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数字底座平台在公路工程设计评审中的应用

公路 2024年第7期69卷 199-203页

作者：黄河清卢靖宇中交第二公路勘察设计研究院有限公司武汉市430056 广东湾区交通建设投资有限公司广州市510699

“云看线”是数字底座平台技术在公路工程设计评审中的实现方式,通过数字化底座平台(或称云平台)技术实现对特定环境与工程对象的多维度观察和讲解,具有多样化的信息表达方式和更全面的看线内容,是对传统方案汇报和现场看线方式的重构,... 详细信息

“云看线”是数字底座平台技术在公路工程设计评审中的实现方式,通过数字化底座平台(或称云平台)技术实现对特定环境与工程对象的多维度观察和讲解,具有多样化的信息表达方式和更全面的看线内容,是对传统方案汇报和现场看线方式的重构,其风险更加可控,参与人数和地域无限制。在回顾公路工程设计评审传统汇报、看线方式局限的基础上,对实现“云看线”所需的材料和方法进行了分析,提出了相关技术指标。在狮子洋通道项目初步设计评审会上进行了应用实践,验证了“云看线”材料和方法的各项技术指标。

关键词：狮子洋通道设计评审数字化平台云看线 BIM+GIS

不稳定心绞痛老年住院患者经皮冠状动脉介入术后生活质量影响因素研究

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中国健康教育 2024年第2期40卷 182-186,191页

作者：张丽萍丁雯陆静钰孙吉孙芳哈琳宁夏医科大学总医院宁夏银川750001

目的分析影响不稳定心绞痛(Unstable Angina,UA)老年住院患者经皮冠状动脉介入术(Percutaneous Coronary Intervention,PCI)后生活质量的影响因素。方法采用方便抽样方法选取部分UA老年住院患者进行调查。采用多元线性回归模型分析影响U... 详细信息

目的分析影响不稳定心绞痛(Unstable Angina,UA)老年住院患者经皮冠状动脉介入术(Percutaneous Coronary Intervention,PCI)后生活质量的影响因素。方法采用方便抽样方法选取部分UA老年住院患者进行调查。采用多元线性回归模型分析影响UA老年住院患者PCI术后生活质量的主要因素,采用方差分析、Pearson相关分析法分析其生活质量得分与健康素养各项得分间的关系。结果UA老年住院患者PCI术后生活质量平均得分为(103.76±14.38)分。多元线性回归分析结果显示,年龄>79岁(β=5.829)、初中及以下文化程度(β=5.264)、家庭人均月收入<3000元(β=4.064)、非医保付费方式(β=7.103)、无运动训练(β=6.182)、未规律服药(β=8.176)是影响UA老年住院患者PCI术后生活质量的主要因素(P<0.05)。方差分析结果显示,UA老年住院患者的信息获取能力、交流互动能力、改善健康意愿、经济支持意愿得分均随其生活质量评分降低而降低(P<0.05)。Pearson相关分析结果显示,UA老年住院患者信息获取能力、交流互动能力、改善健康意愿、经济支持意愿各维度得分均与其生活质量评分呈正相关(P<0.05)。结论影响UA老年住院患者PCI术后生活质量的因素较多,且生活质量与其健康素养各项得分均呈正相关。

关键词：老年不稳定心绞痛经皮冠状动脉介入术生活质量影响因素

TWO new rotenoids from the root of Derris elliptica

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Chinese Chemical Letters 2008年第10期19卷 1218-1220页

作者： Hai Ying lu jing yu Liang Ping yu Wei Qu Ling Zhao Department of Natural Medicinal Chemistry China Pharmaceutical University Nanjing 210009 PR China

Two new rotenoids 4＇,5＇-dihydroxy-6a,12a-dehydrodeguelin （1）,11.4t,5＇-tdhydroxy-6a,12a-dehydrodeguelin （2）, along with two known rotenoids rotenone and deguelin were isolated from the root of Derris elliptica c... 详细信息

关键词： Derris elliptica Rotenoid

Intracranial infection and sepsis in infants caused by Salmonella derby:A case report

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世界临床病例杂志 2023年第28期11卷 6961-6966页

作者： jing-lu yu Li-Li Jiang Rong Dong Si-yu Liu Department of Clinical Laboratory The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Neonatology The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND Salmonella derby(***)is a Gram-negative diplococcus that is common in the digestive *** patients generally experience symptoms such as fever and *** cases are mostly self-healing gastroenteritis,and severe cases can cause fatal typhoid *** cases are more common in *** most common form of *** infection is self-healing gastroenteritis,in which,fever lasts for about 2 d and diarrhea forluid(CSF)culture was positive for Gram-negative bacilli,which conformed to *** treatment with meropenem and ceftriaxone antibiotics,the patient was discharged home in a clinically stable state after 4 wk of *** We reported a rare case of *** cultured in *** enters the CSF through the blood–brain barrier,causing purulent *** not treated timeously,it can lead to serious,life-threatening infection.

关键词： Salmonella derby Infants Cerebrospinal fluid Case report

Advancement in porphyrin/phthalocyanine compounds-based perovskite solar cells

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Tough Poly(L-DOPA)-containing Double Network Hydrogel Beads with High Capacity of Dye Adsorption

结构化学 2024年第3期43卷 55-66页

作者： Chen lu Zefeng yu jing Cao State Key Laboratory of Applied Organic Chemistry Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu ProvinceCollege of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou730000PR China

Porphyrin and phthalocyanine compounds belong to a class of large and aromatic macrocyclic *** to their unique structures and electronic properties,they have found widespread applications in optoelectronic *** recent years,the doping of porphyrins and phthalocyanines into perovskite solar cells(PSCs)has emerged as an effective strategy to enhance device performance and *** doping strategy enables the modulation of perovskite film crystallization and surface defects,thereby improving charge transfer and enhancing the photo-conversion *** sensitizers,porphyrins and phthalocyanines absorb light in the visible and near-infrared spectral ranges,providing an advantage to the light absorption characteristics of ***,their roles in interface modification and defect repair contribute to the long-term stability of the *** central metal of porphyrin can also adsorb ions and prevent the migration of harmful *** review summarizes the recent progress in the research on porphyrin and phthalocyanine-doped PSCs,empha-sizing their potential value in enhancing optoelectronic performance,increasing stability and expanding the application scope of these devices.

关键词： Porphyrin Phthalocyanine Charge transport Interfacial chemistry Perovskite solar cells

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Chinese Journal of Polymer Science 2018年第11期36卷 1251-1261页

作者： Pei-Bin Zhang An-Qi Tang Zhang-Hui Wang jing-yu lu Bao-Ku Zhu Li-Ping Zhu Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering Zhejiang University

Developing a low-cost and well-recyclable adsorbent with high adsorption capacity is greatly desirable in dye wastewater treatment. Here, we demonstrate a kind of novel tough and reusable hydrogel beads with quite high capacity of dye adsorption via incorporating mussel-bioinspired poly（L-DOPA）（PDOPA） into alginate/poly（acrylamide） double network （DN） hydrogels. The synthesized PDOPA nanoaggregates were introduced into the DN hydrogels by simple one-pot mixing with the monomers prior to polymerization. The fabricated hydrogel beads exhibited high mechanical strength and good elastic recovery due to the interpenetrating Ca2＋-alginate and poly（acrylamide） networks. It was shown that the beads exhibited relatively high dye adsorption capacity compared to other adsorbents reported in literature, and the introduction of PDOPA with an appropriate amount raised the adsorption capacity. It is believed that the addition of PDOPA and the matrix of double network architecture contributed synergistically to the high adsorption capacity of hydrogel beads. Moreover, the desorption of dyes could be easily realized via rinsing in acidic water and ethanol solution. The hydrogel beads remained the high adsorption capacity even after 5 times of adsorption and desorption cycles. This tough and stable hydrogel with high adsorption capacity may have potential in treatment of dye wastewater released by textile dyeing industry.

关键词： Dye adsorption Hydrogel beads Poly(L-DOPA) Double network High strength

The role of exosomes in adult neurogenesis:implications for neurodegenerative diseases

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Neural Regeneration Research 2024年第2期19卷 282-288页

作者： Zhuoyang yu Yan Teng jing Yang lu Yang Institute of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Laboratory of Aging Research School of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina

Exosomes are cup-shaped extracellular vesicles with a lipid bilayer that is approximately 30 to 200 nm in *** are widely distributed in a range of body fluids,including urine,blood,milk,and *** exert biological function by transporting factors between different cells and by regulating biological pathways in recipient *** an important form of intercellular communication,exosomes are increasingly being investigated due to their ability to transfer bioactive molecules such as lipids,proteins,mRNAs,and microRNAs between cells,and because they can regulate physiological and pathological processes in the central nervous *** neurogenesis is a multistage process by which new neurons are generated and migrate to be integrated into existing neuronal *** the adult brain,neurogenesis is mainly localized in two specialized niches:the subventricular zone adjacent to the lateral ventricles and the subgranular zone of the dentate *** increasing body of evidence indicates that adult neurogenesis is tightly controlled by environmental conditions with the *** recent studies,exosomes released from different sources of cells were shown to play an active role in regulating neurogenesis both in vitro and in vivo,thereby participating in the progression of neurodegenerative disorders in patients and in various disease ***,we provide a state-of-the-art synopsis of existing research that aimed to identify the diverse components of exosome cargoes and elucidate the therapeutic potential of exosomal contents in the regulation of neurogenesis in several neurodegenerative *** emphasize that exosomal cargoes could serve as a potential biomarker to monitor functional neurogenesis in *** addition,exosomes can also be considered as a novel therapeutic approach to treat various neurodegenerative disorders by improving endogenous neurogenesis to mitigate neuronal loss in the central nervous system.

关键词： adult neurogenesis Alzheimer’s disease amyotrophic lateral sclerosis exosome Huntington’s disease neurodegenerative disease neurogenic niches Parkinson’s disease

Apparent diffusion coefficient-based histogram analysis differentiates histological subtypes of periampullary adenocarcinoma

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World Journal of Gastroenterology 2019年第40期25卷 6116-6128页

作者： jing-yu lu Hao yu Xian-lun Zou Zhen Li Xue-Mei Hu Ya-Qi Shen Dao-yu Hu Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina Department of Radiology the First Affiliated Hospital of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina

BACKGROUND For periampullary adenocarcinoma,the histological subtype is a better prognostic predictor than the site of tumor ***-type periampullary adenocarcinoma(IPAC)is reported to have a better prognosis than the pancreatobiliary-type periampullary adenocarcinoma(PPAC).However,the classification of histological subtypes is difficult to determine before *** diffusion coefficient(ADC)histogram analysis is a noninvasive,nonenhanced method with high reproducibility that could help differentiate the two *** To investigate whether volumetric ADC histogram analysis is helpful for distinguishing IPAC from *** Between January 2015 and October 2018,476 consecutive patients who were suspected of having a periampullary tumor and underwent magnetic resonance imaging(MRI)were reviewed in this retrospective *** patients who underwent MRI at 3.0 T with different diffusion-weighted images(b-values=800 and 1000 s/mm^2)and who were confirmed with a periampullary adenocarcinoma were further ***,the mean,5th,10th,25th,50th,75th,90th,and 95th percentiles of ADC values and ADCmin,ADCmax,kurtosis,skewness,and entropy were obtained from the volumetric histogram *** were made by an independent Student's t-test or Mann-Whitney U ***-class receiver operating characteristic curve analysis was performed to determine and compare the diagnostic value of each significant *** In total,40 patients with histopathologically confirmed IPAC(n=17)or PPAC(n=23)were *** mean,5th,25th,50th,75th,90th,and 95th percentiles and ADCmax derived from ADC1000 were significantly lower in the PPAC group than in the IPAC group(Plues derived from ADC800 showed no significant difference between the two *** 75th percentile of ADC1000 values achieved the highest area under the curve(AUC)for differentiating IPAC from PPAC(AUC=0.781;sensitivity,91%;specificity,59%;cut-off value,1.50×10^-3

关键词： Periampullary adenocarcinoma Apparent diffusion coefficient Histogram analysis Histopathology Differential diagnosis

Capturing and visualizing the phase transition mediated thermal stress of thermal barrier coating materials via a cross-scale integrated computational approach

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Journal of Advanced Ceramics 2024年第4期13卷 413-428页

作者： Mengdi Gan Tianlong lu Wei yu jing Feng Xiaoyu Chong Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China

The generation and evaluation of severely high thermal stress(σ)is known to be responsible for failure of thermal barrier coatings(TBCs)during thermal *** is crucial and challenging to capture fluctuations inσcaused by the phase transition,which has motivated us to develop a high-throughput multiscale evaluation method forσin TBCs that considers the phase transition of the top ceramic materials by coupling first-principles calculations with finite element *** method quantitatively evaluates and visualizesσof the real TBC structure under thermal cycling by multifield ***,the thermophysical properties calculated by the first-principles calculations consider the effects of temperature and phase transition,which not only reduces the cost of obtaining data but also has a more physical *** this work,rare earth tantalites(RETaO_(4))are introduced as ceramic layers,and the results demonstrate thatσundergoes a rapid escalation near the phase transition temperature(T_(t)),particularly in the TBCs_GdTaO_(4) system,where it rises from 224 to 435 *** discontinuity inσmay originate from the significant alterations in Young’s modulus(increase by 27%–78%)and thermal conductivity(increase by 53%–146%)near T_(t).The TBCs_NdTaO_(4) and TBCs_SmTaO_(4) systems exhibit noteworthy temperature drop gradients and minimalσfluctuations,which are beneficial for extending service lifetime of *** approach facilitates the prediction of failure mechanisms and provides theoretical guidance for the reverse design of TBC materials to obtain low thermal stress systems.

关键词： thermal conductivity first-principles calculations thermodynamics thermal stress thermophysical properties