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An insulinoma with clinical and electroencephalographic features resembling complex partial seizures

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第6期9卷 496-499页

作者： Shuang wang Hai-tao HU Shu-qun WEN Zhong-jin wang bao-rong ZHANG Mei-ping DING Department of Neurology the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

We described a female patient with insulinoma who experienced recurrent episodes of automatism, confusion and convulsion. Furthermore, her electroencephalography （EEG） findings resembled the pattern in complex partial seizures with secondary generalization. The interictal EEG showed spikes and sharp waves, as well as focal slowing over the left temporal lobe, and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing. She was initially misdiagnosed as pharmacoresistant epilepsy. After the insulinoma was found and surgically removed, her EEG turned normal and she was seizure-free during the 4-year follow-up. This report highlights the need for careful reassessment of all seizures refractory to medication, even for the oatients associated with eoileotiform discharges on EEG.

关键词： Insulinoma Hypoglycemia Electroencephalography (EEG) Seizure

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： jin-Peng wang Guo-Cui Mao Hui-Lin Jiang bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Research on solubilization used for micellar enhanced ultrafiltration

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Journal of Environmental Science and Engineering 2009年第3期3卷 1-6,36页

作者： XU jin ZHAO bao-wei wang Hai-feng CHE Hai-li School of Environmental and Municipal Engineering Lanzhou Jiaotong University Lanzhou 730070 China

Micellar enhanced ultrafiltration （MEUF） is a new effective treatment technology for the filtration removal of organic pollutants through solubilization. The present paper is aimed to study the solubilization of organic compounds such as chlorobenzene （CB）, pyrene and phenol by anionic, cationic and mixed anionic-nonionic surfactants such as sodium dodecyl sulfate （SDS）, cetyltrimethylammonium bromide （CTMAB） and Tween-80 （TW80） and the mixed SDS-TW80 with a batch equilibrium method. This study enables us to supply deeper investigation for MEUF. The results showed that solubilization capacity was not obvious below the critical micellar concentration （CMC）. The apparent solubilities of organic compounds were linearly related to surfactant concentrations over their CMCs. Solubilization capacity by single surfactants follow the order of TW80 〉 CTMAB 〉 SDS. The results also proved that the solubilization of the organic contaminants by the mixed surfactants can significantly be enhanced compared with the single anionic surfactant SDS. Whereas the CMC can be decreased, the solubility can be increased as long as the mass ratio of nonionic surfactant increases. The solubility enhancement efficiency of the different organic compounds follow the order of phenol 〉 CB 〉 pyrene. In addition, the solubilization ratio appears to be positively relative to the intrinsic water solubility of the organic contaminants and negatively correlates to octanol-water coefficients （Kow） of organic compounds and the hydrophile-lypophile balance values （HLB） of the surfactants.

关键词： micellar enhanced ultrafiltration surfactants solubilization

Revisit on analytical solution of Cattaneo equation including volumetric source in relation to laser short pulse heating

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Revisit on analytical solution of Cattaneo equation includin...

Biodiversity variability of macrobenthic in the Yellow Sea and East China Sea between 2001 and 2011

第十一届南方计算力学学术会议（SCCM-11）

作者： Guang-Ying Xu jin-bao wang Meiling Tian School of Maritime and Civil Engineering Zhejiang Ocean University

In this paper, Eq.(1) in Ref.[1] is corrected by pointing out the missing time derivative item of Fg(x)τδdf/dt. Based on the corrected Cattaneo heat conduction model, the analytical solutions of temperature and thermal stress fields are presented with the same initial and boundary conditions as those in Ref.[1]. The effects of the relaxation time τ on the temperature and thermal stress fields are shown graphically and discussed with or without the missing time derivative item of Fg(x)τδdf/dt. It can be founded that the corrected model will give the reasonable results which are consistent with the physical mechanism of micro-scale heat conduction as compared to the model in Ref.[1].

关键词： Cattaneo heat conduction model Temperature field Thermal stress field

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Zoological Systematics 2014年第4期39卷 459-484页

作者： Xin-Zheng Li Hong-Fa wang jin-bao wang Dong Dong Lin Ma Qi Kou Ji-Xing Sui Zhi-Bin Gan bao-Lin Zhang Institute of Oceanology Chinese Academy of Sciences

In this study, we compared the biodiversity and ecological status of macrobenthos between 2001 and 2011 in terms of species composition, dominant species, abundance, biomass, diversity, and secondary productivity of macrobenthos in the Yellow Sea and East China Sea. The results indicate that the species abundances, biomass, and diversity in spring 2011 were all lower than those in autumn 2000 and spring of 2001. Most of the dominant species have changed from 2001 to 2011, with the exception of the echinoderm Ophiura sarsii vadicola that was dominant in these years. Small-sized animal species have increased possibly due to gradual environment deterioration such as the pollution and the climate warmer.

关键词： Yellow Sea East China Sea macrobenthos ecology biodiversity secondary productivity

Systematic review and Meta-analysis of efficacy and safety of dienogest in treatment of endometriosis

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World Journal of Meta-Analysis 2021年第4期9卷 377-388页

作者： Shao-Chong Lin Xin-Yue wang Xi-Ling Fu Wen-Hui Yang Han Wu Yang Bai Zhong-Na Shi Jun-Peng Du bao-jin wang Department of Gynecology The Third Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Pharmacy Department The Third Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Medical School of Zhengzhou University Zhengzhou 450052Henan ProvinceChina Department of Pediatric Surgery The Third Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina

BACKGROUND The quality of life of women with endometriosis is substantially adversely affected by the pelvic pain caused by this ***,the choice of medication for endometriosis remains controversial,and no drug has been clearly proven to be superior to *** To assess the efficacy and safety of dienogest,a synthetic progestin,in the treatment of women with painful symptoms of *** PubMed,EMBASE,the Cochrane Library,and the Web of Science databases were searched from their inceptions to January 21,2020 for randomized controlled trials(RCTs)that compared dienogest with other popular prescription drugs for the treatment of *** reviewers extracted the *** difference(MD)values and risk ratios(RRs)with 95%confidence intervals(CIs)were *** Ultimately,seven RCTs with a total of 1493 participants met the requirements for this *** was found to more effective than placebo in alleviating endometriosis-related pain(MD=-32.93,95%CI:-44.63 to-21.23),but led to a more significant decline in plasma estradiol concentrations than placebo(MD=-44.7,95%CI:-62.24 to-24.69).Dienogest was superior to gonadotropin-releasing hormone analogues(GnRH-a)in relieving pain(MD=-2.41,95%CI:-3.58 to-1.24).Moreover,compared with dienogest,GnRH-a were significantly more likely to lead to the loss of bone mineral density(MD=2.77,95%CI:0.16 to 5.37)and were significantly associated with a higher incidence of headaches(RR=0.68,95%CI:0.52 to 0.91)and hot flushes(RR=0.43,95%CI:0.18 to 1.02).CONCLUSION This meta-analysis demonstrated that dienogest may be a better pain-relief treatment for endometriosis patients,due to its high efficacy and tolerability.

关键词： Dienogest Gonadotrophin-releasing hormone analogues Meta-analysis Endometriosis Medication

Analysis on the Quality of Cosmetics Tested in Xiamen City during 2005 to 2009

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Analysis on the Quality of Cosmetics Tested in Xiamen City d...

彩色多普勒超声监测子宫螺旋动脉血流与早期先兆流产预后的关系

2010 the 5th International Academic Conference on Environmental and Occupational Medicine

作者： HUANG Xiao-jin,wang bao-zhen,BAI Hong Xiamen Center for Disease Control and Prevention,Xiamen 361021,Fujian,China

[Objective]To provide evidence-based advice for supervision and regulation by analyzing the status quo and trends of cosmetic quality in Xiamen from 2005 to 2009.[Methods]In accordance with the"Hygiene Regulation for Cosmetics"by Ministry of Health,820 cosmetic samples in Xiamen were tested and analyzed for the indicators such as concentrations of Pb,As and Hg,total bacteria count,and number of Staphylococus aureus,Pseudomonas aerugiouosa,fungi and *** strains in feces.[Results]The qualification rate of cosmetics increased from 88.41%in 2005 to 100%(χ=14.35,P<0.010) in *** was a statistically significant difference,which showed that the quality of cosmetics was improved year by *** was found the obvious difference between qualification rates of cosmetics from three different sources(χ =100.82,P<0.005).The products at beauty salons had serious problem.37.33%of the products were tested with exceeding level of Hg,even some concentrations reached 94000mg/kg,whieh was tens of thousand times higher that the national limits.[Conclusion]The priority of inspection should be transferred to beauty *** it is necessary to strengthen daily surveillance and spot check,and enhance the training of practitioners.

关键词： cosmetic hygiene quality testing

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中国全科医学 2017年第9期20卷 1132-1135页

作者：王宝金王新月付喜玲王蒙蒙李霞罗真郑州大学第三附属医院河南省郑州市450000 河南省中医院河南省郑州市450052

目的探讨彩色多普勒超声监测早期先兆流产患者子宫螺旋动脉血流指标与其预后的关系。方法选择2015年7月—2016年1月在郑州大学第三附属医院门诊就诊的孕5~8周早期先兆流产妇女114例为研究组(A组),选择同期正常早期宫内妊娠妇女63例为对... 详细信息

目的探讨彩色多普勒超声监测早期先兆流产患者子宫螺旋动脉血流指标与其预后的关系。方法选择2015年7月—2016年1月在郑州大学第三附属医院门诊就诊的孕5~8周早期先兆流产妇女114例为研究组(A组),选择同期正常早期宫内妊娠妇女63例为对照组(B组),均行经腹彩色多普勒超声测量子宫螺旋动脉血流指标:收缩期峰值流速(S)、舒张末期流速(D)、S/D、搏动指数(PI)、阻力指数(RI)。A组与B组均随访至孕16周,A组患者中保胎失败者归入A1组(58例),保胎成功者则归入A2组(56例),B组中排除难免流产者8例后为55例。比较各组子宫螺旋动脉血流指标。结果 3组子宫螺旋动脉D、S/D、PI、RI比较,差异均有统计学意义(P0.05)。结论子宫螺旋动脉血流指标与早期先兆流产患者的预后有一定关系,可以通过监测早期先兆流产患者的子宫螺旋动脉血流情况指导保胎治疗。

关键词：流产,先兆超声检查,多普勒,彩色子宫螺旋动脉血流

药用复合辅料甘露醇-交联聚维酮的制备及质量评价

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药物分析杂志 2017年第4期37卷 724-731页

作者：金一宝王思明鲁艺殷果王珏王铁杰深圳药品质量标准研究重点实验室深圳市药品检验研究院深圳518057

目的:制备新型的功能性复合辅料甘露醇-交联聚维酮(Man-Cro),并对其进行质量评价。方法:通过处方组成与制备工艺的考察,对该辅料进行了质量标准研究与休止角、卡尔指数等辅助性功能研究,并进行压片试验比较。结果:以共同结晶法为工艺,... 详细信息

目的:制备新型的功能性复合辅料甘露醇-交联聚维酮(Man-Cro),并对其进行质量评价。方法:通过处方组成与制备工艺的考察,对该辅料进行了质量标准研究与休止角、卡尔指数等辅助性功能研究,并进行压片试验比较。结果:以共同结晶法为工艺,确定其处方组成为甘露醇-交联聚维酮为80:20,平均粒径为251μm,休止角小于40°,卡尔指数在22%~25%之间,该复合辅料具有良好的膨胀度、流动性、可压性以及崩解性,同时符合中国药典对甘露醇及交联聚维酮的质量要求,适用于口崩片的制备。结论:功能性复合辅料Man-Cro制备工艺简单可行,性能优良,可应用于直压性口崩片的制备,质量可控。

关键词：甘露醇交联聚维酮复合辅料口腔崩解片质量评价直接压片