SnO_(2) heterojunction exhibits an excellent performance for sensing NO_(2) at ***,SnO/SnO_(2) exhibits a fast response,of 32 s,to 50 ppm NO_(2) at RT(27℃),which is much faster than that of SnO(139 s).The superior sensing properties of SnO/SnO_(2) heterojunction are attributed to the unique hierarchical structures,large number of adsorption sites,and enhanced electron *** results show that SnO/SnO_(2) heterojunction can be used as a promising high-performance NO_(2) sensitive material at RT.

关键词： SnO SnO_(2) heterostructure NO_(2) roomtemperature

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Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles

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Journal of Pharmaceutical Analysis 2023年第4期13卷 340-354页

作者： Duanping Sun Ying Ma Maoqiang Wu Zuanguang Chen luyong Zhang jing lu Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances Center for Drug Research and DevelopmentGuangdong Pharmaceutical UniversityGuangzhou510006China Key Specialty of Clinical Pharmacy The First Affiliated Hospital of Guangdong Pharmaceutical UniversityGuangzhou510699China National and Local United Engineering Lab of Druggability and New Drugs Evaluation School of Pharmaceutical SciencesSun Yat-Sen UniversityGuangzhou510006China

Liquid biopsy is a technology that exhibits potential to detect cancer early,monitor therapies,and predict cancer prognosis due to its unique characteristics,including noninvasive sampling and real-time *** tumor cells(CTCs)and extracellular vesicles(EVs)are two important components of circulating targets,carrying substantial disease-related molecular information and playing a key role in liquid *** are single-stranded oligonucleotides with superior affinity and specificity,and they can bind to targets by folding into unique tertiary ***-based microfluidic platforms offer new ways to enhance the purity and capture efficiency of CTCs and EVs by combining the advantages of microfluidic chips as isolation platforms and aptamers as recognition *** this review,we first briefly introduce some new strategies for aptamer discovery based on traditional and aptamer-based microfluidic ***,we subsequently summarize the progress of aptamer-based microfluidics for CTC and EV ***,we offer an outlook on the future directional challenges of aptamer-based microfluidics for circulating targets in clinical applications.

关键词： Aptamer Microfluidic Circulating tumor cells Extracellular vesicles Bioanalysis

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Hyperbolic Dependence of Moment of Inertia onω2 in Bands Involving vi13/2 Orbital and its Application in Configuration Identification

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Chinese Physics Letters 2000年第4期17卷 261-263页

作者： lu jing-Bin LIU Yun-Zuo ZHANG Fan Department of Physics Jilin UniversityChangchun 130023 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000

The so-called hyperbolic dependence of apparent moment of inertia on square of rotational frequency is developed to the bands involving^13/2 quasineutron around A-60 lighter rare-earth *** can be explained as a characteristic of strongly Coriolis mixing in the high-j unique-parity *** applications of such an effectj the previously proposed assignments of band x of^(160)Ho,π1/2^(-)[541]■vi_(13/2)band of^(170)Ta,as well as band B of 168lu have been reviewed respectively.

关键词： bands Hyperbolic Configuration

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Non-Markovianity of an atom in a semi-infinite rectangular waveguide

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Chinese Physics B 2023年第3期32卷 102-110页

作者：曾静宋亚菊卢竞周兰 Key Laboratory of Low-Dimensional Quantum Structures and and Quantum Control of the Ministry of Education Department of Physics and Synergetic Innovation Center of Quantum Effects and ApplicationsKey Laboratory for Matter Microstructure and Function of Hunan ProvinceHunan Normal UniversityChangsha 410081China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421002China

We investigate the non-Markovianity(NM)of a waveguide QED with a two-level atom as the system and a semiinfinite rectangular waveguide as the environment,where the transverse magnetic(TM_(mn))modes define the quantum channels of guided *** perfect mirror imposed by the finite end exerts a retarded feedback mechanism to allow for information backflow,which leads to NM *** the energy separation of the atom far away from the cutoff frequencies of transverse modes,the delay differential equations are obtained with single-excitation initial in the *** attention is focused on the effects of multiple quantum channels involved in guiding photons on the degree of nonMarkovian *** asymptotic value of the non-Markovianity N_(1)can be found as the atom–mirror distance is large enough,however,the asymptotic value of N_(2)of the atom interacting with the effective double-modes is lower than that of the atom interacting with the effective *** also show that N_(1)is a constant,and the analytical expression for N_(2)is related to the parameters associated with the modes,which is related to the interference of the two modes.

关键词： open system non-Markovianity waveguide QED quantum information

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Liquid Chromatographic Assay of Peptides Activity with Inhibiting Angiotensin Converting Enzyme

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Chemical Research in Chinese Universities 2010年第5期26卷 712-716页

作者： LIU jing-bo YU Zhi-peng ZHAO Wen-zhu lu jing CHEN Feng LIN Song-yi Laboratory of Nutrition and Functional Food Jilin University Changehun 130062 P. R. China Department of Food Science and Human Nutrition Clemson University Clemson SC 29634 USA

A rapid, simple and interference-free method was developed to evaluate the inhibitory activity of hydrolyzed peptides from egg white protein against the angiotensin-converting enzyme. The total reaction volume was 60 μL, saving the cost. The assay was based on a HPLC separation and quantification of the synthetic substrate hippuryl-L-histidyl-L-leucine and its hydrolyzed product-hippuric acid; the separation was performed on a C18 column eluted by a mobile phase of acetonitrile/water（0.5% TFA） at a volume ratio of 25：75. At a signal to noise ratio（S/N） of 10, the detective limit of the quantitation of hippuric acid was （0.4600±0.0097） μmol/L. The standard curve shows a linear response with a slope of 49488 and a correlation coefficient of 0.9995. The assay was adequate for the study of ACE inhibition by Captopril and peptides derived from food protein, and showed a very good correlation with the previous methods.

关键词： Angiotensin converting enzyme HPLC Egg white protein Peptide

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Selection of Single-Walled Carbon Nanotubes According to Both Their Diameter and Chirality via Nanotweezers

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Nano Research 2010年第4期3卷 296-306页

作者： jing Zhou Hong Li jing lu Guangfu luo Lin Lai Rui Qin lu Wang Shigeru Nagase Zhengxiang Gao Waining Mei Guangping Li Dapeng Yu Stefano Sanvito State Key Laboratory of Mesoscopic Physics and Department of Physics Peking UniversityBeijing 100871China Department of Theoretical Molecular Science Institute for Molecular ScienceOkazaki 444-8585Japan Department of Physics University of Nebraska at OmahaOmahaNebraska 68182-0266USA SICAS Center Lee HallSUNY OneontaOneontaNY 13820USA School of Physics and CRANN Trinity CollegeDublin 2Ireland

Diameter- and chirality-dependent interactions between aromatic molecule-based nanotweezers and single-walled carbon nanotubes (SWNTs) are revealed by density functional theory calculations. We found that the threshold diameter of selected SWNTs is determined by the end-to-end distance of the nanotweezer. Large-diameter SWNTs are preferred by a nanotweezer with an obtuse folding angle, whereas small-diameter SWNTs are favored by a nanotweezer with an acute folding angle. The adsorption can be further stabilized by the orientational alignment of the hexagonal rings of the nanotweezer and the SWNT sidewall. Therefore, by taking advantage of the supramolecular recognition ability of the aromatic molecule-based nanotweezer, SWNTs can be enriched with both controllable diameter and chirality.

关键词： Carbon nanotubes nanotweezer selective adsorption density functional theory

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A rapid and efficient synthesis of indoloquinolinone and its analogues under microwave irradiation

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Chinese Chemical Letters 2008年第5期19卷 518-520页

作者： Yu jing lu Ning Sun Zhi Shu Huang Lian Quan Gu School of Pharmaceutical Sciences Sun Yat-sen University Guangzhou 510275 China

A rapid and efficient method was established for the synthesis of indoloquinolinone and its analogues using acid-promoted cyclization in the present of PPA. All the reactions were completed in good yields in lOmin und... 详细信息

关键词： Indoloquinolinone analogues Synthesis Microwave irradiation PPA

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