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Secure beamforming and deployment design for rate-splitting multiple access-based UAV communications

Science China(Information Sciences) 2025年第1期68卷 342-356页

作者： Bing WANG Xiaofeng tao Shujun han Huici WU Kai YANG Zhu han National Engineering Research Center of Mobile Network Technologies Beijing University of Posts and Telecommunications Peng Cheng Laboratory Department of Electrical and Computer Engineering University of Houston

Rate-splitting multiple access(RSMA) has recently gained attention as a potential robust multiple access(MA)scheme for upcoming wireless networks. Given its ability to efficiently utilize wireless resources and design interference management strategies, it can be applied to unmanned aerial vehicle(UAV) networks to provide convenient services for large-scale access ground users. However, due to the line-of-sight(LoS) broadcast nature of UAV transmission, information is susceptible to eavesdropping in RSMA-based UAV networks. Moreover, the superposition of signals at the receiver in such networks becomes complicated. To cope with the challenge, we propose a two-user multi-input single-output(MISO) RSMA-based UAV secure transmission framework in downlink communication networks. In a passive eavesdropping scenario, our goal is to maximize the sum secrecy rate by optimizing the transmit beamforming and deployment location of the UAV-base station(UAV-BS),while considering quality-of-service(QoS) constraints, maximum transmit power, and flight space limitations. To address the non-convexity of the proposed problem, the optimization problem is first decoupled into two subproblems. Then, the successive convex approximation(SCA) method is employed to solve each subproblem using different propositions. In addition, an alternating optimization(AO)-based location RSMA(L-RSMA) beamforming algorithm is developed to implement joint optimization to obtain the suboptimal solution. Numerical results demonstrate that(1) the proposed L-RSMA scheme yields a28.97% higher sum secrecy rate than the baseline L-space division multiple access(SDMA) scheme;(2) the proposed L-RSMA scheme improves the security performance by 42.61% compared to the L-non-orthogonal multiple access(NOMA) scheme.

关键词： rate-splitting multiple access UAV communication precoding optimization deployment location physical layer security

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Hybrid surgery for symptomatic chronic near-total or total occlusion of the internal carotid artery

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Chinese Medical Journal 2021年第9期134卷 1104-1106页

作者： Chang-Ming Wang jin-tao han Zi-Chang Jia Guang-Xin Yang Xuan Li Department of Vascular Surgery and Interventional Radiology Peking University Third HospitalBeijing 100191China

Stroke is the second leading cause of death globally and accounts for an estimated 5.5 million deaths each year worldwide.[1]Revascularization of the carotid artery is one of the key procedures to reduce the incidence of *** total occlusion(TO)and near-total occlusion(NO)of the carotid artery are *** for TO and NO is controversial with potential complications,including periprocedural stroke,intracranial hemorrhage,and carotid-cavernous fistula(CCF).[2]There have been attempts to implement carotid artery endarterectomy(CEA)and endovascular treatment,but the success rates were far from *** patients with TO,the success rate of revascularization is around 40%and 60%,respectively,for CEA and endovascular technique.[3]For patients with NO,the morbidity and mortality rates are 3%and 9%,respectively.

关键词： carotid occlusion artery

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非甲状腺相关性免疫眼病突眼的MRI诊断价值

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中华放射学杂志 2012年第1期46卷 28-31页

作者：金涵弢陶晓峰上海第二军医大学附属长征医院影像科 200003

目的分析非甲状腺相关性免疫眼病突眼的MRI表现和诊断价值。方法经手术病理证实的168例非甲状腺相关性免疫眼病突眼患者均行MR检查，采用头颅8通道相控阵线圈，其中3例仅平扫，165例行增强检查。结果168例中血管瘤68例，淋巴瘤34例，泪... 详细信息

目的分析非甲状腺相关性免疫眼病突眼的MRI表现和诊断价值。方法经手术病理证实的168例非甲状腺相关性免疫眼病突眼患者均行MR检查，采用头颅8通道相控阵线圈，其中3例仅平扫，165例行增强检查。结果168例中血管瘤68例，淋巴瘤34例，泪腺混合瘤14例，炎症、炎性假瘤及肉芽肿性病变12例，泪腺腺样囊腺癌6例，眼眶内神经鞘瘤6例，皮样或表皮样囊肿5例，脑膜瘤5例，孤立性纤维瘤3例，视神经胶质瘤2例，胚胎性横纹肌肉瘤2例，脂肪瘤2例，神经纤维瘤、脊索瘤、泪腺癌肉瘤、血管周细胞瘤、间叶软骨肉瘤、血管肉瘤、成熟型囊性畸胎瘤、血肿、低度恶性丛状纤维组织细胞瘤各1例。165例行增强检查者影像诊断与手术病理结果符合者111例（67．3％），包括血管瘤65例，淋巴瘤22例，泪腺混合瘤10例，炎性假瘤5例，脑膜瘤3例，泪腺腺样囊腺癌3例，视神经胶质瘤1例，神经鞘瘤1例，皮样囊肿1例。11例同时行动态增强检查，其中10例影像诊断与病理结果相符，包括血管瘤7例，淋巴瘤2例，脑膜瘤1例，其动态增强曲线分别表现为持续上升型、快进快出型和平台型、快进快出型。3例仅行MR平扫，表现为软组织肿块。结论常规眼眶MRI可以显示引起突眼的病变，对病灶的定位、定性有很大帮助，增强或动态增强扫描能进一步观察病灶血供情况。

关键词：突眼磁共振成像

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FK506 contributes to peripheral nerve regeneration by inhibiting neuroinflammatory responses and promoting neuron survival

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Neural Regeneration Research 2025年第7期20卷 2108-2115页

作者： Yuhui Kou Zongxue jin Yusong Yuan Bo Ma Wenyong Xie Na han Department of Trauma and Orthopedics Peking University People’s HospitalBeijingChina National Center for Trauma Medicine Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration(Peking University) Ministry of EducationBeijingChina Trauma Medicine Center Peking University People’s HospitalBeijingChina Department of Orthopedics China-Japan Friendship HospitalBeijingChina

FK506(Tacrolimus)is a systemic immunosuppressant approved by the *** and Drug ***506 has been shown to promote peripheral nerve regeneration,however,its precise mechanism of action and its pathways remain *** this study,we established a rat model of sciatic nerve injury and found that FK506 improved the morphology of the injured sciatic nerve,increased the numbers of motor and sensory neurons,reduced inflammatory responses,markedly improved the conduction function of the injured nerve,and promoted motor function *** findings suggest that FK506 promotes peripheral nerve structure recovery and functional regeneration by reducing the intensity of inflammation after neuronal injury and increasing the number of surviving neurons.

关键词： FK506 inflammation motor neurons nerve regeneration neuron peripheral nerve injury sensory neurons

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High-precision tip positioning composite feedforward control of linear colocated motion systems with Bi-Loop iterative feedforward tuning

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Science China Technological Sciences 2025年

作者： Junyu HU Yourui tao Shanhu LI Xu han College of Mechanical and Vehicle Engineering Hunan University State Key Laboratory of Reliability and Intelligence of Electrical Equipment Hebei University of Technology

To enhance the tip positioning accuracy and robustness against disturbances of linear colocated motion systems, a novel composite feedforward (COMFF) control with Bi-Loop iterative feedforward tuning (IFFT) is proposed. The tip positioning error consists of the coupled tip residual vibration and linear motor tracking error. Given the influence of nonlinear friction and load flexibility, the topology of COMFF is designed as decoupled structures so that COMFF can suppress the tip residual vibration and compensate for the linear motor tracking error compatibly. Furthermore, Bi-Loop IFFT is built to improve the robustness of COMFF in high-precision motor tracking performance. In the state space of the linear motor tracking error based on the projection theorem, two loops are performed in parallel along the iteration direction. One is the P-type iteration loop that drives linear motor tracking errors to converge to the zero state. The other is the observation loop constructed by the recursive least square with forgetting factors to accelerate the P-type iteration loop. Driven by the P-type iteration loop with the aid of the observation loop, the proposed COMFF is integrated with fast convergence and high robustness when confronted with model disturbances. The effectiveness of the proposed COMFF combined with Bi-Loop IFFT is validated by experiments.

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Trinuclear gold-catalyzed site-selective alkylation of peptides

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Science China Chemistry 2025年第1期68卷 249-256页

作者： Qing-Yun Fang Chengyihan Gu Yinghan Chen Wencheng Yan Yong Liang Weipeng Li Chengjian Zhu Jie han jin Xie State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Chemistry and Biomedicine Innovation Center (Chem BIC) School of Chemistry and Chemical Engineering Nanjing University Green Catalysis Center College of Chemistry Zhengzhou University State Key Laboratory of Natural Medicines China Pharmaceutical University

Selective modification of peptides has always been a challenging issue. The selective alkylation of peptides can alter the biological activity and physical properties of molecules, and it has gained significant research interest. We herein disclose an intriguing gold-catalyzed alkylation of peptides using bench-stable unactivated alkyl bromides under photoredox catalysis. A wide range of structurally diverse primary, secondary and tertiary alkyl bromides serve as effective coupling partners to precisely connect with the α-C(sp3)–H in glycine residue of peptides. This protocol demonstrates an exceptionally broad scope for alkyl halides and excellent tolerance for a wide range of useful functional groups. A series of relay transformations to construct cyclic peptides, to proceed click reaction and to realize peptide fluorescence labeling further enhance its synthetic practicality. In addition, mechanistic studies and density functional theory(DFT) calculations reveal an inner-sphere and subsequent outersphere single electron transfer(SET) mechanism.

关键词： gold catalysis peptide alkylation C-C coupling radical

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AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis

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Neural Regeneration Research 2025年第8期20卷 2408-2419页

作者： Ruiqi Qiu Mingzhu Yang Xiuxiu jin jingyang Liu Weiping Wang Xiaoli Zhang jinfeng han Bo Lei Henan Eye Hospital Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Eye Institute Henan Academy of Innovations in Medical ScienceZhengzhouHenan ProvinceChina Branch of National Clinical Research Center for Ocular Disease Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Academy of Medical Science Zhengzhou UniversityZhengzhouHenan ProvinceChina

Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell ***,there is no effective treatment for retinitis pigmentosa caused by PDE6B ***-associated virus(AAV)-mediated gene therapy is a promising strategy for treating retinitis *** aim of this study was to explore the molecular mechanisms by which AAV2-PDE6B rescues retinal *** do this,we injected retinal degeneration 10(rd10)mice subretinally with AAV2-PDE6B and assessed the therapeutic effects on retinal function and structure using dark-and light-adapted electroretinogram,optical coherence tomography,and ***-independent acquisition-mass spectrometry-based proteomic analysis was conducted to investigate protein expression levels and pathway enrichment,and the results from this analysis were verified by real-time polymerase chain reaction and western ***2-PDE6B injection significantly upregulated PDE6βexpression,preserved electroretinogram responses,and preserved outer nuclear layer thickness in rd10 *** expressed proteins between wild-type and rd10 mice were closely related to visual perception,and treating rd10 mice with AAV2-PDE6B restored differentially expressed protein expression to levels similar to those seen in wild-type *** Encyclopedia of Genes and Genome analysis showed that the differentially expressed proteins whose expression was most significantly altered by AAV2-PDE6B injection were enriched in phototransduction ***,the phototransductionrelated proteins Pde6α,Rom1,Rho,Aldh1a1,and Rbp1 exhibited opposite expression patterns in rd10 mice with or without AAV2-PDE6B ***,Bax/Bcl-2,p-ERK/ERK,and p-c-Fos/c-Fos expression levels decreased in rd10 mice following AAV2-PDE6B *** data suggest that AAV2-PDE6B-mediated gene therapy promotes phototransduction and inhibits apoptosis by inhibiting the ERK signaling pathway and upr

关键词： apoptosis AAV2-PDE6B ERK1/2 gene therapy phototransduction proteomics rd10 retinitis pigmentosa

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肾嫌色细胞癌的影像学诊断

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放射学实践 2009年第6期24卷 646-650页

作者：金涵弢陈克敏上海交通大学医学院附属瑞金医院上海200025

目的:探讨肾嫌色细胞癌(CRCC)的影像学表现特征,提高术前诊断水平。方法:回顾性分析15例CRCC病例,其中14例经B超检查;8例行CT检查,包括平扫、皮质期和实质期动态增强扫描;3例行MR检查,包括平扫T1WI、T2WI及皮质期和实质期动态增强T1WI等... 详细信息

目的:探讨肾嫌色细胞癌(CRCC)的影像学表现特征,提高术前诊断水平。方法:回顾性分析15例CRCC病例,其中14例经B超检查;8例行CT检查,包括平扫、皮质期和实质期动态增强扫描;3例行MR检查,包括平扫T1WI、T2WI及皮质期和实质期动态增强T1WI等。9例中有2例患者同时行CT和MR检查,有6例只有IVU和/或超声影像学资料。结果:病灶位于左肾11例,右肾4例,最大径2～14cm,平均5.8cm。8例CT检查中,7例病灶平扫呈等密度或以等密度为主,1例呈稍低密度为主的混杂密度团块。增强皮质期,8个病灶的强化程度均高于髓质,但低于皮质;实质期,8个病灶密度均明显低于肾实质。MR检查的3例相对于髓质,病灶在平扫T1WI上呈等信号,在T2WI上表现为低信号。病灶的强化方式与CT相似。结论:CRCC在CT、MRI上肿瘤实质大多表现为均质性,强化具有一定的特征,病灶呈类圆形或分叶状,其边缘较光整、分界清、病灶中央可出现星型瘢痕或纤维间隔等,对诊断具有较大的帮助。

关键词：癌,肾细胞体层摄影术,X线计算机磁共振成像超声检查,多普勒,彩色

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Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu Xiaoling Liu Biao Meng tao Chen Yu han Jun Wang Shibo Xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Activation energy

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腹胰发育相关胰腺、十二指肠变异

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肝胆胰外科杂志 2010年第5期22卷 380-383页

作者：金涵弢王俭第二军医大学附属长征医院影像科上海200003

目的从腹胰发育角度解释胰腺、十二指肠降段变异的影像特点。方法从过去5年间本院CT、MRI资料中遴选腹胰变异病例,从腹胰发育角度解释这些变异的形成机制。结果 (1)胰腺变异:①异位胰腺(n=1):罕见,其胰管通向十二指肠乳头;②环状胰腺(n=... 详细信息

目的从腹胰发育角度解释胰腺、十二指肠降段变异的影像特点。方法从过去5年间本院CT、MRI资料中遴选腹胰变异病例,从腹胰发育角度解释这些变异的形成机制。结果 (1)胰腺变异:①异位胰腺(n=1):罕见,其胰管通向十二指肠乳头;②环状胰腺(n=2)/半环状胰腺(n=2):少见,十二指肠前方软组织密度肿块,各扫描像上,其结构、密度与正常胰腺相仿;③胰腺异常突起(n=22):常见,可与胰腺相连或有脂肪间隙相隔;④胰腺分裂(n=23):常见,常有不均匀脂肪沉积或胰头内胰管局限性扩张;⑤腹胰发育不良(n=3)和腹胰缺如(n=2):罕见,胰头可增大,钩突不明显者呈球形胰头。(2)十二指肠相关变异:①十二指肠憩室(n=48):常见,胰管、胆总管常开口在憩室内;②十二指肠狭窄(n=4):见于环状胰腺。结论腹胰发育异常可导致胰腺、十二指肠多种形态异常,某些异常易发生炎症,某些异常误为肿瘤,应提高对这些变异的认识。

关键词：胰腺腹胰解剖变异诊断

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