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Occurrence and Reduction of Hepatitis B Vaccine Hesitancy Among Medical University Students—Shanxi Province,China,2020

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China CDC weekly 2024年第19期6卷 431-436,I0005-I0007页

作者： Huijuan Kong Xufeng Cui Ying Zhang Qiang Xue jing shi Tian Yao Yana Guo Xiuyang Xu Suping Wang Yongliang Feng School of Public Health Shanxi Medical UniversityTaiyuan CityShanxi ProvinceChina Center of Clinical Epidemiology and Evidence Based Medicine Shanxi Medical UniversityTaiyuan CityShanxi ProvinceChina Key Laboratory of Coal Environmental Pathogenicity and Prevention(Shanxi Medical University) Ministry of EducationTaiyuan CityShanxi ProvinceChina First Hospital/First Clinical Medical College of Shanxi Medical University Taiyuan CityShanxi ProvinceChina

Summary What is already known about this topic?Previous research has primarily examined the issue of hepatitis B vaccine hesitancy in migrant workers and other adult ***,there is a lack of studies that have specifical... 详细信息

关键词： Shanxi primarily workers

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科学社会主义理论逻辑研究的方法论思考

湘潭大学学报（哲学社会科学版） 2024年第4期48卷 125-131页

作者：荆世群湘潭大学马克思主义学院湖南湘潭411105

科学社会主义理论逻辑是科学社会主义理论分析和阐述其基本观点的内在逻辑,既包括其论证主题,也包括其论证方式,深刻揭示了人类社会从资本主义走向社会主义的发展规律和科学社会主义基本原则及其理论依据,集中体现了马克思主义立场、观... 详细信息

科学社会主义理论逻辑是科学社会主义理论分析和阐述其基本观点的内在逻辑,既包括其论证主题,也包括其论证方式,深刻揭示了人类社会从资本主义走向社会主义的发展规律和科学社会主义基本原则及其理论依据,集中体现了马克思主义立场、观点和方法的内在联系。我们可以把马克思恩格斯阐述的科学社会主义理论逻辑称为科学社会主义原生理论逻辑,而把列宁阐述的科学社会主义理论逻辑称为科学社会主义派生理论逻辑。这样就把科学社会主义理论逻辑层次化了。科学社会主义理论逻辑的层次化可以集中反映科学社会主义理论形态的历史发展,能够更清晰地呈现科学社会主义理论发展的思想脉络。深刻把握科学社会主义理论逻辑是我们正确理解和运用马克思主义理论、坚持和发展马克思主义中国化事业的必然要求。

关键词：科学社会主义理论逻辑中国特色社会主义方法论中国式现代化

鄂尔多斯盆地东缘晋西挠褶带中段构造特征及演化

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地质科学 2024年第3期59卷 723-731页

作者：石婧何登发中国地质大学(北京)能源学院北京100083

现今晋西挠褶带作为鄂尔多斯盆地的残余东部边界存在,近年来在上古生界石炭系—二叠系中发现有煤层气、致密气等丰富的油气资源,是一个重要的勘探领域。本文基于野外露头、钻井、地震资料等,明确其地层发育分布特征,结合浅表露头构建区... 详细信息

现今晋西挠褶带作为鄂尔多斯盆地的残余东部边界存在,近年来在上古生界石炭系—二叠系中发现有煤层气、致密气等丰富的油气资源,是一个重要的勘探领域。本文基于野外露头、钻井、地震资料等,明确其地层发育分布特征,结合浅表露头构建区域地质剖面,并利用2D-move软件对其进行反演分析与正演模拟,同时对其构造变形进行定量分析,研究表明:1)鄂尔多斯东缘晋西挠褶带中段主要在燕山期受东西向的挤压应力以及深部构造楔活动影响发生陆内构造变形,并遭受强烈的差异风化剥蚀作用,形成现今构造格局。2)研究区剖面现今长度约为114.96 km,以寒武系为标志层,燕山期地层缩短约4.06 km,地层抬升约6.12 km,地层缩短率为3.41%。3)晋西挠褶带中段形成原因为受到多方向的挤压构造应力作用,主要动力来源为古太平洋板块的西向低角度俯冲挤压。晋西挠褶带中段是重要构造单元,具深刻的动力来源。本文可为之后鄂尔多斯盆地东缘的陆内构造变形、演化特征研究以及油气勘探方向提供参考依据。

关键词：华北克拉通鄂尔多斯盆地晋西挠褶带构造特征构造演化

Lipid-lowering effects of gefarnate in statin-treated patients with residual hypertriglyceridemia:a randomized controlled study

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Journal of Geriatric Cardiology 2024年第8期21卷 791-798页

作者： jing shi Ming-Lu XU Mei-Jiao HE Wan-Lan BO Hai-Yu ZHANG Dang-Hui SUN Ding-Yu WANG Xiao-Yu WANG Qun SHAO Yu-Jiao PAN Yu ZHANG Chen-Guang DAI jing-Ying WANG Lin-Wei ZHANG Guang-Zhong LIU Yue LI for the GPROT Study Group Department of Cardiology the First Affiliated HospitalHarbin Medical UniversityHarbinChina Department of Gastroenterology the Fourth Affiliated HospitalHarbin Medical UniversityHarbinChina Department of Cardiology Harbin Medical University Cancer HospitalHarbinChina Department of Cardiology Shenzhen People’s HospitalShenzhenChina National Key Laboratory of Frigid Zone Cardiovascular Diseases Harbin Medical UniversityHarbinChina NHC Key Laboratory of Cell Transplantation Key Laboratory of Cardiovascular Disease Acousto-Optic Electromagnetic Diagnosis and Treatment in Heilongjiang ProvinceHeilongjiang Province Clinical Medical Research Center for Hypertensionthe First Affiliated HospitalHarbin Medical UniversityHarbinChina Institute of Metabolic Disease Heilongjiang Academy of Medical ScienceHarbinChina 不详

BACKGROUND The prevention of coronary artery disease(CAD)faces dual challenges:the aspirin-induced gastrointestinal injury,and the residual cardiovascular risk after statin *** acetate(Gefarnate)is an anti-ulcer *** was reported that geraniol might participate in lipid metabolism through a variety of *** aim of this study was to assess the lipid-lowering effects of gefarnate in statin-treated CAD patients with residual *** In this prospective,open-label,randomized,controlled trial,69 statin-treated CAD patients with residual hypertriglyceridemia were randomly assigned to gefarnate group and control group,received gefarnate(100 mg/3 times a day)combined with statin and statin alone,*** baseline and after one-month treatment,the levels of plasma triglyceride,high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)and total cholesterol were *** After one-month gefarnate treatment,triglyceride level was significantly lowered from 2.64 mmol/L to 2.12 mmol/L(P=0.0018),LDL-C level lowered from 2.7 mmol/L to 2.37 mmol/L(P=0.0004),HDL-C level increased from 0.97 mmol/L to 1.17mmol/L(P=0.0228).Based on statin therapy,gefarnate could significantly reduce the plasma triglyceride level(P=0.0148)and increase the plasma HDL-C level(P=0.0307).Although the LDL-C and total cholesterol levels tended to decrease,there was no statistically significant *** The addition of gefarnate to statin reduced triglyceride level and increased HDL-C level to a significant extent compared to statin alone in CAD patients with residual *** suggested that gefarnate might provide the dual benefits of preventing gastrointestinal injury and lipid lowering in CAD patients.

关键词： nat alone Lipid

Comparative study of nudged elastic band and molecular dynamics methods for diffusion kinetics in solid-state electrolytes

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Chinese Physics B 2024年第8期33卷 96-100页

作者：林啊鸣石晶魏苏淮孙宜阳 State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 201899China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Department of Physics Jiangxi Normal UniversityNanchang 330022China Eastern Institute of Technology Ningbo 315200China

Considerable efforts are being made to transition current lithium-ion and sodium-ion batteries towards the use of solid-state *** methods,specifically nudged elastic band(NEB)and molecular dynamics(MD)methods,provide powerful tools for the design of solid-state *** MD method is usually the choice for studying the materials involving complex multiple diffusion paths or having disordered ***,it relies on simulations at temperatures much higher than working *** paper studies the reliability of the MD method using the system of Na diffusion in MgO as a *** carefully study the convergence behavior of the MD method and demonstrate that total effective simulation time of 12 ns can converge the calculated diffusion barrier to about 0.01 *** calculated diffusion barrier is 0.31 eV from both *** diffusion coefficients at room temperature are 4.3×10^(-9) cm^(2)⋅s^(−1) and 2.2×10^(-9) cm^(2)⋅s^(−1),respectively,from the NEB and MD *** results justify the reliability of the MD method,even though high temperature simulations have to be employed to overcome the limitation on simulation time.

关键词： nudged elastic band method molecular dynamics solid electrolyte ion transport density func-tional theory

Diagnostic efficacy of virtual organ computer-assisted analysis in measuring the volume ratio of subchorionic hematoma with serum progesterone

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World Journal of Clinical Cases 2024年第17期12卷 3053-3060页

作者： Lin-Ling Shen jing shi Chang-Wei Ding Gao-Le Dai Qi Ma Department of Ultrasound The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina Department of Ultrasound Wuxi People’s Hospital of Nanjing Medical UniversityWuxi 211103Jiangsu ProvinceChina

BACKGROUND Subchorionic hematoma(SCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic *** can lead to adverse pregnancy outcomes such as miscarriage,preterm birth,and other *** detection and accurate assessment of SCH are crucial for appropriate management and improved pregnancy *** To evaluate the diagnostic efficacy of virtual organ computer-assisted analysis(VOCAL)in measuring the volume ratio of SCH to gestational sac(GS)combined with serum progesterone on early pregnancy outcomes in patients with *** A total of 153 patients with SCH in their first-trimester pregnancies between 6 and 11 wk were *** patients were followed up until a gestational age of 20 *** parameters of transvaginal two-dimensional ultrasound,including the circumference of SCH(Cs),surface area of SCH(Ss),circumference of GS(Cg),and surface area of GS(Sg),and the parameters of VOCAL with transvaginal three-dimensional ultrasound,including the three-dimensional volume of SCH(3DVs)and GS(3DVg),were *** size of the SCH and its ratio to the GS size(Cs/Cg,Ss/Sg,3DVs/3DVg)were recorded and *** Compared with those in the normal pregnancy group,the adverse pregnancy group had higher Cs/Cg,Ss/Sg,and 3DVs/3DVg ratios(P<0.05).When 3DVs/3DVg was 0.220,the highest predictive performance predicted adverse pregnancy outcomes,resulting in an AUC of 0.767,and the sensitivity,specificity were 70.2%,75%*** measuring 3DVs/3DVg combined with serum progesterone gave a diagnostic AUC of 0.824 for early pregnancy outcome in SCH patients,with a high sensitivity of 82.1%and a specificity of 72.1%,which showed a significant difference between *** VOCAL-measured 3DVs/3DVg effectively quantifies the severity of SCH,while combined serum progesterone better predicts adverse pregnancy outcomes.

关键词： Subchorionic hematoma Virtual organ computer-assisted analysis Gestational sac Serum progesterone Ultrasound parameters Adverse pregnancy outcomes

基于PLUS-InVEST模型的酒泉市生态系统碳储量时空演变与预测

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环境科学 2024年第1期45卷 300-313页

作者：石晶石培基王梓洋程番苑西北师范大学地理与环境科学学院兰州730070 甘肃省土地利用与综合整治工程研究中心兰州730070

基于“双碳”战略背景探讨西北干旱区土地利用变化对碳储量的影响及碳储量空间分异驱动因素,对提高区域生态系统碳汇增量和促进区域碳收支平衡具有重要意义.中国西北干旱区为自然生态极端脆弱区,随着新型城镇化快速推进,土地利用变化速... 详细信息

基于“双碳”战略背景探讨西北干旱区土地利用变化对碳储量的影响及碳储量空间分异驱动因素,对提高区域生态系统碳汇增量和促进区域碳收支平衡具有重要意义.中国西北干旱区为自然生态极端脆弱区,随着新型城镇化快速推进,土地利用变化速率明显加快并对生态系统碳储量及固持能力产生一定影响.运用PLUS-InVEST模型模拟了酒泉市2035年自然发展、集约发展、水资源约束和生态保护情景下碳储量的时空演变特征,并采用参数最优地理探测器模型分析了碳储量空间分异驱动力.结果表明:①1990~2020年酒泉市耕地、水域和建设用地面积呈显著增加趋势,其余土地利用类型面积呈减小趋势.②1990~2020年酒泉市碳储量从7722808.1 t增至7784371 t,草地转换成未利用地是造成区域碳储量损失的主要原因,占损失总量的85%.③2035年4种发展情景的碳储量均为增加趋势,其中生态保护情景增幅最为显著,增量为76989.29 t.④土地利用程度、人口密度、GDP密度和NDVI是酒泉市碳储量空间分异的主要驱动因子,其中土地利用程度解释力最强(q值为0.849),自然与人为因子的交互作用增强了各因子对碳储量空间分异的解释力.研究结果可为酒泉市生态系统综合管理及国土空间优化提供科学基础和决策依据.

关键词：碳储量 InVEST模型 PLUS模型参数最优地理探测器酒泉市

Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor

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Science China(Life Sciences) 2024年第7期67卷 1502-1513页

作者： Luo-Yuan Xia Xue-Feng Wang Xiao-Ming Cui Yi-Ming Zhang Zhen-Fei Wang En-Tao Li Chang-Fa Fan Ke Song Yuan-Guo Li Run-Ze Ye Fang-Xu Li Dai-Yun Zhu Jie Zhang Zhuang-Zhuang shi Ming-Zhu Zhang Liang-jing Li shi-jing Shen Song Jin Ya-Wei Zhang Wei-Guang Fu Lin Zhao Wen-Hao Wang Tie-Cheng Wang You-Chun Wang Jia-Fu Jiang Yan-Ling Hu Na Jia Yu-Wei Gao Wu-Chun Cao Institute of EcoHealth School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China Changchun Veterinary Research Institute Changchun 130122China State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyBeijing 100071China Division of Animal Model Research Institute for Laboratory Animal ResourcesNational Institutes for Food and Drug ControlBeijing 102629China National Institutes for Food and Drug Control Beijing 102629China Life Sciences Institute Guangxi Medical UniversityNanning 530020China College of Life Sciences Shandong Normal UniversityJinan 250014China Research Unit of Discovery and Tracing of Natural Focus Diseases Chinese Academy of Medical SciencesBeijing 100071China

Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins,showing a potential threat to *** we report the infectivity and pathogenicity of the SARS-CoV-2-related virus,PCoV-GX/P2V,which was isolated from a Malayan pangolin(Manis javanica).PCoV-GX/P2V could grow in human hepatoma,colorectal adenocarcinoma cells,and human primary nasal epithelial *** replicated more efficiently in cells expressing human angiotensin-converting enzyme 2(hACE2)as SARS-CoV-2 *** intranasal inoculation to the hACE2-transgenic mice,PCoV-GX/P2V not only replicated in nasal turbinate and lungs,but also caused interstitial pneumonia,characterized by infiltration of mixed inflammatory cells and multifocal alveolar *** population immunity established by SARS-CoV-2 infection and vaccination may not protect people from PCoV-GX/P2V *** findings further verify the hACE2 utility of PCoV-GX/P2V by in vivo experiments using authentic viruses and highlight the importance for intensive surveillance to prevent possible cross-species transmission.

关键词： pangolin SARS-CoV-2-related virus infectivity pathogenicity human cell lines human ACE2 receptor hACE2-transgenic mice

Efficacy of Pudilan Xiaoyan Oral Liquid in the treatment of pneumonia induced by drug-resistant Pseudomonas aeruginosa

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Infectious Diseases Research 2024年第3期5卷 22-29页

作者： jing Ma Yan-Yan Bao Xiao-Rui Wang Kuok Kuantai Leong-Man Chon Xiao-Lan Cui Ju-Ying Zhong Yu-jing shi Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China Conde S.Januário Hospital(CHCSJ) pharmacy departmentMacao 999078China Lin Fong Charities Traditional Chinese Medicine Treatment Centre Macao 999078China Experimental Research Center China Academy of Chinese Medical SciencesBeijing 100700China

Background:Pudilan Xiaoyan Oral Liquid(PDL)is a Chinese patent medicine with notable pharmacological properties,including anti-inflammatory and antibacterial ***-resistant Pseudomonas aeruginosa infection is a common and refractory bacterial infection in clinical *** to its high drug resistance,it brings great challenges to *** study aimed to assess the therapeutic efficacy of PDL in a murine model of pneumonia induced by drug-resistant Pseudomonas ***:Three different doses of PDL(11 mL/kg/d,5.5 mL/kg/d,2.75 mL/kg/d)were used to observe lung tissue pathology and inflammatory cytokine levels in pneumonia mouse models induced by multidrug-resistant Pseudomonas aeruginosa(MDR-PA).Additionally,the protective efficacy of PDL against mortality in infected mice was evaluated using a death model caused by *** sub-MIC concentration of levofloxacin was used to induce drug-resistant mice pneumonia model to evaluate the role of PDL in reversing drug *** data are expressed as mean±standard *** significance was determined by one-way analysis of variance followed by Tukey’s multiple-comparisons ***:Treatment effect of PDL on MDR-PA pneumonia:the medium and small doses of PDL can significantly reduce the lung index of multi-drug resistant bacteria infected pneumonia model mice(P<0.05),the lung index inhibition rates for these groups were 55.09%and 58.43%,and improve the degree of lung tissue lesions of mice;The expression of serum cytokines keratinocyte chemoattractant,tumor necrosis factor-αand monocyte chemoattractant protein-1 could be decreased in the three dosage groups of PDL(P<0.01).PDL treatment not only lowered the mortality but also extended the survival duration in mice infected with *** was found after sub-MIC concentration of levofloxacin induced resistance of Pseudomonas aeruginosa to pneumonia in *** with the model group,the lung index of mice in high

关键词： pudilan Pseudomonas aeruginosa drug resistance mice model