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A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

Signal Transduction and Targeted Therapy 2021年第3期6卷 779-794页

作者： Kang Sun Yi-yuan Li jin jin MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences InstituteZhejiang UniversityHangzhou 310058China Key Laboratory for Developmental Genes and Human Disease Ministry of EducationInstitute of Life SciencesJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjing 210096China Sir Run Run Shaw Hospital College of Medicine Zhejiang UniversityHangzhou 310016China

The response of immune cells in cardiac injury is divided into three continuous phases:inflammation,proliferation and *** kinetics of the inflammatory and proliferation phases directly influence the tissue *** cardiac homeostasis,cardiac tissue resident macrophages(cTMs)phagocytose bacteria and apoptotic ***,NK cells prevent the maturation and transport of inflammatory *** cardiac injury,cTMs phagocytose the dead cardiomyocytes(CMs),regulate the proliferation and angiogenesis of cardiac progenitor *** cells prevent the cardiac fibrosis,and promote vascularization and *** 1 macrophages trigger the cardioprotective responses and promote tissue fibrosis in the early ***,type 2 macrophages promote cardiac remodeling and angiogenesis in the late *** macrophages and neutrophils firstly lead to chronic inflammation by secreting proinflammatory cytokines,and then release anti-inflammatory cytokines and growth factors,which regulate cardiac *** this process,dendritic cells(DCs)mediate the regulation of monocyte and macrophage *** eosinophils and Mast cells(MCs)release some mediators which contribute to coronary vasoconstriction,leukocyte recruitment,formation of new blood vessels,scar *** adaptive immunity,effector T cells,especially Th17 cells,lead to the pathogenesis of cardiac fibrosis,including the distal fibrosis and scar *** protectors,Treg cells,inhibit reduce the inflammatory response,then directly trigger the regeneration of local progenitor cell via IL-10.B cells reduce myocardial injury by preserving cardiac function during the resolution of inflammation.

关键词： cardiac homeostasis inflammation

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Control structure comparison for three-product Petlyuk column

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Chinese Journal of Chemical Engineering 2018年第8期26卷 1621-1630页

作者： Shengkun Jia Xing qian Xigang yuan Sigurd Skogestad School of Chemical Engineering and Technology Chemical Engineering Research Center Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)State Key Laboratory of Chemical Engineering Tianjin University Department of Chemical Engineering Norwegian University of Science and Technology (NTNU)

The focus of this paper is to investigate different control structures(single-loop PI control) for a dividing wall(Petlyuk) column for separating ethanol, n-propanol and n-butanol. Four control structures are studied. All the results are simulations based on Aspen Plus. Control structure 1(CS1) is stabilizing control structure with only temperature controllers. CS2, CS3 and CS4, containing also composition controllers, are introduced to reduce the steady state composition deviations. CS2 adds a distillate composition controller(CCDB) on top of CS1. CS3 is much more complicated with three temperature-composition cascade controllers and in addition a selector to the reboiler duty to control the maximum controller output of light impurity composition control in side stream and bottom impurity control in the prefractionator. CS4 adds another high selector to control the light impurity in the sidestream. Surprisingly, when considering the dynamic and even steady state performance of the proposed control structures, CS1 proves to be the best control structure to handle feed disturbances inserted into the three-product Petlyuk column.

关键词： Distillation columns Automatic process control Computer-aided control system design Petlyuk columns

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HRRP target recognition based on kernel joint discriminant analysis

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Journal of Systems Engineering and Electronics 2019年第4期30卷 703-708页

作者： LIU Wenbo yuan Jiawen ZHANG Gong SHEN qian College of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China

With the improvement of radar resolution,the dimension of the high resolution range profile(HRRP)has *** order to solve the small sample problem caused by the increase of HRRP dimension,an algorithm based on kernel joint discriminant analysis(KJDA)is *** with the traditional feature extraction methods,KJDA possesses stronger discriminative ability in the kernel feature space.K-nearest neighbor(KNN)and kernel support vector machine(KSVM)are applied as feature classifiers to verify the classification *** results on the measured aircraft datasets show that KJDA can reduce the dimensionality,and improve target recognition performance.

关键词： high resolution range profile(HRRP) target recognition small sample problem feature extraction dimension reduction

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An updated megaphylogeny of plants,a tool for generating plant phylogenies and an analysis of phylogenetic community structure

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Journal of Plant Ecology 2016年第2期9卷 233-239页

作者： Hong qian Yi jin Research and Collections Center Illinois State Museum1011 East Ash StreetSpringfieldIL 62703USA College of Life Sciences Zhejiang UniversityHangzhou 310058China

Aims The aim of this article is ***,we present an updated version of a published megaphylogeny of vascular plants that can be used in studies of plant ecology and ***,we develop a tool that can be used by botanists and plant ecologists to generate phylogenetic hypotheses in three ***,we use a set of regional assemblages of angiosperm trees in North america as a model system to evaluate the effect of differences in phylogenies generated using the three scenarios on the quantification of phylogenetic properties and the relationship between measures of phylogenetic properties and *** The taxonomy and nomenclature of plant species in the megaphy-logeny were standardized according to The Plant list(version 1.1).a tool for generating phylogenies was created using the r *** robustness of derived phylogenies was evaluated using correlation and regression *** Findingsan updated megaphylogeny of vascular plants(PhytoPhylo)and a tool for reconstructing phylogenies of seed plants(***)were *** study shows that phylogenies generated by *** using the PhytoPhylo megaphylogeny as a backbone are nearly as good as phylogeny resolved at the species level when using derived phylogenies to quantify phylogenetic properties(*** diversity and phylogenetic relatedness)of biological assemblages,and that ***-generated phylogenies are robust for studies of community ecology and biogeography,par-ticularly those seeking for patterns of phylogenetic properties along environmental gradients.

关键词： megatree megaphylogeny phylogenetic community ecology phylogenetic metrics phylogenetic tree supertree vascular plants

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Study on co-cracking performance of different hydrocarbon mixture in a steam pyrolysis furnace

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Chinese Journal of Chemical Engineering 2016年第9期24卷 1252-1262页

作者： Benfeng yuan jinlong Li Wenli Du Feng qian Key Laboratory of Advanced Control and Optimization for Chemical Processes Ministry of Education East China University of Science and Technology School of Information Science and Technology East China University of Science and Technology

Co-cracking is a process where the mixtures of different hydrocarbon feedstocks are cracked in a steam pyrolysis furnace, and widely adopted in chemical industries. In this work, the simulations of the co-cracking of ethane and propane, and LPG and naphtha mixtures have been conducted, and the software packages of COILSIM1 D and Sim CO are used to account for the cracking process in a tube reactor. The effects of the mixing ratio, coil outlet temperature, and pressure on cracking performance have been discussed in detail. The co-cracking of ethane and propane mixture leads to a lower profitability than the cracking of single ethane or single propane. For naphtha, cracking with LPG leads to a higher profitability than single cracking of naphtha, and more LPG can produce a higher profitability.

关键词： Co-cracking Mixing ratio Coil outlet temperature(COT) Coil outlet pressure(COP) Pyrolysis furnace

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TOWARDS EXPLORING WHEN AND WHAT PEOPLE REVIEWED FOR THEIR ONLINE SHOPPING EXPERIENCES

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Journal of Systems Science and Systems Engineering 2018年第3期27卷 367-393页

作者： Liangqiang Li Hua yuan Yu qian Peiji Shao School of Management and Economics University of Electronic Science and Technology of China Chengdu 611731 China

Web 2.0 technologies have attracted an increasing number of people with various backgrounds to become active online writers and viewers. As a result, exploring reviewers＇ opinions from a huge number of online reviews has become more important and simultaneously more difficult than ever before. In this paper, we first present a methodological framework to study the ＂purchasing-reviewing＂ behavior dynamics of online customers. Then, we propose a review-to-aspect mapping method to explore reviewers＇ opinions from the massive and sparse online reviews. The analytical and experimental results with real data demonstrate that online customers can be sectioned into groups in accordance with their reviewing behaviors and that people within the same group may have similar reviewing motivations and concerns for an online shopping experience.

关键词： E-commerce online review review dynamics opinion mining

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Bounds on partial derivatives of NURBS surfaces

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Applied Mathematics(A Journal of Chinese Universities) 2017年第3期32卷 281-293页

作者： WANG Guo-jin XU Hui-xia HU qian-qian School of Mathematical Sciences Zhejiang University Institute of Mathematics Zhejiang Wanli University Department of Mathematics Zhejiang Gongshang University

In this paper, we estimate the partial derivative bounds for Non-Uniform Rational B-spline(NURBS) surfaces. Firstly, based on the formula of translating the product into sum of B-spline functions, discrete B-spline theory and Dir function, some derivative bounds on NURBS curves are provided. Then, the derivative bounds on the magnitudes of NURBS surfaces are proposed by regarding a rational surface as the locus of a rational curve. Finally, some numerical examples are provided to elucidate how tight the bounds are.

关键词： NURBS curve NURBS surface derivative bound Dir function discrete B-spline

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Influence of laser re-melting and vacuum heat treatment on plasma-sprayed FeCoCrNiAl alloy coatings

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Journal of Iron and Steel Research International 2017年第12期24卷 1199-1205页

作者： Dan-yang Lin Nan-nan Zhang Bin He Bing-qian jin Yue Zhang De-yuan Li Fu-yu Dong Department of Material Science and Engineering Shenyang University of Technology Department of Pipeline Shenyang Institute of Special Equipment Inspection & Research

FeCoCrNiAl high entropy alloy coatings were prepared by supersonic air-plasma *** coatings were post-treated by vacuum heat treatment at 600 and 900°C,and laser re-melting with 300 W,respectively,to study the influence of different treatments on the structure and properties of the *** phase constitution,microstructure and microhardness of the coatings after treatments were investigated using X-ray diffraction,scanning electron microscopy and energy dispersive *** showed that the as-sprayed coatings consisted of pure metal and *** AlNi;phase was obtained after the vacuum heat treatment process.A body-centered cubic structure with less AlNi;could be found in the coating after the laser re-melting *** average hardness values of the as-sprayed coating and the coatings with two different temperature vacuum heat treatments and with laser re-melting were 177,227,266 and 682 HV,*** suggests that the vacuum heat treatment promoted the alloying process of the coatings,and contributed to the enhancement of the coating wear *** laser re-melted coating showed the best wear resistance.

关键词： Plasma spray High entropy alloy Vacuum heat treatment Laser re-melting FeCoCrNiAl alloy coating

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Phase Diagram of the 2-Dimensional Ising Model with Dipolar Interaction

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Chinese Physics Letters 2001年第4期18卷 491-494页

作者： SUN Gang CHU qian-jin Institute of Physics Chinese Academy of SciencesBeijing 100080

We treat the 2-dimensional Ising model with the dipolar interaction by the numerical calculation under the restriction that the spin configurations are distributed with a 4 × 4 *** phase diagram with respect to temperature and dipolar interaction strength is *** characters of the phase diagram are consistent with those obtained in the references by the Monte Carlo simulation,except that we find a new rectangle phase,which is ordered in the spin structure with the 1 × 2 rectangle.

关键词： strength diagram phase

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Guaranteed Cost Attitude Tracking Control for Uncertain Quadrotor Unmanned Aerial Vehicle Under Safety Constraints

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1447-1457页

作者： qian Ma Peng jin Frank L.Lewis School of Automation Nanjing University of Science and TechnologyNanjing 210094China UTA Research Institute University of Texas at ArlingtonFort WorthTexas 76118 USA IEEE

In this paper,guaranteed cost attitude tracking con-trol for uncertain quadrotor unmanned aerial vehicle(QUAV)under safety constraints is ***,an augmented system is constructed by the tracking error system and reference *** transformation aims to convert the tracking control prob-lem into a stabilization control ***,control barrier function and disturbance attenuation function are designed to characterize the violations of safety constraints and tolerance of uncertain disturbances,and they are incorporated into the reward function as penalty *** on the modified reward function,the problem is simplified as the optimal regulation problem of the nominal augmented system,and a new Hamilton-Jacobi-Bellman equation is ***,critic-only rein-forcement learning algorithm with a concurrent learning tech-nique is employed to solve the Hamilton-Jacobi-Bellman equa-tion and obtain the optimal *** proposed algorithm can not only ensure the reward function within an upper bound in the presence of uncertain disturbances,but also enforce safety *** performance of the algorithm is evaluated by the numerical simulation.

关键词： Attitude tracking control quadrotor unmanned aerial vehicle(QUAV) reinforcement learning safety constraints uncertain disturbances.

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