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Physiological and pathological functions of circular RNAs in the nervous system

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Neural Regeneration Research 2024年第2期19卷 342-349页

作者： Min zhou Shi Li chuan Huang School of Life Sciences Chongqing UniversityChongqingChina

Circular RNAs(circRNAs)are a class of covalently closed single-stranded RNAs that are expressed during the development of specific cells and *** play crucial roles in physiological and pathological processes by sponging microRNAs,modulating gene transcription,controlling the activity of certain RNA-binding proteins,and producing functional peptides.A key focus of research at present is the functionality of circRNAs in the nervous system and several advances have emerged over the last 2 ***,the precise role of circRNAs in the nervous system has yet to be comprehensively *** this review,we first summarize the recently described roles of circRNAs in brain development,maturity,and ***,we focus on the involvement of circRNAs in various diseases of the central nervous system,such as brain cancer,chronic neurodegenerative diseases,acute injuries of the nervous system,and neuropathic pain.A better understanding of the functionality of circRNAs will help us to develop potential diagnostic,prognostic,and therapeutic strategies to treat diseases of the nervous system.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis brain development circRNAs neuropathic pain Parkinson’s disease

C-CORE:Clustering by Code Representation to Prioritize Test Cases in Compiler Testing

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 2069-2093页

作者： Wei zhou Xincong Jiang chuan Qin School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai200240China Hikvision Research Institute Hangzhou Hikvision Digital Technology Co.Ltd.Hangzhou310051China

Edge devices,due to their limited computational and storage resources,often require the use of compilers for program ***,ensuring the security and reliability of these compilers is of paramount importance in the emerging field of edge *** widely used testing method for this purpose is fuzz testing,which detects bugs by inputting random test cases into the target ***,this process consumes significant time and *** improve the efficiency of compiler fuzz testing,it is common practice to utilize test case prioritization *** researchers use machine learning to predict the code coverage of test cases,aiming to maximize the test capability for the target compiler by increasing the overall predicted coverage of the test ***,these methods can only forecast the code coverage of the compiler at a specific optimization level,potentially missing many optimization-related *** this paper,we introduce C-CORE(short for Clustering by Code Representation),the first framework to prioritize test cases according to their code representations,which are derived directly from the source *** approach avoids being limited to specific compiler states and extends to a broader range of compiler ***,we first train a scaled pre-trained programming language model to capture as many common features as possible from the test cases generated by a *** this pre-trained model,we then train two downstream models:one for predicting the likelihood of triggering a bug and another for identifying code representations associated with ***,we cluster the test cases according to their code representations and select the highest-scoring test case from each cluster as the high-quality test *** reduction in redundant testing cases leads to time *** evaluation results reveal that code representations are better at distinguishing test capabilities,and C-CORE significantly enhanc

关键词： Compiler testing test case prioritization code representation

Design of AI-Enhanced and Hardware-Supported Multimodal E-Skin for Environmental Object Recognition and Wireless Toxic Gas Alarm

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Nano-Micro Letters 2024年第12期16卷 1-22页

作者： Jianye Li Hao Wang Yibing Luo Zijing zhou He Zhang Huizhi Chen Kai Tao chuan Liu Lingxing Zeng Fengwei Huo jin Wu State Key Laboratory of Optoelectronic Materials and Technologies and the Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information TechnologySun Yat-Sen UniversityGuangzhou 510275People’s Republic of China Ministry of Education Key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China Research&Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518063People’s Republic of China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005People’s Republic of China Key Laboratory of Flexible Electronics(KLOFE) School of Flexible Electronics(Future Technologies)Nanjing Tech University30 South Puzhu RoadNanjing 211816People’s Republic of China State Key Laboratory of Transducer Technology Shanghai 200050People’s Republic of China Guangdong Provincial Key Laboratory of Technique and Equipment for Macromolecular Advanced Manufacturing Guangzhou 510641People’s Republic of China State Key Laboratory of Polymer Materials Engineering Sichuan UniversityChengdu 610065People’s Republic of China Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs and School of Pharmacy Guangdong Medical UniversityDongguan 523808People’s Republic of China The First Dongguan Affiliated Hospital Guangdong Medical UniversityDongguan 523808People’s Republic of China Engineering Research Center of Polymer Green Recycling of Ministry of Education College of Environment and ResourcesFujian Normal UniversityFuzhou 350007People’s Republic of China

Post-earthquake rescue missions are full of challenges due to the unstable structure of ruins and successive *** of the current rescue robots lack the ability to interact with environments,leading to low rescue *** multimodal electronic skin(e-skin)proposed not only reproduces the pressure,temperature,and humidity sensing capabilities of natural skin but also develops sensing functions beyond it—perceiving object proximity and NO2 *** multilayer stacked structure based on Ecoflex and organohydrogel endows the e-skin with mechanical properties similar to natural *** robots integrated with multimodal e-skin and artificial intelligence(AI)algorithms show strong environmental perception capabilities and can accurately distinguish objects and identify human limbs through grasping,laying the foundation for automated post-earthquake ***,the combination of e-skin and NO2 wireless alarm circuits allows robots to sense toxic gases in the environment in real time,thereby adopting appropriate measures to protect trapped people from the toxic *** e-skin powered by AI algorithms and hardware circuits exhibits powerful environmental perception and information processing capabilities,which,as an interface for interaction with the physical world,dramatically expands intelligent robots’application scenarios.

关键词： Stretchable hydrogel sensors Multimodal e-skin Artificial intelligence Post-earthquake rescue Wireless toxic gas alarm

An Improved Bounded Conflict-Based Search for Multi-AGV Pathfinding in Automated Container Terminals

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2705-2727页

作者： Xinci zhou jin Zhu Shanghai Maritime University Logistics Science and Engineering Research InstituteShanghai200000China

As the number of automated guided vehicles(AGVs)within automated container terminals(ACT)continues to rise,conflicts have becomemore *** point and edge conflicts ofAGVs,amulti-AGVconflict-free path planning model has been formulated to minimize the total path length of AGVs between shore bridges and *** larger terminalmaps and complex environments,the grid method is employed to model AGVs’road *** improved bounded conflict-based search(IBCBS)algorithmtailored to ACT is proposed,leveraging the binary tree principle to resolve conflicts and employing focal search to expand the search *** experiments involving 60 AGVs indicate a reduction in computing time by 37.397%to 64.06%while maintaining the over cost within 1.019%.Numerical experiments validate the proposed algorithm’s efficacy in enhancing efficiency and ensuring solution quality.

关键词： Automated terminals multi-AGV multi-agent path finding(MAPF) conflict based search(CBS) AGV path planning

Hot Compression Behavior and Tensile Property of a Novel Ni-Co-Based Superalloy Prepared by Electron Beam Smelting Layered Solidification Technology

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 283-292页

作者： Yong-Chao Gai Rui Zhang chuan-Yong Cui Zi-Jian zhou Yi Tan Yi-zhou zhou Xiao-Feng Sun Key Laboratory of Materials Modification by Laser Ionand Electron Beams(Ministry of Education)School of Materials Science and EngineeringDalian University of TechnologyDalian116024China Shi-Changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang110016China

The hot compression behavior and tensile strength after compression of a new Ni-Co-based superalloy produced using electron beam smelting layered(EBSL)solidification technology were *** compression tests were performed at temperatures of 1120℃and 1150℃,with strain rates of 1 s^(-1) and 0.01 s^(-1),reaching a true strain of *** strength was evaluated at room *** results revealed that this EBSL technology accelerates dynamic recrystallization(DRX),without compromising the strength of alloy.A significant correlation between the volume fraction of DRX and the strain rate was observed,with higher fractions at lower strain rates,leading to higher tensile ***,at the same strain rate,the specimens compressed at 1120℃exhibited higher tensile strength due to undissolvedγ′*** solution and aging heat treatment,the alloy maintained high tensile *** results suggested that the EBSL Ni-Co-based superalloy offers excellent prospects for practical applications.

关键词： Ni-Co-based superalloy Hot deformation Electron beam smelting Tensile strength

Modeling and Validation of Diamagnetic Rotor Levitated by Permanent Magnetics

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 224-235页

作者： Yuanping Xu Yue Zhang jin zhou Chaowu jin College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

As an innovative,low-power consuming,and low-stiffness suspension approach,the diamagnetic levitation technique has attracted considerable interest because of its potential applicability in miniaturized mechanical *** foundation of a diamagnetic levitation system is mathematical modeling,which is essential for operating performance optimization and stability ***,few studies on systematic mathematical modeling have been *** this study,a systematic mathematical model for a disc-shaped diamagnetically levitated rotor on a permanent magnet array is *** on the proposed model,the magnetic field distribution characteristics,diamagnetic levitation force characteristics(i.e.,levitation height and stiffness),and optimized theoretical conditions for realizing stable levitation are *** are conducted to verify the feasibility of the proposed mathematical *** predictions and experimental results indicate that increasing the levitation height enlarges the stable ***,with a further increase in the rotor radius,the stable regions of the rotor gradually diminish and even ***,when the levitation height is fixed,a moderate rotor radius permits stable *** study proposes a mathematical modeling method for a diamagnetic levitation system that has potential applications in miniaturized mechanical systems.

关键词： Diamagnetic levitation Magnetic levitation Rotor Modeling Validation Stability

Organic-inorganic hybrid piezotronic bipolar junction transistor for pressure sensing

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Microsystems & Nanoengineering 2024年第3期10卷 229-244页

作者： Emad Iranmanesh Zihao Liang Weiwei Li Congwei Liao Shunyu jin chuan Liu Kai Wang Shengdong Zhang Charalampos Doumanidis Gehan A.J.Amaratunga Hang zhou Guangdong Provincial Key Laboratory of In-Memory Computing Chips School of Electronic and Computer EngineeringPeking University Shenzhen Graduate SchoolShenzhen 518055P.R.China School of Mechanical Engineering Guangdong Technion-Israel Institute of TechnologyShantou 515063P.R.China State Key Laboratory of Microelectronics Device and Integrated Technology Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029P.R.China Hefei National Research Center for Physical Sciences at the Microscale University of Science and Technology of ChinaHefei 23000PR China School of Electronics and Information Technology Sun Yat-sen UniversityNo.132 East Waihuan RoadGuangzhou 510006P.R.China Department of Mechanical Aerospaceand Biomedical EngineeringUniversity of South AlabamaShelby Hall3128MobileAL 36688USA Electrical Engineering Division Department of EngineeringUniversity of Cambridge9 JJ Thomson AvenueCambridge CB30FAUnited Kingdom Zhejiang University International CampusHainingChina

With the rapid development of the Internet of Things(IoTs),wearable sensors are playing an increasingly important role in daily monitoring of personal health and *** signal-to-noise-ratio has become the most critical performance factor to *** enhance it,on the one hand,good sensing materials/devices have been employed;on the other hand,signal amplification and noise reduction circuits have been ***,most of these devices and circuits work in an active sampling mode,requiring frequent data acquisition and hence,entailing high-power *** this scenario,a flexible and wearable event-triggered sensor with embedded signal amplification without an external power supply is of great ***,we report a flexible two-terminal piezotronic n-p-n bipolar junction transistor(PBJT)that acts as an autonomous and highly sensitive,current-and/or voltage-mediated pressure *** PBJT is formed by two back-to-back piezotronic diodes which are defined as emitter-base and collectorbase *** force exertion on the emitter side,as a result of the piezoelectric effect,the emitter-base diode is forward biased while the collector-base diode is reverse *** to the inherent BJT amplification effect,the PBJT achieves record-high sensitivities of 139.7 kPa^(-1)(current-based)and 88.66 kPa^(-1)(voltage-based)in sensing *** PBJT also has a fast response time of<110 ms under exertion of dynamic stimuli ranging from a flying butterfly to a gentle finger ***,the PBJT advances the state of the art not only in terms of sensitivity but also in regard to being self-driven and autonomous,making it promising for pressure sensing and other IoT applications.

关键词： bipolar transistor IoT

Resonant Beam Communications:A New Design Paradigm and Challenges

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Journal of Communications and Information Networks 2024年第1期9卷 80-87页

作者： Yuanming Tian Dongxu Li chuan Huang Qingwen Liu Shengli zhou Future Network of Intelligence Institute and School of Science and Engineering the Chinese University of Hong KongShenzhen 518172China School of Science and Engineering and the Future Network of Intelligence Institute the Chinese University of Hong KongShenzhen 518172China College of Electronics and Information Engineering Tongji UniversityShanghai 201804China Department of Electrical and Computer Engineering University of ConnecticutStorrsCT 06250USA

Resonant beam communications (RBCom), which adopts oscillating photons between two separate retroreflectors for information transmission, exhibits potential advantages over other types of wireless optical communications (WOC). However, echo interference generated by the modulated beam reflected from the receiver affects the transmission of the desired information. To tackle this challenge, a synchronization-based point-to-point RBCom system is proposed to eliminate the echo interference, and the design for the transmitter and receiver is discussed. Subsequently,the performance of the proposed RBCom is evaluated and compared with that of visible light communications(VLC)and free space optical communications (FOC). Finally, future research directions are outlined and several implementation challenges of RBCom systems are highlighted.

关键词： resonant beam communications(RBCom) wireless optical communications(WOC) echo interference elimination mobility multiple access

Research on modeling and self-excited vibration mechanism in magnetic levitation-collision interface coupling system

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 873-890页

作者： jinghu TANG Chaofeng LI jin zhou Zhiwei WU School of Mechanical Engineering&Automation Northeastern UniversityShenyang 110819China Key Laboratory of Vibration and Control of Aero-Propulsion Systems of Ministry of Education of China Northeastern UniversityShenyang 110819China School of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

The modeling and self-excited vibration mechanism in the magnetic levitation-collision interface coupling system are *** effects of the control and interface parameters on the system's stability are *** frequency range of self-excited vibrations is investigated from the energy point of *** phenomenon of self-excited vibrations is elaborated with the phase *** corresponding control strategies are briefly analyzed with respect to the vibration *** results show that when the levitation objects collide with the mechanical interface,the system's vibration frequency becomes larger with the decrease in the collision gap;when the vibration frequency exceeds the critical frequency,the electromagnetic system continues to provide energy to the system,and the collision interface continuously dissipates energy so that the system enters the self-excited vibration state.

关键词： magnetic levitation coupling system self-excited vibration mechanical interface vibration frequency