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Coxsackievirus A6 was the most common enterovirus serotype causing hand,foot,and mouth disease in Shiyan City,central China

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World Journal of Clinical Cases 2022年第31期10卷 11358-11370页

作者： jing-feng li Chuan-Jie Zhang Ya-Wei li Chao li Shi-Chao Zhang Sha-Sha Wang Yong Jiang Xin-Bing Luo Xing-Juan liao Shou-Xin Wu ling lin Department of Pediatrics Taihe HospitalAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Children Health Care Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430061Hubei ProvinceChina Department of Health Services Taihe HospitalAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Pharmaceuticals Shanghai Biotecan Pharmaceuticals Co.Ltd.Shanghai 200000China Zhangjiang Center for Translational Medicine Shanghai Zhangjiang Institute of Medical InnovationShanghai 442000China

BACKGROUND Hand,foot,and mouth disease(HFMD)has become one of the most common infectious diseases in China.Before 2016,the primary causal serotypes were enterovirus A71(EV-A71)and coxsackievirus A16(CV-A16).Following the introduction of EV-A71 vaccines in China since 2016,the situation could change.CV-A6 has recently replaced EV-A71 and CV-A16 in some areas of China.However,the epidemiological characteristics of central China remain unknown.AIM To investigate the clinical symptoms and pathogen spectrum of HFMD in Shiyan City,central China,in recent years.METHODS The epidemiological,clinical,and laboratory data from HFMD cases reported to the Shiyan Center for Disease Control and Prevention between January 2016 and December 2020 were analyzed.196 throat swab specimens were collected from hospitalized HFMD patients between January 2018 and December 2020.To detect and genotype enteroviruses,real-time reverse transcription-polymerase chain reaction and sequencing of the 5'-untranslated region were used.In Shiyan,168 laboratory-confirmed HFMD cases were studied using a logistic regression model to determine the effect of predominant enterovirus serotypes.Based on the logistic regression model,the least absolute shrinkage and selection operator model was used to analyze the correlation between CV-A6 infection and various clinical characteristics in HFMD patients in Shiyan.RESULTS From 2016 to 2020,35840 HFMD cases were reported in Shiyan.The number of cases decreased by 48.4%from 2016 to 2017.Approximately 1.58-fold increases were found in 2018 and 2019 when compared to the previous year,respectively.In 2020,a decrease of about 85.5%was reported when compared to 2019.The most common serotypes shifted from EV-A71 and CV-A16(about 60%-80%in 2016 and 2018)to others(more than 80.0%in 2017,2019,and 2020).EV-A71 lost its dominance in 2017 in Shiyan.Among 196 confirmed HFMD cases,85.7%tested positive for enterovirus,with CV-A6 being the most common serotype(121/168,72.0%).The positive rates for CV-A16 and CVA10 were 4.8%and 3

关键词： Hand,foot,and mouth disease Coxsackievirus A6 Enterovirus Prevalence serotype Fever Myocardial damage

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(K,Na)NbO_(3)-based lead-free piezoceramics:Phase transition,sintering and property enhancement

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Journal of Advanced Ceramics 2012年第1期1卷 24-37页

作者： Ke WANG jing-feng li State Key Laboratory of New Ceramic and Fine Processing Department of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Most widely used piezoelectric ceramics are based on Pb(Zr,Ti)O3(PZT)composition which has adverse environmental and health effects due to its high lead content.Environmental and safety concerns with respect to the utilization,recycling,and disposal of lead-based piezoelectric ceramics have induced a new surge in developing lead-free piezoelectric ceramics.Among all the lead-free ceramics,(K,Na)NbO3(KNN)has drawn increasing attention because of its well-balanced piezoelectric properties and better environmental compatibility.On basis of the author’s work,this review summarizes the progress that has been made in recent years on development of KNN-based piezoelectric ceramics,including crystallographic structure and phase transition analysis,pressurized solid-state sintering as well as liquid-phase-assisted sintering process,and poling treatment for property enhancement.All in all,KNN is a promising lead-free system,but more research is still required both from academic and industrial interests.

关键词： electrical properties ferroelectric properties piezoelectric properties perovskites niobates lead-free

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Bi2Te3-based applied thermoelectric materials:research advances and new challenges

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National Science Review 2020年第12期7卷 1856-1858页

作者： Jun Pei Bowen Cai Hua-Lu Zhuang jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua University

Thermoelectric (TE) materials can directly exchange heat and electricity in the solid state.TE devices that do not contain moving parts or produce emissions have been commercialized as electronic coolers and temperatu... 详细信息

关键词： PERFORMANCE

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Low-cost and environmentally benign selenides as promising thermoelectric materials

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Journal of Materiomics 2018年第4期4卷 304-320页

作者： Tian-Ran Wei Chao-feng Wu Fu li jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of ScienceShanghai200050China Shenzhen Key Laboratory of Advanced Thin Films and Applications College of Physics and EnergyShenzhen UniversityShenzhen518060China Advanced Materials Institute Graduate School at ShenzhenTsinghua UniversityShenzhen518055China

Developing high-efficiency materials with earth-abundant and low-toxicity elements has become a popular trend in the field of thermoelectrics.Among these compounds,oxides and sulfides,the lighter,cheaper and green analogies of tellurides,have been extensively investigated and summarized as well defined classes.Nonetheless,the vast family of selenides with better electrical performance,lower thermal conductivity and higher thermoelectric efficiency have not been specially discussed.Here in this review,we present recent advances in binary and multinary selenide thermoelectric materials,covering traditional PbSe,liquid-like Cu_(2)Se,layered SnSe,diamond-like and disordered multinary compounds.The features of selenides are discussed based on both environmental concerns and from the perspective of chemical bonding,transport properties and performance.Emphasis is put on the“compositionstructure-processing-performance”relationship,and some interesting issues are addressed.Finally,challenges for thermoelectric selenides are discussed,and possible optimization strategies are also suggested.

关键词： Thermoelectric materials Selenides Transport properties

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Practical high-performance lead-free piezoelectrics:structural flexibility beyond utilizing multiphase coexistence

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National Science Review 2020年第2期7卷 355-365页

作者： Qing liu Yichi Zhang jing Gao Zhen Zhou Dong Yang Kai-Yang Lee Andrew Studer Manuel Hinterstein Ke Wang Xiaowen Zhang Longtu li jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University Institute for Applied Materials Karlsruhe Institute of Technology Australian Centre for Neutron Scattering Australian Nuclear Science and Technology Organisation

Due to growing concern for the environment and human health, searching for high-performance lead-free piezoceramics has been a hot topic of scientific and industrial research. Despite the significant progress achieved toward enhancing piezoelectricity, further efforts should be devoted to the synergistic improvement of piezoelectricity and its thermal stability. This study provides new insight into these topics.A new KNN-based lead-free ceramic material is presented, which features a large piezoelectric coefficient(d) exceeding 500 pC/N and a high Curie temperature(T) of ～200℃. The superior piezoelectric response strongly relies on the increased composition-induced structural flexibility due to lattice softening and decreased unit cell distortion. In contrast to piezoelectricity anomalies induced via polymorphic transition, this piezoelectricity enhancement is effective within a broad temperature range rather than a specific small range. In particular, a hierarchical domain architecture composed of nano-sized domains along the submicron domains was detected in this material system, which further contributes to the high piezoelectricity.

关键词： piezoelectricity lead-free potassium–sodium niobite structural flexibility temperature stability

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High thermoelectric figure of merit ZT>1 in SnS polycrystals

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Journal of Materiomics 2020年第1期6卷 77-85页

作者： Asfandiyar Bowen Cai li-Dong Zhao jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China School of Materials Science and Engineering Beihang UniversityBeijing100191China

Eco-friendly tin sulfide(SnS)has attracted increasing attention in the thermoelectric community because of its elemental abundance and analogous crystal structure to SnSe as a new thermoelectric material.However,so far no high dimensionless thermoelectric figure of merit ZT>1 was reported in SnS polycrystals.This work found an effective strategy for enhancing the thermoelectric performance of ptype polycrystalline SnS by Ag doping and vacancy engineering,leading to three orders of magnitude increase in carrier concentration and optimized effective mass and carrier mobility.As a result of the enhanced electrical conductivity,three times higher power factor ~3.85 μW/cm K^(2) at 877 K is realized in Sn_(0.995)Ag_(0.005)S sample.Interestingly,nanostructuring with Ag nano-precipitates were formed in the Agdoped SnS sample.Moreover,with introducing Sn vacancies in the crystal structure of Sn_(0.995-vac)Ag_(0.005)S,the power factor further enhanced to~4.25 μW/cm K^(2).In addition to the low-frequency phonons scattering by Ag nano-precipitates,dislocations strengthens the scattering of mid-frequency phonon,leading to an ultralow lattice thermal conductivity <0.5 W/m K above 800 K and a record high ZT up to 1.1 at 877 K in Sn_(0.99)Ag_(0.005)S polycrystals.

关键词： Thermoelectric tin sulfide Spark plasma sintering Nanoprecipitation Dislocation

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Ferroelectric domains and phase transition of sol-gel processed epitaxial Sm-doped BiFeO_(3)(001)thin films

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Journal of Materiomics 2018年第1期4卷 27-34页

作者： Zhen Zhou Wei Sun Zhenyu liao Shuai Ning jing Zhu jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China National Center for Electron Microscopy in Beijing State Key Laboratory of New Ceramics and Fine ProcessingKey Laboratory of Advanced Materials(MOE)School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

BiFeO_(3),a room-temperature multiferroic material,has recently been increasingly applied as a potential lead-free piezoelectric material due to its large piezoelectricity achieved by doping.In this work,12%Smdoped BiFeO_(3)epitaxial thin films were fabricated on Nb-doped SrTiO_(3)(001)single crystal substrates via sol-gel method.The epitaxy was verified by reciprocal space mapping(RSM)and transmission electron microscope(TEM).The TEM results indicated the coexistence of R3c and Pbam phases in the film.The domains and piezoelectric properties from room temperature to 200℃were characterized by piezoresponse force microscopy(PFM).Domains became active from 110℃to 170℃,and domain configurations changed obviously.A partially fading piezoresponse indicated the emergence of antiferroelectric Pbam.The in-situ domain analysis suggested that the phase transition was accompanied by domain wall motion.Switching spectroscopy PFM(SS-PFM)was further conducted to investigate the piezoresponse during the phase transition.Anomalous responses were found in both ON and OFF states at 170℃,and the film exhibits typical antiferroelectric behavior at 200℃,implying that the completion of phase transition and structure turned to the Pbam phase.This work revealed the origin of the high piezoresponse of Sm-doped BiFeO_(3)thin films at the morphotropic phase boundary(MPB).

关键词： BiFeO_(3) Piezoresponse force microscopy Morphotropic phase boundary Phase transition Antiferroelectric

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B-Site Nanoscale-Ordered Structure Enables Ultra-High Tunable Performance

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Research 2023年第1期2022卷 413-426页

作者： Biaolin Peng Qiuping Lu Yi-Chi Wang jing-feng li Qi Zhang Haitao Huang Laijun liu Chao li limei Zheng Zhong lin Wang ISchool of Advanced Materials and Nanotechnology Xidian UniversityXi'an 710126China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China State Key Laboratory of New Ceramics and Fine Processing Department of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Basque Centre for Materials Applications and NanostructuresUPV/EHU Science ParkBarrio Sarriena s/n48940 LeioaSpain kerbasque Basque Foundation for SciencePlaza Euskadi5Bilbao 48009Spain Department of Applied Physics The Hong Kong Polytechnic UniversityKowloonHong Kong Guangxi Key Laboratory of Optical and Electronic Materials and Devices Guilin University of TechnologyGuilin 541004China Instrument Analysis Center Xi'an Jiaotong UniversityXi'an 710049China 'School of Physics Shandong UniversityJinan 250100China school of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGeorgia 30332-0245USA

Tunable devices constructed by ferroelectric thin flms are often desired to possess a low dielectric loss while maintainging a high dielectric tunability over a broad operating temperature range in applications,for example,resonators,filters,or phase shifters.However,it is dificult to simultaneously achieve these characteristics by traditional strategies,such as doping and strain modifying.Here,we demonstrate that the dielectric tunability of the sol-gel-prepared Pb(Sc_(1/2)Nb_(1/2))_(0.9)(Mg_(1/3)Nb_(2/3))_(0.O3)(PSNMN)thin film can be almost doubled from~47%to~80.0%(at 10kHz)at a low electric field(~530kV/cm),and the dielectric loss can be sharply reduced by more than an order of magnitude,from~0.50 to~0.037(at 1 kHz)when the thin flm was annealed in air at 650℃ for 15h under the help of an atmosphere-compensating-block(ACB)made from the proto-PSNMN gel.Moreover,the PSNMN thin flm annealed with ACB also exhibited an extremely high thermally-stable dielectric tunability in an ultrabroad temperature range(>130 K),which could be attributed to the Maxwell-Wagner(MW)effect generated by the interface between the PSNMN disordered matrix and the B-site nanoscale-ordered structure formed during the long-term annealing process.The reduced dielectric loss is mainly benefited from the reduced concentration of oxygen vacancy and the possibie MW efects,and the enhanced dielectric tunability could be ascribed to the weaker domain-pinning effect by oxygen vacancy.The breakthrough provides a new universal strategy to achieve utrahigh tunable performance in A(B'_(1/2)B"_(1/2))O3 ferroelectric thin films with a B-site nanoscale-ordered structure,meanwhile it paves the way for ultraintergrated tunable thin-flm-devices with great phase shifter performance in practical applications.

关键词： dielectric ferroelectric breakthrough

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Enhanced thermoelectric performance in MnTe due to doping and insitu nanocompositing effects by Ag2S addition

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Journal of Materiomics 2021年第3期7卷 577-584页

作者： Jinfeng Dong Jun Pei Kei Hayashi Wataru Saito Hezhang li Bowen Cai Yuzuru Miyazaki jing-feng li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China Department of Applied Physics Graduate School of EngineeringTohoku UniversitySendai980-8579Japan

Extremely low lattice thermal conductivity is always the pursuit of thermoelectric materials research.In this work,we reported an exceptional effect of Ag2S addition in MnTe,an emerging promising midtemperature thermoelectric material,to enable the realization of minimum lattice thermal conductivity,namely-0.4 Wm^(-1) K^(-1).Such a low lattice thermal conductivity is guaranteed by the incorporation of in-situ formed Ag rich phase(Ag2Te)with ultralow lattice thermal conductivity and further scattering of phonons from the partial doping effects induced point defects and boundaries between various phases.Apart from the dramatically decreased lattice thermal conductivity,the partial doping of Ag and S simultaneously enhance the electrical conductivity,further contributing to enhanced thermoelectric performance.Meanwhile,an inverse sign of Seebeck and Hall coefficient was observed and rationalized by the influence of highly electron-conductive Ag_(2)Te phase.Thanks to the synergetic modulation of electrical and thermal transport properties by in-situ formed composite,a high ZT value of 1.1 was achieved in MnTe based thermoelectric materials,which also demonstrates the importance of compositing approaches to design state-of-the-art thermoelectric materials.

关键词： Manganese telluride Thermoelectric Thermal conductivity Composite

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Cascaded electron transition in CuWO4/CdS/CDs heterostructure accelerating charge separation towards enhanced photocatalytic activity

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Chinese Chemical Letters 2020年第6期31卷 1516-1519页

作者： Yibo Chen jing-feng li Pei-Yu liao Ying-Shan Zeng Zhu Wang Zhao-Qing liu School of Chemistry and Chemical Engineering Guangzhou Key Laboratory for Clean Energy and MaterialsGuangzhou UniversityGuangzhou 510006China

CuWO4,as an n-type oxide semiconductor with a bandgap of 2.2 eV,has stimulated enormous interest as a potential broad-spectrum-active photocatalyst for environmental pollution remediations.However,rapid charge recombination greatly hinders its practical applications.Herein,we present a cascaded electron transition pathway in a ternary heterostructure consisting of CdS quantum dots,carbon dots(CDs)and CuWO4 hollow spheres,which proves to greatly facilitate the photogenerated electron-hole separation,and eventually boosts the degradation efficiency of phenol and congo red by 100%and 46%compared to bare CuWO4.The enhanced performance of the CuWO4/CdS/CDs heterostructure mainly originates from the unidirectional electron migration from CdS to CuWO4 and then to the organics through CDs.This work elucidates the electron transfer kinetics in multi-phase system and provides a new design paradigm for optimizing the properties of CuWO4 based photocatalysts.

关键词： Cascaded electron transition CuWO4 Hollow spheres Carbon dots Photocatalysis

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