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Organic interfacial engineering of gold nanowires for selective glycerol electrooxidation

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Chinese Chemical Letters 2024年第3期35卷 502-507页

作者： Zhe Wang Qingling Hong Boqiang Miao Tianjiao Wang Yu Ding Pujun jin Pei chen Yu chen Key Laboratory of Macromolecular Science of Shaanxi Province Key Laboratory of Applied Surface and Colloid Chemistry(Ministry of Education)Shaanxi Key Laboratory for Advanced Energy DevicesSchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an 710062China

The selective electrochemical conversion of glycerol into value-added products is a green and sustainable strategy for the biomass *** this work,Au nanowires(Au-NW)modified with polyethyleneimine(PEI)molecule(Au-NW@PEI)is obtained by an up-bottom post-modification *** characterization,molecular dynamics simulation and density functional theory demonstrate that the loose-packed PEI monolayer firmly and uniformly distribute on the Au-NW surface due to the strong Au-N *** experiments and product analysis display that PEI modification significantly enhance the electro-activity of Au-NW for the glycerol electro-oxidation reaction(GEOR)due to the electronic ***,the steric hindrance and electrostatic effect of PEI layer make the optimizing adsorption of intermediates ***,the selectivity of C3 product glyceric acid over Au-NW@PEI is increased by nearly 20%.The work thus indicates that the rational design of metal-organic interface can effectively elevate the electro-activity and selectivity of Au nanostructures,which may have wide application in biomass development.

关键词： Glycerol electrooxidation reaction Organic interface engineering Gold-based nanomaterials Electrocatalysis Selectivity

PPP1R14A is Associated with Immunotherapy Resistance in Head and Neck Squamous Cell Carcinoma Identified by Single-Cell and Bulk RNA-Sequencing

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Chinese Medical Sciences Journal 2024年第2期39卷 111-121页

作者： jun-Jie Ma Lei Zhang jin Lu Hao-Xuan Zhang Department of Clinical Medicine Bengbu Medical UniversityBengbu 233030AnhuiChina Department of General Surgery The Second Affiliated Hospital of Bengbu Medical UniversityBengbu 233030AnhuiChina Department of Human Anatomy Bengbu Medical UniversityBengbu 233030AnhuiChina Anhui Key Laboratory of Computational Medicine and Intelligent Health Bengbu Medical UniversityBengbu 233030AnhuiChina

Objective To identify nivolumab resistance-related genes in patients with head and neck squamous cell carcinoma(HNSCC)using single-cell and bulk RNA-sequencing *** The single-cell and bulk RNA-sequencing data downloaded from the Gene Expression Omnibus database were analyzed to screen out differentially expressed genes(DEGs)between nivolumab resistant and nivolumab sensitive patients using R *** Least Absolute Shrinkage Selection Operator(LASSO)regression and Recursive Feature Elimination(RFE)algorithm were performed to identify key genes associated with nivolumab *** enrichment of DEGs was analyzed with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes *** relationships of key genes with immune cell infiltration,differentation trajectory,dynamic gene expression profiles,and ligand-receptor interaction were *** We found 83 *** were mainly enriched in T-cell differentiation,PD-1 and PD-L1 checkpoint,and T-cell receptor *** six key genes identified using machine learning algorithms,only PPP1R14A gene was differentially expressed between the nivolumab resistant and nivolumab sensitive groups both before and after immunotherapy(P0,P<0.05),lower differentiation of infiltrated immune cells(P<0.05),and a higher degree of interaction between HLA and CD4(P<0.05).Conclusions PPP1R14A gene is closely associated with resistance to nivolumab in HNSCC ***,PPP1R14A may be a target to ameliorate nivolumab resistance of HNSCC patients.

关键词： PPP1R14A head and neck squamous cell carcinoma immunotherapy drug resistance

Characteristics and suppression of beam distortion in a high repetition rate nanosecond stimulated Brillouin scattering phase conjugation mirror

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High Power Laser Science and Engineering 2024年第2期12卷 69-78页

作者： Yifu chen Bowen Tan Duo jin Bin chen Zhenxu Bai Kun Wang Yulei Wang Zhiwei Lü School of Astronautics Harbin Institute of TechnologyHarbinChina Center for Advanced Laser Technology Hebei University of TechnologyTianjinChina Hebei Key Laboratory of Advanced Laser Technology and Equipment TianjinChina School of Energy and Environmental Engineering Hebei University of TechnologyTianjinChina

The stimulated Brillouin scattering phase conjugation mirror (SBS-PCM) based on liquid media is widely used in high-power laser systems due to its robust thermal load capacity, high energy conversion efficiency and improved beam quality. Nevertheless, with an increase in the pump repetition rate, thermally-induced blooming and optical breakdown can emerge, leading to distortions in the Stokes beam. In this study, we delved into the thermal effects in liquid SBS-PCMs employing hydrodynamic analysis, establishing a relationship between beam profile distortion and the thermal convection field. We calculated the temperature and convection velocity distribution based on the pump light parameters and recorded the corresponding beam profiles. The intensities of the beam profiles were modulated in alignment with the convection directions, reaching a velocity peak of 2.85 mm/s at a pump pulse repetition rate of 250 Hz. The residual sum of squares (RSS) was employed to quantify the extent of beam profile distortion relative to a Gaussian distribution. The RSS escalated to 7.8, in contrast to 0.7 of the pump light at a pump pulse repetition rate of 500 Hz. By suppressing thermal convection using a high-viscosity medium, we effectively mitigated beam distortion. The RSS was reduced to 0.7 at a pump pulse repetition rate of 500 Hz, coinciding with a twentyfold increase in viscosity, thereby enhancing the beam quality. By integrating hydrodynamic analysis, we elucidated and mitigated distortion with targeted solutions. Our research offers an interdisciplinary perspective on studying thermal effects and contributes to the application of SBS-PCMs in high-repetition-rate laser systems by unveiling the mechanism of photothermal effects.

关键词： beam profile high power high repetition rate stimulated Brillouin scattering phase conjugation mirror thermal convection

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Characteristics and origin of low-organicmatter carbonate source rocks in the Middle-Upper Ordovician, Tarim Basin, northwestern China

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Journal of Palaeogeography 2024年第3期13卷 594-619页

作者： jun-Qing chen Fu-Jie Jiang Xiong-Qi Pang Hai-jun Yang Kan-Yuan Shi Bo Pang Hong Pang Jian-Fa chen Zhuo-Heng chen Xin-Gang Zhang Song Wu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing 102249China Basic Research Center for Energy Interdisciplinary College of ScienceChina University of Petroleum(Beijing)Beijing 102249China Beijing Key Laboratory of Optical Detection Technology for Oil and Gas China University of Petroleum(Beijing)Beijing 102249China College of Geosciences China University of Petroleum(Beijing)Beijing 102249China Research Institute of Petroleum Exploration and Development PetroChina Tarim Oilfield CompanyKorla 841000Xinjiang Uygur Autonomous RegionChina Geological Survey of Canada Natural Resources CanadaCalgary T2L 2A7Canada

The continually-discovered large volumes of marine hydrocarbons indicate a huge exploration potential within the carbonate rocks of Ordovician in the Tarim Basin,northwestern *** Middle-Upper Ordovician(O2+3)carbonate source rocks are at a highly mature *** rocks presently contain a low amount of total organic carbon(TOC_(pd)≤0.5%)(TOC_(pd) means the present-day TOC).A mass balance approach is used to identify the source rocks that have expelled *** characteristics and origin of hydrocarbon expulsion from low-TOC_(pd) source rocks are studied,which are significant for oil exploration in the *** results showed that a low-TOC_(pd) O2+3 source rock having expelled hydrocarbons was type I and had a very narrow oil *** a high rock maturity and a high original TOC(TOCo)value exceeding 1%,nearly 80%of the generated hydrocarbons were *** content of gammacerane and C28 steranes in the oil and source rock extracts were relatively lean,with a V-shaped distribution of regular steranes,suggesting a possible genetic relation between the low-TOC_(pd) source rocks and the marine oil in the Tabei *** planktonic algae or acritarchs were the main hydrocarbon parent materials,distributed in the subsiding platform-slope *** matter was preserved under reducing conditions,and source rocks were formed with a favorable kerogen type and a moderate hydrocarbon generation *** study illustrates the hydrocarbon expulsion of low TOC_(pd) source rocks in northern Tarim Basin,which is greatly significant for analyzing the genesis of marine crude oil in Tarim Basin,and evaluating the distribution of marine source *** research method is theoretically significant for oil and gas exploration in the same type of highlymature carbonate paleobasins.

关键词： Carbonate source rock Mass balance approach Present-day TOC Genesis mechanism Tarim Basin

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Intramolecular Hydrogen Bond Improved Durability and Kinetics for Zinc‑Organic Batteries

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Nano-Micro Letters 2024年第3期16卷 138-148页

作者： Tianjiang Sun jun Pan Weijia Zhang Xiaodi Jiang Min cheng Zhengtai Zha Hong jin Fan Zhanliang Tao Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Renewable Energy Conversion and Storage CenterCollege of ChemistryNankai UniversityHaihe Laboratory of Sustainable Chemical TransformationsTianjin 300071People’s Republic of China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology School of Physics Science and EngineeringTongji UniversityShanghai 200092People’s Republic of China

Organic compounds have the advantages of green sustainability and high designability,but their high solubility leads to poor durability of zinc-organic ***,a high-performance quinone-based polymer(H-PNADBQ)material is designed by introducing an intramolecular hydrogen bonding(HB)*** intramolecular HB(C=O⋯N-H)is formed in the reaction of 1,4-benzoquinone and 1,5-naphthalene diamine,which efficiently reduces the H-PNADBQ solubility and enhances its charge transfer in *** situ ultraviolet-visible analysis further reveals the insolubility of H-PNADBQ during the electrochemical cycles,enabling high durability at different current ***,the H-PNADBQ electrode with high loading(10 mg cm^(-2))performs a long cycling life at 125 mA g^(-1)(>290 cycles).The H-PNADBQ also shows high rate capability(137.1 mAh g^(−1)at 25 A g^(−1))due to significantly improved kinetics inducted by intramolecular *** work provides an efficient approach toward insoluble organic electrode materials.

关键词： Zn-organic batteries H-PNADBQ polymer Intramolecular hydrogen bond Reduced solubility Improvedπ-conjugated level

An adaptive physics-informed deep learning method for pore pressure prediction using seismic data

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Petroleum Science 2024年第2期21卷 885-902页

作者： Xin Zhang Yun-Hu Lu Yan jin Mian chen Bo Zhou State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Petroleum Engineering China University of Petroleum(Beijing)Beijing102249China College of Artificial Intelligence China University of Petroleum(Beijing)Beijing102249China PetroChina Tarim Oilfield Company KorlaXinjiang841000China

Accurate prediction of formation pore pressure is essential to predict fluid flow and manage hydrocarbon production in petroleum *** deep learning technique has been receiving more interest due to the great potential to deal with pore pressure ***,most of the traditional deep learning models are less efficient to address generalization *** fill this technical gap,in this work,we developed a new adaptive physics-informed deep learning model with high generalization capability to predict pore pressure values directly from seismic ***,the new model,named CGP-NN,consists of a novel parametric features extraction approach(1DCPP),a stacked multilayer gated recurrent model(multilayer GRU),and an adaptive physics-informed loss *** machine training,the developed model can automatically select the optimal physical model to constrain the results for each pore pressure *** CGP-NN model has the best generalization when the physicsrelated metricλ=0.5.A hybrid approach combining Eaton and Bowers methods is also proposed to build machine-learnable labels for solving the problem of few *** validate the developed model and methodology,a case study on a complex reservoir in Tarim Basin was further performed to demonstrate the high accuracy on the pore pressure prediction of new wells along with the strong generalization *** adaptive physics-informed deep learning approach presented here has potential application in the prediction of pore pressures coupled with multiple genesis mechanisms using seismic data.

关键词： Pore pressure prediction Seismic data 1D convolution pyramid pooling Adaptive physics-informed loss function High generalization capability

A Stroke-Limitation AMD Control System with Variable Gain and Limited Area for High-Rise Buildings

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工程与科学中的计算机建模(英文) 2024年第1期138卷 865-884页

作者： Zuo-Hua Li Qing-Gui Wu jun Teng Chao-jun chen School of Civil and Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen518055China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong100872China

Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural *** active mass damper(AMD)with stroke limitations is often used to avoid ***,a strokelimited AMD control system with a fixed limited area shortens the available AMD stroke and leads to significant control *** solve this problem,the design approach with variable gain and limited area(VGLA)is proposed in this ***,the boundary of variable-limited areas is calculated based on the real-time status of the moving *** variable gain(VG)expression at the variable limited area is deduced by considering the saturation of AMD ***,numerical simulations of a stroke-limited AMD control system with VGLA are conducted on a high-rise building *** numerical simulations show that the proposed approach has superior strokelimitation performance compared with a stroke-limited AMD control system with a fixed limited ***,the proposed approach is validated through experiments on a four-story steel frame.

关键词： High-rise buildings active control stroke limitations variable gain variable limited area

Applications of single-cell RNA sequencing in spermatogenesis and molecular evolution

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Zoological Research 2024年第3期45卷 575-585页

作者： Wen-Bo chen Meng-Fei Zhang Fan Yang jin-Lian Hua College of Veterinary Medicine Shaanxi Centre of Stem Cells Engineering&TechnologyNorthwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China

Spermatogenic cell heterogeneity is determined by the complex process of spermatogenesis ***,effectively revealing the regulatory mechanisms underlying mammalian spermatogenic cell development and differentiation via traditional methods is *** in technology have led to the emergence of many single-cell transcriptome sequencing protocols,which have partially addressed these *** this review,we detail the principles of 10x Genomics technology and summarize the methods for downstream analysis of single-cell transcriptome sequencing ***,we explore the role of single-cell transcriptome sequencing in revealing the heterogeneity of testicular ecological niche cells,delineating the establishment and disruption of testicular immune homeostasis during human spermatogenesis,investigating abnormal spermatogenesis in humans,and,ultimately,elucidating the molecular evolution of mammalian spermatogenesis.

关键词： Single-cell RNA sequencing(scRNA-seq) Spermatogenesis Molecular evolution Sertoli cell

Insect-specific RNA virus affects the stylet penetration activity of brown citrus aphid(Aphis citricidus)to facilitate its transmission

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Insect Science 2024年第1期31卷 255-270页

作者： Xin An Qiaoying Gu jing Wang Tengyu Chang Wei Zhang jin-jun Wang jinzhi Niu Key Laboratory of Entomology and Pest Control Engineering College of Plant ProtectionAcademy of Agricultural ScienceSouthwest UniversityChongqingChina

Sap-sucking insects often transmit plant viruses but also carry insect viruses,which infect insects but not *** impact of such insect viruses on insect host biology and ecology is largely ***,we identified a novel insect-specific virus carried by brown citrus aphid(Aphis citricidus),which we tentatively named Aphis citricidus picornavirus(AcPV).Phylogenetic analysis discovered a monophyletic cluster with AcPV and other unassigned viruses,suggesting that these viruses represent a new family in order *** infection with AcPV triggered aphid antiviral immunity mediated by RNA interference,resulting in asymptomatic ***,we found that AcPV was transmitted horizontally by secretion of the salivary gland into the feeding sites of *** influenced aphid stylet behavior during feeding and increased the time required for intercellular penetration,thus promoting its transmission among aphids with plants as an intermediate *** gene expression results suggested that this mechanism was linked with transcription of salivary protein genes and plant defense hormone ***,our results show that the horizontal transmission of AcPV in brown citrus aphids evolved in a manner similar to that of the circulative transmission of plant viruses by insect vectors,thus providing a new ecological perspective on the activity of insect-specific viruses found in aphids and improving the understanding of insect virus ecology.

关键词： electrical penetration graph feeding behavior insect virus transmission Picornavirales salivary protein