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Surface demineralized freeze-dried bone allograft followed by reimplantation in a failed mandibular dental implant

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Regenerative Biomaterials 2024年第1期3卷 82-93页

作者： jing Zhang Jie Wang Jiayi You Xuan qin Huimin chen Xiantong Hu Yantao Zhao Yang Xia Jiangsu Key Laboratory of Oral Diseases Nanjing Medical UniversityNanjingJiangsu 210029PR China Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing Medical UniversityNanjingJiangsu 210029PR China Department of Restorative Dental Sciences Faculty of DentistryThe University of Hong KongHong Kong SARPR China Senior Department of Orthopedics The Fourth Medical Center of PLA General HospitalBeijing100048PR China Beijing Engineering Research Center of Orthopedics Implants Beijing 100048PR China State Key Laboratory of Military Stomatology Xi'an 710032PR China

The removal of a failed implant with high torque causes significant damage to the surrounding tissue,compromising bone regeneration and subsequent osseointegration in the defect ***,we report a case of carrier screw fracture followed by immediate implant removal,bone grafting and delayed reimplantation.A dental implant with a fractured central carrier screw was removed using the bur-forceps *** resulting three-wall bone defect was filled with granular surface demineralized freeze-dried bone allograft(SD-FDBA).Cone-beam computerized tomography was performed at 1week,6months and 15months postoperatively and standardized for quantitative *** alveolar bone width and height at 15months post-surgery were about 91%of the original values,with a slightly lower bone density,calculated using the gray value *** graft site was reopened and was found to be completely healed with dense and vascularized bone along with some residual bone *** followed by restoration was performed 8months *** quality of regenerated bone following SD-FDBA grafting was adequate for osseointegration and longterm implant *** excellent osteogenic properties of SD-FDBA are attributed to its human origin,cortical bone-like structure,partly demineralized surfaces and bone morphogenetic protein-2-containing *** investigation with more cases and longer follow-up was required to confirm the final clinical effect.

关键词： dental implant implant failure allogeneic bone bone regeneration reimplantation

Singular analysis of bifurcation systems with two parameters

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Acta Mechanica Sinica 2010年第3期26卷 501-507页

作者： Zhaohong qin Yushu chen School of Astronautics Harbin Institute of Technology 150001 Harbin China

Bifurcation properties of dynamical systems with two parameters are investigated in this paper. The definition of transition set is proposed, and the approach developed is used to investigate the dynamic characteristic of the nonlin- ear forced Duffing system with nonlinear feedback controller. The whole parametric plane is divided into several persistent regions by the transition set, and then the bifurcation dia- grams in different persistent regions are obtained.

关键词： Two parameters Bifurcation Singular analysis

Progress and current perspectives of diagnosis and treatment of hepatoid adenocarcinoma of the stomach

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Oncology and Translational Medicine 2024年第2期10卷 54-59页

作者： Kai qin jing Zhang chen Gong Yi cheng Department of Oncology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Hepatoid adenocarcinoma of the stomach(HAS)is a rare malignant gastric tumor exhibiting both hepatocellular and adenocarcinomatous *** are often diagnosed at an advanced stage,and their clinical symptoms closely resemble those of gastric *** of its rarity,misdiagnosis and missed diagnoses are *** with gastric adenocarcinoma,HAS typically exhibits higher invasiveness and amore unfavorable *** review aimed to elaborate on the pathological features,potential mechanisms,clinical characteristics,diagnosis,and prognosis of *** insights provided aimed to contribute robust guidance for the clinical management of patients with HAS.

关键词： Diagnosis Hepatoid adenocarcinoma of the stomach Progress

Space-time prisms in multimodal supernetwork-Part 2:Application for analyses of accessibility and equality

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Communications in Transportation Research 2022年第1期2卷 58-65页

作者： jing qin Feixiong Liao Urban Planning and Transportation Group Eindhoven University of Technologythe Netherlands

Space-time prism(STP)is a fundamental concept in time geography and has been predominately constructed in unimodal transportation *** to the vast trip chaining options by private vehicles and public transportation,it was challenging to construct STP over multimodal transportation *** previously put forward an efficient method to narrow down the action space for trip chaining and construct STPs effectively in a multimodal *** study applies multimodal STP modeling to measure space-time accessibility and equality of daily activity *** equality measures(Gini coefficient and 20:20 ratio)are derived from two space-time accessibility measures based on delineated *** examine the equality of access to shopping and leisure opportunities in the Rotterdam-The Hague metropolitan area,the *** results show the effects of various factors on accessibility and *** is found that although the study area has relatively low inequality using single modes,multimodal trip chaining further reduces inequality to access the distributed space-time opportunities.

关键词： Space-time prism Accessibility Equality Multimodal supernetwork

Space-time prism in multimodal supernetwork-Part 1:Methodology

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Communications in Transportation Research 2021年第1期1卷 130-138页

作者： jing qin Feixiong Liao Urban Planning and Transportation Group Eindhoven University of TechnologyEindhoven5600 MBthe Netherlands

Space-time prism(STP)modeling offers a theoretical base for various person-based space-time accessibility *** has been challenging to construct STPs in multimodal transportation networks because of the vast multimodal trip chaining options between private vehicles and public *** study suggests an effective method for narrowing down the trip chaining *** method involves three incremental strategies to eliminate parking locations that contribute little to enlarging the ***,an upper bound potential path area(PPA)is constructed to remove all inferior parking ***,the study area is partitioned and only complementary parking locations attractive to trip chaining are ***,triangular inequalities are applied for *** selected parking locations are used to construct a compact multimodal supernetwork encompassing one episode of activity ***,the STP and PPA can be found by an existing twostage bidirectional search *** tests are conducted to demonstrate the effectiveness of the *** is found that 1-2 orders of speedups can be achieved with little compromising the accuracy of measuring space-time *** suggested method is applicable for measuring space-time accessibility in large-scale multimodal transportation networks.

关键词： Space-time prism Accessibility Trip chaining Multimodal supernetwork

Association of COL1A1 polymorphism with high myopia: a Meta-analysis

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International Journal of Ophthalmology(English edition) 2016年第4期9卷 604-609页

作者： Guang-Ming Jin Xiao-jing Zhao Ai-Ming chen Yong-Xing chen qin Li State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Department of Ophthalmology the Fifth Affiliated Hospital of Sun Yat-sen University Department of Pharmacy the Fifth Affiliated Hospital of Sun Yat-sen University Department of Otorhinolaryngology Jiangmen Central Hospital

AIM： To investigate the association between collagen type I alpha 1（COL1A1） gene and high myopia.· METHODS： In this Meta-analysis, we examined 5published case-control studies that involved 1942 high myopia cases and 2929 healthy controls to assess the association between the COL1A1 rs2075555 polymorphism and high myopia risk. We calculated the pooled odds ratios（ORs） of COL1A1 rs2075555 polymorphism in high myopia cases vs healthy controls to evaluate the strength of the association.·RESULTS： Overall, there was no significant difference both in the genotype and allele distributions of COL1A1rs2075555 polymorphism between high myopia cases and healthy controls： CC vs AA OR =1.10, 95% confidence interval（CI）=0.76-1.58; AC vs AA OR=0.98, 95%CI 0.80-1.20; CC/AC vs AA/OR=1.01, 95%CI 0.84-1.22; CC vs AC/AA OR =1.06, 95% CI =0.93-1.20; C vs A OR =1.06, 95% CI0.91-1.23）. In addition, in the stratified analyses by ethnicity, no significant associations were found in any genetic model both in European and Asia cohorts.·CONCLUSION： Our results indicate that the COL1A1rs2075555 polymorphism may not affect susceptibility to high myopia.

关键词： collagen type I alpha 1 polymorphism high myopia Meta-analysis

Hydrogen sulfide-induced post-translational modification as a potential drug target

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Genes & Diseases 2023年第5期10卷 1870-1882页

作者： Hao-Jie chen Lei Qian Ke Li Yang-Zhe qin jing-jing Zhou Xin-Ying Ji Dong-Dong Wu School of Basic Medical Sciences Henan UniversityKaifengHenan 475004China Henan International Joint Laboratory for Nuclear Protein Regulation Henan UniversityKaifengHenan 475004China Kaifeng Key Laboratory of Infection and Biological Safety School of Basic Medical SciencesHenan UniversityKaifengHenan 475004China School of Stomatology Henan UniversityKaifengHenan 475004China

Hydrogen sulfide (H_(2)S) is one of the three known gas signal transducers, and since its potential physiological role was reported, the literature on H_(2)S has been increasing. H_(2)S is involved in processes such as vasodilation, neurotransmission, angiogenesis, inflammation, and the prevention of ischemia-reperfusion injury, and its mechanism remains to be further studied. At present, the role of post-translational processing of proteins has been considered as a possible mechanism for the involvement of H_(2)S in a variety of physiological processes. Current studies have shown that H_(2)S is involved in S-sulfhydration, phosphorylation, and S-nitrosylation of proteins, etc. This paper focuses on the effects of protein modification involving H_(2)S on physiological and pathological processes, looking forward to providing guidance for subsequent research.

关键词： Hydrogen sulfide Modification Phosphorylation S-nitrosylation S-sulfhydration

Numerical analysis on propulsive efficiency and pre-deformated optimization of a composite marine propeller

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Science China(Technological Sciences) 2020年第12期63卷 2562-2574页

作者： ZHANG jing WU qin WANG GuoYu LIU TaoTao School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China

The objectives of this paper are to numerically investigate the performance of a composite propeller through bidirectional FSI algorithm combining CFD and FEM,and to improve its propulsive efficiency by a pre-deformated method. Numerical results are presented for the composite propeller which has been modeled by unidirectionally stacking with glass-fiber reinforced composites. The propulsive efficiency of the composite and rigid propellers with different advance coefficients J has been *** results show that the efficiency of the composite propeller is obviously higher than that of the rigid propeller when J≤0.8,which is attributed to the decrease of pitch angle caused by the bend-twist coupling effects. But for the design condition J=0.851 and the cases with J>0.851,the efficiency of the composite propeller is significantly lower than that of the rigid propeller,which is because the angle of attack αcomposite is deviated from the optimal angle of attack αdesign more than that for the rigid case α*** on the optimization by the proposed pre-deformated method,the efficiency improvement of the composite propeller at the conditions with J≥0.851 could be obtained,and the composite material used in this work can meet the strength requirement of the designed propellers.

关键词： marine propeller computational fluid dynamic(CFD) propulsive efficiency pre-deformated optimization fluid-structure interaction(FSI)

Pseudo-break imaging of carbon nanotubes for determining elastic bending energies

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Nano Research 2023年第5期16卷 7443-7451页

作者： Changfei jing Yongji qin Wengen Ouyang Jun Luo Institute for New Energy Materials and Low-Carbon Technologies and Tianjin Key Lab of Photoelectric Materials and Devices School of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China ShenSi Lab Shenzhen Institute for Advanced StudyUniversity of Electronic Science and Technology of ChinaShenzhen 518110China Department of Engineering Mechanics School of Civil EngineeringWuhan UniversityWuhan 430072China State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China

One-dimensional(1D)nanomaterials easily bend due to perturbations from their surroundings or their own *** phenomenon not only impacts the performances of various devices but has also been employed to develop a variety of new functional devices,in which the bending energies of the nanomaterials determine the device ***,measuring the energies of such nanomaterials is extremely ***,pseudo-break imaging of 1D nanomaterials has been proposed and realized on individual carbon nanotubes(CNTs),in which a CNT appears to break and has a fracture but is actually *** imaging approach provides the values of the bending energies of the CNTs with an accuracy of 1–50 ***,this imaging approach can manipulate the bending shapes and energies of *** work presents a protocol for bending analysis and manipulation,which are vital to fundamental and applied studies of 1D nanomaterials.

关键词： pseudo-break imaging carbon nanotube electron microscopy elastic bending energy