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Coupling of the recovery of earliest Silurian sponges and ocean redox conditions:Evidence from South China

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Journal of Palaeogeography 2023年第2期12卷 311-330页

作者： Yong Wang Joseph P.Botting jing-Qiang tan Ming Li Wen-Hui Wang School of Geosciences and Info-Physics Central South UniversityChangsha 410083Hunan ProvinceChina Department of Natural Sciences Amgueddfa Cymru-National Museum WalesCathays ParkCardiff CF103LPUK Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China

Many aspects of the Late Ordovician Mass Extinction(LOME)aftermath and recovery have been puzzling due to heterogeneities in tempo and triggering *** fossil groups,which are the most severely affected by oxidative stress,offer the best opportunities for understanding both biological and ecological recovery after the *** recent studies,deep-water sponge assemblages(which may have had high physiological tolerance to oxygen deviations)have been reported widely across South China in the immediate aftermath of the extinction *** order to further explore the lateral and temporal distributions of sponges,and ecological effects of benthic recovery during this critical interval,this study presents new Llandovery sponge assemblages recovered from two sections in Hunan Province,South China,accompanied by geochemical *** sponge communities are preserved by pyritic spicule replacements and shows a relatively deep-water affinity(estimated around 60-150 m in depth)comparable to several previously reported assemblages in South China,and consistent with the observed graptolite *** analysis of total organic carbon(TOC)and major and trace element composition in both sections show similar trends,indicating a shift in redox state of the bottom-water from persistent anoxia or intermittent euxinia in the earliest Rhuddanian,becoming oxygenated in the early *** on the present study and previous biological and geochemical data from South China,the distribution of early Silurian sponge assemblages in South China demonstrates a gradual expansion towards deeper regions when ocean redox conditions *** study confirms the continuity of the end-Ordovician sponge faunas and taxa,both laterally across South China,and temporally through the early *** pioneering colonization of sponges in low-oxygen environments after the LOME may have set the stage for the subsequent recovery of other benthic organisms.

关键词： Llandovery South China Graptolite Proliferation Geochemistry Ecological recovery

The relation between serum phosphorus levels and long-term mortality in Chinese patients with ST-segment elevation myocardial infarction

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Journal of Geriatric Cardiology 2019年第10期16卷 775-781页

作者： Guo-Hua ZHU Xi-Peng SUN Zhi LIU Zhen-Xing FAN Yan-Ling WANG jing tan jing LI Qi HUA Department of Cardiology Xuanwu Hospital Capital Medical University

Background Elevated serum phosphorus levels may be associated with adverse outcomes in cardiovascular disease. This study aimed to investigate the relation between serum phosphorus levels and risk of all-cause mortality in Chinese patients with ST-segment elevation myocardial infarction (STEMI) who had preserved renal function at baseline. Methods We enrolled patients with STEMI who had preserved renal function at baseline in Xuanwu Hospital from January 2011 to December 2016. Those patients were divided into four groups based on serum phosphorus levels. All-cause mortality rates were compared between groups. Mean duration of follow up was 54.6 months. We used Cox proportional-hazards models to examine the relation between serum phosphorus levels and all-cause mortality after adjustment for potential confounders. Results 1989 patients were involved and 211 patients (10.6%) died during follow-up. Based on serum phosphorus levels, patients were categorized into the following groups: 4.50 mg/dL (n = 162), respectively. The lowest mortality occurred in patients with serum phosphorus levels between 2.51–3.50 mg/dL, with a multivariable-adjusted hazard ratio of 1.19 (95% CI: 0.64–1.54), 1.37 (95% CI: 1.22–1.74), and 1.46 (95% CI: 1.35–1.83) in patients with serum phosphorus levels of 4.50 mg/dL, respectively. Conclusions Elevated serum phosphorus levels were associated with all-cause mortality in Chinese patients with STEMI who had preserved renal function at baseline.

关键词： Mortality Serum phosphorus levels ST-segment elevation myocardial infarction

Radial Anisotropy in the Crust beneath the Northeastern Tibetan Plateau from Ambient Noise Tomography

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Journal of Earth Science 2015年第6期26卷 864-871页

作者： jing tan Hongyi Li Xinfu Li Ming Zhou Longbin Ouyang Sanjian Sun Dan Zheng Key Laboratory of Geo-Detection Ministry of Education China University of Geosciences Geological Exploration Technologies Institute of Anhui Province School of Geophysics and Information Technology China University of Geosciences

Through analysis of Rayleigh wave and Love wave Green＇s functions estimated from ambient noise tomography, we obtain radial anisotropy and shear wave velocity structure beneath the northeastern Tibetan Plateau. With two hundred and twenty three broadband seismic stations deployed by China Earthquake Administration, a collaborative seismic experiment of northern Tibet（ACSENT） experiment and northeastern Tibet seismic（NETS） experiment provide the unprecedented opportunity to resolve the spatial distribution of the radial anisotropy within the crust of the northeastern Tibetan Plateau. Discrepancies between Love（sh） and Rayleigh（sv） wave velocities show complex anisotropic patterns associated with the dynamic processes of the collision between the Indian and Eurasian plates：（1） In the upper crust, V（sv）〉V（sh） anisotropy is dominant throughout the study area which probably reflects fossil microcracks induced by the uplift, folding and erosion geodynamic processes;（2） in the middle crust, V（sh）〉V（sv） observed beneath the Songpan-Ganzi terrane and the northwestern Qilian orogen correlates well with a mid-crustal low velocity zone（LVZ）;（3） at depths deeper than 40 km, V（sh）〉V（sv） is still found in the Songpan-Ganzi terrane. This anisotropy could be caused by the sub-horizontal alignment of anisotropic minerals that has followed the collision between India and Eurasia. However, the northwestern Qilian orogen is associated with V（sv）〉V（sh） anisotropy which may be related to the vertically aligned seismic anisotropic minerals caused by the crustal thickening.

关键词： northeastern Tibetan Plateau ambient noise tomography radial anisotropy.

A new guaianolide from the roots of Pterocypsela elata

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Chinese Chemical Letters 2013年第1期24卷 55-56页

作者： Yi-Xiao Bai jing tan Fu-Lin Yan Ming-Ming Ding Xiang Wang Pharmacy College Xinxiang Medical University Third Clinical College of Xinxiang Medical University

In order to find more biologically active substances, we have carefully investigated the chemical constituents of Pterocypsela elata. One new guaianolide, （4S）-ll-methoxycarbonyl-guaiane- l（10）,5（6）,7（11）,8（9）-tetraen-6,12-olide was isolated from the EtOAc extracts of the roots of P. elata. Its structure was elucidated by various spectroscopic methods and confirmed by X-ray crystallographic analysis.

关键词： CompositaePterocypsela elataSesquiterpene lactonesGuaianolide

Extracorporeal continuous portal diversion plus temporal plasmapheresis for “small-for-size” syndrome

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World Journal of Gastroenterology 2013年第33期19卷 5464-5472页

作者： Peng Hou Chao Chen Yu-Liang Tu Zi-Man Zhu jing-Wang tan Institute of Gastroenterology The First Affiliated Hospital of Chinese PLA General Hospital Institute of Hepatobiliary Surgery The First Affiliated Hospital of Chinese PLA General Hospital

AIM:To investigate the effect of plasmapheresis via the portal vein for"small-for-size"syndrome(SFSS)aided by extracorporeal continuous portal diversion(ECPD).METHODS:Extensive or total hepatectomy in the pig is usually adopted as a postoperative liver failure(PLF)or SFSS *** this study,animals which underwent85%-90%hepatectomy were randomized into either the Systemic group(n=7)or the Portal group(n=7).In the Systemic group,all pigs received temporal plasmapheresis(PP)via the extracorporeal catheter circuit(systemic to systemic circulation)from 24 to 30 h posthepatectomy(PH);in the Portal group,all pigs received ECPD to divert partial portal vein flow(PVF)to the systemic circulation after hepatectomy,then converted to temporal PP from 24 to 30 h PH,and subsequently converted to ECPD again until 48 h *** the Portal group,the PVF was preserved at 3.0-3.3 times that of the baseline value,similar to that following 70%hepatectomy,which was regarded as the optimal PVF to the hypertrophic liver *** 48 h PH,all pigs were re-opened and the portal vein pressure(PVP),PVF,and HAF(hepatic artery flow)were measured,and then diversion of the portal venous flow was ***1 h the PVP,PVF,and HAF were *** portal hemodynamic changes,liver injury,liver regeneration and bacterial/lipopolysaccharide(LPS)translocation were evaluated in the two ***:The PVP in the Portal group was significantly lower than that in the Systemic group during the time period from 2 to 49 h PH(P<0.05).Serum alanine aminotransferase(ALT),total bilirubin(TB)and ammonia were significantly reduced in the Portal group compared with the Systemic group from 24 to 48 h PH(P<0.05).The Portal group may have attenuated sinusoidal endothelial injury and decreased the level of HA compared with the Systemic *** the Systemic group,there was significant sinusoidal dilation,hydropic changes in hepatocytes and hemorrhage into the hepatic parenchyma,and the sinusoidal endothelial

关键词： Small-for-size syndrome Postoperative liver failure Extracorporeal portal diversion Plasmapheresis Hepatectomy

Should temporary extracorporeal continuous portal diversion replace meso/porta-caval shunts in “small-for-size” syndrome in porcine hepatectomy?

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World Journal of Gastroenterology 2015年第3期21卷 888-896页

作者： Da-Dong Wang Yong Xu Zi-Man Zhu Xiang-Long tan Yu-Liang Tu Ming-Ming Han jing-Wang tan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chinese PLA General Hospital

AIM:To investigate the feasibility of temporary extracorporeal continuous porta-caval diversion(ECPD) to relieve portal hyperperfusion in "small-for-size" syndrome following massive hepatectomy in ***:Fourteen pigs underwent 85%-90% liver resection and were then randomly divided into thecontrol group(n = 7) and diversion group(n = 7).In the diversion group,portal venous blood was aspirated through the portal catheter and into a tube connected to a centrifugal *** filtration,the blood was returned to the pig through a double-lumen catheter inserted into the internal jugular or subclavian *** the conversion pump,portal venous inflow was partially diverted to the inferior vena cava through a catheter inserted via the gastroduodenal vein at 100-130 m L/*** hemodynamics,injury,and regeneration in the liver remnant were compared between the two ***:Compared to the control group,porta-caval diversion via ECPD significantly mitigated excessive portal venous flow and portal vein pressure(PVP); the portal vein flow(PVF),hepatic artery flow(HAF),and PVP in the two groups were not significantly different at baseline; however,the PVF(431.8 ± 36.6 vs 238.8 ± 29.3,P < 0.01; 210.3 ± 23.4 vs 122.3 ± 20.6,P < 0.01) and PVP(13.8 ± 2.6 vs 8.7 ± 1.4,P < 0.01; 15.6 ± 2.1 vs 10.1 ± 1.3,P < 0.05) in the control group were significantly higher than those in the diversion group,*** HAF in the control group was significantly lower than that in the diversion group at 2 h and 48 h post hepatectomy,and ECPD significantly attenuated injury to the sinusoidal lining and hepatocytes,increased the regeneration index of the liver remnant,and relieved damage that the liver remnant suffered due to endotoxin and bacterial ***:ECPD,which can dynamically modulate portal inflow,can reduce injury to the liver remnant and facilitate liver regeneration,and therefore should replace permanent meso/porta-caval shunts in "smallfor-size" synd

关键词： small-for-size syndrome Extracorporeal continuous

Photocatalytic Decarboxylative Minisci Reaction Catalyzed by Palladium-Loaded Gallium Nitride

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Precision Chemistry 2023年第7期1卷 437-442页

作者： Lida tan Hyotaik Kang Mingxin Liu Hui Su jing-tan Han Chao-Jun Li Department of Chemistry and FQRNT Centre for Green Chemistry and CatalysisMcGill UniversityMontrealQC H3A 0B8Canada State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhouGansu 730000China

The decarboxylative Minisci reaction is a versatile tool for the direct C-H alkylation of heteroarenes,where stoichiometric amounts of oxidants or expensive,precious metal reagents are commonly ***,we reported a photodriven decarboxylative Minisci reaction enabled by a gallium nitride-based heterogeneous photocatalyst under mild *** method can be effectively applied to a broad substrate scope of acids,including primary,secondary,and tertiary carboxylic acids and N-heteroarenes *** practicability and robustness of the approach are demonstrated for the functionalization of biologically active compounds.

关键词： Heterogeneous catalysis Minisci reaction Photocatalytic decarboxylation N-heteroarenes C-H alkylation Gallium nitride

Anacardic acid(6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling

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Chinese Journal of Cancer Research 2012年第4期24卷 275-283页

作者： jing tan Binghai Chen Leye He Yuxin tang Zhiqiang Jiang Guangmin Yin Jinrong Wang Xianzhen Jiang Department of Urology the third Xiangya Hospital of Xiangya Medical CollegeCentral South University

Anacardic acid （AA） is a mixture of 2-hydroxy-6-alkylbenzoic acid homologs. It is widely regarded as a non-specific histone acetyltransferase inhibitor of p300. The effects and the mechanisms of AA in LNCaP cells （prostate cancer cells） remain unknown. To investigate the effect of AA on LNCaP cells, we had carried out several experiments and found that AA inhibits LNCaP cell proliferation, induces G1/S cell cycle arrest and apoptosis of LNCaP cell. The mechanisms via which AA acts on LNCaP cells may be due to the following aspects. First, AA can regulate p300 transcription and protein level except for its mechanisms regulating function of p300 through post-translational modification in LNCaP cells. Second, AA can activate p53 through increasing the phosphorylation of p53 on Serl 5 in LNCaP cells. AA can selectively activate p21 （target genes of p53）. Third, AA can down-regulates androgen receptor （All） through supressing p300. Our study suggests that AA has multiple anti-tumor activities in LNCaP cells and warrants further investigation.

关键词： Prostate cancer anacardic acid apoptosis LNCaP p300 p53

Osteoblast behaviors on titania nanotube and mesopore layers

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Regenerative Biomaterials 2017年第2期4卷 81-87页

作者： Yan Zhang Rong Luo jing tan Jianxin Wang Xiong Lu Shuxin Qu Jie Weng Bo Feng Key Laboratory of Advanced Technologies of Materials Ministry of EducationSchool of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031PR China

Titania nanotubes and mesopores with different diameter sizes were prepared by electrochemical oxidation of *** responses of osteoblastic cells isolated from Sprague–Dawley rats to the nanotube and mesopore layers were investigated in sequential events of cell adhesion,morphology,actin cytoskeleton,proliferation,differentiation,and ***-structural features,especially diameters of the nanotubes and mesopores,obviously influenced on cell behaviors in the sequential *** cells showed better proliferation and differentiation abilities on the specimens with the nanotubes and mesopores than on flat titanium *** levers of calcium mineralization were observed on the nanotube and mesopore *** cells adhered much faster onto the nanotubes with about 170nm diameter and the mesopores with about 400nm diameter than onto flat titanium disk and 50nm *** is an appropriate range of the tube/pore sizes,and in this present work,titania nantubes with 170nm diameter is the best for enhancing functions of osteoblasts.

关键词： nanotube mesopore osteoblast adhesion proliferation mineralization