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Comparative study between Embosphere®and Marine gel®as embolic agents for chemoembolization of hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 102-109页

作者： Hyo-cheol kim jin Woo Choi Department of Radiology Seoul National University HospitalSeoul 03080South Korea

BACKGROUND While gelatin sponge particles and calibrated microspheres are commonly used as embolic materials in conventional transarterial chemoembolization(cTACE),direct comparisons between these embolic agents are *** To compare the efficacy and safety of superselective cTACE using Embosphere®or Marine gel®in patients with early-stage hepatocellular carcinoma(HCC).METHODS This retrospective study included 70 patients with small(<4 cm)HCC who underwent cTACE with Embosphere®(n=33)or Marine gel®(n=37)as the embolic agent at a single center between March 2021 and July *** radiologic images and clinical data were retrospectively reviewed,with an emphasis on tumor response,procedure-related complications,and local tumor *** primary index tumor was assessed on a 1-mo follow-up image,and local progression-free survival was obtained using the Kaplan-Meier method and was compared by the log-rank *** The median tumor size of both groups was 1.5 cm,and 69 patients achieved a complete response one month after *** cumulative local recurrence rate at 12 mo was 15.5%in the Embosphere®group and 14.4%in the Marine gel®*** local progression-free survival was not significantly different between the two groups(P=0.83).In the multivariate analysis,high serum alphafetoprotein was the only significant poor prognostic factor for local tumor progression(P=0.01).Postembolization syndrome occurred in 36.4%of the Embosphere®group and 35.1%of the Marine gel®group,and there were no cases of biloma,biliary duct dilation,or liver abscess in either *** Calibrated gelatin sponge particles(Marine gel®)and calibrated microspheres(Embosphere®)have similar outcomes in terms of tumor response for superselective cTACE of small HCC.

关键词： Hepatocellular carcinoma Chemoembolization Temporary embolic material Permanent embolic material Tumor response

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Chemical and mechanical properties of stainless, environment-friendly, and nonflammable Mg alloys (SEN alloys): A review

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Journal of Magnesium and Alloys 2024年第3期12卷 841-872页

作者： Jong Un Lee Hyun Ji kim Sang-cheol jin Ye jin kim Young Min kim Bong Sun You Jun Ho Bae Sung Hyuk Park Advanced Metals Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Metallurgical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Missile Research Institute Agency for Defense DevelopmentDaejeon 34060Republic of Korea

This review article provides overall understanding of stainless,environment-friendly,and nonflammable Mg alloys(SEN alloys)recently developed at the Korea Institute of Materials *** alloys are produced by adding small amounts of Ca and Y(each<1 wt%)into commercial Mg–Al based alloys,resulting in exceptional ignition and corrosion resistances and impressive mechanical *** main advantages of SEN alloys are as follows.(1)A dense multi-oxide layer of SEN alloys comprising MgO,CaO,and Y_(2)O_(3) impedes the outward dispersion of Mg vapor and the inward penetration of O_(2) during oxidation,thereby enhancing the oxidation and ignition resistances.(2)The presence of Ca-and Y-based second-phase particles in SEN alloys can enhance their corrosion resistance because Ca-containing particles prevent the spread of corrosion,and the replacement of Al-containing particles with less noble ones containing Y(e.g.,Al–Mn–Y or Al–Y particles)retards corrosion.(3)The addition of minor amounts of Ca and Y renders excellent mechanical properties due to improved strengthening *** enhanced properties are attributed to more pronounced dynamic recrystallization and grain refining behaviors caused by the second-phase particles during extrusion.(4)Despite the presence of various types of second-phase particles,the fatigue properties of SEN9 alloys are similar to those of commercial AZ91 alloys.(5)Simultaneous introduction of Ca and Y suppresses the formation of Mg17Al12 discontinuous precipitates during aging,leading to the enhanced elongation of aged SEN alloys.(6)Adding mischmetal into the SEN9 alloy leads to a six-fold enhancement in ***,the studies conducted on SEN alloys demonstrate their excellent ignition and corrosion resistances and mechanical properties,which broaden the industrial applications of Mg alloys by addressing their inherent weaknesses.

关键词： SEN magnesium alloy Corrosion resistance Ignition resistance Mechanical properties Extrudability.

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Random pinhole attenuator for high-power laser beams

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High Power Laser Science and Engineering 2024年第3期12卷 116-121页

作者： Seong cheol Park Hyeok Yun jin Woo Yoon Seong Ku Lee Jae Hee Sung Il Woo Choi Chang Hee Nam Kyung Taec kim Department of Physics and Photon Science Gwangju Institute of Science and TechnologyGwangjuRepublic of Korea Center for Relativistic Laser Science Institute for Basic ScienceGwangjuRepublic of Korea Advanced Photonics Research Institute Gwangju Institute of Science and TechnologyGwangjuRepublic of Korea

The intensity attenuation of a high-power laser is a frequent task in the measurements of optical *** intensity can be attenuated by inserting an optical element,such as a partial reflector,polarizer or absorption *** devices are,however,not always easily applicable,especially in the case of ultra-high-power lasers,because they can alter the characteristics of a laser beam or become easily *** this study,we demonstrated that the intensity of a laser beam could be effectively attenuated using a random pinhole attenuator(RPA),a device with randomly distributed pinholes,without changing the beam *** this device,a multi-PW laser beam was successfully attenuated and the focused beam profile was measured without any alterations of its *** addition,it was confirmed that the temporal profile of a laser pulse,including the spectral phase,was ***,the RPA possesses significant potential for a wide range of applications.

关键词： high-power laser intensity attenuation laser diagnostics

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Boosted Lithium-Ion Transport Kinetics in n-Type Siloxene Anodes Enabled by Selective Nucleophilic Substitution of Phosphorus

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Nano-Micro Letters 2024年第10期16卷 618-637页

作者： Se In kim Woong-Ju kim jin Gu Kang Dong-Wan kim School of Civil Environmental and Architectural EngineeringKorea University02841 SeoulSouth Korea Nanophotonics Research Center Korea Institute of Science and Technology02792 SeoulSouth Korea

Doped two-dimensional(2D)materials hold significant promise for advancing many technologies,such as microelectronics,optoelectronics,and energy ***,n-type 2D oxidized Si nanosheets,namely n-type siloxene(n-SX),are employed as Li-ion battery *** thermal evaporation of sodium hypophosphite at 275℃,P atoms are effectively incorporated into siloxene(SX)without compromising its 2D layered morphology and unique Kautsky-type crystal ***,selective nucleophilic substitution occurs,with only Si atoms being replaced by P atoms in the O_(3)≡Si-H *** resulting n-SX possesses two delocalized electrons arising from the presence of two electron donor types:(i)P atoms residing in Si sites and(ii)H *** doping concentrations are varied by controlling the amount of precursors or their mean free *** at 2000 mA g^(-1),the n-SX electrode with the optimized doping concentration(6.7×10^(19) atoms cm^(-3))delivers a capacity of 594 mAh g^(-1) with a 73%capacity retention after 500 *** improvements originate from the enhanced kinetics of charge transport processes,including electronic conduction,charge transfer,and solid-state *** approach proposed herein offers an unprecedented route for engineering SX anodes to boost Li-ion storage.

关键词： Li-ion battery Two-dimensional N-type siloxene Doping mechanism Kinetics

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Anomaly Detection Using Data Rate of Change on Medical Data

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Computers, Materials & Continua 2024年第9期80卷 3903-3916页

作者： Kwang-cheol Rim Young-Min Yoon Sung-Uk kim Jeong-In kim AI Convergence Research Institute Chosun UniversityGwangju61452Republic of Korea Interdisciplinary Program of Architectural Studies Chonnam UniversityGwangju61186Republic of Korea AINTCHAIN SOFT Co. Ltd.Mokpo-si58750Republic of Korea BK21 Human Resources Development Project Group Chosun UniversityGwangju61452Republic of Korea

The identification and mitigation of anomaly data,characterized by deviations from normal patterns or singularities,stand as critical endeavors in modern technological landscapes,spanning domains such as Non-Fungible Tokens(NFTs),cyber-security,and the burgeoning *** paper presents a novel proposal aimed at refining anomaly detection methodologies,with a particular focus on continuous data *** essence of the proposed approach lies in analyzing the rate of change within such data streams,leveraging this dynamic aspect to discern anomalies with heightened precision and *** empirical evaluation,our method demonstrates a marked improvement over existing techniques,showcasing more nuanced and sophisticated result ***,we envision a trajectory of continuous research and development,wherein iterative refinement and supplementation will tailor our approach to various anomaly detection scenarios,ensuring adaptability and robustness in real-world applications.

关键词： Anomaly data anomaly detection medical anomaly data cyber security rate of change

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Vastly Synergistic Fe_(2)CuNiS_(4)-Nanoarchitectures Anchored 2D-Nano-Sandwich Derived from Flower-Like-CuFeS_(2)/N-Graphene and Cube-Like-NiFeS_(2)/N-CNTs for Water Oxidation and Nitrophenol Reduction

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Energy & Environmental Materials 2024年第6期7卷 274-289页

作者： Gopiraman Mayakrishnan Ramkumar Vanaraj Junpeng Xiong Muhammad Farooq Azeem Ullah Keqin Zhang Seong cheol kim Ick Soo kim Nano Fusion Technology Research Group Division of Molecules and PolymersInstitute for Fiber Engineering(IFES)Interdisciplinary Cluster for Cutting Edge Research(ICCER)Shinshu UniversityTokida 3-15-1UedaNagano 386-8567Japan School of Chemical Engineering Yeungnam UniversityGyeongsan 38541Korea Graduate School of Medicine Scienceand TechnologyShinshu UniversityTokida 3-15-1UedaNagano 386-8567Japan National Engineering Laboratory for Modern Silk College of Textile and Clothing EngineeringSoochow UniversitySuzhou 215123China

Surface area,pore properties,synergistic behavior,homogenous dispersion,and interactions between carbon matrix and metal-nanostructures are the key factors for achieving the better performance of carbon-metal based(electro)***,the traditional hydro-or solvothermal preparation of(electro)catalysts,particularly,bi-or tri-metallic nanostructures anchored graphene(G)or carbon nanotubes(CNTs),often pose to poor metal–support interaction,low synergism,and patchy *** first,bimetallic flower-like-CuFeS_(2)/NG and cube-like-NiFeS_(2)/NCNTs nanocomposites were prepared by solvothermal *** resultant bimetallic nanocomposites were employed to derive the 2D-nano-sandwiched Fe_(2)CuNiS_(4)/NGCNTs-SW(electro)catalyst by a very simple and green urea-mediated“mix-heat”*** desired physicochemical properties of Fe_(2)CuNiS_(4)/NGCNTs-SW such as multiple active sites,strong metal-support interaction,homogenous dispersion and enhanced surface area were confirmed by various microscopic and spectroscopic *** the best of our knowledge,this is the first urea-mediated“mix-heat”method for preparing 2D-nano-sandwiched carbon-metal-based(electro)*** Fe_(2)CuNiS_(4)/NGCNTs-SW was found to be highly effective for alkaline-mediated oxygen evolution reaction at low onset potential of 284.24 mV,and the stable current density of 10 mA cm^(−2) in 1.0 m KOH for 10 ***,the Fe_(2)CuNiS_(4)/NGCNTs-SW demonstrated excellent catalytic activity in the reduction of 4-nitrophenol with good kapp value of 87.71×10^(−2)s^(-1)and excellent reusability over five ***,the developed urea-mediated“mix-heat”method is highly efficient for the preparation of metal-nanoarchitectures anchored 2D-nano-sandwiched(electro)catalysts with high synergism,uniform dispersion and excellent metal-support interaction.

关键词： (electro)catalyst metal-sulfide nanoarchitectures mix-heat N-graphene/NCNTs synergistic effect urea

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Tribological behavior of TiN,AlTiN,and AlTiCrN coatings in atmospheric and vacuum environments

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Friction 2024年第11期12卷 2611-2626页

作者： Youn-Hoo HWANG Kuk-jin SEO Tae-Hyeong kim You jin MIN Yuzhen LIU Dae-Eun kim Department of Mechanical Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Mechatronics and Energy Engineering Ningbo Tech UniversityNingbo 315211China

In this study,the tribological characteristics of TiN,AlTiN,and AlTiCrN coatings sliding against a SUS420J1 stainless steel pin were investigated in atmospheric and vacuum *** coatings were deposited on SUS440C substrates using the arc-physical vapor deposition *** friction and wear behavior of the coatings were evaluated based on the systematic analyses of the friction coefficient data as well as the physical and chemical state of the wear *** results revealed that the friction coefficients of the SUS440C specimen and AlTiCrN coatings increased,whereas those of the TiN and AlTiN coatings decreased when the environment was changed from atmospheric to *** was confirmed that the formation of an oxide layer and adsorption of oxides on the surface were dominant factors that influenced the tribological behavior in the atmospheric *** the other hand,the compatibility,oxidation inhibition,and droplets of the surface mainly affected the frictional characteristics in the vacuum *** results of this work are expected to aid in the selection of proper coating materials for tribological systems operating in a vacuum.

关键词： friction wear coating vacuum TiN

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Ag-GST/HfO_(x)-based unidirectional threshold switching selector with low leakage current and threshold voltage distribution for high-density cross-point arrays

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Rare Metals 2024年第1期43卷 280-288页

作者： Kyoung-Joung Yoo Dae-Yun Kang Nahyun kim Ho-jin Lee Ta-Hyeong kim Taeho kim Tae Geun kim School of Electrical Engineering Korea UniversitySeoul 02841Republic of Korea

The use of electrochemical-metallization-based volatile threshold switching selectors in cross-point arrays has been widely explored owing to their high on-off ratios and simple ***,these devices are unsuitable for cross-point architectures because of the difficulty in controlling the random filament formation that results in large fluctuations in the threshold voltage during *** this study,we investigated the unidirectional threshold transition characteristics associated with an Ag/GST/HfO_(x)/Pt-based bilayer selector and demonstrated the occurrence of a low leakage current(<1×10^(-11) A) and low distribution of the threshold voltage(Δ0.11 V).The bilayer structure could control the filament formation in the intermediate state through the insertion of an HfO_(x) tunneling *** stacking a bilayer selector with NiO_(x)based resistive random-access memory,the leakage and programming currents of the device could be significantly *** the crossbar array configuration,we performed equivalent circuit analysis of a one-selector oneresistor(1S1R) devices and estimated the optimal array size to demonstrate the applicability of the proposed *** maximum acceptable crossbar array size of the 1S1R device with the Ag/GST/HfO_(x)/Pt/Ti/NiO_(x)/Pt structure was 5.29×10^(14)(N^(2),N=2.3×10^(7)).

关键词： Selector device Tunneling barrier Threshold switching Sputtering 1S1R Cross-point array

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Construction of a High‑Performance Composite Solid Electrolyte Through In‑Situ Polymerization within a Self‑Supported Porous Garnet Framework

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Nano-Micro Letters 2024年第5期16卷 56-70页

作者： An‑Giang Nguyen Min‑Ho Lee Jaekook kim Chan‑jin Park Department of Materials Science and Engineering Chonnam National University77 Yongbong‑roBuk‑guGwangju 61186South Korea

Composite solid electrolytes(CSEs)have emerged as promising candidates for safe and high-energy–density solid-state lithium metal batteries(SSLMBs).However,concurrently achieving exceptional ionic conductivity and interface compatibility between the electrolyte and electrode presents a significant challenge in the development of high-performance CSEs for *** overcome these challenges,we present a method involving the in-situ polymerization of a monomer within a self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZT)to produce the *** synergy of the continuous conductive LLZT network,well-organized polymer,and their interface can enhance the ionic conductivity of the CSE at room ***,the in-situ polymerization process can also con-struct the integration and compatibility of the solid electrolyte–solid electrode *** synthesized CSE exhibited a high ionic conductivity of 1.117 mS cm^(-1),a significant lithium transference number of 0.627,and exhibited electrochemical stability up to 5.06 V ***/Li+at 30℃.Moreover,the Li|CSE|LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) cell delivered a discharge capacity of 105.1 mAh g^(-1) after 400 cycles at 0.5 C and 30℃,corresponding to a capacity retention of 61%.This methodology could be extended to a variety of ceramic,polymer electrolytes,or battery systems,thereby offering a viable strategy to improve the electrochemical properties of CSEs for high-energy–density SSLMBs.

关键词： Scalable tape-casting method Self-supported porous Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12) Composite solid electrolyte LiF-and B-rich interphase layers

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ROS-induced metabolic reprogramming to one-carbon metabolism and S-adenosylmethionine-mediated epigenetic modification in IL-10-producing B cells for the resolution of pneumonia

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Cellular & Molecular Immunology 2024年第2期21卷 203-204页

作者： Sujin Lee Tae jin kim Department of Immunology Sungkyunkwan University School of MedicineSuwon16419Republic of Korea

B cells have an essential immunoregulatory function,which is mediated by the secretion of IL-10 and TGFβand interaction with activated CD4^(+)T *** antibody-independent function of B cells contributes to ameliorating autoimmune diseases or infection-induced tissue *** this Cellular and Molecular Immunology issue,Fu et *** that regulatory B(Breg)cells play a critical role in resolving Pseudomonas aeruginosa-induced pneumonia[1].

关键词： metabolism pneumonia Immunology

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