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Preventive effects of Bifidobacterium lactis Probio-M8 on ovalbumin-induced food allergy in mice

Food Science and Human Wellness 2024年第4期13卷 2346-2352页

作者： Jialu Shi Yan Xu Cheng liu Shizhi wang jin wang Vijaya Raghavan Key Laboratory of Environmental Medicine and Engineering Ministry of Educationand Department of Nutrition and Food HygieneSchool of Public HealthSoutheast UniversityNanjing 210009China Department of Bioresource Engineering Faculty of Agricultural and Environmental SciencesMcGill UniversitySainte-Anne-de-BellevueQC H9X3V9Canada

Food allergy is a significant public health concern *** probiotics have been found to enhance food allergy by regulating immune-microbe interactions in animal models and ***,the effects of Bifidobacterium lactis Probio-M8 on food allergy have not been thoroughly *** present study examined the anti-allergic properties of Probio-M8,particularly in relation to immune response and gut microbiota *** demonstrate that oral administration of Probio-M8 effectively mitigated the allergy symptoms triggered by ovalbumin(OVA)by ameliorating the morphological damage in the jejunum,reducing OVA-specific IgE and histamine levels in the serum,and suppressing Th2 cytokines(interleukin(IL)4 and IL-13)while increasing Th1 cytokines(interferon(IFN)γ)and regulatory T(Treg)cytokines(IL-10 and transforming growth factor(TGF)β1)in the culture supernatants of splenic ***,Probio-M8 effectively altered the diversity and composition of gut microbiota,particularly the relative abundances of Akkermansia_muciniphila in OVA-induced *** to the OVA group,the Probio-M8 group showed a decrease in the relative abundance of Akkermansia_*** conclusion,Probio-M8 demonstrates the potential to alleviate food allergy by regulating the Th1/Th2 response and modulating gut microbiota,thereby offering a novel therapeutic strategy for patients with food allergy.

关键词： Food allergy Bifidobacterium lactis Probio-M8 T cell immune response Gut microbiota

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Effective integration of highly-efficient focusing apodized grating and quantum dots on a solid substrate for scalable quantum photonic circuits

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Science China(Physics,Mechanics & Astronomy) 2024年第9期67卷 99-107页

作者： Beimeng Yao Rongbin Su Shunfa liu Changkun Song Ying Yu jin liu Xuehua wang State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Optoelectronic Materials and Technologies School of Electronics and Information TechnologySun Yat-sen UniversityGuangzhou 510275China

Recent advancements in quantum photonic circuits have significantly influenced the field of quantum information *** pursuit of an integrated quantum photonic circuit that offers an active,stable platform for large-scale integration and high processing efficiency remains a key *** grating coupler,as a crucial element for an efficient transformation output interface in the integrated quantum photonic circuits,presents significant potential for practical ***,we demonstrate the integration block of a highly efficient shallow-etched focusing apodized grating coupler with indium arsenide(InAs)quantum dots(QDs)in gallium arsenide(GaAs)on a SiO2substrate for active quantum photonic *** designed grating couplers possess a high efficiency over 90% in the broadband(900-930 nm)from the circuit to free space,and a nearly-perfect match with the fiber ***,the efficiency to free space reaches 81.8%,and the match degree with the fiber mode is high up to 92.1%.The proposed integration block offers the potential for large-scale integration of active quantum photonic circuits due to its stable solid substrate and highly performant output for quantum measurements.

关键词： quantum dot grating coupler wafer bonding quantum photonic circuit

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Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1483-1493页

作者： jing jin Yurou wang Yueqin liu Subrata Chakrabarti Zhaoliang Su International Genome Center Jiangsu UniversityZhenjiang 212013China Institute for Medical Immunology Jiangsu UniversityZhenjiang 212013China Center Laboratory the Fourth People's Hospital of ZhenjiangZhenjiang 212008China Department of Pathology and Laboratory Medicine Western UniversityLondonOntario N6A 5C1Canada

Cardiac resident macrophages (CRMs) are the main population of cardiac immune cells. The role of these cells in regeneration, functional remodeling, and repair after cardiac injury is always the focus of research. However, in recent years, their dynamic changes and contributions in physiological states have a significant attention. CRMs have specific phenotypes and functions in different cardiac chambers or locations of the heart and at different stages. They further show specific differentiation and development processes. The present review will summarize the new progress about the spatiotemporal distribution, potential developmental regulation, and their roles in cardiac development and aging as well as the translational potential of CRMs on cardiac diseases. Of course, the research tools for CRMs, their respective advantages and disadvantages, and key issues on CRMs will further be discussed.

关键词： Cardiac resident macrophages Spatiotemporal distribution Cardiac development Cardiac homeostasis Physiological functions Research tools Clinical translation Transcriptional characteristics

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Enhanced plasticity of spontaneous coagulation cast oxide ceramic green bodies

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Journal of Advanced Ceramics 2024年第5期13卷 568-578页

作者： Juanjuan wang jin Zhao Junyan Mao Wenlong liu Haohao Ji Jian Zhang Shiwei wang State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

In the preparation of large-sized ceramics,the use of a green body with relatively high plasticity is crucial to minimize the risk of cracking during *** achieve this goal,glycerol and polyethylene glycol(PEG)were utilized as plasticizers in the shaping of green bodies of oxide ceramics through spontaneous coagulation casting(SCC).This study investigated the effects of plasticizers and particle sizes ranging from the submicron to nanoscale on the slurry viscosity,drying shrinkage of wet gels,and mechanical properties of green *** plasticity of the green bodies was assessed by measuring the impact toughness and flexural stress‒strain *** incorporating an appropriate plasticizer,the peak width of the flexural stress‒strain curve for dried green bodies from particles of different sizes was nearly twice that without plasticizers,and the impact toughness was enhanced by approximately 71%,34%,and 41%when the particle size decreased from the submicron scale to the nanoscale(0.45μm,0.18μm,and 50 nm,respectively).The drilling test revealed that there was nearly no cracking around the holes in the green bodies with *** plasticity mechanism of the green bodies was examined based on ultraviolet–visible(UV–Vis)spectroscopy and scanning electron microscopy(SEM).It was discovered that plasticizers might mitigate the brittleness of green bodies by adjusting the interactions between molecules and modifying the gel network properly.

关键词： green body plasticity plasticizer particle size impact toughness stress-strain curve

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Structural Stability of Natural Magnesiochromite at High-Temperature-Pressure Conditions

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Journal of Earth Science 2024年第4期35卷 1196-1203页

作者： Shuyu jin Xiang Wu Yungui liu Yanfei Zhang Chao wang State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan430074China College of Gems and Materials Hebei GEO UniversityShijiazhuang050031China

The podiform chromitites in the Luobusha ophiolite have been thought to experience a very deep formation,but the maximum depth is still an open ***,we have investigated the structural stability of natural magnesiochromite using the synchrotron-based powder X-ray diffraction and diamond anvil cells up to 48.6 GPa and 2450 *** results have shown that spinel-type magnesiochromite first decomposes into corundum-type‘Cr_(2)O_(3)’+B1-type‘MgO’at 11–14 GPa and 1250–1450 K,then modified ludwigite(mLd)-type‘Mg_(2)Cr_(2)O_(5)’+corundum-type‘Cr_(2)O_(3)’at 14.3–20.5 GPa and 1300–2000 K,and finally CaTi_(2)O_(4)-type phase at 24.5 *** the quenching procession from high-temperature-pressure conditions,the mLd-type phase appeared again and was kept at ambient *** also obtained the isothermal equation states of spinel-type and CaTi_(2)O_(4)-type phases,revealing the composition effect on their *** on the updated results,we propose chromitites could not experience pressure exceeding∼14.3 GPa(approximate maximum depth∼400 km)in the subduction-recycling genesis model.

关键词： chromite high-temperature and high-pressure phase transitions equation of state chromitites genesis

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Vulnerability assessment of UAV engine to laser based on improved shotline method

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Defence Technology（防务技术） 2024年第3期33卷 588-600页

作者： Le liu Chengyang Xu Changbin Zheng Sheng Cai Chunrui wang jin Guo Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China University of Chinese Academy of Sciences Beijing 100049China

Laser anti-drone technology is entering the sequence of actual combat,and it is necessary to consider the vulnerability of typical functional parts of *** the concept of"vulnerability"was proposed,a variety of analysis programs for battlefield targets to traditional weapons have been developed,but a comprehensive assessment methodology for targets'vulnerability to laser is still *** on the shotline method,this paper proposes a method that equates laser beam to shotline array,an efficient vulnerability analysis program of target to laser is established by this method,and the program includes the circuit board and the wire into the vulnerability analysis category,which improves the precision of the vulnerability *** the UAV engine part as the target of vulnerability analysis,combine with the"life-death unit method"to calculate the laser penetration rate of various materials of the UAV,and the influence of laser weapon system parameters and striking orientation on the killing probability is quantified after introducing the penetration rate into the vulnerability analysis *** quantitative analysis method proposed in this paper has certain general expansibility,which can provide a fresh idea for the vulnerability analysis of other targets to laser.

关键词： Laser weapon Laser damage Vulnerability UAV Engine Killing probability

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A clean disposal method of carbide slag with carbon emission reduction:Used as a flux for iron ore sintering Author links open overlay panel

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Particuology 2024年第8期91卷 303-314页

作者： Hanxiao Meng Jiankang wang Xiang liu Kelang jin Lei Zhang Hao Zhou State Key Laboratory of Clean Energy Utilization Institute for Thermal Power EngineeringZhejiang UniversityHangzhou310027China

Limestone or quicklime is a necessary flux in the iron ore sintering *** production and application process will cause CO_(2) emissions and various environmental pollution,but this has not attracted enough *** slag(CS)is a calcium-rich solid waste produced in acetylene production,the harmless disposal of which is still incomplete,resulting in soil and groundwater *** study investigated the granulation characteristics and sintering performance of the sintering mixture with different proportions of *** results show that replacing limestone with an appropriate proportion of CS is promising and beneficial to the formation of high-quality bonding *** CS accounts for 75%of the total mass of CS and limestone,the tumbler index increases by 8.10%and the comprehensive index decreases only from 100 to 96.16,which is within the acceptable *** application of CS in iron ore sintering can achieve a clean disposal of it and a considerable carbon emission reduction,as the main component of which is Ca(OH)2.

关键词： Ironore sintering Carbide slag Flux Carbon emission Comprehensive index

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Error Estimates of H^1-Galerkin Mixed Methods for the Viscoelasticity Wave Equation

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Chinese Quarterly Journal of Mathematics 2011年第1期26卷 131-137页

作者： wang jin-feng~,liu Yang~,LI Hong~（1. liu Yang LI Hong School of Statistics and Mathematics Inner Mongolia Finance and Economics CollegeHohhot 010051China School of Mathematical Sciences Inner Mongolia UniversityHohhot 010021China

H1-Galerkin mixed methods are proposed for viscoelasticity wave *** on the physical quantities of interest,two methods are *** optimal error estimates and the proof of the existence and uniqueness of semidiscrete solu... 详细信息

关键词： viscoelasticity wave equation H1-Galerkin mixed finite element methods existence and uniqueness optimal error estimates

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Personalized trajectory data perturbation algorithm based on quadtree indexing

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The Journal of China Universities of Posts and Telecommunications 2024年第4期31卷 17-27页

作者： liu Kun jin Junhui wang Hui Shen Zihao liu Peiqian School of Software Henan Polytechnic UniversityJiaozuo 454000China School of Computer Science and Technology Henan Polytechnic UniversityJiaozuo 454000China

To solve the privacy leakage problem of truck trajectories in intelligent logistics,this paper proposes a quadtreebased personalized joint location perturbation(QPJLP)algorithm using location generalization and local differential privacy(LDP)***,a flexible position encoding mechanism based on the spatial quadtree indexing is designed,and the length of the encoding can be adjusted freely according to data ***,to meet the privacy needs of different locations of users,location categories are introduced to classify locations as sensitive and ordinary ***,the truck invokes the corresponding mechanism in the QPJLP algorithm to locally perturb the code according to the location category,allowing the protection of non-sensitive locations to be reduced without weakening the protection of sensitive locations,thereby improving data *** experiments demonstrate that the proposed algorithm effectively meets the personalized trajectory privacy requirements while also exhibiting good performance in trajectory proportion estimation and top-k classification.

关键词： intelligent logistics quadtree indexing local differential privacy(LDP) trajectory privacy protection location categories

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Interface Design Strategy for GNS/AZ91 Composites with Semi-Coherent Structure

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Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 467-483页

作者： jing-Peng Xiong Yi-Qi Zeng jin-Long liu Wei-Cheng wang Lan Luo Yong liu Key Laboratory of Lightweight and High Strength Structural Materials of Jiangxi Province School of Advanced ManufacturingNanchang UniversityNanchang 330031China School of Physics and Materials Science Nanchang UniversityNanchang 330031China

The interfacial structure plays an important role in the mechanical properties of magnesium matrix composite(MMCs)reinforced with graphene nanosheet(GNS)due to their poor wettability with the Mg *** interface design strategy was proposed to form the semi-coherent interfacial structure with superior bonding *** lattice mismatch and interfacial bonding strength between Mg/rare earth oxide/carbon were utilized as key characteristics to evaluate the interfacial *** oxide(La2O3)was selected as the intermediate candidate due to its low lattice mismatch and high interfacial bonding *** identify the interfacial structure of Mg/La2O3/graphene,first-principles calculations were conducted to calculate the ideal work of separation and electronic structure of the *** demonstrated the presence of strong ionic and covalent interactions at the interface,which theoretically verified the strong interfacial bonding strength among Mg/La2O3/graphene *** experimentally validate the interface strength,MMCs with the interface structure of Mg/La2O3/GNS were *** formation of in-situ La2O3 led to the successful attainment of semi-coherent structures between Mg/La2O3 and La2O3/GNS,resulting in high strength and good ductility of the ***,this work proposes a new approach to interface design in MMCs with an enhancement of mechanical properties.

关键词： Interface design strategy Magnesium matrix composite Graphene nanosheets Semi-coherent interface Mechanical properties

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