检索结果-南通市图书馆

The psychological trajectory from diagnosis to approaching end of life in patients undergoing hemodialysis in China: A qualitative study

在线全文

学校读者我要写书评

暂无评论

International Journal of Nursing Sciences 2017年第1期4卷 29-33页

作者： Hong-yan Niu jin-feng liu RN Blood Purification CentreThe First People's Hospital of ChangzhouChangzhouChina

Background: In China,the number of patients diagnosed with end-stage renal disease has increased rapidly in recent *** undergoing dialysis treatment often experience psychosocial challenges,such as death anxiety,which may potentially cause patients to withdraw from *** nurses and other practitioners who provide direct care to patients undergoing hemodialysis must understand how these challenges are perceived by patients and affect their daily ***: This article investigated the psychological trajectory and life experiences of hemodialysis patients to provide complementary guidance for nurses and healthcare ***: This study utilized a qualitative descriptive phenomenological *** were collected by conducting semistructured interviews and analyzed by content *** were collected through indepth interviews from May to December *** questions were designed to reveal the life experiences and perspectives of hemodialysis *** were selected by convenience sampling approach and recruited from outpatients receiving treatment in a blood-purification center in Jiangsu Province,***: Twenty-three participants were *** stages were extracted from the interview data:(1) afraid stage,(2) adapted stage,and (3) depression ***,three corresponding stages of physiological status were identified: (1) induced stage,(2) stable stage,and (3) severe complications or approaching-end-of-life ***: Patients undergoing dialysis exhibited differing psychological statuses at different physical ***,nurses must assess the psychophysiological symptoms of patients and design individual care plans for each *** studies should focus on developing stage-specific nursing-care protocols.

关键词： Patients undergoing hemodialysis Psychological trajectory Qualitative research

A New Approach to Development of Composite Web Services

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wuhan University Journal of Natural Sciences 2006年第1期11卷 211-216页

作者： YANG Yan-ping TAN Qing-ping YU jin-shan liu feng College of Computer National University of Defense Technology Changsha 410073 Hunan China

With the requirement for complex Web Services steadily increasing, there is a growing interest for reusing basic, existing Web Services to composite new ones. We present a composite Web Services development approach driven by model driven architecture （MDA） ,using UML（Unified Modeling Language） class diagram to model structure HM （Plateform Independent Platform） and UML activity diagram to model behavior PIM, then by model transformation converting the PIMs to specific Web Services specification platforms and execution platform to get the corresponding PSMs （platform specific models）. The main contributions of this paper are the all-around solution to Web Services composition development and the transformation rules for structure and behavior model of Web Services between PIMs and PSMs.

关键词： Web service composition MDA model transformation UML

Chinese Association for the Study of Pain:Expert consensus on chronic postsurgical pain

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第9期9卷 2090-2099页

作者： Yi-Ming liu Yi feng Yan-Qing liu Yan Lv Yuan-Chang Xiong Ke Ma Xian-Wei Zhang jin-feng liu Yi jin Hong-Guang Bao Min Yan Tao Song Qing liu Department of Algology Peking University People’s HospitalBeijing 100044China Department of Algology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Department of Algology Air Force Medical University of PLAXi’an 710032Shaanxi ProvinceChina Department of Anesthesiology Changhai HospitalNaval Military Medical UniversityShanghai 200433China Department of Algology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Algology The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Algology Affiliated Jinling HospitalMedical School of Nanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Anesthesiology Nanjing First HospitalNanjing Medical UniversityNanjing 210006Jiangsu ProvinceChina Department of Anesthesiology The Second Affiliated Hospital of Zhejiang University school of MedicineHangzhou 310058Zhejiang ProvinceChina Department of Algology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Algology The Affiliated T.C.M Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

Chronic postsurgical pain is a common surgical complication that severely reduces a patient’s quality of *** perioperative interventions and management strategies have been developed for reducing and managing chronic postsurgical *** the leadership of the Chinese Association for the Study of Pain,an editorial committee was formed for chronic postsurgical pain diagnosis and treatment by experts in relevant *** editorial committee composed the main content and framework of this consensus and established a working *** working group conducted literature review(1989-2020)using key words such as“surgery”,“post-surgical”,“post-operative”,“pain”,“chronic”,and“persistent”in different databases including MEDLINE,EMBASE,PubMed,Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic *** publications in the English language were *** types of literature included systematic reviews,randomized controlled studies,cohort studies and case *** consensus was written based on clinical practice combined with literature *** first draft of the consensus was rigorously reviewed and edited by all the editorial committee experts before being *** level of evidence was assessed by methodological experts based on the Oxford Centre for Evidence-Based Medicine Levels of *** strength of recommendation was evaluated by all editorial committee experts,and the opinions of most experts were adopted as the final *** recommendation level“strong”generally refers to recommendations based on high-level evidence and consistency between clinical behavior and expected *** recommendation level“weak”generally refers to the uncertainty between clinical behavior and expected results based on low-level evidence.

关键词： Chronic postsurgical pain Treatment Interventional Prevention

POLYBINAPHTHYLS INCORPORATING (R)-2,2'-BINAPHTHO-20-CROWN-6 AND NAPHTHYL MOITIES

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2006年第6期24卷 619-625页

作者： Dan Zhu Yi-xiang Cheng Xiao-wei Zou Ling-wu Chen jin-feng Song Zhi-liu Wang College of Chemistry and Chemical Engineering Nanjing University Nanjing 210093 China

Chiral polymer was synthesized by the polymerization of （R）-6,6＇-bistributylstannyl-2,2＇-binaphtho-20-crown-6 （M-1） with 1,4-dibromo-2,3-bisbutoxy-naphthyl （M-2） by Pd（PPhs）4 catalyzed Stille coupling reaction. Both monomer and polymer were analyzed by NMR, MS, FT-IR, UV, polarimetry, DSC-TGA, CD, fluorescent spectroscopy and GPC. The major difference between monomer and polymer is that a long wavelength Cotton Effect was observed for the polymer due to its more extended conjugation in the repeating unit and a highly rigid backbone in the polymer chain. Polymer has strong blue fluorescence due to the efficient energy migration from the extended n-electronic structure of the repeating unit of the polymer to the chiral binaphthyl core and is expected to have potential application in the materials of fluorescent sensors and chiral chromatographic packing for resolution ofracemic amino acid.

关键词： (R)-2,2'-Binaphtho-20-crown-6 Chiral polymer Fluorescence Stille reaction.

Efficacy of different antibiotics in treatment of children with respiratory mycoplasma infection

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第23期9卷 6717-6724页

作者： Mei-Ying Zhang Yan Zhao jin-feng liu Guo-Ping liu Rui-Yun Zhang Li-Min Wang Department of Pediatrics Qingdao Municipal HospitalQingdao 266011Shandong ProvinceChina Department of ICU Jinan City People’s HospitalJinan 271199Shandong ProvinceChina Department of Interventional Radiology Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Respiratory infections in children are common pediatric diseases caused by pathogens that invade the respiratory *** are considerably susceptible to Mycoplasma pneumoniae *** has been widespread clinical attention on treatment strategies for this *** To analyze the clinical efficacy of different antibiotics in treating pediatric respiratory mycoplasma *** We included 106 children with a confirmed diagnosis of respiratory mycoplasma infection who were admitted to our hospital from April 2017 to July 2019 and grouped them using a random number *** them,53 children each received clarithromycin or *** clinical efficacy of both drugs was evaluated and *** performed the multiplex polymerase chain reaction(MP-PCR)test and determined the MP-PCR negative rate in children after the end of the treatment *** compared the incidence of toxic and side effects,including nausea,diarrhea,and abdominal pain;further,we recorded the length of hospitalization,antipyretic time,and drug ***,we evaluated and compared the compliance of the children during *** The erythromycin group showed a significantly higher total effective rate of clinical treatment than the clarithromycin ***-PCR test results showed that the clarithromycin group had a significantly higher MP-PCR negative rate than the erythromycin ***,children in the clarithromycin group had shorter fever time,shorter hospital stays,and lower drug costs than those in the erythromycin *** clarithromycin group had a significantly higher overall drug adherence rate than the erythromycin *** incidence of toxic and side effects was significantly lower in the clarithromycin group than in the erythromycin group(P<0.05).CONCLUSION Our findings indicate that clarithromycin has various advantages over erythromycin,including higher application safety,stronger mycoplasma clearance,and higher medicatio

关键词： Clarithromycin Erythromycin Mycoplasma respiratory infection Children Clinical efficacy Drug compliance Toxic side effects

Lycium barbarum extract promotes M2 polarization and reduces oligomeric amyloid-β-induced inflammatory reactions in microglial cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第1期17卷 203-209页

作者： Zhong-Qing Sun jin-feng liu Wei Luo Ching-Hin Wong Kwok-Fai So Yong Hu Kin Chiu Department of Ophthalmology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administrative RegionChina Guangdong-Hong Kong-Macao Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina Department of Orthopaedics&Traumatology The University of Hong KongHong Kong Special Administrative RegionChina

Lycium barbarum(LB)is a traditional Chinese medicine that has been demonstrated to exhibit a wide variety of biological functions,such as antioxidation,neuroprotection,and immune *** of the main mechanisms of Alzheimer’s disease is that microglia activated by amyloid beta(Aβ)transform from the resting state to an M1 state and release pro-inflammatory cytokines to the surrounding *** the present study,immortalized microglial cells were pretreated with *** extract for 1 hour and then treated with oligomeric Aβfor 23 *** results showed that LB extract significantly increased the survival of oligomeric Aβ-induced microglial cells,downregulated the expression of M1 pro-inflammatory markers(inducible nitric oxide synthase,tumor necrosis factorα,interleukin-6,and interleukin-1β),and upregulated the expression of M2 anti-inflammatory markers(arginase-1,chitinase-like protein 3,and interleukin-4).LB extract also inhibited the oligomeric Aβ-induced secretion of tumor necrosis factorα,interleukin-6,and interleukin-1βin microglial *** results of in vitro cytological experiments suggest that,in microglial cells,LB extract can inhibit oligomeric Aβ-induced M1 polarization and concomitant inflammatory reactions,and promote M2 polarization.

关键词： Alzheimer’s disease amyloid-β anti-inflammatory factors Lycium barbarum extract M1 microglia M2 microglia neuroinflammation proinflammatory factors

Study on the relationship between nonresolving inflammation and tumor

在线全文

学校读者我要写书评

暂无评论

Precision Medicine Research 2019年第3期1卷 66-71页

作者： jin-feng liu Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin 300171China

Due to persistent or low-intensity stimulation,tissue cells are in a state of injury for a long time,and the inflammatory state continues,eventually leading to nonresolving *** this nonresolving inflammation,various inflammatory mediators and inflammatory cells act on tissue cells,and tumors are easily ***,the unique microenvironment of the tumor further aggravates the development of uncontrolled *** a vicious circle is *** this paper,we explored the mechanism of inflammatory mediators,inflammatory cells and tumors in nonresolving inflammation from the relationship between nonresolving inflammation and tumors,and provided some new ideas for the prevention and treatment of tumors.

关键词： Nonresolving inflammation Tumor Inflammatory mediator Inflammatory cell

Study on the interaction between inflammation and tumor microenvironment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tumor Microenvironment Research 2019年第1期1卷 8-13页

作者： jin-feng liu Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin 300171China.

In recent years,through the study of tumor microenvironment,it is found that inflammation plays an important role in the occurrence of *** relationship between inflammation and tumors is becoming more and more clear:the long-term existence of uncontrollable inflammation can promote *** occurrence of the tumor microenvironment formed by the tumor and other surrounding cells also promotes further uncontrolled development of *** on the relationship between inflammation and tumor microenvironment,this paper describes the tumor microenvironment and its characteristics,the role of several major mediators in inflammation on tumors,and provides a new strategy for the precise immunotherapy of tumors.

关键词： Inflammation Tumor Tumor microenvironment Interaction

Anti-tumor research progress of Herba Hedyotidis Diffusae

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Precision Medicine Research 2020年第1期2卷 11-16页

作者： jin-feng liu Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin 300060China.

Cancer,as one of the major public health problems in the world,dramatically harms human *** recent years,studies have found that Herba Hedyotidis Diffusae not only plays a huge role in anti-infection but also has a strong effect on *** studies have shown that the components contained in Herba Hedyotidis Diffusae have different levels of antitumor results in multiple *** article summarizes the antitumor elements in Herba Hedyotidis Diffusae,and describes the antitumor mechanism of Herba Hedyotidis *** new ideas for further clinical use.

关键词： Herba Hedyotidis Diffusae Antitumor Mechanism Traditional Chinese medicine