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Glaucoma drainage device implantation and cyclophotocoagulation in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 257-264页

作者： min-Shu Wang Xue-Chuan Dong mi-Yun Zheng Xiang Fan Ge-Ge Xiao jing Hong Ling-Ling Wu Department of Ophthalmology Peking University Third HospitalBeijing 100191China Key Laboratory of Restoration of Damaged Ocular Nerve Beijing 100191China NIMO Ophthalmology Research Institute Beijing 100176China Department of Ophthalmology the First Hospital of PutianTeaching HospitalFujian Medical UniversityPutian 351100Fujian ProvinceChina

AIM:To compare the surgical outcomes of glaucoma drainage device implantation(GDI)and trans-scleral neodymium:YAG cyclophotocoagulation(CPC)in the management of refractory glaucoma after Descemetstripping automated endothelial keratoplasty(DSAEK).METHODS:This retrospective study on observational case series enrolled 29 patients who underwent DSAEK and posterior anti-glaucoma surgery(15 with GDI and 14 with CPC).The main outcome measures were intraocular pressure(IOP),glaucoma surgery success rate(defined as IOP of 6–21 mm Hg without additional anti-glaucoma operation),number of glaucoma medications,endothelial graft status,and best-corrected visual acuity(BCVA).RESULTS:The mean follow-up time was 34.1 and 21.0mo for DSAEK or glaucoma surgeries,both for the GDI and CPC *** groups showed significant IOP reduction after glaucoma *** GDI group presented a significantly higher success rate in IOP control than the CPC group(60%vs 21.4%,P=0.03).Both procedures significantly decreased the number of glaucoma medications(P=0.03).Forty percent and 57%of cases in the GDI and the CPC group,respectively,experienced endothelial graft failure during follow-up(P=0.36).Significantly worse BCVA after surgery was observed in the CPC group but not in the GDI ***:Both GDI and CPC significantly decrease IOP in eyes with glaucoma after *** is preferable to CPC in refractory glaucoma cases after DSAEK,as it manifests a significantly higher success rate for IOP control,similar endothelial graft failure rate,and relatively preserves BCVA than CPC.

关键词： glaucoma drainage device implantation cyclophotocoagulation refractory glaucoma Descemetstripping automated endothelial keratoplasty

Transcatheter arterial chemoembolization combined with PD-1 inhibitors and Lenvatinib for hepatocellular carcinoma with portal vein tumor thrombus

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World Journal of Gastroenterology 2024年第8期30卷 843-854页

作者： Hong-Xiao Wu Xiao-Yan Ding Ya-Wen Xu ming-Hua Yu Xiao-mi Li Na Deng jing-Long Chen Cancer Center Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

BACKGROUND Hepatocellular carcinoma(HCC)patients complicated with portal vein tumor thrombus(PVTT)exhibit poor prognoses and treatment *** To investigate efficacies and safety of the combination of PD-1 inhibitor,transcatheter arterial chemoembolization(TACE)and Lenvatinib in HCC subjects comorbid with *** From January 2019 to December 2020,HCC patients with PVTT types Ⅰ-Ⅳ were retrospectively enrolled at Beijing Ditan *** were distributed to either the PTL or TACE/Lenvatinib(TL)*** median progression-free survival(mPFS)was set as the primary endpoint,while parameters like median overall survival,objective response rate,disease control rate(DCR),and toxicity level served as secondary *** Forty-one eligible patients were finally recruited for this study and divided into the PTL(n=18)and TL(n=23)*** a median follow-up of 21.8 months,the DCRs were 88.9%and 60.9%in the PTL and TL groups(P=0.046),***,mPFS indicated significant improvement(HR=0.25;P<0.001)in PTL-treated patients(5.4 months)compared to TL-treated(2.7 months)*** were no treatment-related deaths or differences in adverse events in either *** A triplet regimen of PTL was safe and well-tolerated as well as exhibited favorable efficacy over the TL regimen for advanced-stage HCC patients with PVTT types Ⅰ-Ⅳ.

关键词： Hepatocellular carcinoma Transcatheter arterial chemoembolization Lenvatinib PD-1 inhibitor Portal vein tumor thrombus

Computer-assisted three-dimensional individualized extreme liver resection for hepatoblastoma in proximity to the major liver vasculature

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1066-1077页

作者： Wen-Li Xiu Jie Liu jing-Li Zhang jing-miao Wang Xue-Feng Wang Fei-Fei Wang Jie mi Xi-Wei Hao NanXia Qian Dong Department of Pediatric Surgery The Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Pediatric Surgery Yijishan Hospital of Wannan Medical CollegeWuhu 241000Anhui ProvinceChina Shandong Provincial Key Laboratory of Digital Medicine and Computer-assisted Surgery Shandong College Collaborative Innovation Center of Digital Medicine Clinical Treatment and Nutrition HealthQingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND The management of hepatoblastoma(HB)becomes challenging when the tumor remains in close proximity to the major liver vasculature(PMV)even after a full course of neoadjuvant chemotherapy(NAC).In such cases,extreme liver resection can be considered a potential *** To explore whether computer-assisted three-dimensional individualized extreme liver resection is safe and feasible for children with HB who still have PMV after a full course of *** We retrospectively collected data from children with HB who underwent surgical resection at our center from June 2013 to June *** then analyzed the detailed clinical and three-dimensional characteristics of children with HB who still had PMV after a full course of *** Sixty-seven children diagnosed with HB underwent surgical *** age at diagnosis was 21.4±18.8 months,and 40 boys and 27 girls were ***-nine(88.1%)patients had a single tumor,39(58.2%)of which was located in the right lobe of the liver.A total of 47 patients(70.1%)had PRE-TEXT III or ***-nine patients(58.2%)underwent delayed *** a full course of NAC,16 patients still had close PMV(within 1 cm in two patients,touching in 11 patients,compressing in four patients,and showing tumor thrombus in three patients).There were 6 patients of tumors in the middle lobe of the liver,and four of those patients exhibited liver anatomy *** 16 children underwent extreme liver resection after comprehensive preoperative *** procedures were performed according to the preoperative plan,and the operations were successfully ***,the 3-year event-free survival of 67 children with HB is 88%.Among the 16 children who underwent extreme liver resection,three experienced recurrence,and one died due to multiple *** Extreme liver resection for HB that is still in close PMV after a full course of NAC is both safe and *** approach not only reduces th

关键词： Children Hepatoblastoma Surgery Three-dimensional Computer-assisted

A review of high-temperature selective absorbing coatings for solar thermal applications

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Journal of Materiomics 2020年第1期6卷 167-182页

作者： Ke Xu miao Du Lei Hao jing mi Qinghe Yu Shijie Li GRINM Group Co. Ltd.National Engineering Research Center of Nonferrous Metals Materials and Products for New Energy100088China GRIMAT Engineering Institute Co. Ltd.101407China

Solar selective absorbing coatings directly harvest solar energy in the form of *** higher temperatures are required to drive higher power-cycle efficiencies in favor of lower costs of *** to different dielectrics,high temperature coatings can mainly be divided to double cermet solar selective coatings,transition metal nitride multilayer coatings and transition metal oxide multilayer *** paper assesses the photothermal conversion efficiency and thermal stability,and discusses the challenges and strategies of improving both thermal and optical *** cermet layers can stabilize nanocrystalline structures by alloying,while transition metal nitride/oxide layers generally choose the reliable materials with superior mechanical properties and thermal *** purpose of this review is to get the optimized systems,and propose further research directions at higher temperature,such as all-ceramic absorbing coatings.

关键词： High temperature Solar selective absorbing coatings Photothermal conversion efficiency Spectral selectivity Thermal stability

Properties and microstructure of copper–titanium alloys with magnesium additions

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Rare Metals 2024年第5期43卷 2290-2299页

作者： Lue Huang Li-Jun Peng Jiang Li Xu-Jun mi Gang Zhao Guo-Jie Huang Hao-Feng Xie Yi-Cheng Cao Wen-jing Zhang Zhen Yang State Key Laboratory of Nonferrous Metals and Processes GRINM Group Co.Ltd.Beijing 100088China GRIMAT Engineering Institute Co. LtdBejing 101407China School of Materials Science and Engineering Northeastern UniversityShenyang110000China General Research Institute for Nonferrous Metals Beijing 100088China China Academy of Space Technology Beijing 100094China China Nonferrous Metals mining Group(Tianjin)Co.Ltd Tianjin 3001llChina

The volume fractions and morphology of precipitates in precipitation-strengthened Cu-Ti alloys,which precipitate mainly as continuous and discontinuous precipitates,are important for the application of the *** study employed hardness and electrical conductivity tests transmission electron microscopy(TEM),atom probe tomography(APT),and first-principles calculations to demonstrate that the addition of Mg is effective for accelerating nanosized continuousβ'-Cu_(4)Ti precipitation as well as for suppressing the precipitation of coarse lamellar discontinuousβ-Cu_(4)Ti precipitates along the grain boundaries,resulting in Cu-Ti alloys with high yield strength and good electrical *** results showed that the continuous precipitation ofβ'-Cu_(4)Ti was accelerated by the Mg additions,which reduced the supersaturation of the matrix,thereby reducing the chemical driving force for the discontinuous *** the other hand,Mg additions increased the mismatch between the discontinuousβ-Cu_(4)Ti precipitates and matrix decreased the nucleation rate of the discontinuous precipitates,and increased the spacing of the discontinuous precipitation layer,resulting in a lower growth rate of the discontinuous ***,the addition of Mg to Cu-Ti alloys enhances the strength and improves the resistance to over-ageing.

关键词： Cu-Ti-Mg alloy Precipitation hardening Discontinuous precipitation Continuous precipitation microstructure formation mechanism

Laves phase hydrogen storage alloys for super-high-pressure metal hydride hydrogen compressors

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Rare Metals 2011年第3期30卷 227-231页

作者： GUO Xiumei WANG Shumao LIU Xiaopeng LI Zhinian LU Fang mi jing HAO Lei JIANG Lijun Energy Material and Technology Institute General Research Institute for Nonferrous Metals Beijing 100088 China

Ti-Cr- and Ti-Mn-based alloys were prepared to be low- and high-pressure stage metals for a double-stage super-high-pressure metal hydride hydrogen compressor. Their crystallographic characteristics and hydrogen storage properties were investigated. The alloy pair Ti0.9Zr0.1Mn1.4-Cr0.35V0.2Fe0.05/TiCr1.55Mn0.2Fe0.2 was optimized based on the comprehensive performance of the studied alloys. The product hydrogen with a pressure of 100 MPa could be produced from 4 MPa feed gas when hot oil was used as a heat reservoir.

关键词： hydrogen storage alloys hydrides Laves phase compressors hydrogen

新知识经济时代饲料企业人力资源高效管理路径分析

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中国饲料 2022年第20期 103-106页

作者：米静庞博石家庄理工职业学院河北石家庄050228 河北政法职业学院河北石家庄050046

新知识经济时代,我国饲料企业在管理方面取得重大突破,特别是人力资源管理领域。为将新知识经济的成果更广泛地融入饲料企业人力资源管理中,饲料企业应根据自身人力资源管理实际情况,结合新知识经济的优势,针对当前存在的人力资源管理... 详细信息

新知识经济时代,我国饲料企业在管理方面取得重大突破,特别是人力资源管理领域。为将新知识经济的成果更广泛地融入饲料企业人力资源管理中,饲料企业应根据自身人力资源管理实际情况,结合新知识经济的优势,针对当前存在的人力资源管理意识欠缺、管理资金不足、管理模式落后等问题探寻对策,促进企业自身人力资源管理水平的提升,推动人力资源管理走向知识化、科学化管理的新阶段。

关键词：新知识经济饲料企业人力资源管理模式

中国职业教育国际话语权的历史嬗变与时代趋向

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现代教育管理 2023年第1期 99-107页

作者：米靖王珩安天津职业技术师范大学职业教育学院天津300222

中国职业教育国际话语权在国际交流合作中具有重要意义,提升职业教育国际话语权亦是新时代引领世界职业教育改革发展、构建人类命运共同体的关键。改革开放以来,中国职业教育国际话语权从无到有、由弱变强,经历了奠基、初塑、转型、成... 详细信息

中国职业教育国际话语权在国际交流合作中具有重要意义,提升职业教育国际话语权亦是新时代引领世界职业教育改革发展、构建人类命运共同体的关键。改革开放以来,中国职业教育国际话语权从无到有、由弱变强,经历了奠基、初塑、转型、成型四个阶段。从历史实践中汲取经验,转化世界职业技术教育发展大会成功举办所取得的成果,从健全完善职业教育国际交流合作的保障机制、构建推广中国特色职业教育的话语体系、优化拓展中国主导的职业教育交流合作平台、打造宣介中国职业教育故事的优质品牌四个维度来提升职业教育国际话语权。

关键词：职业教育国际化国际话语权历史嬗变时代趋向中国特色职业教育

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Developing aptamers into tumor diagnostics and therapeutics

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中国肿瘤生物治疗杂志 2008年第4期15卷 301-304页

作者： jing mi Bruce A. Sullenger Bryan M. Clary Departments of Surgery Duke University Medical Center DurhamNC 27710 USA

Aptamers are small single-stranded nucleic acid molecules that bind a target protein with high affinity and *** to their stability,low toxicity and immunogenicity,as well as improved safety,aptamers are attractive alternatives to antibody and are therefore suitable for in vivo *** are typically isolated,through a process termed SELEX(systematic evolution of ligands by exponential enrichment),from combinatorial libraries with desired *** the present review,the recent non-conventional aptamer selection process will be discussed together with an overview on the aptamer application in cancer diagnosis and therapy.

关键词：肿瘤诊断方法治疗方法蛋白质