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Microstructure and deformation mechanism of dual-phase Al_(0.5)CoCrNiFe high-entropy alloy

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Rare Metals 2023年第6期42卷 2020-2027页

作者： Yong-Gang Tong Nan Tian Hong-Feng Huang Zhi-Bin Zhang Xiu-Bing Liang Xi-Xi Ji jing-zhong fang Yong-Le Hu College of Automotive and Mechanical Engineering Changsha University of Science and TechnologyChangsha410114China Key Laboratory of New Processing Technology for Nonferrous Metal and Materials Guilin University of TechnologyMinistry of EducationGuilin541004China National Institute of Defense Technology Innovation Academy of Military Sciences PLA ChinaBeijing100071China

Dual-phase high-entropy alloys containing facecentered cubic(fcc) and body-centered cubic(bcc) phases achieve a combination of high strength and high ductility,which attract extensive *** with singlephase high-entropy alloys,the dual-phase structure generates more complex deformation mechanisms such as structural transformation and interactions between grain boundaries and dislocations during *** order to understand the structural transformation of the dual-phase high-entropy alloy during deformation and its effect on mechanical properties,Al_(0.5)CoCrNiFe high-entropy alloy was prepared and its deformation mechanism was investigated by molecular dynamics simulations combined with *** results show that phase transformation occurred during deformation,and dislocation slip was the main deformation *** addition,there was significant dislocation pile-up at the interface between fcc and bcc phases after tensile *** and strain rates significantly affected the mechanical properties and deformation behavior of high-entropy *** low temperature and high strain rate,the dislocation density of the alloy increases after stretching,resulting in the enhancement of tensile strength.

关键词： Dual-phase high-entropy alloy(HEA) Microstructure Deformation behavior Dislocation

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑Yuan Yu jing Wu Guang Yin Fan‑Zhen Jiao zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

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Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting Qiu Na Li Zhengxiang Zhou Ru Ye Liyan zhong Yashuang Xu Junhui Ren Yi Liang Xiaomei Shao Jianqiao fang Junfan fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie jing Zhang Xue fang Hongmei Luo Chuanhai Fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

10-HDA对原代培养大鼠海马神经元增殖的研究

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山西大学学报(自然科学版) 2010年第2期33卷 282-285页

作者：田静钟方旭武汉工业学院生物与制药工程学院

研究10-HDA对原代培养新生大鼠海马神经元的增殖效果.原代培养24 h的新生大鼠海马神经元,通过添加不同浓度的10-HDA（0.1μmol/L、1.0μmol/L、10μmol/L）作用后,利用BrdU免疫荧光染色检测神经细胞增殖,尼氏染色观察神经元数量的变化.... 详细信息

研究10-HDA对原代培养新生大鼠海马神经元的增殖效果.原代培养24 h的新生大鼠海马神经元,通过添加不同浓度的10-HDA（0.1μmol/L、1.0μmol/L、10μmol/L）作用后,利用BrdU免疫荧光染色检测神经细胞增殖,尼氏染色观察神经元数量的变化.结果显示中剂量浓度（1.0μmol/L）的10-HDA作用海马神经元24h后,细胞数量明显增多;而高浓度（10μmol/L）10-HDA作用海马神经元24 h后,细胞数量明显低于正常对照组和低剂量组（0.1μmol/L）.BrdU免疫荧光染色表明,中剂量浓度的10-HDA可使细胞增殖,增殖率达到（19.37±2.192 1）%.尼氏染色结果表明,10-HDA使海马神经元数量增加了（20.31±4.086 5）%.研究结果表明,10-HDA对原代培养的海马神经元有增殖作用.

关键词： 10-HDA 海马细胞增殖

The low-latitude sodium layer:comparative data from lidar observations at Hainan,China and São Paulo,Brazil

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Earth and Planetary Physics 2025年第1期9卷 39-53页

作者： fang Wu jing Jiao GuoTao Yang Lifang Du ZhengKuan Liu HaoRan Zheng JiXin Guo ShaoHua Gong YaJun Zhu State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China Hainan National Field Science Observation and Research Observatory for Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China China-Brazil Joint Laboratory for Space Weather NSSC/INPESão Josédos Campos 12227-010Brazil School of Physics and Electronics Engineering Hainan Normal UniversityHaikou 571158China

Physical and chemical processes observed in the mesosphere and thermosphere above the Earth’s low latitudes are complex and highly interrelated to activity in the low-latitude *** sodium detected by lidar can yield clues to dynamic and chemical processes in these spatial layers above the Earth’s *** paper is based on sodium layer data collected at two low-latitude stations,one in the northern hemisphere and one in the *** low-latitude sodium layer exhibits conspicuous seasonal variations in shape,density,and altitude;these variations are similar between Earth’s hemispheres:sodium layer density at both stations reaches its seasonal maximum in autumn and minimum in ***,maximal Na density over Brazil is greater than that over *** variations of Na density above the two low-latitude stations are also similar;at both,maxima are observed before *** variations of the Na layer over Brazil that differ from those observed in the northern hemisphere may be related to the South Atlantic Magnetic Anomaly(SAMA)or fountain *** suggest that low-latitude Na layer data may provide useful additional evidence that could significantly improve the low-latitude part of the WACCM-Na model.

关键词： metallic sodium layer seasonal variation nocturnal variation lidar

数字素养对老年人主观福利的影响——基于新人力资本理论的研究视角

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山西财经大学学报 2025年第1期47卷 31-47页

作者：杨仲山初放东北财经大学统计学院

利用中国家庭追踪调查（CFPS）数据，基于新人力资本理论分析数字素养对老年人主观福利的影响。研究显示：数字素养对老年人主观福利有显著的促进作用，但对于幸福感、生活满意度、婚姻满意度和抑郁程度等主观福利的重要部分影响并不一... 详细信息

利用中国家庭追踪调查（CFPS）数据，基于新人力资本理论分析数字素养对老年人主观福利的影响。研究显示：数字素养对老年人主观福利有显著的促进作用，但对于幸福感、生活满意度、婚姻满意度和抑郁程度等主观福利的重要部分影响并不一致；数字素养可通过提升老年人的认知能力和非认知能力进而对主观福利起到正向作用；具有高严谨性、高外倾性、低宜人性的老年人更容易获得主观福利，情绪稳定的老年人更不容易抑郁。

关键词：数字素养主观福利认知能力非认知能力老龄化新人力资本大五人格生活满意度

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao fang Qiuxia Peng Wen Qin Xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Research on fixed-time time-varying formation of heterogeneous multi-agent systems based on tracking error observer under DoS attacks

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Defence Technology（防务技术） 2024年第12期42卷 211-225页

作者： Jiqing Luo Husheng fang Yue zhong jing Zhang Shengli Song Army Engineering University of PLA Nanjing 210000China Unit 63966 of PLA Beijing 100000China

In this paper,the fixed-time time-varying formation of heterogeneous multi-agent systems(MASs) based on tracking error observer under denial-of-service(DoS) attacks is ***,the dynamic pinning strategy is used to reconstruct the communication channel for the system that suffers from DoS attacks to prevent the discontinuous transmission information of the communication network from affecting MASs ***,considering that the leader state is not available to each follower under DoS attacks,a fixed-time distributed observer without velocity information is constructed to estimate the tracking error between followers and the ***,adaptive radial basis function neural network(RBFNN) is used to approximate the unknown ensemble disturbances in the system,and the fixed-time time-varying formation scheme is designed with the constructed *** effectiveness of the proposed control algorithm is demonstrated by the numerical simulation.

关键词： Denial-of-service attacks Dynamic pinning Fixed-time tracking error observer Adaptive RBFNN Fixed-time time-varying formation