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A novel fracture-cavity reservoir outcrop geological knowledge base construction method considering parameter collection and processing,mutual transformation of data-knowledge,application and update

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Petroleum Science 2024年第4期21卷 2184-2202页

作者： Qi-Qiang ren jin-Liang Gao Peng Zhu Meng-Ping Li Jian-Wei feng Qiang jin San Zhang Institute of Sedimentary Geology Chengdu University of TechnologyChengdu610059SichuanChina PetroChina Research Institute of Petroleum Exploration and Development Beijing100083China School of Energy Chengdu University of TechnologyChengdu610059SichuanChina School of Resources and Geosciences China University of Mining and TechnologyXuzhou221018JiangsuChina School of Geosciences China University of Petroleum(East China)Qingdao266580ShandongChina School of Geosciences Yangtze UniversityWuhan430100HubeiChina

This study endeavors to formulate a comprehensive methodology for establishing a Geological Knowledge Base(GKB)tailored to fracture-cavity reservoir outcrops within the North Tarim *** acquisition of quantitative geological parameters was accomplished through diverse means such as outcrop observations,thin section studies,unmanned aerial vehicle scanning,and high-resolution ***,a three-dimensional digital outcrop model was generated,and the parameters were *** assessment of traditional geological knowledge was conducted to delineate the knowledge framework,content,and system of the *** basic parameter knowledge was extracted using multiscale fine characterization techniques,including core statistics,field observations,and microscopic thin section *** mechanism knowledge was identified by integrating trace elements from filling,isotope geochemical tests,and water-rock simulation *** representational knowledge was then extracted by employing various methods such as multiple linear regression,neural network technology,and discriminant ***,an analogy study was performed on the karst fracture-cavity system(KFCS)in both outcrop and underground reservoir *** results underscored several key findings:(1)Utilization of a diverse range of techniques,including outcrop observations,core statistics,unmanned aerial vehicle scanning,high-resolution cameras,thin section analysis,and electron scanning imaging,enabled the acquisition and standardization of *** facilitated effective management and integration of geological parameter data from multiple sources and scales.(2)The GKB for fracture-cavity reservoir outcrops,encompassing basic parameter knowledge,key mechanism knowledge,and significant representational knowledge,provides robust data support and systematic geological insights for the intricate and in-depth examination of the genetic mechanisms of fracture-cavity reservoi

关键词： Geological knowledge base Karst fracture-cavity system Mutual transformation of data-knowledge Knowledge base content and application Tarim basin

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Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui Meng Meina Quan Ling Wang jing ren Chenguang Zheng Jiajia Yang Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Innovation Center for Neurological Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive *** presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s *** use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent *** a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive *** article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound *** is placed on the benefits of introducing these treatment methods and their potential *** found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque *** believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods.

关键词： Alzheimer’s disease blood-brain barrier drugs magnetic resonance imaging-guided focused ultrasound microbubbles scanning ultrasound ultrasound ultrasound stimulation

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Induced pluripotent stem cell-related approaches to generate dopaminergic neurons for Parkinson's disease

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Neural Regeneration Research 2025年第11期20卷 3193-3206页

作者： Ling-Xiao Yi Hui ren Woon Genevieve Saw Li Zeng Eng King Tan Zhi Dong Zhou National Neuroscience Institute Singapore Nanyang Technology University Singapore Department of Neurology Singapore General HospitalSingapore Signature Research Program in Neuroscience and Behavioral Disorders Duke-NUS Medical SchoolSingapore

The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative *** the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and *** induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease *** current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem *** benefits of induced pluripotent stem cell-based research are *** dopaminergic neuron differentiation protocols from induced pluripotent stem cells are *** emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are ***,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.

关键词： dopaminergic neurons induced pluripotent stem cells Parkinson's disease stem cell approaches

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Transforming growth factor-beta 1 enhances discharge activity of cortical neurons

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Neural Regeneration Research 2025年第2期20卷 548-556页

作者： Zhihui ren Tian Li Xueer Liu Zelin Zhang Xiaoxuan Chen Weiqiang Chen Kangsheng Li Jiangtao Sheng Department of Microbiology and Immunology Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular ImmunopathologyShantou University Medical CollegeShantouGuangdong ProvinceChina Department of Neurosurgery First Affiliated Hospital of Shantou University Medical CollegeShantouGuangdong ProvinceChina

Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system *** neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types ***-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related ***,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain *** this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from *** found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 *** VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and Jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical *** findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological ***,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.

关键词： central nervous system cortical neurons ERK firing properties JNK Nav1.3 p38 transforming growth factor-beta 1 traumatic brain injury voltage-gated sodium currents

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Bearing Fault Diagnosis Based on the Markov Transition Field and SE-IShufflenetV2 Model

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Structural Durability & Health Monitoring 2025年第1期19卷 125-144页

作者： Chaozhi Cai Tiexin Xu Jianhua ren Yingfang Xue School of Mechanical and Equipment Engineering Hebei University of EngineeringHandan056038China

A bearing fault diagnosis method based on the Markov transitionﬁeld(MTF)and SEnet(SE)-IShufﬂenetV2 model is proposed in this paper due to the problems of complex working conditions,low fault diagnosis accuracy,and poor generalization of rolling ***,MTF is used to encode one-dimensional time series vibration sig-nals and convert them into time-dependent and unique two-dimensional feature ***,the generated two-dimensional dataset is fed into the SE-IShufﬂenetV2 model for training to achieve fault feature extraction and classiﬁ*** paper selects the bearing fault datasets from Case Western Reserve University and Paderborn University to experimentally verify the effectiveness and superiority of the proposed *** generalization performance of the proposed method is tested under the variable load condition and different signal-to-noise ratios(SNRs).The experimental results show that the average accuracy of the proposed method under different working conditions is 99.2%without adding *** accuracy under different working conditions from 0 to 1 HP is 100%.When the SNR is 0 dB,the average accuracy of the proposed method can still reach 98.7%under varying working ***,the bearing fault diagnosis method proposed in this paper is characterized by high accuracy,strong anti-noise ability,and ***,the proposed method can also overcome the inﬂuence of variable working conditions on diagnosis accuracy,providing method support for the accurate diagnosis of bearing faults under strong noise and variable working conditions.

关键词： Bearings Markov transitionﬁeld SE-IShufﬂenetV2

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图书珍藏馆坡屋面工程设计与分析

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建筑技术 2024年第22期55卷 2813-2816页

作者：周浩杨瑛高鑫冯金仁邵喜诚宋必达中国建筑第五工程局有限公司长沙410000

针对大角度坡屋面采用钢筋桁架楼承板的情况,提出了局部采用异形H形钢主梁的解决方案,并给出了具体的结构布置。利用ANSYS、ABAQUS分别对异形H形钢梁和普通H形钢梁进行了施工阶段、使用阶段的受力分析。结果表明,在相同条件下两者的应... 详细信息

针对大角度坡屋面采用钢筋桁架楼承板的情况,提出了局部采用异形H形钢主梁的解决方案,并给出了具体的结构布置。利用ANSYS、ABAQUS分别对异形H形钢梁和普通H形钢梁进行了施工阶段、使用阶段的受力分析。结果表明,在相同条件下两者的应力和变形差异较小;对异形H形钢梁进行了极限承载力计算,验证了异形H形钢梁的良好受力性能。结合项目情况,分别给出了箱形柱、普通H形钢次梁与异形H形钢主梁连接节点的构造方式,并进行了梁柱节点的受力分析,验证了节点的可靠性。结合建筑效果,给出了木构筑的节点构造形式,可为同类工程施工提供参考。

关键词：坡屋面异形H形钢梁极限承载力节点分析

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A review on direct synthesis of dimethoxymethane

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Chinese Journal of Chemical Engineering 2022年第10期50卷 43-55页

作者： Jia ren feng Xin Yongsheng Xu School of Chemical Engineering and Technology Tianjin UniversityTianjin 300050China

Polyoxymethylene dimethyl ethers are recognized as the prospective diesel additive to decrease the pollutant emission from the light-duty vehicles,which can be polymerize form the monomer of dimethoxymethane(DMM).The industrial synthesis of DMM is mainly involved two-step process:methanol is oxidized to form the formaldehyde in fixed bed reactor and then reacted with the generated formaldehyde through acetalization in continuous stirred-tank *** to huge energy consumption,this typical synthesis route of DMM needs to be upgraded and more green routes should be *** this review,four state-of-the-art one-step direct synthetic routes,including two upgrading routes(methanol direct oxidation and direct dehydrogenation)and two green routes(methanol diethyl ether direct oxidation and carbon oxides direct hydrogenation),have been summarized and *** with the reaction mechanism and catalytic performance on the different catalysts,the challenges and opportu nities for every synthetic route are *** relationships between catalyst structu re and property in different synthesis strategy are also investigated and then the suggestions of the design of catalyst are given about future research directions that efforts should be made ***,this review can bridge the gap between newly developed catalysts and synthesis technology to realize their commercial applications in the near future.

关键词： Dimethoxymethane(DMM) Direct synthesis Reaction mechanism Catalyst

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Suppressing interfacial side reactions of zinc metal anode via isolation effect toward high-performance aqueous zinc-ion batteries

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Nano Research 2023年第5期16卷 6789-6797页

作者： feng Tao Kaijia feng Yong Liu Jiangzhuo ren Yi Xiong Chengbo Li fengzhang ren School of Materials Science and Engineering Provincial and Ministerial Co-construction of Collaborative Innovation Center for Non-ferrous Metal New Materials and Advanced Processing TechnologyHenan University of Science and TechnologyLuoyang 471023China School of Construction Machinery Chang’an UniversityXi’an 710064China School of Materials Science and Engineering Anyang Institute of TechnologyAnyang 455000China

Aqueous zinc(Zn)-ion batteries(AZIBs)are one of the most promising large-scale energy storage devices because of the excellent features of zinc metal anodes,including high theoretical capacity(5,855 mAh·cm^(–3)and 820 mAh·g^(−1)),high safety,and natural ***,the large-scale applications of AZIBs are mainly limited by the severe interfacial side reactions of zinc metal anodes,which results in low plating/stripping Coulombic efficiency and poor cycling *** address this issue,we report an artificial Ta_(2)O_(5)protective layer on zinc foil(Ta_(2)O_(5)@Zn)for suppressing side reactions during Zn deposition/*** results of density functional theory calculation and experiments indicate that Ta_(2)O_(5)@Zn anode can inhibit the side reactions between the electrolyte and zinc anode through the isolation *** from this advantage,the symmetric cells with Ta_(2)O_(5)@Zn anode delivered an ultralong lifespan of 3,000 h with a low overpotential at 0.25 mA·cm^(−2)for 0.05 mAh·cm^(−2).Furthermore,the full cells consisting of Ta_(2)O_(5)@Zn anode and MnO_(2)or NH_(4)V_(4)O_(10)cathode all present outstanding electrochemical performance,indicating its high reliability in practical *** strategy brings new opportunities for the future development of rechargeable AZIBs.

关键词： zinc metal anode Ta_(2)O_(5)coating isolation effect interfacial side reactions electrochemical performance

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Modeling of liquid film thickness around Taylor bubbles rising in vertical stagnant and co-current slug flowing liquids

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Chinese Journal of Chemical Engineering 2023年第6期58卷 179-194页

作者： Weikai ren Runsong Dai Ningde jin School of Electrical and Information Engineering Tianjin UniversityTianjin 300072China

The hydrodynamic study of the liquid film around Taylor bubbles in slug flow has great significance for understanding parallel flow and interaction between Taylor *** prediction models for liquid film thickness mainly focus on stagnant flow,and some of them remain inaccurate ***,in the industrial process,the slug flow essentially is co-current ***,in this paper,the liquid film thickness is studied by theoretical analysis and experimental methods under two conditions of stagnant and co-current ***,under the condition of stagnant flow,the present work is based on Batchelor's theory,and modifies Batchelor's liquid film thickness model,which effectively improves its prediction *** the condition of co-current flow,the prediction model of average liquid film thickness in slug flow is established by force and motion *** bubble length is introduced into the model as an important *** experiments were carried out in the pipe with an inner diameter of 20 *** liquid film thickness,Taylor bubble velocity and length were measured by distributed ultrasonic sensor and intrusive cross-correlation conductivity *** the predicted value of the model with the measured results,the relative error is controlled within 10%.

关键词： Slug flow Taylor bubble Liquid film thickness Ultrasonic sensor Physical model

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Thermal behavior analysis of a pouch type Li[Ni0.7Co0.15Mn0.15]O2-based lithium-ion battery

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Rare Metals 2016年第4期35卷 309-319页

作者： feng-Ling Yun Ling Tang Wen-Cheng Li Wei-ren jin jing Pang Shi-Gang Lu General Research Institute for Nonferrous Metalsl R&D Center for Vehicle Battery and Energy StorageBeijing 100088China

Since lithium-ion battery with high energy density is the key component for next-generation electrical vehicles, a full understanding of its thermal behaviors at different discharge rates is quite important for the design and thermal management of lithium-ion batteries （LIBs） pack/module. In this work, a 25 Ah pouch type Li[Ni0.7 Co0.15Mn0.15]O2/graphite LIBs with specific energy of 200 ***-1 were designed to investigate their thermal behaviors, including temperature distribution, heat generation rate, heat capacity and heat transfer coefficient with environment. Results show that the temperature increment of the charged pouch batteries strongly depends on the discharge rate and depth of discharge. The heat generation rate is mainly influenced by the irreversible heat effect, while the reversible heat is important at all discharge rates and contributes much to the middle evolution of the tem- perature during discharge, especially at low rate. Subse- quently, a prediction model with lumped parameters was used to estimate the temperature evolution at different discharge rates of LIBs. The predicted results match well with the experimental results at all discharge rates. Therefore, the thermal model is suitable to predict the average temperature for the large-scale batteries under normal operating conditions.

关键词： Lithium-ionLi[Ni0.7Co0.15Mn0.15]O2 battery Thermal behavior High specific energy

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