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Adjuvant percutaneous radiofrequency ablation of feeding artery of hepatocellular carcinoma before treatment

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World Journal of Gastroenterology 2009年第21期15卷 2638-2643页

作者： Yi-Bin Hou Min-Hua Chen Kun Yan jin-Yu Wu wei yang Ultrasound Department Peking University School of Oncology Cancer Hospital & Institute No. 52 Fucheng Road Haidian District Beijing 100142 China

AIM:To evaluate the feasibility and efficacy of percutaneous radiofrequency ablation(RFA) of the feeding artery of hepatocellular carcinoma(HCC) in reducing the blood-flow-induced heat-sink effect of ***:A total of 154 HCC patients with 177 pathologically confirmed hypervascular lesions participated in the study and were randomly assigned into two ***-one patients with 75 HCCs(average tumor size,4.3 ± 1.1 cm) were included in group A,in which the feeding artery of HCC was identified by color Doppler flow imaging,and were ablated with multiple small overlapping RFA foci [percutaneous ablation of feeding artery(PAA)] before routine RFA treatment of the ***-three patients with 102 HCC(average tumor size,4.1 ± 1.0 cm) were included in group B,in which the tumors were treated routinely with ***-enhanced computed tomography was used as post-RFA imaging,when patients were followed-up for 1,3 and 6 ***:In group A,feeding arteries were blocked in 66(88%) HCC lesions,and the size of arteries decreased in nine(12%).The average number of punctures per HCC was 2.76 ± 1.12 in group A,and 3.36 ± 1.60 in group B(P = 0.01).The tumor necrosis rate at 1 mo post-RFA was 90.67%(68/75 lesions) in group A and 90.20%(92/102 lesions) in group *** recur-rence rate at 6 mo post-RFA was 17.33%(13/75) in group A and 31.37%(32/102) in group B(P = 0.04).CONCLUSION:PAA blocked effectively the feeding artery of *** of PAA and RFA significantly decreased post-RFA recurrence and provided an alternative treatment for hypervascular HCC.

关键词： Hepatocellular carcinoma Feeding artery Radiofrequency ablation Recurrence Color Dopplerflow imaging

A novel primary culture method for high-purity satellite glial cells derived from rat dorsal root ganglion

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Neural Regeneration Research 2019年第2期14卷 339-345页

作者： Xian-Bin Wang wei Ma Tao Luo jin-wei yang Xiang-Peng Wang Yun-Fei Dai Jian-Hui Guo Li-Yan Li Institute of Neuroscience Kunming Medical University Medical Faculty Panzhihua University Second Department of General Surgery First People's Hospital of Yunnan Province

Satellite glial cells surround neurons within dorsal root ganglia. Previous studies have focused on single-cell suspensions of cultured neurons derived from rat dorsal root ganglia. At present, the primary culture method for satellite glial cells derived from rat dorsal root ganglia requires no digestion skill. Hence, the aim of the present study was to establish a novel primary culture method for satellite glial cells derived from dorsal root ganglia. Neonatal rat spine was collected and an incision made to expose the transverse protrusion and remove dorsal root ganglia. Dorsal root ganglia were freed from nerve fibers, connective tissue, and capsule membranes, then rinsed and transferred to 6-well plates, and cultured in a humidified 5% CO_2 incubator at 37°C. After 3 days in culture, some cells had migrated from dorsal root ganglia. After subculture, cells were identified by immunofluorescence labeling for three satellite glial cell-specific markers: glutamine synthetase, glial fibrillary acidic protein, and S100β. Cultured cells expressed glutamine synthetase, glial fibrillary acidic protein, and S100β, suggesting they are satellite glial cells with a purity of > 95%. Thus, we have successfully established a novel primary culture method for obtaining high-purity satellite glial cells from rat dorsal root ganglia without digestion.

关键词： nerve regeneration cell culture dorsal root ganglia immunofluorescence identification satellite glial cells neural regeneration

An Efficient Cationic Cyclization Approach for the Construction of Labdane Diterpenoid Decalin Ring Skeleton

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Chinese Chemical Letters 2005年第4期16卷 433-436页

作者： jin Hui yang, wei Dong Z. LI* State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 China

An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.

关键词： Allylsilane labdane skeleton cationic cyclization biomimetic synthesis.

Metal-film-assisted ultra-clean transfer of single-walled carbon nanotubes

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Nano Research 2014年第7期7卷 981-989页

作者： Yujun He Dongqi Li Tianyi Li Xiaoyang Lin jin Zhang yang wei Peng Liu Lina Zhang Jiaping Wang Qunqing Li Shoushan Fan Kaili Jiang State Key Laboratory of Low-Dimensional Quantum Physics Department of Physics & Tsinghua-Foxconn Nanotechnology ResearchCenter Tsinghua University Beijing 100084 China

Transfer printing of nanomaterials onto target substrates has been widely used in the fabrication of nanodevices, but it remains a challenge to fully avoid contamination introduced in the transfer process. Here we report a metal-film- assisted method to realize an ultra-clean transfer of single-walled carbon nanotubes （SWCNTs） mediated by poly（methyl methacrylate）（PMMA）. The amount of PMMA residue can be greatly reduced due to its strong physical adhesion to the metal film, leading to ultra-clean surfaces of both the SWCNTs and the substrates. This metal-film-assisted transfer method is efficient, nondestructive, and scalable. It is also suitable for the transfer of graphene and other nanostructures. Furthermore, the relatively low temperature employed allows this technique to be compatible with nanomaterial-based flexible electronics.

关键词： metal-film-assisted single-walled carbonnanotube transfer flexible substrate Schottky barrier

FEM simulation of formation of metamorphic core complex with ANSYS software

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Global Geology 2007年第1期10卷 110-112页

作者： Guoqing YIN wei jin Xianli yang College of Earth Sciences Jilin University Changchun 130061 China

This study utilizes ANSYS to establish FEM's model of metamorphic core complex,and used thermal-structure analysis to simulate metamorphic core complex's temperature field and stress *** metamorphic core complex formation mechanism is *** simulation results show that the temperature field change appearing as the earth surface's temperature is the lowest,and the temperature of metamorphic core complex's nucleus is the *** temperature field is higher along with depth increase,and the stress field change appearing as the biggest stress occurs in the *** next stress field occurs at the top of the cover.

关键词： ANSYS metamorphic core complex numerical simulation

Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke

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Neural Regeneration Research 2022年第6期17卷 1299-1309页

作者： wei Ma Chun-Yan Li Si-Jia Zhang Cheng-Hao Zang jin-wei yang Zhen Wu Guo-Dong Wang Jie Liu wei Liu Kuang-Pin Liu Yu Liang Xing-Kui Zhang Jun-Jun Li Jian-Hui Guo Li-Yan Li Institute of Neuroscience Kunming Medical UniversityKunmingYunnan ProvinceChina Second Department of General Surgery First People’s Hospital of Yunnan ProvinceKunmingYunnan ProvinceChina

During acute reperfusion,the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad ***,whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in rats remains *** this study,RNA isolation and library preparation was performed for long noncoding RNA sequencing,followed by determining the coding potential of identified long noncoding RNAs and target gene *** expression analysis,long noncoding RNA functional enrichment analysis,and co-expression network analysis were performed comparing ischemic rats with and without ischemic postconditioning *** were subjected to ischemic postconditioning via the brief and repeated occlusion of the middle cerebral artery or femoral *** real-time reverse transcription-polymerase chain reaction was used to detect the expression levels of differentially expressed long noncoding RNAs after ischemic postconditioning in a rat model of ischemic *** results showed that ischemic postconditioning greatly affected the expression profile of long noncoding RNAs and mRNAs in the brains of rats that underwent ischemic *** predicted target genes of some of the identified long noncoding RNAs(cis targets)were related to the cellular response to ischemia and stress,cytokine signal transduction,inflammation,and apoptosis signal transduction *** addition,15 significantly differentially expressed long noncoding RNAs were identified in the brains of rats subjected to ischemic *** candidate long noncoding RNAs that may be related to ischemic postconditioning were identified by a long noncoding RNA expression profile and long noncoding RNA-mRNA co-expression network *** levels were verified by quantitative real-time reverse transcription-polymerase chain *** results suggested that the identified long noncoding RNAs may be involved in the neuropr

关键词： cerebral infarction differential expression analysis expression profiling GO term ischemic postconditioning ischemic stroke KEGG pathway lncRNA mRNA RNA sequencing

Evolutionary Model to Traditional Culture and Program Organization

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International Journal of Plant Engineering and Management 2006年第3期11卷 158-165页

作者： ZHANG jing-xiao jin wei-xing yang De-qin School of Management Xi＇an University of Architecture and Technology Xi＇an 710055 P. R. China

To study the relationship between the evolutions of Chinese Traditional Culture （CTC） and program organization, an outline of the CTC is generalized by reviewing literature, and which is also compartmentalized into two aspects according to economic philosophy views： traditional philosophy aspect and value judgment. Based on three dimensions, which are the philosophy aspect （P）, program organization model （P）, and value judgment from economic philosophy views （ V）, and this evolution sequence, the CTC＇s influence on the program organization model in the evolution is discussed; then the cultural spatial evolution model for program organization based on the three dimensions （PPV） is constructed. From analyzing the plane matrix of P-P and empirical investigating on the organizational model of construction enterprises, it is found that the ancient Chinese government organizational model still has prevailing influence on the modern program organizational model in China.

关键词： traditional culture program organization value judgment managerial philosophy organizational evolution

CENOZOIC VOLCANISM AND LITHOSPHERETECTONIC EVOLUTION IN NORTH TIBET

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地学前缘 2000年第S1期7卷 153-154页

作者： Chi Xiaoguo, Li Cai, jin wei, Liu Shen, yang Rihong (Changchun University of Science and Technology,Changchun 130026, China)

Volcanism is the direct indication of the upper mantle thermodynamic activities, and it is an efficient path to study the lithosphere tectonic evolution. Cenozoic volcanism in North Tibet is of obviously time circles. In the space, from south to north, the chemical composition of volcanics changed from Na\|rich alkalic basaltic series formed 44Ma. ago into high\|K calcalkali series formed in about 40～*** Qiangtang area, into minor amount of leucite basalt and phonolite series of 26Ma., further into shoshonite series aged at 19～7Ma. in Cocoxili basin, until Quaternary shoshonite series in Karakunlun and Qilian Mt.\|Yumen region(Xiaoguo Chi etc.1999).Isotopes of Sr,Nd,Pb and trace elements in volcanic rocks provide wide range of information for the evolution of lithosphere in North Tibet after 45Ma. Present research shows that Na\|rich alkalic basalt series formed 44Ma. ago has the features of a primitive mantle in Sr,Nd,Pb isotopes. Along with the evolutionary tendency to high\|K calcalkali series and phonolite series, isotopes of Sr,Nd,Pb evolve towards EM2\|rich mantle end. The North Tibet is a compound continental mass combined from several terrains of different geological periods and the lithosphere mantle sees a complicated evolutionary history. Hence, the mixing of different rocks in ancient subduction zones and long history of metasomatism in the upper mantle offered excellent and favorable conditions for the formation of EM2 mantle end and for potassic enrichment. Isotopic evolutionary features indicate that the early magma came from the asthenosphere while later magmas were derived from partial remelting of lithosphere mantle.

关键词： volcanism evolution of lithosphere North Tibet

Studies on hypersensitive transitions of Nd(Ⅲ)in Nd(Ⅲ)-β-diketone-neutral ligand ternary compounds

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Chinese Journal of Chemistry 1993年第4期11卷 289-298页

作者： GAO, jin-Zhang yang,wei-Dong yang,Wu KANG,jing-Wan BAI,Guang-Bi Institute of Chemistry,Northwest Normal University,Lanzhou 730070YU,Geng-Sun Department of Physics,Northwest Normal University,Lanzhou 730070

In this paper,hypersensitive transitions of Nd(Ⅲ)in Nd(Ⅲ)-β-diketone-neutral ligand ternary coordination compounds(where β-diketone=acetylacetone(AA),benzoylace- tone(BA),dibenzoylmethane(DBM),2-thenoyl trifluoroacetone(TTA);neutral ligand=pyri- dine(Py),α,α'-dipyridyl(Dipy),phenanthroline(Phen)are studied and their intensities are given through dynamic coupling *** results are in agreement with those observed and caleulated using Judd-Ofelt *** may be seen that the dynamic coupling mechanism provides major contribution to the intensity of hypersensitive *** the other hand,in order to get the intensity of ~4I_(9/2)→~4G_(5/2) transition,the absorption spectra in 560—610 nm have been decomposed into threo peaks by nonlinear fitting with Lorentzian and Gaussian funetion and the“pure”intensities of hypersensitive transitions have been obtained, which are agreeable to those computed by Judd-Ofelt method and dynamic coupling model.

关键词： Studies on hypersensitive transitions of Nd in Nd