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Quenching and flow of charm and bottom quarks via semi-leptonic decay of D and B mesons in Pb+Pb collisions at the LHC

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Chinese Physics C 2024年第8期48卷 190-197页

作者： Shu-Qing Li Wen-jing xing Shanshan Cao Guang-You Qin School of Physics and Electronic Engineering Jining UniversityQufu 273155China Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Institute of Particle Physics and Key Laboratory of Quark and Lepton Physics(MOE) Central China Normal UniversityWuhan 430079China

Heavy flavor particles provide important probes of the microscopic structure and thermodynamic properties of the quark-gluon plasma(QGP)produced in high-energy nucleus-nucleus *** studied the energy loss and flow of charm and bottom quarks inside the QGP via the nuclear modification factor(R_(AA))and elliptic flow coefficient(v_(2))of their decayed leptons in heavy-ion collisions at the *** dynamical evolution of the QGP was performed using the CLVisc(3+1)-dimensional viscous hydrodynamics model;the evolution of heavy quarks inside the QGP was simulated with our improved Langevin model that considers both collisional and radiative energy loss of heavy quarks;the hadronization of heavy quarks was simulated via our hybrid coalescence-fragmentation model;and the semi-leptonic decay of D and B mesons was simulated via *** the same spatial diffusion coefficient for charm and bottom quarks,we obtained smaller R_(AA) and larger v_(2) of charm decayed leptons than bottom decayed leptons,indicating stronger energy loss of charm quarks than bottom quarks inside the QGP within our current model setup.

关键词： quark-gluon plasma heavy-ion collisions jet quenching anisotropic flow heavy quark heavy flavor muon

TransCell:In Silico Characterization of Genomic Landscape and Cellular Responses by Deep Transfer Learning

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Genomics, Proteomics & Bioinformatics 2024年第2期22卷 157-170页

作者： Shan-Ju Yeh Shreya Paithankar Ruoqiao Chen jing xing Mengying Sun Ke Liu Jiayu Zhou Bin Chen Department of Pediatrics and Human Development Michigan State UniversityGrand RapidsMI 49503USA Department of Pharmacology and Toxicology Michigan State UniversityGrand RapidsMI 49503USA Department of Computer Science and Engineering Michigan State UniversityEast LansingMI 48824USA

Gene expression profiling of new or modified cell lines becomes routine today;however,obtaining comprehensive molecular characterization and cellular responses for a variety of cell lines,including those derived from underrepresented groups,is not trivial when resources are *** gene expression to predict other measurements has been actively explored;however,systematic investigation of its predictive power in various measurements has not been well ***,we evaluated commonly used machine learning methods and presented TransCell,a two-step deep transfer learning framework that utilized the knowledge derived from pan-cancer tumor samples to predict molecular features and *** these models,TransCell had the best performance in predicting metabolite,gene effect score(or genetic dependency),and drug sensitivity,and had comparable performance in predicting mutation,copy number variation,and protein ***,TransCell improved the performance by over 50%in drug sensitivity prediction and achieved a correlation of 0.7 in gene effect score ***,predicted drug sensitivities revealed potential repurposing candidates for new 100 pediatric cancer cell lines,and predicted gene effect scores reflected BRAF resistance in melanoma cell ***,we investigated the predictive power of gene expression in six molecular measurement types and developed a web portal(http://***/transcell/)that enables the prediction of 352,000 genomic and cellular response features solely from gene expression profiles.

关键词： Genomics Transcriptomics Cancer dependency Drug repurposing Transfer learning

Ionic liquid modified GC electrode for the direct electrochemistry of chloroperoxidase

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Chinese Chemical Letters 2008年第12期19卷 1483-1486页

作者： Liu Yang Xia Qin Wu Rong Wang Zhong Qing Lu Wen jing Hou He xing Li Life and Environment Science College Shanghai Normal University 100 Guilin Road Shanghai 200234 PR China

Chloropcroxidase （CPO） was immobilized by konjac glucomannan （KGM） on the 1-butyl-3-methyl imidazolium tetrafluoroborate [BMIM][BF4]/Nafion modified glassy carbon eloctrode. The electrochemical behaviors of the immobilized CPO were investigated by cyclic voltammetry. The results showed that CPO was successfully immobilized on the GCE and underwent fast direct electron transfer reactions with the formal potential at -0.3 V vs. SCE. The modified electrode showed a good catalytic activity for elcctrocatalytical reduction of O2 and H2O2.

关键词： Ionic liquid Chloroperoxidase Electroeatalysis Direct electrochemistry

Strategy to boost hydrolysis resistance and stabilize low infrared emissivity of ZrB_(2) via nanoscale LaF_(3) surface modification

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Rare Metals 2022年第12期41卷 4164-4175页

作者： Xue-jing xing Xian Jian Lin-Bo Zhang Hai-Peng Lu Zhong-Wei Zhang Simeon Agathopoulos Liang-Jun Yin Long-Jiang Deng School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China The Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001China National Engineering Research Center of Electromagnetic Radiation Control Materials University of Electronic Science and Technology of ChinaChengdu 611731China Laboratory of Energy Storage and New Energy Materials Technology Central Research InstituteDongfang Electric CorporationChengdu 611731China Department of Materials Science and Engineering University of Ioanninaloannina 45110Greece

Owing to its excellent high-temperature resistance and high conductivity,zirconium diboride(ZrB_(2)) has been applied as an infrared suppression ***,ZrB_(2)is susceptible to hydrolysis under high-moisture conditions and even under mild working *** improvement in the hydrophobicity of the ZrB_(2)surface effectively reduces wetting by water and suppresses hydrolysis reaction,particularly under high-temperature and high-moisture ***,we report a novel,easy,and highly reproducible method for producing a fully coated ZrB_(2)surface by developing a nanoscale hydrophobic layer of glassy LaF_(3)on the surface of ZrB_(2)powder particles in situ(i.e.,during the carbothermal synthesis of ZrB_(2)).Through the tests carried out at 200 ℃for 100-300 h in a hydrothermal reactor,the produced powders displayed remarkably high long-term hydrolysis resistance and pronounced chemical *** with treated ZrB_(2),ZrB_(2)@LaF_(3)remained lower infrared emissivity when continuously intensifying hydrolyzation *** results suggest that a nanoscale surface modification strategy can be applied to stabilize the infrared emissivity of ZrB_(2)in a water-oxygen coupling environment.

关键词： ZrB_(2) LaF_(3) Carbothermal reaction Hydrolysis resistance Hydrophobic behavior

Synthesis of novel chiral N,P-containing multidentate ligands and their applications in asymmetric transfer hydrogenation

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Chinese Chemical Letters 2011年第11期22卷 1269-1272页

作者： Shen Luan Yu Yan Yun Li Zhen Rong Dong Juan Ni Zhang Qi Li jing xing Gao State Key Laboratory of Physical Chemistry of Solid Surfaces National Engineering Laboratory for Green ChemicalProductions of Alcohols-Ethers-Esters and Department of Chemistry College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China

Novel chiral PN_4-type multidentate aminophosphine ligands have been successfully synthesized by Schiff-base condensation of bis（o-formylphenyl）phenylphosphane and various chiral *** structures were fully characterized by IR,EI-MS and *** catalytic systems,prepared in situ from the multidentate ligands and iridium（I） complexes,showed high activity in asymmetric transfer hydrogenation of propiophenone in 2-propanol solution,leading to corresponding optical alcohol with up to 75%ee.

关键词： Chiral multidentate aminophosphine ligand Iridium complex Propiophenone Asymmetric transfer hydrogenation

Background Removal Based on Significant Contour Tracking and Segmentation

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Background Removal Based on Significant Contour Tracking and...

Cluster of differentiation antigens:essential roles in the identification of teleost fish T lymphocytes

作者： jing xing School of Intelligent Science ＆ Information Engineering Xi’an Peihua University

The grabcut algorithm is known to use the graph theory to cluster pixels for background removal, however, it is disadvantageous that the mark is needed to identify foreground and background. To automate this process, a method is proposed which is consist of three parts. First the edge detection with max pooling is used to get foreground edges, and then to get the object-level contours, a significant contour tracking algorithm is used. When the relative precise contour is obtained, an algorithm fusing morphological operation and grabcut is applied to get the exact segmentation.

关键词： Max pooling grabcut background removal morphology transformation

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Marine Life Science & Technology 2022年第3期4卷 303-316页

作者： Hong‑fei Tian jing xing Xiao‑qian Tang Heng Chi Xiu‑zhen Sheng Wen‑bin Zhan Laboratory of Pathology and Immunology of Aquatic Animals KLMMEFisheries CollegeOcean University of ChinaQingdao 266003China Laboratory for Marine Fisheries Science and Food Production Processes Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China

Cluster of differentiation(CD)antigens are cell surface molecules expressed on leukocytes and other cells associated with the immune *** that react with CD antigens are known to be one of the most essential tools for identifying leukocyte subpopulations.T lymphocytes,as an important population of leukocytes,play essential roles in the adaptive immune *** of the CD antigens expressed on T lymphocytes are used as surface markers for T lymphocyte classification,including CD3,CD4 and CD8 *** this review,we summarize the recent advances in the identification of CD molecules on T lymphocytes in teleosts,with emphasis on the functions of CD markers in the classification of T lymphocyte *** notice that genes encoding CD3,co-receptors CD4 and CD8 have been cloned in several fish species and antibodies have been developed to study protein expression in morphological and functional contexts.T lymphocytes can be divided into CD4^(+)and CD8^(+)cells discriminated by the expression of CD4 and CD8 molecules in teleost,which are functionally similar to mammalian helper T cells(Th)and cytotoxic T cells(Tc),*** studies are still needed on the particular characteristics of teleost T cell repertoires and adaptive responses,and results will facilitate the health management and development of vaccines for fish.

关键词： T lymphocytes Surface marker Classification Monoclonal antibody Fish

The Molecular Mechanism of Xinyi San for the Treatment of Senile Rhinitis Based on Network Pharmacology

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Journal of Biosciences and Medicines 2022年第8期10卷 110-121页

作者： jing xing Lingdi Wang Department of Pharmacy Affiliated Hospital of Chengde Medical College Chengde China

Objective: To study the molecular mechanism of Xinyi San for the treatment of senile rhinitis by applying network pharmacological analysis technology. Methods: The effective components and corresponding targets of Xinyi San were collected by TCMSP. The targets of senile rhinitis were collected by the Genecards database. The potential target of Xinyi San in the treatment of senile rhinitis was obtained by Venn analysis. Cytoscape 3.7.2 the software constructs the relationship network model of “disease-single drug-active ingredient-action target”. Protein protein interaction (PPI) network was constructed by using a string database. R4.1.1 software was used for GO function enrichment analysis and KEGG pathway enrichment analysis. Results: In this study, we obtained 158 active ingredients, 40 potential therapeutic targets, 74 GO projects, and 99 pathways. Major pathways include Lipid and atherosclerosis, Chemical carcinogenesis-receptor activation, PI3K-Akt signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways of neurodegeneration-multiple diseases, etc. Conclusion: Xinyi San has the characteristics of multi-component, multi-target, and multi-channel in the treatment of senile rhinitis. This study provides a basis for the in-depth study of Xinyi San.

关键词： Network Pharmacology Senile Rhinitis Xinyi San Molecular Mechanism

The Relationship between College Students’ Online Game Addiction, Family Function and Self-Control

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Health 2021年第9期13卷 910-919页

作者： Xihua Zhou jing xing School of Education Baoji University of Arts and Sciences Baoji China

Objective: To study the status of online game addiction, self-control ability and family function, analyze the influence factors and the relationship between them. Methods: The questionnaire of online game addiction, family function and self-control ability was used to investigate some college students. Results: 1) The detection rate of college students’ online game addiction is 40%. There are significant differences in sex, grade and only child in online game addiction. 2) There are significant differences in self-control ability and family function between online game addicts and non-addicts. 3) Self-control ability and family function have a significant predictive effect on online game addiction. Conclusion: College students’ online game addiction is affected by their self-control ability and family function, and it can be alleviated by improving their self-control ability and family function.

关键词： College Students Online Game Addiction Family Function Self-Control