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Effects of dietary supplementation of Bacillus subtilis DSM 32315 on growth,immune response and acute ammonia stress tolerance of Nile tilapia(Oreochromis niloticus)fed with high or low protein diets

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Animal Nutrition 2023年第4期15卷 375-385页

作者： Zhihong Liao Yantao Liu Hanlin wei Xuanshu He Ziqiao Wang Zhenxiao Zhuang wei Zhao Karthik Masagounder Juyun He jin niu State Key Laboratory of Biocontrol Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)School of Life SciencesSun Yat-sen UniversityGuangzhouChina Evonik Operations GmbH 63457 Hanau-WolfgangGermany Evonik(China)Co.Ltd. Guangzhou BranchGuangzhouChina School of Pharmaceutical Sciences Guangzhou Medical UniversityGuangzhouChina

Aquatic animals have benefited from Bacillus subtilis-based probiotics over the past few *** study evaluated the effects of *** DSM 32315 probiotics as a feed additive on growth,immune response and resistance to acute ammonia challenge in Nile ***,four supplemental levels(0%,0.1%,0.2%,and 0.3%)of *** probiotics were tested under two dietary protein levels(32%and28%).Five replicate tanks were randomly allotted to each dietary treatment,with each tank containing 30Nile *** 8 weeks of feeding,Nile tilapia in each tank were exposed to 43.61 mg/L of total ammonia nitrogen for 48 *** results revealed that reducing protein levels from 32%to 28%did not affect growth performance or antioxidant ***,the low protein diet tended to induce an inflammatory effect shown by increased expressions of TGF-βand IFN-γgenes(P<0.05)in the *** impact was alleviated by the probiotic *** with the non-supplemented group,0.1%probiotic supplementation remarkably increased plasma lysozyme activity,total antioxidant capacity and complement C3 and interleukin-10 mRNA levels(P<0.05)in the 28%protein diet,while higher supplementation of probiotics(0.3%)was shown to be beneficial for the high protein diet(32%).In both the dietary protein levels,0.1%supplementation of probiotics promoted the antioxidant capacity of Nile tilapia before exposure to ammonia stress but higher probiotic supplementation(0.3%)proved to be necessary under ammonia stress as evidenced by higher fish survival *** exhibited that supplementation with *** probiotics had a better effect on the intestinal morphology(villi height and width)regardless of protein *** conclusion,dietary supplementation of *** DSM 32315probiotics at 0.1%in the low protein diet and up to 0.3%in the high protein diet showed beneficial effects on the growth,immunity,and antioxidant capacity of Nile *** ammonia stress conditions,th

关键词： Bacillus subtilis probiotics Nile tilapia Acute ammonia challenge Antioxidant capacity

Fast division-free parallel structure for convolution perfectly matched layer in finite difference time domain method

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The Journal of China Universities of Posts and Telecommunications 2015年第1期22卷 72-76,82页

作者： Bai Bing niu Zhongqi niu Yi wei Bing Zhao Gang School of Electronic Engineering Xidian University School of Physics and Optoelectronic Engineering Xidian University

Parallel acceleration of convolution perfectly matched layer （CPML） algorithm suffers from massive division operation which is widely accepted as one of the most expensive operations for the equipment such as graphic processing unit （GPU）, field programmable gate array （FPGA） etc. In pursuit of higher efficiency and lower power consumption, this article revisited the CPML theory and proposed a new fast division-free parallel CPML structure. By optimally rearranging the CPML inner iteration process, all the division operators can be eliminated and replaced by recalculating the related field updating coefficients offline. Experiments show that the proposed division-free structure can save more than 50% arithmetic instructions and 25% execution time of the traditional parallel CPML structure without any accuracy loss.

关键词： division elimination convolution perfectly matched layer finit difference time domain parallel computing graphic processing unit

Influences of Long-Term Fertilizer and Tillage Management on Soil Fertility of the North China Plain

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Pedosphere 2011年第6期21卷 813-820页

作者： niu Ling-An HAO jin-Min ZHANG Bao-Zhong niu Xin-Sheng Quzhou Experimental Station China Agricultural University Quzhou 057250 （China）

In the North China Plain, fertilizer management and tillage practices have been changing rapidly during the last three decades; however, the influences of long-term fertilizer applications and tillage systems on fertility of salt-affected soils have not been well understood under a winter wheat (Triticum aestivum L.)-maize (Zea mays L.) annual double cropping system. A field experiment was established in 1985 on a Cambosol at the Quzhou Experimental Station, China Agricultural University, to investigate the responses of soil fertility to fertilizer and tillage practices. The experiment was established as an orthogonal design with nine treatments of different tillage methods and/or fertilizer applications. In October 2001, composite soil samples were collected from the 0–20 and 20–40 cm layers and analyzed for soil fertility indices. The results showed that after 17 years of nitrogen (N) and phosphorous (P) fertilizer and straw applications, soil organic matter (SOM) in the top layer was increased significantly from 7.00 to 9.30–13.14 g kg-1 in the 0–20 cm layer and from 4.00 to 5.48–7.75 g kg-1 in the 20–40 cm layer. Soil total N (TN) was increased significantly from 0.37 and 0.22 to 0.79–1.11 and 0.61–0.73 g N kg-1 in the 0–20 and 20–40 cm layers, respectively, with N fertilizer application; however, there was no apparent effect of straw application on TN content. The amounts of soil total P (TP) and rapidly available P (RP) were increased significantly from 0.60 to 0.67–1.31 g kg-1 in the 0–20 cm layer and from 0.52 to 0.60–0.73 g kg-1 in the 20–40 cm layer with P fertilizer application, but were decreased with combined N and P fertilizer applications. The applications of N and P fertilizers significantly increased the crop yields, but decreased the rapidly available potassium (RK) in the soil. Straw return could only meet part of the crop potassium requirements. Our results also suggested that though some soil fertility parameters were maintained or enhanced unde

关键词： rapidly available K rapidly available P soil organic matter straw return total N

Cost-benefit analysis of esophageal cancer endoscopic screening in high-risk areas of China

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World Journal of Gastroenterology 2012年第20期18卷 2493-2501页

作者： Juan Yang wen-Qiang wei jin niu Zhi-Cai Liu Chun-Xia Yang You-Lin Qiao Department of Epidemiology West China School of Public Health Sichuan University Chengdu 610041 Sichuan Province China Department of Epidemiology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China Department of Thoracic-Surgery Linzhou Cancer Institute Linzhou 456550 Henan Province China

AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and the benefit-cost ratios(BCRs)of 12 EC endoscopic screening *** varied according to the targeted screening age,screening frequencies,and follow-up *** parameters were collected from population-based studies in China,published literatures,and surveillance data. RESULTS:Compared with non-screening outcomes,all strategies with hypothetical 100 000 subjects saved life *** five dominant strategies determined by the incremental cost-effectiveness analysis,screening once at age 50 years incurred the lowest NPV(international dollar-I$55 million)and BCR(2.52).Screening six times between 40-70 years at a 5-year interval[i.e., six times(40)f-strategy]yielded the highest NPV(I$99 million)and BCR(3.06).Compared with six times(40)fstrategy,screening thrice between 40-70 years at a 10-year interval resulted in relatively lower NPV,but the same BCR. CONCLUSION:EC endoscopic screening is cost-beneficial in high-risk areas of ***-makers should consider the cost-benefit,population acceptance,and local economic status when choosing suitable screening strategies.

关键词： Cost-benefit analysis Esophageal cancer Endoscopy Screening High-risk area

RNA interference in insects:the link between antiviral defense and pest control

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Insect Science 2024年第1期31卷 2-12页

作者： jinzhi niu Ruoyu Chen jin-Jun Wang Key Laboratory of Entomology and Pest Control Engineering College of Plant ProtectionSouthwest UniversityChongqingChina Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River(Ministry of Education) Southwest UniversityChongqingChina

RNA interference(RNAi)is a form of gene silencing triggered by double-stranded RNA(dsRNA)that operates in all eukaryotic *** has been widely investigated in insects to determine the underlying molecular mechanism,to investigate its role in systemic antiviral defense,and to develop strategies for pest *** insect cells are infected by viruses,viral dsRNA signatures trigger a local RNAi response to block viral replication and generate virus-derived DNA that confers systemic ***-based insect pest control involves the application of exogenous dsRNA targeting genes essential for insect development or survival,but the efficacy of this approach has limited potency in many pests through a combination of rapid dsRNA degradation,inefficient dsRNA uptake/processing,and ineffective RNAi *** could be addressed by dsRNA screening and evaluation,focusing on dsRNA design and off-target management,as well as dsRNA production and *** review summarizes recent progress to determine the role of RNAi in antiviral defense and as a pest control strategy in insects,addressing gaps between our fundamental understanding of the RNAi mechanism and the exploitation of RNAi-based pest control strategies.

关键词： RNAi response systemic RNAi insecticidal dsRNA biological control off-targets

Formation of coherent BCC/B2 microstructure and mechanical properties of Al-Ti-Zr-Nb-Ta-Cr/Mo light-weight refractory high-entropy alloys

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Rare Metals 2022年第8期41卷 2886-2893页

作者： Dong-Ming jin Zhen-Hua Wang jin-Feng Li Ben niu Qing Wang Engineering Research Center of High Entropy Alloy Materials(Liaoning Province) Key Laboratory of Materials Modification by LaserIon and Electron Beams(Ministry of Education)School of Materials Science and EngineeringDalian University of TechnologyDalian116024China Institute of Materials China Academy of Engineering PhysicsMianyang621908China

The present work investigated the formation of coherent body-centered-cubic(BCC)/B2 microstructure in Al-Ti-Zr-Nb-Ta-Cr/Mo refractory high-entropy alloy system,in which three alloys with the composition of Al_(2)Ti_(6) Zr_(2)Nb_(3)Ta_(2)(Cr/Mo)_(1)were *** as-cast alloy ingots were homogenized at 1573 K for 2 h and then aged at different temperatures for 24 *** is found that the BCC/B2 coherent microstructure with cuboidal BCC nanoprecipitates into the B2 matrix would be formed in873 K-aged Al_(2)Ti_(6) Zr_(2)Nb_(3)Ta_(2)Cr_(0.5)Mo_(0.5)alloy with half Cr and half Mo,which is ascribed to a moderate lattice misfit(ε=0.94%)between BCC and B2 *** is due to the special coherent microstructure that results in a prominent mechanical property with the highest compressive yield strength(σ_(YS)=1314 MPa)and good plasticity among these alloys,while coarse Cr2 Ti and Zr_(5)Al_(3)particles are existed in 873 K-aged alloy with *** 1073 K aging,all these alloys with Cr_(1),Cr_(0.5)Mo_(0.5)and Mo_(1)consist of BCC,B2 and Zr_(5)Al_(3),in which BCC/B2 coherent microstructure is *** strengthening mechanism of BCC/B2 coherent microstructure in 873 K-aged alloy with Cr_(0.5)Mo_(0.5)was also discussed.

关键词： High entropy alloys Coherent precipitation Microstructure Lattice misfit Precipitation strengthening

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基于混合语义的切片级智能合约重入漏洞检测

计算机工程与应用 2025年第1期61卷 321-329页

作者：江姝晨牛保宁高彦太原理工大学计算机科学与技术学院山西晋中030600

针对现有基于深度学习的漏洞检测方法主要集中在源代码的单一表现形式上,无法完全捕获源代码中包含的丰富语义信息和结构信息,以及大多数方法基于函数粒度,检测样本存在大量与漏洞无关的冗余代码导致检测精度下降的问题,聚焦于智能合约... 详细信息

针对现有基于深度学习的漏洞检测方法主要集中在源代码的单一表现形式上,无法完全捕获源代码中包含的丰富语义信息和结构信息,以及大多数方法基于函数粒度,检测样本存在大量与漏洞无关的冗余代码导致检测精度下降的问题,聚焦于智能合约最严重的漏洞之一,即重入漏洞,提出一种基于混合语义的切片级智能合约重入漏洞检测方法SCHyVulDect。根据漏洞特征关键字对智能合约进行切片操作,获得合约切片;构建合约切片的代码图,通过图注意力网络(graph attention network,GAT)提取其深层语义信息。并使用双向长短期记忆网络(bidirectional long-short term memory,Bi-LSTM)和注意力机制,提取切片代码的上下文序列特征,将提取的图结构特征和序列特征进行融合,从而进行漏洞检测。实验结果表明,SCHyVulDect检测重入漏洞的精确率、召回率和F1值分别为96.36%、94.45%、91.70%,比现有的基于深度学习的智能合约漏洞检测方法的精确率提高13.03~18.00个百分点,具有较好的检测效果。

关键词：区块链智能合约漏洞检测图注意力网络混合语义

Review of some Siobla(Hymenoptera:Tenthredinidae)species

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Zoological Systematics 2021年第3期46卷 208-224页

作者： Gengyun niu Meicai wei College of Life Sciences Jiangxi Normal UniversityNanchang 330022China

Six Siobla species are revised,including the following new synonymies:*** wei,2002,***.,synonymized by *** Malaise,1931;*** wei,2002,***.,synonymized by *** Mallach,1933 and Encarsioneura similis Mocsáry,1909,***.,synonymized by ***(Gimmerthal,1834).*** Mocsáry,1909,as the synonym of ***(Klug,1817)was recovered;Siobla plesia *** regarded to be a valid species,rather than a subspecies of *** iridipennis Malaise,1934 is redescribed based on the holotype,and a new species group,Siobla iridipennis group,is *** characters of the group are briefly *** illustrations of type specimens mentioned in this paper are *** addition,the lectotypes of Encarsioneura similis Mocsáry,1909,Encarsioneura frigida Mocsáry,1909,and Siobla sturmii plesia Malaise,1945 are designated here.

关键词： Hymenoptera Tenthredinidae Siobla new synonyms redescription

Phase-field modeling of epitaxial growth with the Ehrlich-Schwoebel barrier: Model validation and application

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Science China(Technological Sciences) 2015年第4期58卷 753-762页

作者： DONG Xiang Lei XING Hui SHA Sha CHEN Chang Le niu Li wei WANG Jian Yuan jin Ke Xin Shanxi Key Laboratory for Condensed Matter Structure and Properties Department of Applied Physics Northwestern Polytechnical University

In this paper,we introduce different forms of mobility into a quantitative phase-field model to produce arbitrary Ehrlich-Schwoebel(ES)*** studies were carried out in the one-side step-flow model,which showed that the original mobility not only induces the ES effect,but also leads to larger numerical instability with increase of the step ***,another modified form of the ES barrier is proposed,and is found to be more suitable for large-scale *** applications were performed on the wedding-cake structure,coarsening and coalescence of islands and spiral *** results show that the ES barrier exhibits more significant kinetic effects at the larger deposition rates by limiting motions of atoms on upper steps,leading to aggregation on the top layers,as well as the roughening of growing surfaces.

关键词： epitaxial growth phase-field method Ehrlich-Schwoebel barrier kinetics interfacial