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Weight change and all-cause and cause-specific mortality:A 25-year follow-up study

Chinese Medical Journal 2024年第10期137卷 1169-1178页

作者： Huan Yang Jianbing wang Xiaokun wang Wanyi Sun Chenyunhao Tong Jinhu Fan Youlin qiao Christian *** Department of Cancer Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Public Health Zhejiang University School of MedicineNational Clinical Research Center for Children’s HealthHangzhouZhejiang 310058China Metabolic Epidemiology Branch Division of Cancer Epidemiology and GeneticsNational Cancer InstituteRockvilleMD 20850USA

Background:Whether the dynamic weight change is an independent risk factor for mortality remains *** study aimed to examine the association between weight change and risk of all-cause and cause-specific mortality based on the Linxian Nutrition Intervention Trial(NIT)***:Body weight of 21,028 healthy residents of Linxian,Henan province,aged 40-69 years was measured two times from 1986 to *** events were prospectively collected up to *** maintenance group(weight change<2 kg)or stable normal weight group was treated as the *** proportional hazard model was performed to calculate hazard ratios(HRs)and 95%confidence intervals(95%CIs)to estimate the risk of ***:A total of 21,028 subjects were included in the final *** with the weight maintenance group,subjects with weight loss≥2 kg had an increased risk of death from all-cause(HR_(All-cause)=1.14,95%CI:1.09-1.19,P<0.001),cancer(HR_(Cancer)=1.12,95%CI:1.03-1.21,P=0.009),and heart disease(HR_(Heart diseases)=1.21,95%CI:1.11-1.31,P<0.001),whereas subjects with weight gain≥5 kg had 11%(HR_(Cancer)=0.89,95%CI:0.79-0.99,P=0.033)lower risk of cancer mortality and 23%higher risk of stroke mortality(HR_(Stroke)=1.23,95%CI:1.12-1.34,P<0.001).For the change of weight status,both going from overweight to normal weight and becoming underweight within 5 years could increase the risk of total death(HR_(Overweight to normal)=1.18,95%CI:1.09-1.27;HR_(Becoming underweight)=1.35,95%CI:1.25-1.46)and cancer death(HR_(Overweight to normal)=1.20,95%CI:1.04-1.39;HR_(Becoming underweight)=1.44,95%CI:1.24-1.67),while stable overweight could increase the risk of total death(HR_(Stable overweight)=1.11,95%CI:1.05-1.17)and death from stroke(HR_(Stable overweight)=1.44,95%CI:1.33-1.56).Interaction effects were observed between age and weight change on cancer mortality,as well as between baseline BMI and weight change on all-cause,heart disease,and stroke mortality(all P_(

关键词： Weight change All-cause mortality Cancer Stroke Heart diseases Body mass index

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Finite Element Method Simulation of Wellbore Stability under Different Operating and Geomechanical Conditions

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Fluid Dynamics & Materials Processing 2024年第1期20卷 205-218页

作者： Junyan Liu Ju Liu Yan wang Shuang Liu qiao wang Yihe Du Oil&Gas Project Research Institute PetroChina Tarim Oilfield CompanyKorla841000China Petroleum Engineering School Southwest Petroleum UniversityChengdu610500China

The variation of the principal stress of formations with the working and geo-mechanical conditions can trigger wellbore instabilities and adversely affect the well completion.A finite element model,based on the theory of poro-elasticity and the Mohr-Coulomb rock damage criterion,is used here to analyze such a *** changes in wellbore stability before and after reservoir acidification are simulated for different pressure *** results indicate that the risk of wellbore instability grows with an increase in the production-pressure difference regardless of whether acidification is completed or not;the same is true for the instability *** acidizing,the changes in the main geomechanical parameters(i.e.,elastic modulus,Poisson’s ratio,and rock strength)cause the maximum wellbore instability coefficient to increase.

关键词： Wellbore stability finite element acidizing operation well completion

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Nano-silica modified lightweight and high-toughness carbon fiber/phenolic ablator with excellent thermal insulation and ablation performance

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Defence Technology（防务技术） 2024年第1期31卷 192-199页

作者： Wenjie Xu Wenda Song Xianfeng Jia Cheng Ma Jitong wang Wenming qiao Licheng Ling State Key Laboratory of Chemical Engineering East China University of Science and TechnologyShanghai 200237China School of Chemical Engineering and Materials Changzhou Institute of TechnologyChangzhou 213032China Key Laboratory of Specially Functional Polymeric Materials and Related Technology(Ministry of Education) School of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

Lightweight and high-toughness carbon fiber/phenolic ablator(CFPA)is required as the Thermal Protection System(TPS)material of aerospace vehicles for next-generation space *** improve the ablative properties,silica sol with good particle size distribution prepared using tetramethoxysilane(TMOS)was blended with natural rubber latex and deposited onto carbon fiber felt,which was then integrated with phenolic aerogel matrix,introducing nano-silica into the framework of *** modified CFPA with a low density of 0.28—0.31 g/cm3exhibits strain-in-fracture as high as 31.2%and thermal conductivity as low as 0.054 W/(m·K).Furthermore,a trace amount of nano-silica could effectively protect CFPA from erosion of oxidizing atmosphere in different high-temperature *** oxyacetylene ablation test of 3000°C for 20 s shows a mass ablation rate of 0.0225 g/s,a linear ablation rate of 0.209 mm/s for the modified CFPA,which are 9.64%and 24.82%lower than the unmodified ***,the long-time butane ablation test of 1200°C for 200 s shows an insignificant recession with mass and linear ablation rate of 0.079 g/s and 0.039 mm/s,16.84%and 13.33%lower than the unmodified ***,the fixed thermocouple in the test also demonstrates a good thermal insulation performance with a low peak back-face temperature of 207.7°C,12.25%lower than the unmodified ***,the nano-silica modified CFPA with excellent overall performance presents promising prospects in high-temperature aerospace applications.

关键词： Nano-silica Carbonfiber Phenolic aerogel Insulation Ablation

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Impact of Initial Soil Conditions on Soil Hydrothermal and Surface Energy Fluxes in the Permafrost Region of the Tibetan Plateau

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Advances in Atmospheric Sciences 2024年第4期41卷 717-736页

作者： Siqiong LUO Zihang CHEN jingyuan wang Tonghua WU Yao XIAO Yongping qiao Key Laboratory of Land Surface Process and Climate Change in Cold and Arid Regions Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Cryosphere Research Station on the Qinghai-Tibet Plateau State Key Laboratory of Cryospheric ScienceNorthwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China

Accurate initial soil conditions play a crucial role in simulating soil hydrothermal and surface energy fluxes in land surface process *** study emphasized the influence of the initial soil temperature(ST)and soil moisture(SM)conditions on a land surface energy and water simulation in the permafrost region in the Tibetan Plateau(TP)using the Community Land Model version 5.0(CLM5.0).The results indicate that the default initial schemes for ST and SM in CLM5.0 were simplistic,and inaccurately represented the soil characteristics of permafrost in the TP which led to underestimating ST during the freezing period while overestimating ST and underestimating SLW during the thawing period at the XDT *** the long-term spin-up method to obtain initial soil conditions has only led to limited improvement in simulating soil hydrothermal and surface energy *** modified initial soil schemes proposed in this study comprehensively incorporate the characteristics of permafrost,which coexists with soil liquid water(SLW),and soil ice(SI)when the ST is below freezing temperature,effectively enhancing the accuracy of the simulated soil hydrothermal and surface energy ***,the modified initial soil schemes greatly improved upon the results achieved through the long-term spin-up *** modified initial soil schemes experiments resulted in a 64%,88%,and 77%reduction in the average mean bias error(MBE)of ST,and a 13%,21%,and 19%reduction in the average root-mean-square error(RMSE)of SLW compared to the default simulation ***,the average MBE of net radiation was reduced by 7%,22%,and 21%.

关键词： initial soil conditions soil temperature soil liquid water soil ice surface energy fluxes permafrost

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Mechanism of nanoparticle aggregation in gas-liquid microfluidic mixing

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Chinese Chemical Letters 2024年第4期35卷 376-381页

作者： Hongxia Li Xiyang wang Du qiao Jiahao Li Weiping Zhu Honglin Li Key Laboratory for Precision&Non-traditional Machining Technology of Ministry of Education Dalian University of TechnologyDalian 116023China Shanghai Key Laboratory of New Drug Design School of PharmacyEast China University of Science and TechnologyShanghai 200237China

Using gas-liquid segmented micromixers to prepare nanoparticles that have a homogeneous particle size, controllable shape, and monodispersity advantages. Although nanoparticle aggregation within a microfluid has been shown to be affected by the shear effect, the shear effect triggering conditions in gasliquid two-phase flow is unclear and the aggregation behavior of nanoparticles under the shear effect is difficult to predict, resulting in uncontrollable physical and chemical properties of nanoparticle aggregates. In this study, a numerical simulation of nanoparticle aggregation in gas-liquid two-phase flow under the shear effect is performed using the CFD-DEM method. Then, the effects of total flow rate,gas-liquid two-phase flow ratio, and particle volume fraction on particle aggregation were analyzed to achieve control of particle aggregation shape and size. Meanwhile, the triggering mechanism of the shear effect and the mechanism of the shear effect on the aggregation of nanoparticles were clarified. The results show that increasing the total flow rate or decreasing the gas-liquid two-phase flow rate ratio can induce the shear effect, which reduces the particle aggregation size and makes the morphology tend to be spherical. Moreover, increasing the particle volume fraction, and total flow rate or decreasing the gas-liquid two-phase flow rate ratio also increases the number of particle collisions and induce interparticle adhesion. Hence, particle adhesion and the shear effect compete with each other and together affect particle aggregation.

关键词： Microfluidic Gas-liquid segmented micromixer Nanoparticle aggregation Shear effect Numerical calculation

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Emerging roles of exosomes in oral diseases progression

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International Journal of Oral Science 2024年第1期16卷 36-51页

作者： Jiayi wang Junjun jing Chenchen Zhou Yi Fan State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Cariology and Endodontics West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Pediatric Dentistry West China Hospital of StomatologySichuan UniversityChengduChina

Oral diseases, such as periodontitis, salivary gland diseases, and oral cancers, significantly challenge health conditions due to their detrimental effects on patient's digestive functions, pronunciation, and esthetic demands. Delayed diagnosis and non-targeted treatment profoundly influence patients' prognosis and quality of life. The exploration of innovative approaches for early detection and precise treatment represents a promising frontier in oral medicine.

关键词： diseases diagnosis salivary

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Enhancing CO_(2)capture of an aminoethylethanolamine-based non-aqueous absorbent by using tertiary amine as a proton-transfer mediator:From performance to mechanism

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Journal of Environmental Sciences 2024年第6期140卷 146-156页

作者： Xiaobin Zhou Danwang Chao Liu Guohua jing Bihong Lv Dunqiu wang College of Environmental Science and Engineering Guilin University of TechnologyGuilin 541004China The Guangxi Key Laboratory of Theory and Technology for Environmental Pollution Control Guilin University of TechnologyGuilin 541004China College of Chemical Engineering Huaqiao UniversityXiamen 361021China

Non-aqueous absorbents(NAAs)have attracted increasing attention for CO_(2)capture because of their great energy-saving *** diamines which can provide high CO_(2)absorption loading are promising candidates for formulating NAAs but suffer disadvantages in *** this study,a promising strategy that using tertiary amines(TAs)as proton-transfer mediators was proposed to enhance the regenerability of an aminoethylethanolamine(AEEA,diamine)/dimethyl sulfoxide(DMSO)(A/D)***,some employed TAs such as N,N-diethylaminoethanol(DEEA),N,N,N’,N’’,N’’-pentamethyldiethylenetriamine(PMDETA),3-dimethylamino-1-propanol(3DMA1P),and N,N-dimethylethanolamine(DMEA)enhanced not only the regenerability of the A/D NAA but also the CO_(2)absorption ***,the CO_(2)absorption loading and cyclic loading were increased by about 12.7%and 15.5%-22.7%,*** TA-enhanced CO_(2)capture mechanism was comprehensively explored via nuclear magnetic resonance technique and quantum chemical *** CO_(2)absorption,the TA acted as an ultimate proton acceptor for AEEA-zwitterion and enabled more AEEA to form carbamate species(AEEACOO-)to store CO_(2),thus enhancing CO_(2)*** CO_(2)desorption,the TA first provided protons directly to AEEACOO-as a proton donor;moreover,it functioned as a proton carrier and facilitated the low-energy step-wise proton transfer from protonated AEEA to AEEACOO-.Consequently,the presence of TA made it easier for AEEACOO-to obtain protons to decompose,resulting in enhanced CO_(2)*** a word,introducing the TA as a proton-transfer mediator into the A/D NAA enhanced both the CO_(2)absorption performance and the regenerability,which was an efficient way to“kill two birds with one stone”.

关键词： Carbon dioxide capture Non-aqueous absorbent Tertiary amine Proton-transfer mediator Enhanced mechanism

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A CSMA/CA based MAC protocol for hybrid Power-line/Visible-light communication networks:Design and analysis

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Digital Communications and Networks 2024年第2期10卷 481-497页

作者： Sheng Hao Huyin Zhang Fei Yang Chenghao Li jing wang School of Computer Science Central China Normal UniversityWuhan430079PR China Hubei Key Laboratory of intelligent Robot(Wuhan Institute of Technology) Wuhan430079PR China School of Computer Science Wuhan UniversityWuhan430079China School of Information Science and Engineering Shandong Normal UniversityJinan250000China School of Computer Science Hubei University of TechnologyWuhan430079China

Hybrid Power-line/Visible-light Communication(HPVC)network has been one of the most promising Cooperative Communication(CC)technologies for constructing Smart Home due to its superior communication reliability and hardware *** research on HPVC networks focuses on the performance analysis and optimization of the Physical(PHY)layer,where the Power Line Communication(PLC)component only serves as the backbone to provide power to light Emitting Diode(LED)*** designing a Media Access Control(MAC)protocol remains a great challenge because it allows both PLC and Visible Light Communication(VLC)components to operate data transmission,i.e.,to achieve a true HPVC network *** solve this problem,we propose a new HPC network MAC protocol(HPVC MAC)based on Carrier Sense Multiple Access/Collision Avoidance(CSMA/CA)by combining IEEE 802.15.7 and IEEE 1901 ***,we add an Additional Assistance(AA)layer to provide the channel selection strategies for sensor stations,so that they can complete data transmission on the selected channel via the specified CSMA/CA mechanism,*** on this,we give a detailed working principle of the HPVC MAC,followed by the construction of a joint analytical model for mathematicalmathematical validation of the HPVC *** the modeling process,the impacts of PHY layer settings(including channel fading types and additive noise feature),CSMA/CA mechanisms of 802.15.7 and 1901,and practical configurations(such as traffic rate,transit buffer size)are comprehensively taken into ***,we prove the proposed analytical model has the ***,through extensive simulations,we characterize the HPVC MAC performance under different system parameters and verify the correctness of the corresponding analytical model with an average error rate of 4.62%between the simulation and analytical results.

关键词： Hybrid power-line/Visible light communication (HPVC)networks MAC protocol CSMA/CA IEEE 802.15.7 IEEE 1901 Performance analysis

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Investigation of Maxima Assumptions in Modelling Tropical Cyclone- Induced Hazards in the South China Sea

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China Ocean Engineering 2024年第3期38卷 491-504页

作者： WEN Ze-guo wang Fu-ming WAN jing YANG Fan School of Civil Engineering Sun Yat-sen University&Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Guangdong Academy of Safety Science and Technology Guangzhou 510060China Guangdong Key Laboratory of Oceanic Civil Engineering Guangzhou 510275China Advanced Energy Science and Technology Guangdong Laboratory(Yangjiang Offshore Wind Energy Laboratory) Yangjiang 529500China

The present study aims to examine the suitability of two commonly used assumptions that simplify modelling metoceanconditions for designing offshore wind turbines in the South China Sea (SCS). The first assumption assumes thatjoint N-year extreme wind and wave events can be independently estimated and subsequently combined. The secondone assumes peak wind and waves can be modelled as occurring simultaneously during a tropical cyclone (TC) *** better understand the potential TC activity, a set of 10000 years synthetic TC events are generated. The wind fieldmodel and the Mike 21 spectral wave model are employed to model the TC-induced hazards. Subsequently, theeffect of the assumptions is evaluated by analyzing the peak structural response of both monopile and semisubmersibleoffshore wind turbines during TC events. The results demonstrate that the examined assumptions are generally *** assessing the implications of these assumptions, valuable insights are obtained, which can inform andimprove the modelling of TC-induced hazards in the SCS region.

关键词： tropical cyclone numerical wave modelling hazards offshore wind turbines structural response

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Analog spatiotemporal feature extraction for cognitive radio-frequency sensing with integrated photonics

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Light(Science & Applications) 2024年第3期13卷 478-487页

作者： Shaofu Xu Binshuo Liu Sicheng Yi jing wang Weiwen Zou State Key Laboratory of Advanced Optical Communication Systems and Networks Intelligent Microwave Lightwave Integration Innovation Center(imLic)Department of Electronic EngineeringShanghai Jiao Tong UniversityShanghaiChina

Analog feature extraction(AFE)is an appealing strategy for low-latency and efficient cognitive sensing systems since key features are much sparser than the Nyquist-sampled ***,applying AFE to broadband radio-frequency(RF)scenarios is challenging due to the bandwidth and programmability bottlenecks of analog electronic ***,we introduce a photonics-based scheme that extracts spatiotemporal features from broadband RF signals in the analog *** feature extractor structure inspired by convolutional neural networks is implemented on integrated photonic circuits to process RF signals from multiple antennas,extracting valid features from both temporal and spatial *** of the tunability of the photonic devices,the photonic spatiotemporal feature extractor is trainable,which enhances the validity of the extracted ***,a digital-analog-hybrid transfer learning method is proposed for the effective and low-cost training of the photonic feature *** validate our scheme,we demonstrate a radar target recognition task with a 4-GHz instantaneous *** results indicate that the photonic analog feature extractor tackles broadband RF signals and reduces the sampling rate of analog-to-digital converters to 1/4 of the Nyquist sampling while maintaining a high target recognition accuracy of 97.5%.Our scheme offers a promising path for exploiting the AFE strategy in the realm of cognitive RF sensing,with the potential to contribute to the efficient signal processing involved in applications such as autonomous driving,robotics,and smart factories.

关键词： scheme driving smart

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