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Migration and accumulation characteristics of natural gas hydrates in the uplifts and their slope zones in the Qiongdongnan Basin,China

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China Geology 2022年第2期5卷 234-250页

作者： Yu-lin He jin-qiang Liang Zeng-gui Kuang Wei Deng jin-feng ren Hong-fei Lai Miao-miao Meng Wei Zhang Southern Marine Science and Engineering Guangdong Laboratory Guangzhou 511458China Guangzhou Marine Geological Survey China Geological SurveyMinistry of Natural ResourcesGuangzhou 510075China National Engineering Research Center of Gas Hydrate Exploration and Development Guangzhou 511458China

Various factors controlling the accumulation of natural gas hydrates(NGHs)form various enrichment and accumulation modes through organic *** study mainly analyzes the geological and geophysical characteristics of the NGHs occurrence in the uplifts and their slope zones within the deep-water area in the Qiongdongnan(QDN)Basin(also referred to as the study area).Furthermore,it investigates the dominant governing factors and models of NGHs migration and accumulation in the study *** results are as follows.(1)The uplifts and their slope zones in the study area lie in the dominant pressure-relief direction of fluids in central hydrocarbon-rich sags in the area,which provide sufficient gas sources for the NGHs accumulation and enrichment through pathways such as gas chimneys and faults.(2)The top and flanks of gas chimneys below the bottom simulating reflectors(BSRs)show high-amplitude seismic reflections and pronounced transverse charging of free gas,indicating the occurrence of a large amount of gas accumulation at the heights of the uplifts.(3)Chimneys,faults,and high-porosity and high-permeability strata,which connect the gas hydrate temperature-pressure stability zones(GHSZs)with thermogenic gas and biogenic gas,form the main hydrate migration system.(4)The reservoir system in the study area comprises sedimentary interlayers consisting of mass transport deposits(MTDs)and *** addition,the reservoir system has developed fissure-and pore-filling types of hydrates in the *** above well-matched controlling factors of hydrate accumulation enable the uplifts and their slope zones in the study area to become the favorable targets of NGHs exploration.

关键词： Gas chimney Overpressure Migration characteristics of gas hydrates Accumulation characteristics of gas hydrates Oil and gas exploration engineering NGHs exploration trial engineering Uplifts and slope zones Qiongdongnan Basin China

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Deep-large faults controlling on the distribution of the venting gas hydrate system in the middle of the Qiongdongnan Basin, South China Sea

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China Geology 2024年第1期7卷 36-50页

作者： jin-feng ren Hai-jun Qiu Zeng-gui Kuang Ting-wei Li Yu-lin He Meng-jie Xu Xiao-xue Wang Hong-fei Lai jin Liang National Engineering Research Center of Gas Hydrate Exploration and Development Guangzhou 511458China Guangzhou Marine Geological Survey China Geological SurveyGuangzhou 511458China China Geological Survey Ministtry of Natural ResourcesBeijing 100037China

Many locations with concentrated hydrates at vents have confirmed the presence of abundant thermogenic gas in the middle of the Qiongdongnan Basin(QDNB).However,the impact of deep structures on gasbearing fluids migration and gas hydrates distribution in tectonically inactive regions is still *** this study,the authors apply high-resolution 3D seismic and logging while drilling(LWD)data from the middle of the QDNB to investigate the influence of deep-large faults on gas chimneys and preferred gasescape *** findings reveal the following:(1)Two significant deep-large faults,F1 and F2,developed on the edge of the Songnan Low Uplift,control the dominant migration of thermogenic hydrocarbons and determine the initial locations of gas chimneys.(2)The formation of gas chimneys is likely related to fault activation and *** chimney 1 is primarily arises from convergent fluid migration resulting from the intersection of the two faults,while the gas chimney 2 benefits from a steeper fault plane and shorter migration distance of fault F2.(3)Most gas-escape pipes are situated near the apex of the two *** reactivations facilitate free gas flow into the GHSZ and contribute to the formation of fracture‐filling hydrates.

关键词： Venting gas hydrates Deep-large faults Gas chimney Gas-escape pipes High-resolution 3D seismic Logging while drilling Qiongdongnan Basin South China Sea

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Risk factors for mortality after coronary artery bypass grafting in patients with low left ventricular ejection fraction

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Chinese Medical Journal 2007年第4期120卷 317-322页

作者： WANG jin XIAO feng ren Jian LI Yan ZHANG Ming-li Department of Cardiac Surgery Peking University First Hospital Beijing 100034 China

Background We managed to assess and confirm the risk factors for mortality after coronary artery bypass grafting （CABG） operations so as to map out the proper guidance of surgical strategy especially in patients with low left ventncular ejection fraction （LVEF） in domestic polyclinic like ours. Methods Five hundred and forty-eight consecutive patients underwent CABG from December 1999 through August 2005 were analyzed retrospectively. Eighty-nine cases had an LVEF of 40% or less. All together twenty-two candidate factors were evaluated for their association with perioperative death using univariate and multivariate stepwise Logistic analysis. Results When data from all the patients who had undergone CABG were taken into account, LVEF, left ventricular end diastolic diameter （LVEDD）, mitral regurgitation, aneurysm of the heart wall, mitral repair/replacement, resection of aneurysm, concomitant aortic valve replacement, and perioperative intra-aortic balloon counter-pulsation （IABP）, left ventricular assist device （LVAD） and cardiopulmonary bypass （CPB） all showed an association with perioperative death in univariate analysis, while an LVEF of 〉40%, on the other hand, appeared to be a protective factor. In multivariate analysis, moderate to severe mitral regurgitation, aneurysm of the heart wall, repair of septal perforation and aortic regurgitation were proved to be risk factors. When the analysis was restricted to patients with an LVEF of 40% or less, such variables as age, LVEDD, mitral regurgitation, mitral repair/replacement, IABP, and CPB were qualified as risk factors in a univariate analysis. Age, moderate mitral regurgitation, aneurysm of the heart wall, CPB, left main coronary artery disease and female were associated with pefioperative death in a multivariate logistic regression analysis. Conclusions Concerning the prognosis, patients who undergo CABG would have different risk factors when data from all the enrolled patients or data from patients with

关键词： ventricular dysfunction, left coronary artery bypass risk factors

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Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： Jie jin Huajing Zhang Qianying Lu Linqiang Tian Sanqiao Yao feng Lai Yangfan Liang Chuanchuan Liu Yujia Lu Sijia Tian Yanmei Zhao Wenjie ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina Clinical Medical Center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health Central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina School of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review focuses on the use of nanocarrier systems for the efficient and precise delive ry of siRNAs,discussing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can precisely"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic strategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

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可分解时域信号的采样分析

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通信学报 2002年第8期23卷 45-51页

作者：冯锦任长学湖南大学电气信息工程学院湖南长沙410082

模拟信号的数字化一直是信号处理中的基本问题,在这些信号中有一类信号可以分解为一些已知信号的线性和。本文从纯时域角度出发,以线性代数作为工具给出了这类信号的分析理论及相应的推论,同时利用这些结论对典型的带限信号进行了分析... 详细信息

模拟信号的数字化一直是信号处理中的基本问题,在这些信号中有一类信号可以分解为一些已知信号的线性和。本文从纯时域角度出发,以线性代数作为工具给出了这类信号的分析理论及相应的推论,同时利用这些结论对典型的带限信号进行了分析并初步探讨了这类信号的采样与恢复的实现问题。

关键词：可分解时域信号采样线性基波信号分析

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Iron-handling solute carrier SLC22A17 as a blood-brain barrier target after stroke

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Neural Regeneration Research 2025年第11期20卷 3207-3208页

作者： Xueqi ren Wenlu Li Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Neuroprotection Research Laboratories Departments of Radiology and NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can induce ferroptosis,a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload(Li and Jia,2023).

关键词： death specialized barrier

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Optimizing the key parameter to accelerate the recovery of AMOC under a rapid increase of greenhouse gas forcing

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 39-45页

作者： Haolan ren Fei Zheng Tingwei Cao Qiang Wang International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina College of Oceanography Hohai UniversityNanjingChina CAS Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning Circulation(AMOC)plays a central role in long-term climate variations through its heat and freshwater transports,which can collapse under a rapid increase of greenhouse gas forcing in climate *** studies have suggested that the deviation of model parameters is one of the major factors in inducing inaccurate AMOC *** this work,with a low-resolution earth system model,the authors try to explore whether a reasonable adjustment of the key model parameter can help to re-establish the AMOC after its *** a new optimization strategy,the extra freshwater flux(FWF)parameter is determined to be the dominant one affecting the AMOC’s *** traditional ensemble optimal interpolation(EnOI)data assimilation and new machine learning methods are adopted to optimize the FWF parameter in an abrupt 4×CO_(2) forcing experiment to improve the adaptability of model parameters and accelerate the recovery of *** results show that,under an abrupt 4×CO_(2) forcing in millennial simulations,the AMOC will first collapse and then re-establish by the default FWF parameter ***,during the parameter adjustment process,the saltier and colder sea water over the North Atlantic region are the dominant factors in usefully improving the adaptability of the FWF parameter and accelerating the recovery of AMOC,according to their physical relationship with FWF on the interdecadal timescale.

关键词： Recovery of AMOC 4×CO_(2)forcing Key parameter Parameter estimation Data assimilation Machine learning

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一种汽化过氧化氢消毒装置对物体表面和空气消毒效果研究

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中国消毒学杂志 2016年第12期33卷 1141-1145页

作者：苏裕心张文福帖金凤任哲韩杰魏秋华解放军疾病预防控制所北京100071

目的观察一种汽化过氧化氢消毒装置对室内空气和物体表面的消毒效果。方法采用载体定量杀菌实验方法,对某汽化过氧化氢消毒装置杀灭物体表面和室内空气中细菌的效果进行观察。结果该汽化过氧化氢消毒装置使用专门配套的含量为80 g/L过... 详细信息

目的观察一种汽化过氧化氢消毒装置对室内空气和物体表面的消毒效果。方法采用载体定量杀菌实验方法,对某汽化过氧化氢消毒装置杀灭物体表面和室内空气中细菌的效果进行观察。结果该汽化过氧化氢消毒装置使用专门配套的含量为80 g/L过氧化氢水溶液作为消毒剂。在28 m^3密闭实验舱内,以4 ml/m^3用量(折合过氧化氢浓度为320 mg/m^3),启动该过氧化氢消毒装置于室温下消毒作用60 min,对布片上枯草杆菌黑色变种芽孢的杀灭率可以达到99.9%以上。在130 m^3办公室内,消毒液用量为10 ml/m^3(折合过氧化氢浓度为800 mg/m^3),启动该消毒装置作用30 min,对载体上枯草杆菌黑色变种芽孢的杀灭率可达99.9%。在20 m^3密闭空气实验舱内,以0.5 ml/m^3用量,启动该过氧化氢消毒装置液消毒作用20 min,对舱内空气中白色葡萄球菌的杀灭率为99.9%;在90 m^3房间内,以1.0 ml/m^3用量,启动该过氧化氢消毒装置消毒作用60 min,对空气中自然菌的消亡率>90.0%。结论该汽化过氧化氢消毒装置使用较低浓度过氧化氢消毒液,汽化后对物体表面上细菌芽孢和空气中细菌繁殖体均具有较好的杀灭效果。

关键词：汽化过氧化氢消毒装置消毒液细菌芽孢物体表面室内空气消毒效果

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乒乓球运动者正手弧圈球不同触地模式的下肢生物力学变化

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中国组织工程研究 2025年第14期29卷 2995-3001页

作者：晋鹏飞任杰上海体育大学中国乒乓球学院上海市200438

背景:探讨基于步法的足部触地模式对乒乓球运动中下肢关节运动特征的影响,可为指导下肢训练提供科学依据。目的:对比乒乓球运动中不同触地模式下的运动学和动力学差异。方法:使用动作捕捉和三维测力台同步采集17名专业乒乓球运动员在正... 详细信息

背景:探讨基于步法的足部触地模式对乒乓球运动中下肢关节运动特征的影响,可为指导下肢训练提供科学依据。目的:对比乒乓球运动中不同触地模式下的运动学和动力学差异。方法:使用动作捕捉和三维测力台同步采集17名专业乒乓球运动员在正常触地和全脚掌触地模式下优势侧下肢的运动学和动力学数据。配对样本t检验用于分析关节角度、地面反作用力、关节反作用力和关节力矩等离散指标的统计学差异;统计参数映射用于分析足底压力中心移动轨迹和膝关节力矩等时间序列数据的统计学差异。结果与结论:①正常触地模式下的膝关节内翻、侧向地面反作用力、膝关节垂直反作用力和伸膝力矩峰值显著高于全脚掌触地模式;②在足底压力中心移动距离中的89%-91%运动阶段,正常触地模式压力中心显著远于全脚掌触地模式;③在X轴力矩曲线中的23%-38%运动阶段,正常触地模式的伸膝力矩显著大于全脚掌触地模式;④在Y轴力矩曲线的8%-18%运动阶段,全脚掌触地模式显著大于正常触地模式。通过对比不同触地模式的下肢生物力学特征值和统计参数映射分析结果,认为全脚掌触地模式可能是影响乒乓球运动表现的重要因素。乒乓球运动中需要针对性地对触地模式进行调整和练习,避免使用全脚掌触地模式,提升乒乓球运动者下肢运动能力。

关键词：触地模式乒乓球运动学动力学运动表现

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Phase Transformation and Carbide Precipitation of Functional Gradient Semi-solid 9Cr18 Steel

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Acta Metallurgica Sinica(English Letters) 2018年第8期31卷 823-830页

作者： Yong-jin Wang ren-Bo Song ren-feng Song School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Institute of Industrial Science The University of TokyoKomaba 4-6-1MeguroTokyo 153-8505Japan Ansteel Mining Engineering Corporation Anshan 114004China

The unique phase transformation and carbide evolution in 9Cr18 steel were investigated during semi-solid forming and subsequent heat treatment. The functional gradient thixoforging 9Cr18 component was divided into inner area and edge area. Microstructure evolution was different at each area. After semi-solid cooling, the solid particles in the inner area were retained as meta-austenite. During annealing, M_（23）C_6 carbide began to precipitate when temperature reached 700 °*** transformation occurred when temperature reached 800 °C. The occurrence of M_（23）C_6 carbide and martensite structure would be harmful to the mechanical properties of inner area. In the edge area, the liquid underwent eutectic transformation to form bar-shape M_7C_3 carbide and secondary austenite after semi-solid cooling. The width of bar-shape carbide would decrease during annealing. By controlling the carbide evolution, we could tailor the functional gradient material with required property.

关键词： Semi-solid forming Solid/liquid phase Annealing Carbide precipitation

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