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Healthy neonate born to a SARS-CoV-2 infected woman:A case report and review of literature

World Journal of Clinical Cases 2020年第23期8卷 6016-6025页

作者： Rong-Yue Wang Ke-Qiong Zheng Bo-Zhong Xu Wei Zhang jin-ge si Chong-Yong Xu Hua Chen Zhang-Ye Xu Xin-Mei Wu Department of Obstetrics and Gynecology The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Department of Obstetrics and Gynecology The Yueqing People’s HospitalWenzhou 325600Zhejiang ProvinceChina Department of Obstetrics and Gynecology The Zhongshan Affiliated Hospital of Sun Yat-Sen UniversityZhongshan 528400Guangdong ProvinceChina Department of Radiology The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Department of Clinical Laboratory The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

BACKGROUND Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a newly discovered coronavirus that has generated a worldwide outbreak of *** people with coronavirus disease-2019(COVID-19)have developed severe illness,and a significant number have ***,little is known regarding infection by the novel virus in pregnant *** herein present a case of COVID-19 confirmed in a woman delivering a neonate who was negative for SARS-CoV-2 and related it to a review of the literature on pregnant women and human coronavirus *** SUMMARY The patient was a 36-year-old pregnant woman in her third trimester who had developed progressive clinical symptoms when she was confirmed as infected with *** the potential risks for both the pregnant woman and the fetus,an emergency cesarean section was performed,and the baby and his mother were separately quarantined and cared *** a result,the baby currently shows no signs of SARS-CoV-2 infection(his lower respiratory tract samples were negative for the virus),while the mother completely recovered from *** Although we presented a single case,the successful result is of great significance for pregnant women with SARS-CoV-2 infection and with respect to fully understanding novel coronavirus pneumonia.

关键词： Novel coronavirus pneumonia SARS-CoV-2 Pregnant woman Neonate Case report

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大青叶蝉在新疆阿勒泰发生为害调查及防治

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昆虫知识 2007年第3期44卷 434-436页

作者：金格斯金恩斯古丽努尔曼苏尔新疆阿勒泰地区林业局阿勒泰836500 新疆富蕴县林业站富蕴836100

对新疆阿勒泰地区大青叶蝉Cicadella viridis(L.)的发生为害进行了调查。该害虫在阿勒泰地区1年发生2代,以卵在杨树、柳树等树干和枝条表皮内越冬。成虫5月上旬羽化后一直到9月下旬在林间草地为害,8月下旬或9月上旬雌成虫在产卵过程严... 详细信息

对新疆阿勒泰地区大青叶蝉Cicadella viridis(L.)的发生为害进行了调查。该害虫在阿勒泰地区1年发生2代,以卵在杨树、柳树等树干和枝条表皮内越冬。成虫5月上旬羽化后一直到9月下旬在林间草地为害,8月下旬或9月上旬雌成虫在产卵过程严重危害树皮,尤其对人工幼林、新造林和苗圃危害非常严重。目前大青叶蝉在当地每年发生面积达1万hm2。为尽快控制其为害,提出了防治建议。

关键词：大青叶蝉杨树柳树发生危害防治阿勒泰地区

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沙棘绕实蝇成虫和幼虫人工饲料研究

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应用昆虫学报 2019年第2期56卷 333-341页

作者：陆燕朱建梅阿地力.沙塔尔吾拉别克金格斯新疆农业大学林学与园艺学院乌鲁木齐830052 布尔津县林业局布尔津836600 阿勒泰地区林业有害生物防治检疫局阿勒泰836599

【目的】本研究建立了沙棘绕实蝇Rhagoletis batava Hering实验种群,为该实蝇生物防治工作奠定基础。【方法】以蜂蜜、蔗糖、酵母膏等为原料,按照不同配比配成饲料,饲养沙棘绕实蝇成虫,观察其对成虫性成熟、交配产卵以及寿命的影响。此... 详细信息

【目的】本研究建立了沙棘绕实蝇Rhagoletis batava Hering实验种群,为该实蝇生物防治工作奠定基础。【方法】以蜂蜜、蔗糖、酵母膏等为原料,按照不同配比配成饲料,饲养沙棘绕实蝇成虫,观察其对成虫性成熟、交配产卵以及寿命的影响。此外,在室内条件(25.00±2.50)℃,光照周期为15L:9D,相对湿度65.00%±5.00%,以蔗糖、酵母膏、麦麸、沙棘果汁(果酱)等为原料,按照不同配比配成饲料,饲养沙棘绕实蝇幼虫,观察其对幼虫历期+化蛹历期、化蛹率及蛹特性的影响。【结果】4种不同配比的饲料对成虫性成熟、交配时间、产卵痕数量和雌雄成虫寿命有显著影响;其中配方D饲养的沙棘绕实蝇成虫性成熟历期、交配时间和产卵痕数量、雌雄成虫寿命分别为(1.78±0.09)d、(4.15±0.03)h、(4.52±0.17)个、(15.47±0.77)d和(15.15±0.79)d,与配方A、B、C均有极显著性差异(P<0.01)。幼虫半人工饲料最佳配方为配方C,其化蛹率、幼虫历期+化蛹历期、蛹长、蛹宽、蛹重分别为50.00%±2.89%、(7.20±0.16)d、(4.74±0.03)mm、(2.45±0.24)mm、(7.21±0.11)mg;全人工饲料最佳配方为配方C,其化蛹率、幼虫历期+化蛹历期、蛹长、蛹宽、蛹重分别为35.00%±7.64%、(5.38±0.18)d、(4.26±0.04)mm、(2.30±0.02)mm、(6.12±0.18)mg;果酱饲料最佳配方为配方C,其化蛹率、幼虫历期+化蛹历期、蛹长、蛹宽、蛹重分别为45.00%±2.89%、(7.11±0.16)d、(4.45±0.07)mm、(2.44±0.02)mm、(6.78±0.21)mg。【结论】沙棘绕实蝇成虫饲养最佳配方为酵母膏20 g、蜂蜜20 g、纯净水160 mL;幼虫半人工饲料最佳配方为蔗糖10 g、酵母膏15 g、麦麸30 g、沙棘果汁50 mL;幼虫全人工饲料最佳配方为蔗糖10 g、酵母膏15 g、麦麸30 g、纯净水50 mL;幼虫饲养最佳果泥饲料配方为沙棘果酱50 g、酵母膏3 g、尼泊尔金0.3 g。

关键词：沙棘绕实蝇人工饲料配方正交试验设计筛选

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布尔津县沙棘绕实蝇的发生动态及习性研究

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新疆农业大学学报 2017年第6期40卷 409-415页

作者：张宁朱建梅陆燕阿地力.沙塔尔金格斯新疆农业大学林学与园艺学院乌鲁木齐830052 阿勒泰地区林业有害生物防治检疫局阿勒泰836599

在室内外定点定时观测沙棘绕实蝇(Rhagoletis batava Hering)的生活史及习性,同时观测了沙棘绕实蝇发生动态与沙棘(Hippophae rhamnoides Linn.)不同品种果实发育之间的关系。结果表明,沙棘绕实蝇在布尔津县一年发生1代,以蛹在土层中越... 详细信息

在室内外定点定时观测沙棘绕实蝇(Rhagoletis batava Hering)的生活史及习性,同时观测了沙棘绕实蝇发生动态与沙棘(Hippophae rhamnoides Linn.)不同品种果实发育之间的关系。结果表明,沙棘绕实蝇在布尔津县一年发生1代,以蛹在土层中越冬。翌年6月中旬沙棘果实膨大期时成虫开始羽化出土,7月上旬沙棘果实变色期时成虫进入羽化高峰期并开始产卵,7月中下旬沙棘果实成熟时为产卵高峰期,同时幼虫开始孵化并危害沙棘果实,8月中旬幼虫进入高峰期,8月下旬为幼虫化蛹高峰期,10月中旬化蛹期结束。沙棘绕实蝇成虫对糖醋液、沙棘果汁及黄色具有较强的趋性,雌虫将卵产在着色的果实上,一般1粒沙棘果实上有1个产卵痕,幼虫在沙棘果实内孵化取食并转果危害,老熟幼虫集中在距树干基部60cm范围树盘内,0~10cm土层中化蛹。经观测当地栽植的5个沙棘品种成熟由早到晚依次为‘状元黄’、‘阿列依’和‘无刺丰’、‘向阳’、‘深秋红’。采摘前受害率由高到低依次为:‘阿列依’55.43%>‘状元黄’37.72%>‘无刺丰’29.10%>‘向阳’21.29%>‘深秋红’0.52%。‘状元黄’沙棘果实着色期与沙棘绕实蝇的发生期相吻合。越早成熟的沙棘品种(‘状元黄’、‘阿列依’)受害程度越重,沙棘绕实蝇产卵物候与晚熟品种‘深秋红’果实成熟期错开,从而使其获得天然的不选择性。

关键词：沙棘沙棘绕实蝇生活史发生动态果实发育

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Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao Hu si Wang Weiqi Zhang jing Qu Guang-Hui Liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

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Challenges in the management of visual and tactile hallucinations in elderly people

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World Journal of Psychiatry 2025年第1期15卷 185-188页

作者： si-Sheng Huang Division of geriatric Psychiatry Department of PsychiatryChanghua Christian HospitalChanghua 500Taiwan Department of Post-Baccalaureate Medicine College of MedicineNational Chung Hsing UniversityTaichung 402Taiwan

This letter provides a concise review of the pertinent literature on visual and tactile hallucinations in elderly *** discussion addresses differential diagnoses and potential underlying mechanisms,as well as the psychopathology associated with tactile hallucinations,and emphasizes the necessity for invest-igation into the possibility of coexisting delusional infestation(parasitosis).These symptoms frequently manifest in patients with primary psychotic disorders,organic mental disorders,and substance use *** proposed pathophy-siological mechanisms may involve dopaminergic imbalances and dysfunction of the striatal dopamine transporter.

关键词： Delusional infestation Dementia Haptic hallucination Scratching behavior Tactile hallucination Visual hallucination Alzheimer’s disease

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乙酯类挥发物及诱剂对沙棘绕实蝇的引诱效果

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新疆农业科学 2019年第8期56卷 1518-1526页

作者：朱建梅陆燕李岚洁阿地力·沙塔尔吾拉别克金格斯新疆农业大学林学与园艺学院乌鲁木齐830052 布尔津县林业局新疆布尔津836600 阿勒泰地区林业有害生物防治检疫局新疆阿勒泰836599

【目的】沙棘绕实蝇Rhagoletis batava Hering是近年来在新疆阿勒泰地区新发现的沙棘果实重要害虫,研究沙棘绕实蝇监测和绿色防控的新途径。【方法】在田间悬挂黄板组合不同乙酯类挥发物及诱剂对沙棘绕实蝇进行诱捕试验。以黄板、三角... 详细信息

【目的】沙棘绕实蝇Rhagoletis batava Hering是近年来在新疆阿勒泰地区新发现的沙棘果实重要害虫,研究沙棘绕实蝇监测和绿色防控的新途径。【方法】在田间悬挂黄板组合不同乙酯类挥发物及诱剂对沙棘绕实蝇进行诱捕试验。以黄板、三角形诱捕器、实蝇专用蘑菇形诱捕器、白色粘虫板作为载体测试其对沙棘绕实蝇的引诱剂效果。【结果】经单因素方差分析,黄板作为载体,与其他处理相比诱捕量具有极显著差异(PRDKS>月桂酸乙酯=十四酸乙酯=棕榈酸乙酯=桔小实蝇引诱剂。【结论】沙棘绕实蝇引诱剂组合黄板对沙棘绕实蝇成虫具有极好的引诱效果,并筛选出一种挥发物RDKS对沙棘绕实蝇两性成虫均有较好的引诱效果,可作为沙棘绕实蝇引诱剂的成分之一,这两种引诱剂结合黄板可作为沙棘绕实蝇监测和防治的有效手段之一。

关键词：沙棘绕实蝇乙酯类挥发物引诱剂引诱效果

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Effect of Particle size on the Hysteretic Behavior and Magnetocaloric Effect of La_(0.5)Pr_(0.5)Fe_(11.4)si_(1.6) Compound

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Acta Metallurgica sinica(English Letters) 2014年第1期27卷 27-30页

作者： Jiaohong Huang Naikun Sun Cuilan Liu Yumei ge Tao Zhang Feng Liu Pingzhan si Baotou Research Institute of Rare Earths School of Science Shenyang Ligong University College of Materials Science and Engineering China Jiliang University

Bulk ***11.4sil.6 compound exhibits a large magnetic-entropy change ASm of 28.1 J/（kg K） for a magnetic-field change from 0 to 1.5 T at the Curie temperature, Tc of 186 K, accompanied by a large magnetic hysteresis of 56 J/kg and a noticeable thermal hysteresis of about 1 K. If the bulk sample is ground into middle-size particles （30-60 tm）, then the thermal hysteresis is almost eliminated and the magnetic hysteresis loss is decreased by 29%, while the large ASm maintains. Especially, fine powder with an average size of 2 tm shows the same Tc as the bulk and does not lose stability. Meanwhile, a comparatively large ASm of 13.9 J/（kg K） and a hysteresis reduction of 70% are attained. The hysteresis reduction can be ascribed to the decrease of internal strains and to the improvement of heat transfer due to the increase of the ratio of the surface area to the volume.

关键词： Magnetocaloric effect Magnetic hysteresis Particle size

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Systematic identification and annotation of multiple-variant compound effects at transcription factor binding sites in human genome

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Journal of genetics and genomics 2018年第7期45卷 373-379页

作者： si-jin Cheng Shuai Jiang Fang-Yuan Shi Yang Ding ge Gao State Key Laboratory of Protein and Plant gene Research School of Life SciencesCenter for BioinformaticsPeking University Beijing Advanced Innovation Center for genomics Peking University

Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple tools have been developed to assess functional effects of genetic variants at TFBSs, they usually assume that each variant works in isolation and neglect the potential ＂interference＂ among multiple variants within the same TFBS. In this study, we presented COPE-TFBS （Context-Oriented Predictor for variant Effect on Transcription Factor Binding site）, a novel method that considers sequence context to accurately predict variant effects on TFBSs. We systematically re-analyzed the sequencing data from both the 1000 genomes Project and the genotype-Tissue Expression （GTEx） Project via COPE-TFBS, and identified numbers of novel TFBSs, transformed TFBSs and discordantly annotated TFBSs resulting from multiple variants, further highlighting the necessity of sequence context in accurately annotating genetic variants.

关键词： Compound effect Transcription factor binding site Variant annotation Bioinformatics genetic variants

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High Fe‑Loading single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

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Nano-Micro Letters 2025年第2期17卷 187-203页

作者： si Chen Fang Huang Lijie Mao Zhimin Zhang Han Lin Qixin Yan Xiangyu Lu Jianlin Shi Department of Cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science Center of Nanocatalytic Medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with *** constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

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