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Effect of moxibustion on survival status and nutritional metabolic factor in tumor-bearing rats with gastric cancer

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World Journal of Acupuncture-Moxibustion 2019年第3期29卷 210-215页

作者： Zhuojun PENG jing tan Yupan CHEN Huan ZHAO Junlin SHI Yaping LIN School of Acupuncture-Moxibustion Hunan University of Chinese MedicineChangsha 410208China First-Class Discipline of Chinese medicine in Hunan University of Chinese Medicine Changsha 410208China

Objective:To observe the effect of moxibustion on the survival status and nutritional metabolic factors of tumor-bearing rats with gastric cancer and explore the inhibitory effect of moxibustion on the tumorbearing ***:A total of 40 SD rats were randomly divided into a blank group,a sham-operated group,a model group and a moxibustion group,10 rats in each *** cancer models were established in the model group and the moxibustion *** rats of all the groups underwent the same constraining procedure for 20 min every ***,moxibustion was applied at acupoints for 20 min in the rats of the moxibustion *** were two groups of *** group included"Zusanli(足三里ST 36)""Zhongwan(中脘CV12)"and"Guanyuan(关元CV4)".The other group included bilateral"Pishu(脾俞BL 20)"and"Weishu(胃俞BL 21)".Moxibustion was applied for 20 min every day at the acupoints of the two groups alternatively and lasted for 14 *** survival status of rats was observed and the score of survival status and body weight of rats were recorded every *** the end of intervention,the orbital blood was collected and the rats were sacrificed for sample *** viscera-free body weight was *** biochemical analyzer,the blood glucose(GLU),albumin(ALB),total protein(TP)and triglyceride(TG)in serum were ***:(1)Regarding the score of the survival status,after modeling,the scores in the model group and the moxibustion group were all higher than those of the sham-operation group(both P<0.05).After intervention,the score in the moxibustion group was lower than that of the model group(P<0.05).(2)After modeling,the body weight in the moxibustion group and the model group was lower than those of the blank group,indicating a statistical significance(both P<0.05).The body weight in the moxibustion group was higher than that of the model group after intervention,indicating the statistical significance(P<0.05).(3)Regarding the viscera-free body weight,it wa

关键词： Moxibustion Tumor-bearing rats with gastric cancer Survival status Blood glucose(GLU) Albumin(ALB) Total protein(TP) Triglyceride(TG) Viscera-free weight

Characteristics of run off and sediment generation of forest vegetationon a hill slope by use of artificial rainfall apparatus

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Journal of Forestry Research 2012年第3期23卷 419-424页

作者： LI Xiang NIU Jian-zhi LI Jiao XIE Bao-yuan HAN Yi-ni tan jing-ping ZHANG Ying-hu Key Laboratory of Soil and Water Conservation&Desertification Combating Beijing Forestry UniversityBeijing 100083China

We studied the impact of forest vegetation on soil erosion, surface runoff, and sediment generation by using field simulated rainfall apparatus. We measured runoff and sediment generation of five 4.5 × 2.1 m runoff plots （a bare soil as a control; two Pinus tabulaeformis forest plots and two Platycladus orientalis forest with row spacing of 1 m × 1 m and 1.5 m× 1.5 m, respectively） in Beijing Jiu Feng National Forest Park under three rainfall intensities （0.42, 0.83, 1.26 mm per minute）. Forest vegetation significantly reduced soil erosion and sediment yield. Mean total runoff volume in the four tree stand plots was 93% of that in the control plot, demonstrating the limited effectiveness of forest vegeta- tion in runoff control. With increasing rainfall intensity, runoff reduction in forest plots declined from 28.32% to 2.1%. Similar trends in runoff coefficient and the relationship between runoffvolume and rainfall duration was observed. Mean total sediment yield and mean sediment yield reduction rate under different treatments was 55.05% and 43.17% of those in the bare soil control plot, respectively. Rainfall intensity played an important role in runoff and sediment generation processes, and had a greater impact on runoff than on soil erosion and sediment generation. When considering several factors in runoff and sediment transport processes, the P. tabulaeform plot with row spacing at 1 × 1 m had a greater effect on soil and water conservation than did other forested plots.

关键词： soil erosion forest vegetation rainfall intensity runoff sediment

“利益分析”视角下的国家级新区空间形成机制——以赣江新区为例

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城市发展研究 2019年第8期26卷 118-124页

作者：谭静中国城市规划设计研究院绿色所

国家级新区在打破原有行政区域组建的同时经历了行政关系网络的剧烈变化,这种变化对于新区的空间格局形成有着至关重要的影响。研究从"利益分析"的视角,对赣江新区成立和建设初期新区管委会和江西省、南昌市以及新区下辖组团等多级行政... 详细信息

国家级新区在打破原有行政区域组建的同时经历了行政关系网络的剧烈变化,这种变化对于新区的空间格局形成有着至关重要的影响。研究从"利益分析"的视角,对赣江新区成立和建设初期新区管委会和江西省、南昌市以及新区下辖组团等多级行政组织在围绕区域重大基础设施布局、新区一体化空间格局构建等重大决策上发生的利益互动展开具体而细致的分析,并指出规划作为重要的利益分配机制和利益协商平台,应充分发挥保障多元价值观下的公共利益、保障多方推进下的整体利益、协调和兼顾局部利益、衔接近远期利益等作用。

关键词：行政组织关系利益观念利益互动空间格局

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设计驱动乡村文旅融合创新发展策略研究

经济问题 2023年第9期 98-105页

作者：谭静山西财经大学文化旅游与新闻艺术学院山西太原030006

在当前全面推进乡村振兴的背景下,历史文化遗迹的保护利用和全面规划对于乡村文旅融合创新发展意义重大。在此过程中,设计策略驱动乡村建设,其基本范式应当首先服务地方村民和传承地域文化,跟乡村发生紧密关系并形成可持续的文旅资源,... 详细信息

在当前全面推进乡村振兴的背景下,历史文化遗迹的保护利用和全面规划对于乡村文旅融合创新发展意义重大。在此过程中,设计策略驱动乡村建设,其基本范式应当首先服务地方村民和传承地域文化,跟乡村发生紧密关系并形成可持续的文旅资源,从而催生乡村经济发展的内生动力,其策略本质是旅游消费对于乡村异质文化的挖掘与融入。山西芮城广仁王庙(俗称五龙庙)的开发个案展现出当设计策略介入历史文化遗存进行文旅开发时,要从传播策略、本土资源转化、乡村生态共生、文旅消费异质化特征等多方面着手,关注当地村落的社会、历史、文化、经济等多层面生态性关联,尤其要处理好文化遗存的保护与地方性、历史性知识的延续关系。

关键词：设计驱动乡村建设文旅融合创新发展文旅经济广仁王庙

仪式神像画所有权及使用资格的获得——基于蓝山瑶族勉瑶支系仪式的观察

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民族艺术 2019年第2期 121-127,146页

作者：谭静广西民族大学民族学与社会学学院

湖南省永州市蓝山县的瑶族师公通过“挂三灯”仪式获得拥有和使用“行司”神像画的资格,又通过“度戒”仪式,进一步获得“大堂”神像画的所有权及使用资格,“挂三灯”和“度戒”仪式中被传授的法术和能力是其获得神像画所有权及使用资... 详细信息

湖南省永州市蓝山县的瑶族师公通过“挂三灯”仪式获得拥有和使用“行司”神像画的资格,又通过“度戒”仪式,进一步获得“大堂”神像画的所有权及使用资格,“挂三灯”和“度戒”仪式中被传授的法术和能力是其获得神像画所有权及使用资格的基础条件。上下两坛兵马的授予是获得所有权及使用资格的关键所在。反过来,仪式神像画则成为师公地位和能力的标志,其数量的多寡、等级的高低与师公掌握的法术和能力的高低、可操控阴兵数量的多少成正比。

关键词：瑶族瑶族神像仪式神像画挂三灯度戒

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社会组织资产管理问题研究

中央财经大学学报 2019年第10期 106-118页

作者：谭静中国财政科学研究院公共资产研究中心

以“多元共治”为核心的现代化国家治理要求社会组织发挥更大作用,而加强社会组织资产管理是这一作用发挥的基本保障。我国社会组织资产管理主要是以政府为主体的外部管理和以社会组织为主体的内部管理,但存在资产管理制度未建立、资产... 详细信息

以“多元共治”为核心的现代化国家治理要求社会组织发挥更大作用,而加强社会组织资产管理是这一作用发挥的基本保障。我国社会组织资产管理主要是以政府为主体的外部管理和以社会组织为主体的内部管理,但存在资产管理制度未建立、资产产权管理混乱、财务会计制度不完善、信息披露透明度低等问题亟需解决。因此,应探索构建“政府部门综合管理、社会组织依法运营、各方力量共同监督”的社会组织资产管理体制,建立围绕社会组织资产全生命周期和防范国有资产流失的“审查管理、产权管理、规范管理、监督管理、剩余财产管理、国有资产管理”管理体系,聚焦难点症结,发力施策。

关键词：社会组织资产管理现状问题全生命周期产权管理

Auricular therapy for chemotherapy-induced nausea and vomiting in cancer patients:Perspectives from the traditional zang-fu organs and meridians theory

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TMR Integrative Nursing 2020年第5期4卷 149-155页

作者： jing-Yu tan Lorna KPSuen Tao Wang The Hong Kong Polytechnic University School of NursingHung HomKowloonHong KongChina SAR Charles Darwin University College of Nursing and Midwifery Brisbane CentreLevel 11410 Ann StreetBrisbaneQLD 4000Australia.

This paper presents the theoretical background of using auricular therapy(AT)for managing chemotherapy-induced nausea and vomiting(CINV)from the perspectives of traditional zang-fu organs and meridian *** zang-fu organs of stomach,spleen and liver play a crucial role in regulating the gastrointestinal *** chemotherapeutic agents can significantly impede the gastrointestinal functions and subsequently contribute to various gastrointestinal symptoms including nausea and *** of the stomach,spleen and liver can correspond to specific auricular acupoints,while by stimulating those acupoints,the chaotic Qi movement can be reversed to its normal status,and the hyperactivities of the gastrointestinal system can also be alleviated to reduce the CINV *** studies based on such theory have well supported the effects of AT on ***,relationships between the traditional theory and the modern medicine understanding of the CINV mechanisms remain unknown and should be further explored in future research.

关键词： Auricular therapy Nausea and vomiting Chemotherapy Neoplasms Medicine Chinese traditional

Myricetin protects against lipopolysaccharide-induced disseminated intravascular coagulation by anti-inflammatory and anticoagulation effect

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Asian Pacific Journal of Tropical Medicine 2018年第3期11卷 255-259页

作者： jing-Yi tan Xue-Qin Chen Bi-Jun Kang Zi-Xi Qin Jia-Hong Chen Ren-Dong Hu Liang-Cai Wu Pharmacology Department of Basic Medical Sciences School of Medicine Jinan University The 6th Affiliated Hospital.Sun Yat-sen University

Objective: To explore the therapeutic effect and mechanism of myricctin on disseminated intravascular coagulation(DIC). Methods: The DIC model was established by injection of60 mg/kg LPS in KM mice, and the treatment groups were injected myricetin with different concentrations(25 or 50 mg/kg) 30 min before the model was established. Both coagulation indicators and organ function were tested, including PT, APTT, fibrinogen. AST, ALT. BUN and tissue section. In vitro, the inflammatory model of RAW 264.7 macrophage cells were established by 10 μg/mL LPS. The treatment group was treated with 50 μmol/mL myricetin for 30 min before LPS, and the expression of TNF-a and p-NF-KB was detected, further to explore the therapeutic mechanism. Results: LPS-induced DIC led to a reduction of fibrinogen and a rise of PT, APTT,AST, ALT, BUN levels, but the treatment of myricctin significantly inhibited these abnormalities. Histopathology analysis also revealed that myricetin remarkably protected the liver and renal damage. In vitro, the expression of TNF-α and p-NF-κB induced by LPS was repressed by myricetin. Conclusions: This study provides new insights into the protective effects of myricetin in LPS-induced DIC by anticoagulant and anti-inflammatory via suppressing the activation of p-NF-κB which decreased TNF-α level.

关键词： Myricetin Lipopolysaccharide Disseminated intravascular coagulation Anti-inflammatory Macrophages

Prohibitin(PHB)interacts with AKT in mitochondria to coordinately modulate sperm motility

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Asian Journal of Andrology 2020年第6期22卷 583-589页

作者： Xiao-Hui Li Ran-Ran Chai Guo-Wu Chen Ling-Fei Zhang Wen-jing tan-Tai Hui-Juan Shi Patricia A Martin-DeLeon Wai-Sum O Hong Chen Department of Anatomy Histology and EmbryologyKey Laboratory of Medical Imaging Computing and Computer Assisted Intervention of ShanghaiSchool of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Ji'Ai Genetics and IVF Institute Obstetrics and Gynecology HospitalInstitute of Reproduction and DevelopmentFudan UniversityShanghai 200011China Key Lab of Reproduction Regulation of NPFPC-Shanghai Institute of Planned Parenthood Research Fudan University Reproduction and Development InstitutionShanghai 200032China Department of Biological Sciences University of DelawareNewarkDE 19716-2590USA School of Biomedical Sciences The University of Hong KongHong Kong SARChina

Prohibitin(PHB),an evoluti on arily con served mitochondrial inner membra ne protein,is highly expressed in cells that require strong mitoch on drial ***,we dem on strated that the deleti on of Phb in spermatocytes results in impaired mitochondrial *** addition,PHB expression in the mitochondrial sheath of human sperm has a significantly negative correlation with mitochondrial reactive oxygen species levels,but a positive one with mitochondrial membrane potential and sperm *** results suggest that mitochondrial PHB expression plays a role in sperm ***,the mechanism of PHB-mediated regulation of sperm motility remai ns unk ***,we dem on strate for the first time that PHB interacts with protei n kinase B(AKT)and exists in a complex with phospho-PHB(pT258)and phospho-AKT in the mitochondrial sheath of murine sperm,as determined using colocalization and coimmunoprecipitation *** blocking AKT activity using wortmannin(a phosphatidylinositol 3-kinase[PI3K]inhibitor),murine sperm have significantly(P<0.05)decreased levels of phospho-PHB(pT258)and the total and progressive ***,significantly(P<0.05)lower levels of phospho-PI3K P85 subunit a+γ(pY199 and pY46)and phospho-AKT(pS473;pT308)are found in sperm from infertile asthenospermic and oligoasthenospermic men compared with no rmospermic subjects,which suggest a reduced activity of the PI3K/AKT pathway in these in fertile ***,these sperm from infertile subjects also have a significantly(P<0.05)lower level of phospho-PHB(pT258).Collectively,our findings suggest that the interaction of PHB with AKT in the mitochondrial sheath is critical for sperm motility,where PHB phosphorylation(pT258)level and PI3K/AKT activity are key regulatory factors.

关键词： male in fertility prohibitin(PHB) protein kinase B(AKT) sperm motility