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Intragastric fish bones migrate into the liver:A case report

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World Journal of Clinical Cases 2023年第14期11卷 3256-3260页

作者： Mu-Gen Dai jing-jing zheng Jie Yang Bin Ye Department of Gastroenterology The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Gastrointestinal Surgery The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Infectious Disease The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND A foreign body in the digestive tract is a common disease in the ***,it is rare for a foreign body to migrate into the *** patients are diagnosed before or after perforation of the digestive *** removal of intrahepatic foreign bodies is an effective treatment *** SUMMARY A 55-year-old male patient was admitted to the hospital due to fever for 3 d,in addition to pain and discomfort in the right side of his *** admission,abdominal computed tomography showed a foreign body in the liver,and gastroscopy did not indicate obvious erosion or *** patient then underwent laparoscopic *** the operation,an abscess was seen near the gastric antrum and between the caudate lobes of the *** was approximately 30 mm×31 mm×23 mm in *** abscess was cut open,and a fish bone was found *** fish bone had penetrated the liver and was successfully *** was confirmed that the fish bone migrated from the stomach to the *** Although intrahepatic foreign bodies are rare,they should be diagnosed and treated as early as possible to avoid serious complications such as intrahepatic abscess,which may lead to liver resection and even life-threatening events.

关键词： Foreign body Intrahepatic Migrate Stomach Case report

Thermal effects on structure and photoluminescence properties of diamond-like carbon films prepared by pulsed laser deposition

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Optoelectronics Letters 2006年第3期2卷 182-185页

作者： CHEN Da LI Qing-shan WANG jing-jing zheng Xue-gang College of Physics and Engineering Qufu Normal University Qufu 273165 China

Un-hydrogenated Diamond-like Carbon （DLC） films were prepared by pulsed laser deposition technique at different substrate temperature. The Raman spectra, the absorption and the photoluminescence spectra were measured. The dependence of structure and phetoluminescence properties on deposition temperature were studied in detail. The experimental results indicate that the sp^2 sites form small clus ters that consist of both olefinic chains and aromatic ring groups within the sp^3 matrix. With raising deposition temperature,the optical band gaps increase from 1.87 to 2.85 eV. The main band of photoluminescence centered at around 700nm shifts to short wavelength, and the intensity of this band increases. The photoluminescence can be attributed to carrier localization within an increasing sp^2 clusters. It was clarified that the DLC films are ordered with increasing deposition temperature.

关键词：碳薄膜光致发光金刚石脉冲激光沉积作用光谱

Copper-Catalyzed Enantioconvergent Radical C(sp^(3))−N Cross- Coupling to Access Chiral α-Amino-β-lactams

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Precision Chemistry 2023年第10期1卷 576-582页

作者： jing-jing zheng Wei-Long Liu Qiang-Shuai Gu Zhong-Liang Li Ji-Jun Chen Xin-Yuan Liu Shenzhen Key Laboratory of Cross-Coupling Reactions Southern University of Science and TechnologyShenzhen 518055China Shenzhen Grubbs Institute and Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China Academy for Advanced Interdisciplinary Studies and Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China

A copper-catalyzed enantioconvergent radical C-(sp^(3))-N cross-coupling of racemic tertiaryα-bromo-β-lactams with aromatic amines is developed under mild thermal reaction *** use of a sterically demanded oxazoline-derived sulfonamide N,N,N-ligand is crucial for the reaction initiation and effective enantio-discrimination of the azetidinone-derived cyclic alkyl *** strategy provides an attractive approach to access chiralα-amino-β-lactams,an important structural motif in many biologically active *** mechanistic studies support the formation of azetidinone-derived alkyl radicals from the L*Cu(I)-amido complex andα-bromo-β-lactams.

关键词： copper asymmetric radical reactions cross-coupling aromatic amines chiralα-amino-β-lactams

Merging polymers of intrinsic microporosity and porous carbon-based zinc oxide composites in novel mixed matrix membranes for efficient gas separation

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Green Energy & Environment 2025年第1期10卷 203-213页

作者： Muning Chen Jiemei Zhou jing Ma Weigang zheng Guanying Dong Xin Li Zhihong Tian Yatao Zhang jing Wang Yong Wang School of Chemical Engineering Zhengzhou UniversityZhengzhou450001HenanChina State Key Laboratory of Materials-Oriented Chemical Engineering and College of Chemical Engineering Nanjing Tech UniversityNanjing211816JiangsuChina Singapore Membrane Technology Centre Nanyang Environment and Water Research InstituteNanyang Technological UniversitySingapore637141Singapore Engineering Research Center for Nanomaterials Henan UniversityKaifeng475004HenanChina State Key Laboratory of Coking Coal Resources Green Exploitation Zhengzhou UniversityZhengzhou 450001China School of Energy and Environment Southeast UniversityNanjing210096JiangsuChina

Mixed matrix membranes(MMMs)have demonstrated significant promise in energy-intensive gas separations by amalgamating the unique properties of fillers with the facile processability of ***,achieving a simultaneous enhancement of permeability and selectivity remains a formidable challenge,due to the difficulty of achieving an optimal match between polymers and *** this study,we incorporate a porous carbon-based zinc oxide composite(C@ZnO)into high-permeability polymers of intrinsic microporosity(PIMs)to fabricate *** dipole–dipole interaction between C@ZnO and PIMs ensures their exceptional compatibility,mitigating the formation of non-selective voids in the resulting ***,C@ZnO with abundant interconnected pores can provide additional low-resistance pathways for gas transport in *** a result,the CO_(2) permeability of the optimized C@ZnO/PIM-1 MMMs is elevated to 13,215 barrer,while the CO_(2)/N_(2) and CO_(2)/CH4 selectivity reached 21.5 and 14.4,respectively,substantially surpassing the 2008 Robeson upper ***,molecular simulation results further corroborate that the augmented membrane gas selectivity is attributed to the superior CO_(2) affinity of C@*** summary,we believe that this work not only expands the application of MMMs for gas separation but also heralds a paradigm shift in the application of porous carbon materials.

关键词： Mixed matrix membranes Polymers of intrinsic microporosity CO_(2)separation Porous carbon materials

Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui Meng Meina Quan Ling Wang jing Ren Chenguang zheng Jiajia Yang Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Innovation Center for Neurological Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive *** presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s *** use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent *** a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive *** article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound *** is placed on the benefits of introducing these treatment methods and their potential *** found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque *** believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods.

关键词： Alzheimer’s disease blood-brain barrier drugs magnetic resonance imaging-guided focused ultrasound microbubbles scanning ultrasound ultrasound ultrasound stimulation

Oxytocin mediates early experience-dependent crossmodal plasticity in the sensory cortices

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Oxytocin mediates early experience-dependent crossmodal plas...

Comparison of three second-order multivariate methods for the rapid identification and quantitative analysis of tea polyphenols in Chinese teas using HPLC-DAD

中国神经科学学会第十届全国学术会议

作者： Shu-jing Li jing-jing zheng Xiao-Di Zhang Wan-Ying Miao Xiang Yu Institute of Neuroscience and State Key Laboratory of Neuroscience Shanghai Institutes for Biological SciencesChinese Academy of Sciences University of Chinese Academy of Sciences

Objective During the early postnatal period,neural activity,both in the form of spontaneous electrical activity and natural sensory stimulation,is critical to the formation of functional neural *** addition to inducing changes within the target sensory cortex,sensory experience can also crossmodally affect other brain ***,little is known about the synaptic mechanisms underlying these crossmodal changes,especially during the first two weeks of postnatal development,at the peak of ***,we investigate the crossmodal effects of natural sensory experience during the first two postnatal weeks in the sensory *** We used whisker-deprivation,dark-rearing and enriched environment paradigms to increase or reduce neural activity,and examined their effects on synaptic transmission and neuronal excitability in layer 2/3 pyramidal neurons,as well as on the expression of various proteins in the somatosensory and visual *** We found a novel form of plasticity in neonatal mice,where early sensory experience crossmodally regulated development of all sensory ***,unimodal sensory deprivation from birth through whisker-deprivation or dark-rearing reduced excitatory synaptic transmission of layer2/3 pyramidal neurons both in the correspondent sensory cortex,and crossmodally in other sensory *** the other hand,increasing natural sensory experience through environment enrichment significantly increased excitatory synaptic transmission in both somatosensory and visual cortices,and also increased the protein level of post-synaptic proteins GluR2 and *** for changes in gene expression between normal and sensory deprived mice,we found that the mRNA level of the neuropeptide oxytocin secreted from the hypothalamus was significantly reduced in samples from sensory deprived ***,cortical oxytocin protein level was bidirectionally regulated by sensory ***,in vivo application of o

关键词： neural activity synaptic transmission sensory cortices crossmodal plasticity oxytocin

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Comparison of three second-order multivariate methods for th...

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

2019中国化学会第十五届全国计算（机）化学学术会议

作者：张晓华 Qian Zhou Hui-Wen Gu jing-jing zheng Xiang-Dong Qing 许昌学院 Key Laboratory of Biomarker Based Rapid-detection Technology for Food Safety of Henan Province Food and Bioengineering College Xuchang University College of Chemistry and Environmental Engineering Yangtze University Hunan Provincial Key Laboratory of Fine Ceramics and Powder Materials School of Materials and Environmental Engineering Hunan University of Humanities Science and Technology

In actual chromatographic analysis, retention time shifts seriously affect the accuracy of quantitative results of target analytes in complex systems. According to the recent reported references, multivariate curve resolution-alternating least squares(MCR-ALS) has an appealing advantage of possibility of handling multiple data matrices in case of nontrilinear structure, and alternating trilinear decomposition(ATLD) algorithm can also tolerate slight time shifts in HPLC-DAD data and obtain the quantitative results similar to MCR-ALS. Alternating trilinear decomposition-assisted multivariate curve resolution(ATLD-MCR) combines the basic philosophy of the ATLD algorithm and the multivariate curve resolution, which were fully utilized the advantages of ATLD and MCR strategy. In this report, the ability to process second-order chromatographic data with retention time shifts has been investigated through comparing the performances of ATLD, MCR-ALS and ATLD-MCR using the experimental data. In the first place, the validation samples contain five tea polyphenols of three concentrate levels(low, medium and high) within the calibration ranges, help to understand, visualize and interpret these features of these three second-order multivariate methods. Experimental data are also studied concerning the determination of the tea polyphenols in Chinese tea samples by HPLC-DAD. It was found that all three second-order multivariate methods performed well and obtained satisfactory qualitative and quantitative results for the analytes of interest in Pu-Er ripe tea samples and Green tea samples with slight retention time shifts. However, ATLD is disappointing due to the large time shifts for the quantitative analysis of Black tea samples and Clinacanthus nutans tea samples. MCR-ALS and ATLD-MCR have also been found to be useful in this regard, the satisfactory results(average recovery corresponding to MCR-ALS, 86.04-117.60 %, average recovery corresponding to ATLD-MCR, 89.96-115.96%) are

关键词： HPLC-DAD tea polyphenols Alternating trilinear decomposition Multivariate curve resolution Alternating trilinear decomposition-assisted multivariate curve resolution

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Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li jing Xue Yuejia Ma Ke Ye Xue Zhao Fangliang Ge Feifei zheng Lulu Liu Xu Gao Dayong Wang Qing Xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

Regulating crystallization and retarding oxidation in Sn-Pb perovskite via 1D cation engineering for high performance all-perovskite tandem solar cells

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Journal of Energy Chemistry 2025年第1期100卷 646-652页

作者： Ranran Liu Xin zheng Zaiwei Wang Miaomiao Zeng Chunxiang Lan Shaomin Yang Shangzhi Li Awen Wang Min Li jing Guo Xuefei Weng Yaoguang Rong Xiong Li Michael Gr?tzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced Technology Chinese Academy of Sciences School of Physics and Optoelectronic Engineering Hainan University Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO) Chinese Academy of Sciences School of Chemistry Chemical Engineering and Life Sciences State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology

All-perovskite tandem solar cells have the potential to surpass the theoretical efficiency limit of single junction solar cells by reducing thermalization ***,the challenges encompass the oxidation of Sn2+to Sn4+and uncontrolled crystallization kinetics in Sn-Pb perovskites,leading to nonradiative recombination and compositional heterogeneity to decrease photovoltaic efficiency and operational ***,we introduced an ionic liquid additive,1-ethyl-3-methylimidazolium iodide （EMIMI） into Sn-Pb perovskite precursor to form low-dimensional Sn-rich/pure-Sn perovskites at grain boundaries,which mitigates oxidation of Sn2+to Sn4+and regulates the film-forming dynamics of Sn/Pb-based perovskite *** optimized single-junction Sn-Pb perovskite devices incorporating EMIMI achieved a high efficiency of 22.87%.Furthermore,combined with wide-bandgap perovskite sub-cells in tandem device,we demonstrate 2-terminal all-perovskite tandem solar cells with a power conversion efficiency of 28.34%,achieving improved operational stability.

关键词： All-perovskite tandem solar cells Sn-Pb perovskite 1D Regulated crystallization Antioxidation