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球拍形切口乳房成形术治疗乳腺癌患者的临床效果

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临床医学研究与实践 2020年第11期5卷 71-72页

作者：靳立龙山东省夏津县人民医院山东德州253200

目的探讨球拍形切口乳房成形术治疗乳腺癌患者的临床效果。方法选取2015年1月至2017年1月我院收治的82例乳腺癌患者,采用随机数字表法将其分为对照组(41例,常规保乳手术)和研究组(41例,球拍形切口乳房成形术)。比较两组患者的治疗效果... 详细信息

目的探讨球拍形切口乳房成形术治疗乳腺癌患者的临床效果。方法选取2015年1月至2017年1月我院收治的82例乳腺癌患者,采用随机数字表法将其分为对照组(41例,常规保乳手术)和研究组(41例,球拍形切口乳房成形术)。比较两组患者的治疗效果、乳房美观情况、并发症发生情况及复发率。结果研究组的治疗总有效率明显高于对照组(P<0.05)。研究组乳头纵向偏移距离、乳头横向偏移距离、瘢痕、凹陷程度、对称性评分及总分均高于对照组(P<0.05)。研究组并发症总发生率及复发率均低于对照组(P<0.05)。结论球拍形切口乳房成形术治疗乳腺癌的临床效果显著,值得临床推广应用。

关键词：球拍形切口乳房成形术乳腺癌整形保乳手术美观程度

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有限元软件结构分析模块的并行开发及应用

上海交通大学学报 2004年第8期38卷 1354-1357页

作者：李丽君金先龙李渊印李根国上海交通大学高性能计算中心上海200030 上海超级计算中心上海200030

通过有限元分析软件结构分析模块在"神威 "超级计算机上的并行化二次开发,把商用有限元软件强大的前后处理能力与超级计算机的高性能计算能力结合起来,扩大了分析规模,提高了分析速度.算例分析验证了该研究的正确性和高效性,为大型工程... 详细信息

通过有限元分析软件结构分析模块在"神威 "超级计算机上的并行化二次开发,把商用有限元软件强大的前后处理能力与超级计算机的高性能计算能力结合起来,扩大了分析规模,提高了分析速度.算例分析验证了该研究的正确性和高效性,为大型工程计算提供了强有力的工具.

关键词：有限元软件结构分析并行计算

Endoplasmic reticulum stress and autophagy in cerebral ischemia/reperfusion injury:PERK as a potential target for intervention

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Neural Regeneration Research 2025年第5期20卷 1455-1466页

作者： Ju Zheng Yixin li Ting Zhang Yanlin Fu Peiyan long Xiao Gao Zhengwei Wang Zhizhong Guan Xiaolan Qi Wei Hong Yan Xiao Key Laboratory of Endemic and Ethnic Diseases Ministry of Education&Key Laboratory of Medical Molecular Biology of Guizhou ProvinceGuizhou Medical UniversityGuiyangGuizhou ProvinceChina Guizhou Center for Disease Control and Prevention GuiyangGuizhou ProvinceChina Department of Histology and Embryology Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry GuiyangGuizhou ProvinceChina

Several studies have shown that activation of unfolded protein response and endoplasmic reticulum(ER)stress plays a crucial role in severe cerebral ischemia/reperfusion *** occurs within hours after cerebral ischemia,but the relationship between ER stress and autophagy remains *** this study,we established experimental models using oxygen-glucose deprivation/reoxygenation in PC12 cells and primary neurons to simulate cerebral ischemia/reperfusion *** found that prolongation of oxygen-glucose deprivation activated the ER stress pathway protein kinase-like endoplasmic reticulum kinase(PERK)/eukaryotic translation initiation factor 2 subunit alpha(e IF2α)-activating transcription factor 4(ATF4)-C/EBP homologous protein(CHOP),increased neuronal apoptosis,and induced ***,inhibition of ER stress using inhibitors or by si RNA knockdown of the PERK gene significantly attenuated excessive autophagy and neuronal apoptosis,indicating an interaction between autophagy and ER stress and suggesting PERK as an essential target for regulating *** autophagy with chloroquine exacerbated ER stress-induced apoptosis,indicating that normal levels of autophagy play a protective role in neuronal injury following cerebral ischemia/reperfusion *** from this study indicate that cerebral ischemia/reperfusion injury can trigger neuronal ER stress and promote autophagy,and suggest that PERK is a possible target for inhibiting excessive autophagy in cerebral ischemia/reperfusion injury.

关键词： apoptosis ATF4 autophagy C/EBP homologous protein cerebral ischemia/reperfusion injury eIF2α endoplasmic reticulum stress PERK

Substrate bias effects in p-channel GaN-on-Si transistors

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Science China(Information Sciences) 2025年第1期68卷 404-405页

作者： Mengyao ZHAO Jie MA Lanlan YANG Chuanqi PAN Denggui WANG Jianjun ZHOU Sheng li Jiaxing WEI long ZHANG Siyang liU Weifeng SUN National ASIC System Engineering Research Center School of Integrated Circuits Southeast University National Center of Technology Innovation for Electronic Design Automation Southeast University National Key Laboratory of Solid-State Microwave Devices and Circuits

The drain current （ID） of the n-channel GaN field-effecttransistor （n-FET） is influenced by the substrate-to-source bias voltage (VBS)（substrate bias effect）[1].Actually,nonzero VBSis also likely to occur in p-FET in real application,because the source electrode of p-FET is usually connected to high *** study reports the dependency between IDand VBSin p-FET for the first time,and analyzes the underlying mechanisms from the perspective of vertical electric field （EF） distribution.

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Broadband low-frequency sound absorption of multifunctional composite metastructure

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Science China Technological Sciences 2025年

作者： Yilong YANG Shanshan liU Yan li Tong GAO Yongdong PAN Yong li Yabin jin School of Aerospace Engineering and Applied Mechanics Tongji University Institute of Acoustics School of Physics Science and Engineering Tongji University Shanghai Institute of Aircraft Mechanics and Control State International Joint Research Center of Aerospace Design and Additive Manufacturing Northwestern Polytechnical University Shanghai Key Laboratory of Intelligent Sensing and Detection Technology School of Mechanical and Power Engineering East China University of Science and Technology

In this study, we fabricated multifunctional metastructures from carbon fiber-reinforced plastic composites using additive manufacturing technology. These metastructures are characterized by their lightweight, load-bearing capacity, and broadband low-frequency sound absorption properties. The metastructure consists of 36 unit cells, and non-local coupling mechanism was considered for designing the sound absorption performance. We developed an acoustic impedance theory tailored for the metastructure, facilitating an analysis of thermal and viscous dissipation mechanisms. It is proven theoretically and experimentally that the proposed composite metastructure can achieve a noise reduction with an average sound absorption coefficient greater than 0.9 across frequencies in the rage of 330–1500 Hz. We also studied the metastructure’s quasi-static and cyclic compression performance, confirming its efficient absorption capabilities after cyclic compression. The proposed design and additive manufacturing method for composite metastructures provides a novel pathway for creating lightweight, multifunctional structures with diverse applications, such as aerospace engineering.

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双内齿矩形迷宫流道灌水器水力特性分析

太原理工大学学报 2016年第6期47卷 774-778页

作者：金龙李治勤马炎超王超太原理工大学水利科学与工程学院太原030024

在目前常用的矩形迷宫流道灌水器中加入内齿,形成双内齿矩形迷宫流道灌水器;利用流体力学软件CFD对增加内齿前、后两种类型的灌水器进行数值模拟分析,比较了两种类型灌水器的水力性能,并且研究不同内齿高度和内齿间距对双内齿矩形迷宫... 详细信息

在目前常用的矩形迷宫流道灌水器中加入内齿,形成双内齿矩形迷宫流道灌水器;利用流体力学软件CFD对增加内齿前、后两种类型的灌水器进行数值模拟分析,比较了两种类型灌水器的水力性能,并且研究不同内齿高度和内齿间距对双内齿矩形迷宫流道灌水器水力性能的影响。结果表明:增加内齿后形成的双内齿矩形迷宫流道灌水器的流态指数普遍比目前常用矩形迷宫流道灌水器的流态指数小,水力性能较好。流量系数随着内齿高度的增大而减小,内齿间距对流量系数的影响不大。流态指数随着内齿高度的增加呈先减小后增大的趋势,当内齿高度分别为0.3mm和1.1mm时,内齿间距对流态指数的影响不大;当内齿高度分别为0.3,0.5,0.7mm时,流态指数随着内齿间距的增加而增大;当内齿高度为0.7mm,内齿间距为0.3mm时,流态指数达到最小。

关键词：迷宫流道内齿数值模拟水力性能灌水器

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大学生体质健康状况发展变化规律的研究

西安体育学院学报 2003年第5期20卷 42-43页

作者：魏锦龙马莉李世荣延安大学体育学院陕西延安716000

采用文献研究法、调查研究法和数理统计法等,对延安大学98年入校的本科学生的身体形态、机能、身体素质进行了4年追踪研究,得出延安大学学生在校期间体质健康状况发展变化的特点、规律、趋势及存在的差异和原因,并针对存在的问题提出了... 详细信息

采用文献研究法、调查研究法和数理统计法等,对延安大学98年入校的本科学生的身体形态、机能、身体素质进行了4年追踪研究,得出延安大学学生在校期间体质健康状况发展变化的特点、规律、趋势及存在的差异和原因,并针对存在的问题提出了改进措施与建议。

关键词：大学生体质健康

钒团簇的几何和电子结构——从分子到体相性质的演化

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物理学报 2001年第10期50卷 1907-1913页

作者：丁长庚杨金龙李群祥中国科学技术大学选键化学开放实验室合肥230026

基于密度泛函理论 ,优化了钒团簇Vn(n =2— 9,13 ,15 ,19,2 7,5 1)的几何结构 ,通过研究键长、配位数、平均结合能、电离势、电子亲和能、总的态密度和平均磁矩随着尺寸的变化规律 ,从理论上揭示了n≤ 9的钒团簇电子结构具有分立特征的... 详细信息

基于密度泛函理论 ,优化了钒团簇Vn(n =2— 9,13 ,15 ,19,2 7,5 1)的几何结构 ,通过研究键长、配位数、平均结合能、电离势、电子亲和能、总的态密度和平均磁矩随着尺寸的变化规律 ,从理论上揭示了n≤ 9的钒团簇电子结构具有分立特征的分子行为和很强的尺寸效应 ,13≤n≤ 19是从分子向体相态结构变化的过渡区域 ;V2 7和V51 的态密度已趋向于体相的三峰结构。

关键词：体相性质演化钒团簇密度泛涵理论电子结构几何结构磁性分子

Corrosion and wear behaviors of PVD CrN and CrSiN coatings in seawater

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Transactions of Nonferrous Metals Society of China 2016年第1期26卷 175-184页

作者：单磊章杨荣王永欣李金龙蒋欣陈建敏中国科学院宁波材料技术与工程研究所中国科学院海洋新材料与应用技术重点实验室宁波315201 中国科学院宁波材料技术与工程研究所浙江省海洋材料与防护技术重点实验室宁波315201 浙江纺织服装职业学院机电分院宁波315211

To improve the tribological performance of 316 L in seawater, the CrN and CrSiN coatings were deposited by multi-arc ion plating. The coatings were systematically characterized. Corrosion properties were evaluated by immersion test and anodic polarization measurement. The friction and wear properties of the CrN and CrSiN coatings were investigated by ball-on-disk tribometer in artificial seawater. The results show that the CrN coating has strong（111） and（200） preferred orientations and the intensity of the peaks decreases for the CrSiN coating. The hardness of the CrSiN coating is higher than that of the CrN coating. The CrSiN coating presents better corrosion resistance in seawater. The friction coefficient and wear rate of the CrSiN coating are lower than those of the CrN coating, indicating positive effect of Si addition on tribological performance in seawater. The coatings could significantly improve the wear resistance of the 316 L in seawater.

关键词： CrSiN coating wear corrosion seawater