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Developing a quantitative index system for assessing sustainable forestry management in Heilongjiang Province,China： a case study

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Journal of Forestry Research 2016年第3期27卷 611-619页

作者： jin-shan yang Feng-you Wang College of Forestry Northeast Forestry UniversityHarbin 150040 China Guizhou University for Nationalities Guiyang 550025 China Department of Forestry Forest Resources Management Service Harbin 150090 Heilongjiang Province China

In this study, we developed a comprehensive index system for forestry sustainability of Heilongjiang Province, which includes forest resources sustainability,sustainable economic development, sustainable social development and sustainable advancement in science and technology. Based on this system and the regional forest development, we further evaluated the sustainability of Heilongjiang Province for year 2008-2013. The results show that even though the regional forestry has been preliminarily on the track of sustainable development, it is fragile. Four indicators, e.g. soil and water retention rate,forest stand growth（per unit area）, the proportion of national investment and the annual carbon sequestration have important impact on the sustainability, with a weight of 39.0 % in all the indicators. We also analyzed the factors hindering the sustainable development. It turns out that soil and water retention rate, forest stand growth（per unit area）,the proportion of science and technology funds, per capita GDP and the proportion of the tertiary industry production are the main factors hindering regional sustainable development, which accounts for 50.94 % of the total obstacle degrees in the system. At last, we discussed how to promote the regional sustainable development from the perspectives of forest resources sustainability, economic development sustainability, society development sustainability and the sustainable advancement of science and technology.

关键词： Regional forestry Sustainable development Index system Empirical analysis

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Roles of Eph/ephrin bidirectional signaling during injury and recovery of the central nervous system

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Neural Regeneration Research 2018年第8期13卷 1313-1321页

作者： Yue Wan jin-shan yang Li-Cai Xu Xiao-Jiang Huang Wei Wang Min-Jie Xie Department of Neurology The Third People's Hospital of Hubei Province Wuhan Hubei Province China Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei ProvinceChina Department of Neurology First Affiliated Hospital Fujian Medical University Fuzhou Fujian Province China Department of Neurological Rehabilitation Center The Third People's Hospital of Hubei Province Wuhan Hubei Province China

Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce damage or improve functional recovery by merely targeting the molecular mechanisms of neuronal cell death after central nerve system injuries. Eph receptors and ephrin ligands have drawn wide attention since the discovery of their extensive distribution and unique bidirectional signaling between astrocytes and neurons. The roles of Eph/ephrin bidirectional signaling in the developmental processes have been re- ported in previous research. Recent observations suggest that Eph/ephrin bidirectional signaling continues to be expressed in most regions and cell types in the adult central nervous system, playing diverse roles. The Eph/ephrin complex mediates neurogenesis and angiogenesis, promotes glial scar formation, regulates endocrine levels, inhibits myelin formation and aggravates inflammation and nerve pain caused by injury. ~lhe interaction between Eph and ephrin is also considered to be the key to angiogenesis. This review focus- es on the roles of Eph/ephrin bidirectional signaling in the repair of central nervous system injuries.

关键词： nerve regeneration Eph/ephrin bidirectional signaling central nervous system injury recovery neurons glial cells

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Congenital coronary artery fistulas： dual-source CT findings from consecutive 6624 patients with suspected or confirmed coronary artery disease

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Chinese Medical Journal 2011年第24期124卷 4172-4177页

作者： YUN Hong ZENG Meng-su yang shan jin Hang yang Xue Department of Radiology Zhongshan Hospital Fudan Universityand Shanghai Medical Imaging Institute Shanghai 200032 China

Background Coronary artery fistulas （CAFs） are rare congenital abnormality often unintentionally found in patients with coronary artery disease. Clinical diagnosis of CAFs is difficult due to symptomless or lack of specific symptoms. Dual-source computed tomography （DSCT） might be a useful diagnostic tool for CAFs. The study aimed to retrospectively summarize the imaging features of CAFs delineated at DSCT in 48 CAF patients detected from consecutive 6624 patients with suspected or confirmed coronary artery disease in our institution. Methods Forty-eight patients underwent DSCT angiography by using retrospective electrocardiographic （ECG） gating after infusion of 70 ml of intravenous contrast material during breath hold. Maximum intensity projection （MIP）, curved planar reconstruction （CPR）, and volume rendering technique （VR） were obtained. Anomalous termination of coronary artery in each subject was evaluated by two radiologists （with more than 10 years experience with cardiovascular imaging）, and disagreement between diagnosis readers was settled by a consensus reading. Ten of 48 patients also underwent traditional coronary angiography （CAG） simultaneously. Results In each CAF case, DSCT angiography clearly demonstrated the origin, the termination, the size of abnormal vessel and its course in relation to surrounding great vessels. CAF arising from right coronary artery was the most common type, left circumflex was the least one involved among three coronaries, and pulmonary artery was the most common drainage site. Aneurismal fistulous tract, coronary atherosclerosis, myocardial bridging and anomalous origin of coronary artery were also detected in this group. The demonstration of drainage sites in CAG was consistent with DSCT angiography in 9 patients, and judgment on one anomalous connection in CAG was inconsistent with that in DSCT angiography. Conclusions DSCT angiography could provide accurate delineation of anomalous communications, size and numbers

关键词： coronary vessel anomalies coronary artery disease computed tomography diagnosis

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Construction of recombinant lentivirus SM22alpha-p27-EGFP and its specific effect on smooth muscle cells

Construction of recombinant lentivirus SM22alpha-p27-EGFP an...

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中国神经科学学会第十届全国学术会议

作者： jin-shan yang Wei WANG Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and Technology

Previous reports showed the major pathological manifestation of in-stent restenosis is intimal hyperplasia and vascular remodeling in which excessive proliferation of vascular smooth muscle cells（VSMCs） plays an important *** study was designed to construct SM22alpha-p27-EGFP recombinant lentiviral vector driven by SM22alpha promoter and explore their effects on VSMCs specific p27 protein *** we chose the most appropriate multiplicity of infection（MOI） of recombinant virus for further *** SM22alpha promoter was ***22alpha-p27-EGFP,negative control lentivirus and SM22alpha-null-EGFP were constructed and infected in primary cultured smooth muscle cells and endothelial *** cytometry was used to determine the selectivity of the virus infection and the MOI;Immunofluorescence and Western blot werer applied to detect the p27 gene expression on smooth muscle cells and endomelial ***22alpha promoter was extracted from Rats genome to construct SM22alpha promoter-p27-EGFP and SM22alpha promoter-null-EGFP recombinant lentiviral *** viral titer was 5xl08U/*** showed the SM22alpha promoter could selectively infect smooth muscle cells with an appropriate MOI=*** staining showed SM22alpha promoter could effectively lead to oversxpression of p27 protein in smooth muscle *** Blot proved the existion of recombinant p27 protein in smooth muscle ***:Recombinant lentiviral vector driven by SM22alpha promoter could selectively infect vessel smooth muscle cell and effectively lead to p27 protein overexpression.

关键词： in-stent restenosis SM22alpha promoter p27 recombinant lentivirus

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Cause Analysis and management of massive hemorrhage following Percutaneous nephroscopic pneumatic and ultrasound lithotripsy

Cause Analysis and management of massive hemorrhage followin...

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第十五届全国泌尿外科学术会议

作者： ZHU jin, shan Yu-xi, yang Dong-rong, XUE Bo-xin, SUN Chuan-yang. 苏州大学附属第二医院泌尿外科

Objective: To investigate Cause of massive hemorrhage following Percutaneous nephroscopic pneumatic and ultrasound lithotripsy and it’s management. Methods: A retrospective study was accomplished on 148 patients treaded by Percutaneous nephroscopic pneumatic and ultrasoud lithotripsy from Apr 2005 to May 2008. three patients developed massive hemorrhage requiring blood transfusion more than 600ml,in which one male

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A model of five genes of tumor microenvironment predicts prognosis in Cholangiocarcinoma

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Cancer Advances 2024年第2期7卷 1-12页

作者： jin-shan yang Chuan-Xin Wu Kai Li Ling-Xiang Xu Xing-Lang Wu Qin-Bo Wang Lun-Wei Chen Na Wang Hang Sun Department of Hepatobiliary Surgery The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Department of Hepatobiliary Surgery The Third People’s Hospital of Sichuan ProvinceChengdu 610100China Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqing 400010China

Background:Cholangiocarcinoma(CCA)is highly malignant and has a poor prognosis has a high malignant degree and poor *** purpose of this study is to develop a new prognostic model based on genes related to the tumor microenvironment(TME).Methods:Derived from the discerned differentially expressed genes within The Cancer Genome Atlas(TCGA)dataset,this investigation employed the methodology of weighted gene co-expression network analysis(WGCNA)to ascertain gene co-expressed modules intricately linked to the Tumor Microenvironment(TME)among Cholangiocarcinoma(CCA)*** genes associated with prognosis,as identified through Cox regression analysis,were employed in the formulation of a predictive *** model underwent validation,leading to the development of a risk score formula and ***,we validated the model’s reliability using data from CCA patients in the Gene Expression Omnibus(GEO)database(accession:GSE107943).Results:6139 DEGs were divided into 10 co-expressed gene modules using *** these,two modules(blue module with 832 genes and brown module with 1379 genes)showed high correlation with the *** prognostic genes(BNIP3,COL4A3,SPRED3,CEBPB,PLOD2)were identified through Cox regression analysis,and a prognostic model and risk score formula were developed based on these *** score formula:Risk score=BNIP3×1.70520-COL4A3×2.39815+SPRED3×1.17936+CEBPB×0.40456+PLOD2×***-Meier survival analysis revealed that the survival probabilities of the low-risk group were significantly higher than those of the high-risk ***,the related evaluation indexes suggested that the model exhibited strong predictive ***:The prognostic model,based on five TME-related genes(BNIP3,COL4A3,SPRED3,CEBPB,PLOD2),could accurately assess the prognosis of CCA patients to aid in guiding clinical decisions.

关键词： Cholangiocarcinoma tumor microenvironment prognostic prediction model nomogram

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试论城市用地发展的可持续性──以南京市为例

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现代城市研究 1999年第3期14卷 22-25,32-63页

作者：金涛杨山扬州大学农学院南京师范大学地理科学学院

本文首先论述了南京城市用地的扩张过程，及其伴随城市快速扩张而来的城市物质和社会空间结构的重组，在此背景下提出了土地利用不经济、社会空间分化、城市文化景现变异等问题，最后根据土地与环境问题以及社会问题的矛盾，对城市如何... 详细信息

本文首先论述了南京城市用地的扩张过程，及其伴随城市快速扩张而来的城市物质和社会空间结构的重组，在此背景下提出了土地利用不经济、社会空间分化、城市文化景现变异等问题，最后根据土地与环境问题以及社会问题的矛盾，对城市如何步入可持续的良性发展轨道的问题进行了探讨。

关键词：城市土地利用可持续发展城市社会空间文化景观

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Predictive value of a constructed artificial neural network model for microvascular invasion in hepatocellular carcinoma:A retrospective study

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 88-100页

作者： Hai-yang Nong Yong-Yi Cen shan-jin Lu Rui-Sui Huang Qiong Chen Li-Feng Huang Jian-Ning Huang Xue Wei Man-Rong Liu Lin Li Ke Ding Department of Radiology The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina Department of Radiology Affiliated Hospital of Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Guangxi Clinical Medical Research Center for Hepatobiliary Diseases Affiliated Hospital of Youiiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Ultrasound The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina Department of Hepatobiliary Surgery The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina

BACKGROUND Microvascular invasion(MVI)is a significant risk factor for recurrence and metastasis following hepatocellular carcinoma(HCC)***,there is a paucity of preoperative evaluation approaches for *** To investigate the predictive value of texture features and radiological signs based on multiparametric magnetic resonance imaging in the non-invasive preoperative prediction of MVI in *** Clinical data from 97 HCC patients were retrospectively collected from January 2019 to July 2022 at our *** were classified into two groups:MVI-positive(n=57)and MVI-negative(n=40),based on postoperative pathological *** correlation between relevant radiological signs and MVI status was ***4.6 software and the mutual information method were employed to identify the top 10 dominant texture features,which were combined with radiological signs to construct artificial neural network(ANN)models for MVI *** predictive performance of the ANN models was evaluated using area under the curve,sensitivity,and *** models with relatively high predictive performance were screened using the DeLong test,and the regression model of multilayer feedforward ANN with backpropagation and error backpropagation learning method was used to evaluate the models’*** The absence of a pseudocapsule,an incomplete pseudocapsule,and the presence of tumor blood vessels were identified as independent predictors of HCC *** ANN model constructed using the dominant features of the combined group(pseudocapsule status+tumor blood vessels+arterial phase+venous phase)demonstrated the best predictive performance for MVI status and was found to be automated,highly operable,and very *** The ANN model constructed using the dominant features of the combined group can be recommended as a noninvasive method for preoperative prediction of HCC MVI status.

关键词： Hepatocellular carcinoma Texture analysis Magnetic resonance imaging Microvascular invasion Pseudocapsule Tumor blood vessels

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Numerical Simulation of Fluid Flow Caused by Buoyancy Forces During Vacuum Arc Remelting Process

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Journal of shanghai Jiaotong university(Science) 2011年第3期16卷 272-276页

作者：赵小花李金山杨治军寇宏超胡锐周廉 State Key Laboratory of Solidification Processing Northwestern Polytechnical University

The metallurgical structure and composition of ingots which depend critically on the fluid motion within the molten pool during the vacuum arc remelting(VAR)process have important effect on the subsequent mechanical processes like forging,rolling and *** order to determine the fluid motion of molten pool,a 2D finite element model is established using ANSYS10.0 software,combined with the turbulent fluid flow and heat *** fluid motion caused by thermo buoyancy forces is investigated at different VAR processes in the present *** results indicate that the fluid flows symmetrically along the axis of the molten pool and clockwisely along the circle at the right pool’s *** is also shown that the maximum velocity increases with increasing melting rate and a direct proportional relationship exists.

关键词： vacuum arc remelting(VAR) fluid flow buoyancy force numerical simulation

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彩色电视Y/C数字分离的新算法

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微电子学 1999年第4期29卷 225-230页

作者：黄强郑金山杨莲兴复旦大学专用集成电路与系统国家重点实验室上海200433

电视信号Ｙ／Ｃ数字分离是实现高质量电视视频显示的重要技术。文中分析了传统分离算法存在的问题，提出了一种基于模糊边缘检测的二维Ｙ／Ｃ分离算法，提高了自适应滤波的有效性和稳定性。模拟结果显示，该算法具有较好的Ｙ／... 详细信息

电视信号Ｙ／Ｃ数字分离是实现高质量电视视频显示的重要技术。文中分析了传统分离算法存在的问题，提出了一种基于模糊边缘检测的二维Ｙ／Ｃ分离算法，提高了自适应滤波的有效性和稳定性。模拟结果显示，该算法具有较好的Ｙ／Ｃ分离效果，适合单片ＡＳＩＣ集成，可应用于对图像质量要求较高的数字化电视。

关键词： ASIC 彩色电视机电视信号处理亮色分离

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