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干细胞抗卵巢颗粒细胞衰老的作用机制及进展

中国组织工程研究 2025年第25期29卷 5414-5421页

作者：林美玉赵玺龙高景赵晶阮光萍解放军联勤保障部队第九二〇医院基础医学实验室云南省昆明市650032 干细胞与免疫细胞生物医药技术国家地方联合工程研究中心云南省昆明市650032 云南省细胞治疗技术转化医学重点实验室云南省昆明市650032

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰... 详细信息

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰老的文献,以“干细胞,卵巢颗粒细胞,衰老”为中文检索词,以“stem cells,ovary granulosa cells,aging”为英文检索词,最终纳入67篇文献进行分析。结果与结论:①总结了5种卵巢颗粒细胞衰老的机制:DNA损伤和修复能力下降、氧化应激、线粒体功能受损、炎症反应、激素水平变化;②整理了当前干细胞治疗卵巢颗粒细胞衰老的5种机制:促进增殖和抑制凋亡、分化潜能及再生能力、分泌因子、抗氧化、抗炎症反应和免疫调节;③目前有多种类型的干细胞可通过多种方式协同治疗卵巢颗粒细胞衰老,干细胞疗法在恢复女性生育能力方面具有广阔前景。

关键词：干细胞卵巢颗粒细胞衰老机制氧化应激抑制凋亡细胞因子抗氧化抗炎症反应

Petrochemical wastewater treatment with a pilot-scale bioaugmented biological treatment system

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第11期8卷 1831-1838页

作者： zhao Li-jun MA Fang GUO jing-bo zhao Qing-liang School of Chemical Engineering China University of Petroleum Beijing 102249 China School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China

In solving the deterioration of biological treatment system treating petrochemical wastewater under low temperatures, bioaugmentation technology was adopted by delivering engineering bacteria into a pilot-scale two-stage anoxic-oxic (A/O) process based on previous lab-scale study. Experimental results showed that when the concentrations of COD and NH4+-N of the influent were 370~910 mg/L and 10~70 mg/L, the corresponding average concentrations of those of effluent were about 80 mg/L and 8 mg/L respectively, which was better than the Level I criteria of the Integrated Wastewater Discharge Standard (GB8978-1996). According to GC-MS analysis of the effluents from both the wastewater treatment plant (WWTP) and the pilot system, there were 68 kinds of persistent organic pollutants in the WWTP effluent, while there were only 32 in that of the pilot system. In addition, the amount of the organics in the effluent of the pilot system reduced by almost 50% compared to that of the WWTP. As a whole, after bioaugmentation, the organic removal efficiency of the wastewater treatment system obviously in- creased.

关键词： Bioaugmentation Petrochemical wastewater Pilot-scale study GC/MS

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辽宁沿海油气加工业基地建设研究

聊城师院学报（自然科学版） 1998年第2期11卷 59-63页

作者：姚静肇博聊城师范学院地理系广州教育学院地理系

石油工业是国民经济的支柱产业，在国民经济中占有举足轻重的地位．辽宁沿海地区是重要的石油工业基地．本文论述了其油气加工业的现状。

关键词：油气加工业基地建设辽宁区域规划石油工业

Recurrences for Callan's Generalization of Narayana Polynomials

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Journal of Systems Science & Complexity 2022年第4期35卷 1573-1585页

作者： CHEN Xi YANG Arthur Li bo zhao James jing Yu School of Mathematical Sciences Dalian University of TechnologyDalian116024China Center for Combinatorics LPMCNankai UniversityTianjin300071China School of Mathematics Tianjin UniversityTianjin300350China

By using Chen,Hou and Mu’s extended Zeilberger algorithm,the authors obtain two recurrence relations for Callan’s generalization of Narayana *** on these recurrence relations,the authors further prove the real-roote... 详细信息

关键词： Asymptotic normality Callan’s Narayana polynomials central limit theorem local limit theorem real zeros

Role of transient receptor potential vanilloid-1 in behavioral thermoregulation of the Mongolian gerbil Meriones unguiculatus

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Integrative Zoology 2022年第4期17卷 608-618页

作者： jing WEN Tingbei bo Zhijun zhao Dehua WANG State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijingChina School of Life and Environmental Sciences Wenzhou UniversityWenzhouChina CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijingChina School of Life Sciences Shandong UniversityQingdao 266237China

Ambient temperature considerably affects the physiology and behavior of *** and thermoregulatory abilities play an important role in the response to changing ambient temperature in ***,the molecular mechanisms of behavioral thermoregulation remain poorly *** receptor potential vanilloid-1(TRPV1)is activated by changes in ambient temperature and is involved in acute ***,we aimed to determine whether TRPV1 is involved in behavioral thermoregulation in wild rodents by conducting 2 *** the first,42 adult Mongolian gerbils(Meriones unguiculatus;14 per treatment)were randomly assigned to 3 housing temperatures(4,23,and 36℃for 4 *** the second,20 gerbils(10 per treatment)were randomly injected with capsaicin(TRPV1 agonist)or AMG517(TRPV1 antagonist).The results showed a significant decrease in food intake and non-shivering thermogenesis in the gerbils housed at 36℃.Additionally,there was a significant increase in the preference of gerbils housed at 4℃ to low *** expression of TRPV1 protein in the brown adipose tissue(BAT)and liver was significantly positively correlated with that of protein kinase A(PKA).The expression of TRPV1 and PKA proteins in the BAT was positively correlated with the temperature preference of the *** gerbils injected with capsaicin preferred significantly lower temperatures than the control group *** findings suggest that TRPV1 and PKA are involved in behavioral thermoregulation in Mongolian gerbils.

关键词： brown adipose tissue(BAT) capsaicin Mongolian gerbils protein kinase A(PKA) transient receptor potential vanilloid-1(TRPV1)

Adsorption and desorption properties for rhenium using a kind of weak-base anion resin

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Rare Metals 2018年第8期37卷 707-715页

作者： Hong-zhao Liu bo Zhang Xiao-jing jing Wei Wang Li-Jun Wang Rare Metal and Metallurgy Materials Research Institute General Research Institute for Nonferrous Metals Beijing 100088 China Zhengzhou Institute of Multipurpose Utilization oI Mineral Resources Zhengzhou 450006 China Key Laboratory of Evaluation and Multipurpose Utilization of Polymetallic Ore of Ministry of Land and Resources Zhengzhou 450006 China

In this paper, a weak-base resin was adopted to recycle rhenium because of its excellent adsorption and desorption properties for rhenium, while the kinetics and thermodynamics properties of adsorbing rhenium from the rhenium stock solution were systematically investigated. The kinetics investigations confirm that the adsorption process of Re belongs to kinetic control by particle diffusion process and the corresponding reaction rate constant is 2.68 × 10-s s^-1. Then, the Langmuir and Freundlich models were used to describe the adsorption equilibrium behaviors of Re and the thermodynamics parameters are obtained. The results show that the Langmuir model is the best-fitted model, and the Gibbs free energy change of Re adsorption onto ZS 15 weak-base resin is AGO = - 10.59 ＋ 12.66T. To verify the weak-base resins for extracting rhenium in industrial application, the column experiments were operated in the spray solution generating by roasting the molybdenum concentrates. The results indicate that the weak-base resins possess excellent adsorptive selectivity for rhenium, and the ammonia solution with low concentration could sufficiently desorb rhe- nium from the resins.

关键词： Rhenium Weak base Thermodynamics Kinetics

Bimetal nanoparticles hybridized with carbon nanotube boosting bifunctional oxygen electrocatalytic performance

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Rare Metals 2022年第8期41卷 2616-2623页

作者： Chen Sun Yong-Jie zhao Xuan-Yi Yuan jing-bo Li Hai-bo Jin Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing100081China Beijing Key Laboratory of Opto-Electronic Functional Materials&Micro-Nano Devices Department of PhysicsRenmin University of ChinaBeijing100872China

Developing bifunctional oxygen catalysts with high efficiency and low cost to replace platinum-group metal catalysts commonly utilized in metal-air batteries is critically *** this article,a convenient method to synthesis NiFe nanoparticles hybridized with N-doped carbon nanotube(NiFe@N-CNTs)is *** performance analysis indicates that Ni_(x)Fc_(1-x)@N-CNTs offers favorable oxygen reduction reaction(ORR)kinetics(onset potential(E_(onset))is 0.87 V and half-wave potential(E_(1/2))is0.84 V),together with excellent oxygen evolution reaction(OER)performance(an overpotential of 270 mV to drive10 mA·cm^(-2)).Contributed by the synergetic effect between NiFe alloy and N-CNTs,when being utilized as air cathode,rechargeable Zn-air batteries present superior cycling stability for over 150 *** research provides a universal strategy to synthesize the hybrids of intertwined carbon nanotube matrix loaded with alloy nanoparticles.

关键词： NiFe alloy Oxygen evolution reaction(OER) Oxygen reduction reaction(ORR) Zn-air batteries

Molecular mechanism and research progress of traditional Chinese medicine in the treatment of prostate cancer

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Traditional Medicine Research 2025年第1期10卷 62-72页

作者： Hai-Luo Wang Ruo-Ran Zhang Hao Wang Peng Xu jing-Kai Wang bo Chen Hao Xu Deng Pan Yu-Yang Ma Kun Pang Department of Urology Xuzhou Central HospitalXuzhou Clinical School of Xuzhou Medical CollegeXuzhou 221009China Graduate School Jiangsu UniversityZhenjiang 212013China Graduate School Bengbu Medical UniversityBengbu 233040China Department of Urology The Peixian People’s HospitalXuzhou 221699China.

Prostate cancer(PCa)is one of the most common malignant tumors in the male genitourinary system,ranking second in incidence *** Chinese medicine(TCM),as an important component of complementary and alternative medicine,shows unique advantages in cancer *** herbal medicine is usually composed of multiple ingredients and involves multiple signaling pathways,which showed function of inducing apoptosis of cancer cells,arresting the cell cycle,inhibiting invasion and metastasis,reducing drug resistance,and regulating immune *** therapy is also an important treatment of ***,Physical therapy such as acupuncture or Tai Chi and Qigong are gaining increased recognition in the management of PCa,particularly in addressing issues like urinary incontinence and bone metastasis-related *** article reviews the TCM treatment and therapy of PCa,in order to provide new research avenues and treatment options for the treatment of PCa with TCM and improve the quality of life of patients.

关键词： traditional Chinese medicine prostate cancer Chinese herbal medicine physical therapy

Analytical solution for earthquake induced hydrodynamic pressure on a circular cylinder in a two-layer fluid

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Journal of Hydrodynamics 2020年第5期32卷 901-913页

作者： Pi-guang Wang Mi zhao Xiu-li Du jing-bo Liu Key Laboratory of Urban Security and Disaster Engineering of Ministry of Education Beijing University of TechnologyBeijing 100124China College of Architecture and Civil Engineering Beijing University of TechnologyBeijing 1000124China Department of Civil Engineering Tsinghua UniversityBeijing 100084China

The analytical method is adopted to investigate the earthquake-induced hydrodynamic pressure on a circular cylinder surrounded by a two-layer *** on the radiation theory,the analytical expressions of the hydrodynamic pressure and the hydrodynamic force on a rigid circular cylinder are ***,the dispersion relation for the radiation problem in a two-layer fluid,and the added mass and the damping coefficients on the circular cylinder are *** earthquake-induced hydrodynamic forces on the circular cylinder in a two-layer fluid are furtherly *** is founded that the hydrodynamic pressures on the circular cylinder include not only the surface-wave and perturbing wave modes,but also the internal-wave *** is quite different from the case in a single-layer ***,the results indicate that the internal-wave mode has little influence on the hydrodynamic forces on the circular cylinder in a two-layer ***,the seismic responses of the flexible cylinder in single-layer and two-layer fluids are *** examples show that the seismic responses of the cylinder in a two-layer fluid are much larger than those in a single-layer fluid.

关键词： Circular cylinder earthquake hydrodynamic force surface wave two-layer fluid