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Segmentation of Salivary Gland Tumors in Ultrasonic Images Based on Anisotropic Diffusion and Random Walk

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Segmentation of Salivary Gland Tumors in Ultrasonic Images B...

Potential association of long noncoding RNA HA117 with tetralogy of Fallot

2012 IEEE 11th International Conference on Signal Processing(ICSP 2012)

作者： SU Hai-nan CHEN Hou-jin li Ju-peng li Yan-feng School of Electronic and Information Engineering Beijing Jiaotong University

ISBN: (纸本)9781467321969

Aimed at the difficult segmentation of ultrasonic tumor image with strong speckle noise, low contrast and weak boundaries, a novel method for segmentation of ultrasonic image is proposed. In order to suppress speckle noise and enhance the edge details, the anisotropic diffusion algorithm combined with the Laplacian operator is introduced into ultrasound images, of which the operator is able to discriminate the gray changes caused by noise or the edge. Then the random walk model in graph theory is employed to achieve an effective segmentation. Lots of clinical ultrasound images of salivary gland tumor are tested and the experiment results demonstrate that the proposed method possesses the nice properties of anisotropic diffusion algorithm and random walk algorithm, overcoming prone over-segmentation or under-segmentation in traditional random walk .In addition, the method bears a high calculating speed and segments tumor accurately and effectively.

关键词： ultrasonic image segmentation random walk anisotropic diffusion salivary gland tumors speckle noise

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Genes & Diseases 2018年第2期5卷 185-190页

作者： Quan Wang Zhili Wang Chun Wu Zhengxia Pan li Xiang Hang liu Xin jin Kerong Tong Shulei Fan Xianqing jin Ministry of Education Key Laboratory of Child Development and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Key Laboratory of PediatricsChongqingChina Department of Cardiothoracic Surgery Children’s Hospital of Chongqing Medical UniversityChongqingChina Renal Department and Nephrology Institute Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduChina

Tetralogy of Fallot(TOF)is a congenital heart disease characterized by abnormal cardiomyocyte differentiation in the right ventricular outflow tract(RVOT),and HA117 is a novel long noncoding RNA(lncRNA)with anti-differentiation *** investigate the potential association of HA117 with TOF,we collected 84 RVOT tissues from patients with *** determined the expression of HA117 in RVOT samples from TOF patients and collected clinical data to conduct a cross-sectional and short-term follow-up *** ratio,Nakata index,and left ventricular end-diastolic volume index(LVEDVI)were negatively correlated with the expression of HA117 based on subgroup analysis,correlation analysis and logistic regression ***,cardiopulmonary bypass(CPB)time and ICU stay were longer in patients with higher expression of HA117 than in patients with lower expression of ***,percentage improvement in SPO2 was significantly reduced in patients with increased HA117 expression at 6 months after *** results suggested that the increased expression of the novel lncRNA HA117 is a risk factor for unfavorable McGoon ratio,Nakata index and LVEDVI in TOF ***,an increased expression of HA117 might lead to adverse short-term outcomes in TOF patients.

关键词： HA117 Tetralogy of Fallot Long noncoding RNA McGoon ratio Nakata index

Reduction of OsFLW7 expression enhanced leaf area and grain production in rice

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Science Bulletin 2017年第24期62卷 1631-1633页

作者： jing Xu li Wang Yue-xing Wang Da-li Zeng Meng-yu Zhou Xue Fu Wei-jun Ye Jiang Hu li Zhu De-yong Ren Zhen-yu Gao Guo-jun Dong Long-biao Guo Guang-heng Zhang Qian Qian State Key Laboratory of Rice Biology China National Rice Research Institute Hangzhou 310006 Zhejiang China

Increasing rice production is important to ensure food security in China. Exploring yield potential and identifying genes beneficial to yield are important goals in the modern rice breeding. Generally, controlling leaf morphology, increasing photosynthesis efficiency and modulating the ＂sink-source＂ relationship can pro- mote the breeding of high-yield rice as well as other cereal crops . The morphology of the leaf includes length, width and degree of curl after its emergence from the meristem and is determined by the establishment of polariW along the adaxial-abaxial, ventral-dorsal and medial-lateral axes and regulated at genetic, hormonal and environmental levels . Rice leaf morphology varies widely among rice subspecies and cultivars. Quantitative trait loci （QTLs） affecting leaf shape commonly have pleiotropic effects on rice yield , which are more useful than mutant genes for studying the molecular mechanism of leaf shape regulation and their application to rice breeding.

关键词： Reduction OsFLW7 expression enhanced leaf area grain production in rice

Combination of spark discharge and nanoparticle-enhanced laser-induced plasma spectroscopy

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Chinese Physics B 2022年第8期31卷 494-499页

作者： Qing-Xue li Dan Zhang Yuan-Fei Jiang Su-Yu li An-Min Chen Ming-Xing jin Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China

A combination of spark discharge and nanoparticle-enhanced laser-induced plasma spectroscopy is *** Au nanoparticles at the surface of a brass target can enhance the coupling of the target and the *** atoms in the brass sample are *** a secondary excitation source,spark discharge reheats the generated plasma,which further amplifies the enhancement results of *** spectral intensity with the spark discharge increases more obviously with nanoparticle concentration increasing than without the spark ***,plasma temperature and electron density are calculated by the Boltzmann plot and Stark *** changes in the plasma temperature and electron density are consistent with the spectral emission changes.

关键词： laser-induced plasma spectroscopy spark discharge nanoparticle spectral enhancement

Octopus-like DNA nanostructure coupled with graphene oxide enhanced fluorescence anisotropy for hepatitis B virus DNA detection

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Chinese Chemical Letters 2024年第6期35卷 531-535页

作者： Jia-li Xie Tian-jin Xie Yu-Jie Luo Kai Mao Cheng-Zhi Huang Yuan-Fang li Shu-Jun Zhen Key Laboratory of Luminescence Analysis and Molecular Sensing(Southwest University) Ministry of EducationCollege of Chemistry and Chemical EngineeringSouthwest UniversityChongqing 400715China Key Laboratory of Luminescent and Real-Time Analytical Chemistry(Southwest University) Chongqing Science and Technology BureauCollege of Pharmaceutical SciencesSouthwest UniversityChongqing 400715China

Fluorescence Anisotropy(FA)is an effective biochemical detection method based on molecular *** oxide(GO)has been extensively used as an FA ***,the enhancement of FA by GO alone is limited and the strong scattering of GO will easily make the measurement of FA *** order to address these problems,an octopus-like DNA nanostructure(ODN)was designed and coupled with GO to enhance the FA together in this *** mimicking the multi-clawed structure of the octopus,the ODN can be adsorbed on GO tightly,which not only could improve the sensitivity because of the double FA enhancement abilities of GO and ODN,but also could improve the specificity due to the decrease of the nonspecific interaction in complex ***,ODN could maintain a certain distance between the fluorophore and GO to reduce the fluorescence quenching efficiency of GO,which could improve the *** method has been applied for the detection of hepatitis B virus DNA(HBV-DNA)in a range of 1-50 nmol/L and the limit of detection(LOD)was 330 pmol/*** addition,the proposed method has been successfully utilized to detect HBV-DNA in human serum,indicating that this method has a great practical application prospect.

关键词： Fluorescence anisotropy Graphene oxide(GO) Octopus-like DNA nanostructure HBV-DNA

Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys

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Science China Chemistry 2016年第9期59卷 1211-1215页

作者： jin Yang Yaqi An Haiyan Wu Miao liu Weiguang Wang Xue Du Yan li Jianxin Pu Handong Sun State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650201 China University of Chinese Academy of Sciences Beijing 100049 China

Four new diterpenoids, phyllostachysins I-L （1-4）, along with a known one, hebeiabinin B （5）, were isolated from the aerial parts oflsodonphyllostachys （***）. Compounds 1 and 2 feature an ent-kaurane backbone, and 3, 4 and 5 bear an ent-abietane skeleton. Their structures were elucidated by means of spectroscopic analysis. Compounds 3 and 4 exhibited significant cytotoxic activity against human tumor cell lines （HL-60, SMMC-7721, A-549, MCF-7 and SW-480）, and strongly inhibited NO production in LPS-stimulated RAW264.7 cells.

关键词： lsodon phyllostachys diterpenoid ent-kaurane ent-abietane

High-Efficiency Quantum Routing in a Multi-Cross-Shaped Waveguide

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Chinese Physics Letters 2019年第3期36卷 32-36页

作者： jin-Song Huang jing-Wen Wang Yao Wang Yan-ling li School of Information Engineering Jiangxi University of Science and Technology

Efficiently routing the quantum signals between different channels is essential in a quantum multichannel *** investigate the quantum routing in a multi-cross-shaped waveguide coupled to driven three-level *** results show that the high routing capacity transferring from the input channel to the other channels can be explicitly enhanced by effective reflection potentials. The proposed system may be utilized as a scalable quantum device to control single-photon routing.

关键词： CCA High-Efficiency Quantum Routing Waveguide

Size Effects of Atomically Precise Gold Nanoclusters in Catalysis

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Precision Chemistry 2023年第1期1卷 14-28页

作者： Site li Xiangsha Du Zhongyu liu Yingwei li Yucai Shao Rongchao jin Department of Chemistry Carnegie Mellon UniversityPittsburghPennsylvania 15213United States

The emergence of ligand-protected,atomically precise gold nanoclusters(NCs)in recent years has attracted broad interest in catalysis due to their well-defined atomic structures and intriguing ***,the precise formulas of NCs provide an opportunity to study the size effects at the atomic level without complications by the polydispersity in conventional nanoparticles that obscures the relationship between the size/structure and ***,we summarize the catalytic size effects of atomically precise,thioate-protected gold NCs in the range of tens to hundreds of metal *** catalytic reactions include electrochemical catalysis,photocatalysis,and *** the precise sizes and structures,the fundamentals underlying the size effects are analyzed,such as the surface area,electronic properties,and active *** the catalytic reactions,one or more factors may exert catalytic effects simultaneously,hence leading to different catalytic-activity trends with the size change of *** summary of literature work disentangles the underlying fundamental mechanisms and provides insights into the size *** studies will lead to further understanding of the size effects and shed light on the catalytic active sites and ultimately promote catalyst design at the atomic level.

关键词： atomic precision nanoclusters catalysis size effects electronic structure

Biotransformation ofα-asarone by Alternaria longipes CGMCC 3.2875

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Chinese Journal of Natural Medicines 2021年第9期19卷 700-705页

作者： ZOU Jian ZHANG Shuai ZHAO Huan WANG Yong-heng ZHOU Zheng-Qun CHEN Guo-Dong HU Dan li Ning YAO Xin-Sheng GAO Hao Institute of Traditional Chinese Medicine&Natural Products College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents ofTCM and New Drugs ResearchJinan UniversityGuangzhou 510632China College of Traditional Chinese Materia Medica Shenyang Pharmaceutical UniversityShenyang 110016China College of Traditional Chinese Medicine Jinan UniversityGuangzhou 510632China Integrated Chinese and Western Medicine Postdoctoral Research Station Jinan UniversityGuangzhou 510632China

Biotransformation ofα-asarone by Alternaria longipes CGMCC 3.2875 yielded two pairs of new neolignans,(+)(7 S,8 S,7’S,8’R)iso-magnosalicin(1 a)/(-)(7 R,8 R,7’R,8’S)iso-magnosalicin(1 b)and(+)(7 R,8 R,7’S,8’R)magnosalicin(2 a)/(-)(7 S,8 S,7’R,8’S)magnosalicin(2 b),and four known metabolites,(±)acoraminol A(3),(±)acoraminol B(4),asaraldehyde(5),and 2,4,5-trimethoxybenzoic acid(6).Their structures,including absolute configurations,were determined by extensive analysis of NMR spectra,X-ray crystallography,and quantum chemical ECD *** cytotoxic activity and Aβ_(42)aggregation inhibitory activity of all the compounds were *** 2 displayed significant anti-Aβ_(42)aggregation activity with an inhibitory rate of 60.81%(the positive control EGCG:69.17%).In addition the biotransformation pathway ofα-asarone by Alternaria longipes CGMCC 3.2875 was proposed.

关键词： Biotransformation α-Asarone Alternaria longipes CGMCC 3.2875 Anti-Aβ_(42)aggregation activity