检索结果-南通市图书馆

Surface embedded binary Co-Cu hydroxy phosphate over surface of oxy/hydroxides for efficient nitrate reduction to ammonia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 195-207页

作者： Chun Zhu yifei Yang yike jing Zhen Zeng Xuesong yi Wei Sun Fei Yang Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province School of Environmental Science and EngineeringHainan UniversityHaikou 570228China

Electrochemical nitrate reduction reaction(NO3RR)to ammonia is a promising approach to address excess Ncontamination in aqueous environment but suffers from a limited ammonia yield and selectivity due to the low concentration and sluggish *** work reports a three-dimensional porous electrode with binary Co_(2)Cu_(1)hydroxy phosphate embedded into the surface of Ni_(3)Co_(1)oxy/hydroxides(CoCu-PH@NiCo/Ni,“PH”means phosphate-hydroxide),which delivers a yield of 4.13 mg·h^(-1)·cm^(-2)with a high Faraday efficiency of 92.6%under a low nitrate concentration of 40 mM and provide an impressive *** embedded structure of the as-prepared catalyst exhibits unique metal coordination ligands and valence states different from the unitary *** electrochemical in situ infrared spectra and theoretical calculations revealed that the Co sites with the ability to dissociate water molecular to form adsorbed OH*can effectively provide the required protons for the deoxygenation and hydrogenation steps during NO3-conversion,thereby,effectively reducing the energy barrier of the key transition states in the NO3RR process to improve the intrinsic *** demonstrate that the rational design of binary components with the appropriate ability to activate water molecules as well as the threedimensional porous skeletal structure are expected to promote effectively the low-concentration nitrates conversion to ammonia.

关键词： nitrate reduction hydroxy phosphate surface embedded water dissociation active hydroxy adsorbed

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一种LVDS-光纤接口转换器的设计与实现

仪表技术与传感器 2018年第5期 35-38页

作者：王红亮曹京胜陈一波仪器科学与动态测试教育部重点实验室山西太原030051

针对目前多数基于SFP光纤接口的高速传感器存储测试设备无法与频谱分析仪直接通信的现状,设计了一种基于FPGA的LVDS-光纤接口转换器。通过FPGA编程实现LVDS接口数据包和光纤接口数据包编码转换,利用DDR3对数据进行乒乓操作达到高速缓存... 详细信息

针对目前多数基于SFP光纤接口的高速传感器存储测试设备无法与频谱分析仪直接通信的现状,设计了一种基于FPGA的LVDS-光纤接口转换器。通过FPGA编程实现LVDS接口数据包和光纤接口数据包编码转换,利用DDR3对数据进行乒乓操作达到高速缓存目的,实现了频谱分析仪与高速存储测试设备间双工通信。经长时间实际测试没有出现误码,表明该转换器设计合理高效。

关键词： LVDS接口光纤接口接口转换高速接口 DDR3 乒乓操作

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma yi-Xiang He jing Jin Hong-Lian Wang Yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

莫沙必利联合奥美拉唑镁治疗反流性食管炎患者的临床研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学杂志 2022年第24期38卷 2941-2945页

作者：邹会汪照函盛景义方丽娟黄宽忠景德镇市中医医院消化内科江西景德镇333000 江西省人民医院消化内科江西南昌330006 景德镇市第一人民医院消化内科江西景德镇333000

目的观察莫沙必利联合奥美拉唑镁治疗反流性食管炎、改善患者胃肠激素水平的效果及安全性。方法将72例反流性食管炎患者随机分为试验组36例和对照组36例。对照组给予艾司奥美拉唑镁肠溶片,每次20 mg,每天2次,口服。试验组在对照组的... 详细信息

目的观察莫沙必利联合奥美拉唑镁治疗反流性食管炎、改善患者胃肠激素水平的效果及安全性。方法将72例反流性食管炎患者随机分为试验组36例和对照组36例。对照组给予艾司奥美拉唑镁肠溶片,每次20 mg,每天2次,口服。试验组在对照组的基础上加用枸橼酸莫沙必利片,每次5 mg,每天3次,口服。2组均治疗2个月,并随访3个月。观察2组患者治疗后的临床疗效,观察治疗前后胃肠激素、血清疾病相关因子水平和治疗期间的药物不良反应发生情况,随访3个月复发情况。结果治疗后,试验组和对照组的总有效率分别为94.29%和74.29%,差异有统计学意义(P5 min次数为(1.60±0.28)和(2.91±0.25)次;pH值0.05)。试验组、对照组患者随访3个月复发率分别为3.03%和26.92%,试验组复发率低于对照组(P<0.05)。结论莫沙必利联合奥美拉唑镁治疗反流性食管炎具有较好的临床疗效,可改善患者胃肠激素、血清疾病相关因子水平,进而改善反流情况,复发率较低,安全性高。

关键词：反流性食管炎莫沙必利质子泵抑制药胃肠激素疾病相关因子

Building Magnetoresponsive Composite Elastomers for Bionic Locomotion Applications

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2020年第3期17卷 405-420页

作者： yi Lei Zhizhi sheng Jian Zhang jing Liu Wei Lv Xu Hou Department of Physics Research Institute for Biomimetics and Soft MatterJiujiang Research InstituteCollege o f Physical Science and TechnologyXiamen UniversityXiamen 361005China State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Collaborative Innovation Center of Chemistry for Energy Materials Xiamen UniversityXiamen 361005China

The ability of natural living organisms,transferring deformations into locomotion,has attracted researchers’increasing attention in building bionic actuators and smart *** a typical category of functional materials,magnetoresponsive composite elastomers,comprised of flexible elastomer matrices and rigid magnetic particles,have been playing critical roles in this field of research due to their dynamic changes in response to applied magnetic field direction and *** magnetically driven bionic actuators based on magnetoresponsive composite elastomers have been developed to achieve some specific functions in some special *** instance,under the control of the applied magnetic field,the bionic actuators can not only generate time-varying deformation,but also motion in diverse environments,suggesting new possibilities for target gripping and directional transporting especially in the field of artificial soft robots and biological ***,this review comprehensively introduces the component,fabrication,and bionic locomotion application of magnetoresponsive composite ***,existing challenges and future perspectives are further discussed.

关键词： magnetoresponsive composite elastomers components fabrication bionic locomotion

Synthesis and insecticidal activities of 1,8-naphthyridine derivatives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2017年第8期28卷 1723-1726页

作者： Qing-Qing Hou yi-Fei jing Xu-sheng Shao Shanghai Key Laboratory of Chemical Biology School of PharmacyEast China University of Science and TechnologyShanghai 200237China

1,8-Naphthyridines（NAP） are biological important scaffolds in bioactive molecules design. By hybrid of NAP with neonicotinoid core structure, nine novel NAP derivatives were synthesized and subjected to insecticidal activities evaluation. Some of the compounds showed excellent insecticidal activity against cowpea aphids（Aphis craccivora） with LC_（50） values ranging from 0.011 mmol/L to 0.067 mmol/L. The results indicated that 1,8-naphthyridine can be used as insecticidal structure for further modification.

关键词： 1.8-Naphthyridine Insecticide ativity Neonicotinoid Aphid

Schisandrin B Protects against Ischemic Brain Damage by Regulating PI3K/AKT Signaling in Rats

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2023年第10期29卷 885-894页

作者： HONG Quan-long DING yi-hang CHEN jing-yi SHI Song-sheng LIANG Ri-sheng TU Xian-kun Department of Neurology The First Hospital of Quanzhou Affiliated to Fujian Medical UniversityQuanzhouFujian Province362000China Department of Neurosurgery Fujian Medical University Union HospitalFuzhou350001China

Objective To explore the effect and mechanism of schisandrin B(Sch B)in the treatment of cerebral ischemia in *** The cerebral ischemia models were induced by middle cerebral artery occlusion(MCAO)and ***-Dawley rats were divided into 6 groups using a random number table,including sham,MCAO,MCAO+Sch B(50 mg/kg),MCAO+Sch B(100 mg/kg),MCAO+Sch B(100 mg/kg)+LY294002,and MCAO+Sch B(100 mg/kg)+wortmannin *** effects of Sch B on pathological indicators,including neurological deficit scores,cerebral infarct volume,and brain edema,were subsequently *** apoptosis was identified by terminal transferase-mediated dUTP nick end-labeling(TUNEL)*** protein expressions involved in apoptosis,inflammation response and oxidative stress were examined by immunofluorescent staining,biochemical analysis and Western blot analysis,*** effect of Sch B on phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT)signaling was also *** Sch B treatment decreased neurological deficit scores,cerebral water content,and infarct volume in MCAO rats(P<0.05 or P<0.01).Neuronal nuclei and TUNEL staining indicated that Sch B also reduced apoptosis in brain tissues,as well as the Bax/Bcl-2 ratio and caspase-3 expression(P<0.01).Sch B regulated the production of myeloperoxidase,malondialdehyde,nitric oxide and superoxide dismutase,as well as the release of cytokine interleukin(IL)-1βand IL-18,in MCAO rats(P<0.05 or P<0.01).Sch B promoted the phosphorylation of PI3K and *** the PI3K/AKT signaling pathway with LY294002 or wortmannin reduced the protective effect of Sch B against cerebral ischemia(P<0.05 or P<0.01).Conclusions Sch B reduced apoptosis,inflammatory response,and oxidative stress of MCAO rats by modulating the PI3K/AKT *** B had a potential for treating cerebral ischemia.

关键词： cerebral ischemia inflammation neuroprotection PI3K/AKT signaling schisandrin B Chinese medicine

Development and simulation of a gridded thermionic cathode electron gun for a high-energy photon source

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2023年第3期34卷 73-81页

作者： sheng-Chang Wang Da-Yong He Cai Meng jing-yi Li Zu-sheng Zhou Jin-Dong Liu Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

A gridded thermionic cathode electron gun was developed for the linear accelerator of the High Energy Photon Source(HEPS).An electron gun should provide a large maximum bunch charge with a wide adjustable *** satisfy these requirements,the shape of the electrode was optimized using a multi-objective genetic algorithm.A large bunch charge with an adjustable range was achieved using the grid-limited gun,the flow of which was analyzed using 3-D *** electron gun has been manufactured and tested,and the measured data of the grid-limited current and simulation results are compared and discussed in this study.

关键词： Electron gun Multi-objective genetic algorithm Grid CST

Ultra-early amplitude decrement after repetitive nerve stimulation supports early neuromuscular junction injury in amyotrophic lateral sclerosis:a prospective cross-sectional study

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第3期17卷 655-660页

作者： jing-Yue Ma Xiang-yi Liu Shuo Zhang Dong-sheng Fan Department of Neurology Peking University Third HospitalBeijingChina Beijing Municipal Key Laboratory of Biomarker and Translational Research in Neurodegenerative Diseases BeijingChina

The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral sclerosis occurs at the earliest stage of the *** basic studies have confirmed early damage to neuromuscular junctions,but it is difficult to obtain such evidence directly in clinical *** this prospective cross-sectional study,we recruited 22 patients with early amyotrophic lateral sclerosis with disease duration < 12 months and with clinical symptoms limited to the upper *** also recruited 32 healthy *** nerve stimulation was performed,and patients were followed for 12 *** found a significant change in the response to repetitive nerve stimulation in amyotrophic lateral sclerosis patients without spontaneous electromyographic *** that were prone to denervation had an increased decrement response of target muscles after repetitive nerve *** results suggest that changes in response to repetitive nerve stimulation may occur before denervation in amyotrophic lateral sclerosis *** damage to lower motor neurons is more obvious in patients with a higher percentage of repetitive never stimulation-related amplitude *** study was approved by the Institutional Ethics Committee of Peking University Third Hospital(approval No.M2017198) on August 24,2017.

关键词： amplitude decremental response amyotrophic lateral sclerosis dying-back hypothesis motor neuron disease nerve electrophysiology physiopathology prognosis repetitive nerve stimulation