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国防科技大学学报 1982年第2期 65-69页

作者：金昭廷谢淑云彭传才

本文着重阐述了离子镀锡——铟氧化物的原理,主要技术条件及其相互关系,最佳技术条件的选择与控制。还介绍了离子镀锡——铟氧化物的实验结果。

关键词：镀锡离子镀透射率空室气压化学镀氧化物薄膜离子

Bending Stiffness of Concrete-Filled Steel Tube and Its Influence on Concrete Placement Timing of Composite Beam-String Structure

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Structural Durability & Health Monitoring 2025年第1期19卷 55-75页

作者： Zhenyu Zhang Quan jin Haitao Zhang zhao Liu Yuyang Wu Longfei Zhang Renzhang Yan CCCC Third Highway Engineering Co. Ltd.Beijing101300China School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China

When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the *** order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during construction,the influence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefficient on the bending stiffness are analyzed parametrically by the numerical simulation technology based on an actual *** calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical ***,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction ***,the optimal construction plan of concrete placement first and then prestress-tensioning is proposed.

关键词： Concrete panels freeze-thaw damage compression-shear crack tension-shear crack

Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： Jie jin Huajing Zhang Qianying Lu Linqiang Tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia Lu Sijia Tian Yanmei zhao Wenjie Ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina Clinical Medical Center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health Central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina School of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review focuses on the use of nanocarrier systems for the efficient and precise delive ry of siRNAs,discussing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can precisely"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic strategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

Pave the way to the batch production of SWNT arrays for carbonbased electronic devices

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Nano Research 2023年第11期16卷 12516-12530页

作者： Ying xie Yue Li Ziqiang zhao jin Zhang College of Chemistry and Molecular Engineering Beijing Science and Engineering Center for NanocarbonsBeijing National Laboratory for Molecular SciencesPeking UniversityBeijing 100871China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

Single-walled carbon nanotubes(SWNTs)have been regarded as one of the most promising candidates to supplement or even replace silicon in the post-Moore *** requirement is to prepare the horizontally aligned SWNTs arrays(HASAs)with multiple indicators,including high density,high semiconducting purity,and wafer-scale ***,after all the fevered works being done in controlled synthesis,we still have a long way to go before realizing the application of SWNTs in highly performed electronic *** methods of batch production and high-throughput characterization techniques of the HASAs are the two main *** this outlook,we first summarized the progresses in synthesis of HASAs with either high density or high semiconducting *** the methods adopted in characterizing SWNTs and HASAs were discussed according to the different principles of characterization ***,the development of carbon nanotube based electronic devices,specifically,the field effect transistors(FETs),was reviewed from three *** problems involved in electronic applications bring forward the higher request to the HASAs ***,in the end of this outlook,we prospected the future of the synthesis and corresponding characterization of HASAs,and tried to provide our ideas about how to pave the way to the batch production of HASAs for carbon based electronic devices.

关键词： horizontally aligned carbon nanotubes batch production high-throughput characterization electronic application

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一种新的钢塑复合管制造技术

聚氯乙烯 2004年第6期32卷 27-32页

作者：赵劲松谢世雄广东顾地塑胶股份有限公司广东顺德528303

介绍了一种新的钢塑复合管连续制造技术,其特点是:在钢带焊接成管时通入惰性气体进行冷却,将焊道温度降低到PVC分解温度以下,从而避免与之粘连的PVC树脂分解。由于采用了冷却的方式,焊接部位与两管结合部位的距离可以缩短,减少了挤出压... 详细信息

介绍了一种新的钢塑复合管连续制造技术,其特点是:在钢带焊接成管时通入惰性气体进行冷却,将焊道温度降低到PVC分解温度以下,从而避免与之粘连的PVC树脂分解。由于采用了冷却的方式,焊接部位与两管结合部位的距离可以缩短,减少了挤出压力,提高了挤出速度;可以缩短芯棒和口模的距离,使二者易于调节同心,挤出的管材的壁厚均匀。由于冷却的惰性气体中不含氧,焊接管不会产生粗糙易脱落的氧化膜,两管复合时不会因此处的薄弱环节而分层。

关键词：聚氯乙烯钢塑复合管制造技术

China's Energy Consumption Forecasting by GMDH Based Auto-Regressive Model

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Journal of Systems Science & Complexity 2017年第6期30卷 1332-1349页

作者： xie Ling XIAO jin HU Yi zhao Hengjun XIAO Yi Business School Sichuan University School of Economics and Management University of Chinese Academy of Sciences School of Economics and Management Sichuan Radio and TV University School of Information Management Central China Normal University

It is very significant for us to predict future energy consumption accurately. As for China's energy consumption annual time series, the sample size is relatively small. This paper combines the traditional auto-regressive model with group method of data handling(GMDH) suitable for small sample prediction, and proposes a novel GMDH based auto-regressive(GAR) model. This model can finish the modeling process in self-organized manner, including finding the optimal complexity model, determining the optimal auto-regressive order and estimating model parameters. Further, four different external criteria are proposed and the corresponding four GAR models are constructed. The authors conduct empirical analysis on three energy consumption time series, including the total energy consumption, the total petroleum consumption and the total gas consumption. The results show that AS-GAR model has the best forecasting performance among the four GAR models, and it outperforms ARIMA model, BP neural network model, support vector regression model and GM(1, 1) ***, the authors give the out of sample prediction of China's energy consumption from 2014 to 2020 by AS-GAR model.

关键词： Auto-regressive model energy demand prediction GMDH small sample forecasting

Experimental Investigation of the Resistance Performance and Heave and Pitch Motions of Ice-Going Container Ship Under Pack Ice Conditions

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China Ocean Engineering 2018年第2期32卷 169-178页

作者： GUO Chun-yu xie Chang ZHANG jin-zhao WANG Shuai zhao Da-gang College of Shipbuilding Engineering Harbin Engineering UniversityHarbin 150001China Nantong COSCO KHI Ship Engineering Co.Ltd Nantong 226005China Shanghai Marine Equipment Research Institute Shanghai 200031China

In order to analyze the ice-going ship’s performance under the pack ice conditions, synthetic ice was introduced into a towing tank. A barrier using floating cylinder in the towing tank was designed to carry out the resistance experiment. The test results indicated that the encountering frequency between the ship model and the pack ice shifts towards a high-velocity point as the concentration of the pack ice increases, and this encountering frequency creates an unstable region of the resistance, and the unstable region shifts to the higher speed with the increasing concentration. The results also showed that for the same speed points, the ratio of the pack ice resistance to the open water resistance increases with the increasing concentration, and for the same concentrations, this ratio decreases as the speed increases. Motion characteristics showed that the mean value of the heave motion increases as the speed increases, and the pitch motion tends to increase with the increasing speed. In addition, the total resistance of the fullscale was predicted.

关键词： synthetic ice pack ice concentration heave pitch peak collision value

人脐带间充质干细胞条件培养基及外泌体对肝癌细胞增殖、迁移、侵袭和凋亡的影响

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中国组织工程研究 2025年第7期29卷 1350-1355页

作者：金凯唐婷李美乐谢裕安广西中医药大学研究生院广西壮族自治区南宁市530002 广西壮族自治区妇幼保健院广西壮族自治区南宁市530002 广西出生缺陷及干细胞生物样本库重点实验室广西壮族自治区南宁市530002

背景:间充质干细胞可通过分泌含细胞因子、生长因子和外泌体的细胞外囊泡调节肿瘤微环境,对肿瘤细胞生物学行为进行精准调控。目的:研究人脐带间充质干细胞条件培养基及外泌体对肝癌细胞生物学特性的影响。方法:收集人脐带间充质干细胞... 详细信息

背景:间充质干细胞可通过分泌含细胞因子、生长因子和外泌体的细胞外囊泡调节肿瘤微环境,对肿瘤细胞生物学行为进行精准调控。目的:研究人脐带间充质干细胞条件培养基及外泌体对肝癌细胞生物学特性的影响。方法:收集人脐带间充质干细胞培养上清,通过高速离心并过滤获得人脐带间充质干细胞条件培养基;收集人脐带间充质干细胞培养上清,通过超高速梯度离心法提取人脐带间充质干细胞外泌体。使用PKH26标记人脐带间充质干细胞外泌体,与肝癌细胞MHCC97-H共培养,荧光显微镜观察MHCC97-H细胞摄取外泌体情况。通过CCK-8增殖实验、Transwell迁移和侵袭实验以及流式凋亡实验评估人脐带间充质干细胞条件培养基、人脐带间充质干细胞外泌体对肝癌细胞生物学功能的影响。结果与结论:(1)人脐带间充质干细胞外泌体可被MHCC97-H细胞摄取且主要分布于细胞质中;(2)人脐带间充质干细胞条件培养基处理后,MHCC97-H细胞的增殖、迁移和侵袭能力显著增强(P<0.001,P<0.05,P<0.01),凋亡能力显著下降(P<0.001);而人脐带间充质干细胞外泌体处理后,MHCC97-H细胞的增殖能力下降(P<0.001),迁移、侵袭及凋亡能力显著增强(P<0.001);(3)结果表明,人脐带间充质干细胞条件培养基具有促进MHCC97-H细胞增殖、迁移、侵袭和抑制凋亡的能力;而人脐带间充质干细胞外泌体则具有促进MHCC97-H细胞迁移、侵袭及凋亡和抑制增殖的能力。

关键词：肝癌人脐带间充质干细胞外泌体条件培养基增殖迁移侵袭凋亡

Unraveling the significance of cobalt on transformation kinetics, crystallography and impact toughness in high-strength steels

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International Journal of Minerals,Metallurgy and Materials 2025年第02期 380-390页

作者： Yishuang Yu jingxiao zhao Xuelin Wang Hui Guo Zhenjia xie Chengjia Shang Collaborative Innovation Center of Steel Technology University of Science and Technology Beijing School of Materials Science and Engineering Shanghai Jiao Tong University State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing

This work reveals the significant effects of cobalt(Co) on the microstructure and impact toughness of as-quenched highstrength steels by experimental characterizations and thermo-kinetic analyses. The results show that the Co-bearing steel exhibits finer blocks and a lower ductile–brittle transition temperature than the steel without Co. Moreover, the Co-bearing steel reveals higher transformation rates at the intermediate stage with bainite volume fraction ranging from around 0.1 to 0.6. The improved impact toughness of the Co-bearing steel results from the higher dense block boundaries dominated by the V1/V2 variant pair. Furthermore, the addition of Co induces a larger transformation driving force and a lower bainite start temperature(BS), thereby contributing to the refinement of blocks and the increase of the V1/V2 variant pair. These findings would be instructive for the composition, microstructure design, and property optimization of high-strength steels.

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单原子Pt负载在锐钛矿(001)表面的电光学特性研究

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原子与分子物理学报 2025年第6期42卷 43-50页

作者：靳帆赵志超运城学院应用化学系运城044000 运城学院科研产业部运城044000

基于第一性原理的多体格林函数理论方法,系统探究了锐钛矿TiO_(2)(001)表面负载Pt单原子催化剂的电子结构和光学性质,考虑Pt在完美表面和缺陷表面(O空位)两种基底上的负载.结果发现,Pt会在TiO_(2)禁带中间、价带和导带边缘引入新能级,... 详细信息

基于第一性原理的多体格林函数理论方法,系统探究了锐钛矿TiO_(2)(001)表面负载Pt单原子催化剂的电子结构和光学性质,考虑Pt在完美表面和缺陷表面(O空位)两种基底上的负载.结果发现,Pt会在TiO_(2)禁带中间、价带和导带边缘引入新能级,但不同基底负载的Pt单原子催化剂存在不同的带隙特性.Pt的负载会引起体系光学吸收红移,增大光学吸收范围,延伸光吸收至可见光甚至是红外区域,提升可见光活化的可能性,同时改善体系的激子束缚能,有利于空穴与电子有效分离,这可能是Pt负载后光催化性能提升的原因之一.然而,若在可见光或低能量紫外光激发后,分离的电子与空穴没有及时参与反应,体系衰变回最低激发态,此时极大的激子束缚能可能会加速电子与空穴重组,不利于表面催化反应的进行.负载在O空位的催化剂最低激发态的激子束缚能比完美表面小,重组速率慢.计算结果能够为理解单原子催化剂结构-性能关系提供一些见解.

关键词：二氧化钛 Pt单原子催化剂多体格林函数理论电子结构光吸收