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Properties of the QCD matter:review of selected results from the relativistic heavy ion collider beam energy scan(RHIC BES)program

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Nuclear Science and Techniques 2024年第12期35卷 274-311页

作者： jin‑hui chen Xin Dong Xiong‑Hong He Huan‑Zhong Huang Feng Liu Xiao‑Feng Luo Yu‑Gang Ma Li‑Juan Ruan Ming Shao Shu‑Su Shi Xu Sun Ai‑Hong Tang Ze‑Bo Tang Fu‑Qiang Wang Hai Wang Yi Wang Zhi‑Gang Xiao Guan‑Nan Xie Nu Xu Qing‑Hua Xu Zhang‑Bu Xu Chi Yang Shuai Yang Wang‑Mei Zha Ya‑Peng Zhang Yi‑Fei Zhang Jie Zhao Xiang‑Lei Zhu Key Laboratory of Nuclear Physics and Ion‑Beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Nuclear Science Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA QMRC Institute of Modern PhysicsChinese Academy of SciencesLanzhouChina Department of Physics and Astrophysics University of CaliforniaLos AngelesCA 90095USA Key Laboratory of Quark and Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan 430079China Department of Physics Brookhaven National LaboratoryUptonNY 11973USA Department of Modern Physics University of Science and Technology of ChinaHefeiChina Department of Physics Purdue UniversityWest LafayetteIN 47907USA Department of Engineering Physics Tsinghua UniversityBeijingChina Department of Physics Tsinghua UniversityBeijingChina School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Physics and Particle Irradiation(MOE) Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Department of Physics Kent State UniversityKentOH 44242USA Institute of Quantum Matter South China Normal UniversityGuangzhou 510006China

In the paper,we discuss the development of the multigap resistive plate chamber time-of-fight(TOF)technology and the production of the solenoidal tracker at RHIC(STAR)TOF detector in China at the beginning of the twenty-frst ***,recent experimental results from the frst beam energy scan program(BES-I)at the Relativistic Heavy Ion Collider(RHIC)pertaining to measurements of collectivity,chirality,criticality,global polarization,strangeness,heavy favor,dilepton and light nuclei productions are reviewed.

关键词： Heavy ion collision Quark-gluon plasma QCD phase diagram Collectivity Chirality Criticality

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知识产权行政执法体系的合理性构建探讨——以深圳市市场监督管理局为例

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特区经济 2017年第5期 32-35页

作者：李金惠陈忠广东省技术经济研究发展中心广东广州510070 华南理工大学广东广州510070

在知识产权改革的大背景下,我国知识产权行政执法尚存在定位和职能不清等问题。通过行政法和知识产权法两个角度,提炼总结知识产权行政执法体系构建的指导原则,从内部和外部两方面对知识产权行政执法体系进行合理构建,以更好的实现知识... 详细信息

在知识产权改革的大背景下,我国知识产权行政执法尚存在定位和职能不清等问题。通过行政法和知识产权法两个角度,提炼总结知识产权行政执法体系构建的指导原则,从内部和外部两方面对知识产权行政执法体系进行合理构建,以更好的实现知识产权行政执法的目标和功能。

关键词：知识产权行政执法体系指导原则构建

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我国液态奶营销渠道多元整合模式研究——光明乳业渠道多元整合模式实证研究

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上海管理科学 2004年第4期26卷 30-32页

作者：陈洁鲍惠金陈粤上海交通大学管理学院浙江大学管理学院上海太太乐调味品有限公司

本文从研究国内液态奶企业的发展背景入手,分析了现代渠道新格局,即液态奶销售的主流渠道和新兴渠道的交叉混杂形成营销渠道的多元整合模式:分销渠道模式内部多元整合、传统分销渠道模式与订奶模式以及电子商务订奶模式的多元整合模式... 详细信息

本文从研究国内液态奶企业的发展背景入手,分析了现代渠道新格局,即液态奶销售的主流渠道和新兴渠道的交叉混杂形成营销渠道的多元整合模式:分销渠道模式内部多元整合、传统分销渠道模式与订奶模式以及电子商务订奶模式的多元整合模式、产品与渠道组合的多元整合模式。多元整合的渠道拓展模式对液态奶企业从粗放的开拓型向精细的管理型转变有巨大的促进作用,是液态奶企业渠道拓展的创新。

关键词：液态奶企业市场销售市场竞争光明乳业

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Quantitative reconstruction of salinity and precipitation changes in Central Asia over the past 3200 years using diatom and pollen records of lacustrine sediment in Aibi Lake of SW Junggar Basin

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Journal of Earth Science 2025年

作者： Long Pan Guoqiang Li Xiaoyan Wang Ming jin Xinrong He Luo Qin Zhong Wang Wenwei Zhao Chunzhu chen Yuanlu Liu jin Yang Lele Shu Key Laboratory of Western China's Environmental Systems (Ministry of Education)， College of Earth and Environmental Sciences， Lanzhou University College of Earth Sciences， chengdu University of Technology School of Geographic Science， Nantong University Key Laboratory of Land Surface Process and Climate Change in Cold and Arid Regions， Northwest Institute of Eco-Environment and Resources， Chinese Academy of Sciences

The response of lake environments in arid Central Asia to climate change during the Late Holocene over the centennial to millennial timescales remains contentious. The reason that primarily paleoenvironmental proxies interpreting diverse and the scarcity of accurate quantitative reconstruction records. In this study， we employed diatoms and pollen records from lacustrine sediment in the Aibi Lake of SW Junggar Basin to quantitatively reconstruct salinity and watershed precipitation amounts while exploring the associated forcing mechanism. The results indicate that Aibi Lake salinity varied between 2 g/L and 47 g/L during the Late Holocene period， indicating a generally brackish environment， and corresponding to prevailing Tryblionella granulata diatom in the lake basin. Westerly-dominated annual precipitation varied between 250 mm and 320 mm during the Late Holocene period in the basin， exhibiting a generally semi-arid environment and prevailing desert steppe vegetation. The Aibi Lake has a low salinity of average value of ～15 g/L. It exhibits elevated precipitation (average value of ～280 mm) during the periods of the Roman Warm Period (2900-1990 cal yr BP)， Dark Age Cold Period (1570-1140 cal yr BP)， and Little Ice Age (590-120 cal yr BP). The reconstructed precipitation and salinity exhibit a periodicity of ～200 years， which is consistent with the cycle of phase changes of the North Atlantic Oscillation (NAO) and Total Solar Irradiance (TSI). This correlation suggests that variations in NOA and TSI significantly influence the precipitation and salinity changes in Central Asia over centennial to millennial timescales.

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Pronounced impact of size and shape effects on creep rupture life of a K439B superalloy combustion chamber casting simulator

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China Foundry 2025年

作者： Wen-tong Liu Yi-dong Wu Lei Gao jing-yang chen cheng-bo Xiao Xi-dong hui State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Science and Technology on Advanced High Temperature Structural Materials Laboratory Beijing Institute of Aeronautical Materials

The size and shape effect(SSE) of components has become a critical issue for mechanical properties, application reliability, and processing. In this study, the creep rupture life(CRL) of components with different wall thicknesses and positions in a combustion chamber casing simulator made of K439B superalloy was investigated. The intrinsic mechanisms of the SSE were explored from the dendrite structure, volume fraction and size of the γ' phase, and element segregation, etc. It is shown that this casting exhibits a strong SSE of creep rupture life, characterized by a significant difference in the CRL values up to 60% with the variation of wall thickness and position in the casing. In terms of casting technology, the influence of SSE on CRL is actually determined by the cooling rate. The SSE on the creep rupture life originates from the dendrite structure(such as the secondary dendrite arm spacing), volume fraction size of the γ' phase in the dendrite trunk, and elements segregation rate. This work may have implications for the design and application of engineering components with large sizes and complex structures.

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腹部创伤致肝破裂患者术后切口感染的病原学与危险因素分析

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中华医院感染学杂志 2017年第5期27卷 1085-1088页

作者：宋胜江林勇张素惠金凯陈震温州医科大学附属第三医院普外科浙江温州325200 温州医科大学附属第三医院消化内科浙江温州325200

目的探讨腹部创伤合并肝破裂患者术后切口感染的病原学和危险因素分析。方法自2007年1月-2016年1月,回顾性收集医院收治的腹部创伤导致的肝破裂患者325例,根据患者术后是否发生切口感染,将患者分为感染组42例和非感染组283例;分析两组... 详细信息

目的探讨腹部创伤合并肝破裂患者术后切口感染的病原学和危险因素分析。方法自2007年1月-2016年1月,回顾性收集医院收治的腹部创伤导致的肝破裂患者325例,根据患者术后是否发生切口感染,将患者分为感染组42例和非感染组283例;分析两组患者的主要临床特征,探讨腹部创伤致肝破裂患者术后切口的危险因素;同时对切口感染患者的病原学进行分析。结果与非感染组比较,感染组患者年龄显著增加(45.94±13.82vs.42.59±12.82,P=0.015);糖尿病显著增加(28.57%vs.6.01%,P=0.000);多发伤显著增加(19.50%vs.8.13%,P=0.025);出血量显著增加(584.48±258.38vs.476.37±215.73ml,P=0.000);创伤指数显著增加(13.58±5.39vs.9.85±4.62,P=0.000);白细胞显著增加(12.58±3.48vs.8.14±2.87 109/L,P=0.000);C-反应蛋白显著增加(23.48±7.38vs.18.82±6.16mg/L,P=0.000);白蛋白显著降低(28.82±9.12vs.33.85±6.63g/L,P=0.000);单因素和多因素logistic回归分析显示糖尿病、创伤指数增加、白细胞增加、C-反应蛋白增加和白细胞降低是肝破裂患者术后切口感染的危险因素(P<0.05);42例切口感染的患者中,共培养出48株细菌。结论糖尿病、创伤指数增加、白细胞增加、C-反应蛋白增加和白蛋白降低是肝破裂患者术后切口感染的危险因素,最常见的革兰阳性菌和革兰阴性菌分别为金黄色葡萄球菌和大肠埃希菌。

关键词：创伤肝破裂切口感染危险因素分析

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Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

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Traditional Medicine Research 2025年第2期10卷 55-64页

作者： jin-Fang Wu Yi-Sheng chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity

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Surface-confined persistent luminescence with amplified FRET efficiency for cell-cell communication monitoring

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Science China Chemistry 2025年

作者： Ziyun Miao Wenjing Dai Yubin jin Bing Qi Jiayi chen Lingling Qiu Yurong Wei Jie Wang The Key Lab of Health Chemistry&Molecular Diagnosis of Suzhou College of ChemistryChemical Engineering&Materials ScienceSoochow University

Microbial communication monitoring is vital for understanding the mechanisms beneath gut microbiota equilibrium, infections,and biomanufacturing. Herein, we reported monitoring bacterial communication by surface-confined persistent ***, we constructed core-shell structured Zn1.4Ga1.2Ge0.4O4@Zn1.4Ga1.2Ge0.4O4:Cr（ZGGO@ZGGO:Cr） persistent luminescence nanoparticles（PLNPs） with amplified FRET efficiency for the detection of azoreductase（AzoR） that participates in bacterial communication. ZGGO@ZGGO:Cr nanoparticles were functionalized with an azo black hole quencher（ZGGO@ZGGO:Cr-BHQ-3）. Due to the proximity of surface-confined persistent luminescence with the surface-bound BHQ-3,ZGGO@ZGGO:Cr-BHQ-3 exhibited a FRET efficiency up to 1.6 times that of traditional ZGGO:Cr-BHQ-3. Further, the specific catalytic reduction of azo bonds in BHQ-3 by bacterial extracellular AzoR recovers the persistent luminescence of ZGGO@ZGGO:Cr. ZGGO@ZGGO:Cr-BHQ-3 displayed superior sensitivity and speed in detecting extracellular AzoR over ZGGO:Cr-BHQ-3, attributed to its surface-confined persistent luminescence. We found that the peak secretion of AzoR occurs during the exponential growth period of bacteria including S. aureus and E. coli based on the persistent luminescence recovery rate of ZGGO@ZGGO:Cr-BHQ-3. Furthermore, ZGGO@ZGGO:Cr-BHQ-3 was used to probe the communication between different bacterial species. R. palustris is a kind of lycopene-production bacteria. We found that the cohabitation of R. palustris and S. putrefaciens boosted both AzoR secretion and lycopene production. Moreover, the secretion and activity of AzoR positively correlated with lycopene production, suggesting that AzoR may participate in the communication between R. palustris and S. putrefaciens to promote lycopene production. This study offers a robust method to enhance PLNP-based biosensing sensitivity and provides a promising strategy for microbial communication monitoring.

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有限域上一类三项式的研究

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数学的实践与认识 2012年第15期24卷 234-237页

作者：王念平王健康金晨辉解放军信息工程大学电子技术学院河南郑州450004

利用有限域理论,按照扩张次数k的奇偶性,研究了p^k元域上一类三项式的可约性判定问题,并在一定的条件下给出了该类三项式的一个分解式,最后给出了两种利用此类三项式构造新的不可约多项式的方法.

关键词： p^k元域三项式可约性分解式不可约多项式

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Rational design of lipid-activatable NIR-II probes for precisely imaging atherosclerotic plaque

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Science China Chemistry 2025年

作者： Xinyu Xu Yuan Ma hui Cao Li Xu Haoming chen Sulai Liu Wei Sun Guosheng Song Xiaobing Zhang State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan University Department of Hepatobiliary Surgery/Central Laboratory Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University) Department of Cardiology the First Affiliated Hospital of Nanjing Medical University Key Laboratory of Targeted Intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational MedicineNanjing Medical University Shenzhen Research Institute of Hunan University

Atherosclerosis(AS) is a prevalent condition associated with cardiovascular and cerebrovascular diseases, featuring lipid-laden plaque; however, the insufficient resolution and low sensitivity of traditional medical imaging techniques limit their application in lipid imaging. Currently, the second near-infrared(NIR-II) fluorescence imaging offers promising sensitivity and convenience. However, existing probes have limitations in terms of signal-to-background ratio, penetration depth, and tissue scattering. Herein, we use a molecular regulatory strategy to design a lipid-activatable probe Rh-965 with high specificity and NIR-II emission for improved imaging potential in deep tissues. The potential of Rh-965 for imaging plaque lipids in mice with AS is demonstrated by localizing carotid artery plaques using NIR-II imaging. The development of more stable lipid-activated NIR-II probes can significantly enhance atherosclerosis diagnosis and facilitate in vivo imaging in deeper tissues.

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