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Mid-ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm and sustained ventricular tachycardia： a case report and literature review

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Chinese Medical Journal 2011年第11期124卷 1754-1757页

作者： GAO Xiao-jin KANG lian-ming zhang Jian DOU Ke-fei YUAN Jian-song YANG Yue-jin Department of Cardiology Cardiovascular Institute and FuwaiHospital Chinese Academy of Medical Sciences & Peking UnionMedical College Beijing 100037 China

The case is a 54-year-old man with hypertrophic cardiomyopathy, mid-ventricular obstruction, apical aneurysm, and recurrence sustained monomorphic ventricular tachycardia （VT）. A coronary angiogram revealed myocardial bridging located in the middle of the left anterior descending coronary artery （LAD）, and the left ventriculogram showed an hour-glass appearance of the left ventricular cavity. There was a significant pressure gradient of 60 mmHg across the mid-ventricular obliteration at rest. A successful myectomy of the inappropriate hypertrophy myocardium and excision of the apical aneurysm were performed. Pathologic analysis demonstrated fibrosis in the apical aneurysm and thickened and narrowed vessels in the adjacent area. During the follow-up of eighteen months, the patient remained clinically stable and free from arrhythmic recurrence.

关键词： hypertrophic cardiomyopathy aneurysm ventricular tachycardia

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非自治动力系统的原像熵

数学学报（中文版） 2005年第4期48卷 693-702页

作者：张金莲朱玉峻何连法河北师范大学数学与信息科学学院石家庄050016

本文对紧致度量空间上的连续自映射序列应用生成集和分离集引入了点原像熵、原像分枝熵以及原像关系熵等几类原像熵的定义并进行了研究.主要结果是:(1) 证明了这些熵都是等度拓扑共轭不变量.(2)讨论了这些原像熵之间及它们与拓扑熵之间... 详细信息

本文对紧致度量空间上的连续自映射序列应用生成集和分离集引入了点原像熵、原像分枝熵以及原像关系熵等几类原像熵的定义并进行了研究.主要结果是:(1) 证明了这些熵都是等度拓扑共轭不变量.(2)讨论了这些原像熵之间及它们与拓扑熵之间的关系,得到了联系这些熵的不等式.(3)证明了对正向可扩的连续自映射序列而言, 两类点原像熵相等,原像分枝熵与原像关系熵也相等.(4)证明了对(a).由闭Riemann 流形上的一个扩张映射经充分小的C1-扰动生成的自映射序列,以及(b).有限图上等度连续的自映射序列,有零原像分枝熵.

关键词：连续自映射序列拓扑熵原像熵

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广义线性图嵌入分布的收敛速度

数学学报（中文版） 2024年第5期67卷 947-961页

作者：张金莲彭旭辉陈琪瑶湖南财政经济学院数学与统计学院长沙410205 应用统计与数据科学湖南省普通高等学校重点实验室湖南师范大学数学与统计学院长沙410081 湖南第一师范学院数学与统计学院长沙410002

线性图序列的亏格分布已经被研究了30多年.此前,大部分文献关注于寻找图序列嵌入分布的具体表达式、递推关系式或者对数凹的证明.近期的研究表明:对于广义线性图序列{G_(n)^(o)},在一定条件下,当n趋向于无穷时,G_(n)^(o)的嵌入分布会收... 详细信息

线性图序列的亏格分布已经被研究了30多年.此前,大部分文献关注于寻找图序列嵌入分布的具体表达式、递推关系式或者对数凹的证明.近期的研究表明:对于广义线性图序列{G_(n)^(o)},在一定条件下,当n趋向于无穷时,G_(n)^(o)的嵌入分布会收敛于正态分布(参见[***.,2021,127:102175].基于此工作,在类似的条件下,本文证明了其收敛速度的阶为1/√n.同时,论证了该收敛速度估计的最优性.最后,给出了一些具体的例子.

关键词：收敛速度嵌入分布 H-线性图序列正态分布

Integration of perioperative features and intragraft TCF7L2 expression to predict lipid metabolic disorder in liver transplant recipients

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Science China Life Sciences 2025年第1期68卷 297-299页

作者： Junbin Zhou Rongli Wei Guanghan Fan Zhengxing lian Xuanyu zhang Linsong Tang Zhetuo Qi Haiyang Xie Shusen Zheng Qiang Wei Xiao Xu Department of Hepatobiliary and Pancreatic Surgery People's Hospital of LishuiAffiliated Lishui Hospital of Wenzhou Medical UniversityThe First Affiliated Hospital of Lishui University NHFPC Key Laboratory of Combined Multi-Organ Transplantation Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryHangzhou First People's Hospital Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of Medicine Department of Urology The Second Affiliated HospitalZhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan (Hangzhou) Hospital Hangzhou Medical College Zhejiang University School of Medicine

Dear Editor, Liver transplantation(LT) is the only curative therapy for patients with endstage liver disease(He et al., 2023; Ling et al., 2022). Post-transplant hypertriglyceridemia(PTHT), which has an incidence of up to 32.8% in 6 months after LT, is one of the major post-transplant complications(Toshima et al., 2020).

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超声波清洗的一种新方法

陕西师范大学学报（自然科学版） 2002年第2期30卷 35-37页

作者：任金莲张明铎牛勇陕西师范大学应用声学研究所陕西西安710062

基于超声波传播的机理 ,提出了一种无需清洗液且有别于常规超声波清洗机理的超声波振动清洗方法 ,并阐明了选取各超声参量时应注意的问题 .实验结果表明 ,该方法简单可靠。

关键词：超声波清洗振动清洗超声波传播机理清洗液清洗机理清洗方法

2种化疗方案治疗晚期上皮性卵巢癌的临床研究

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中国现代医学杂志 2021年第12期31卷 79-82页

作者：张金莲覃世运陈美娟彭芝莲黄秋雅王传静张春花海南省第三人民医院肿瘤科海南三亚572000 中南大学湘雅医院肿瘤科湖南长沙410008

目的探讨不同化学药物治疗(以下简称化疗)方案治疗晚期上皮性卵巢癌的疗效。方法选取2017年7月-2019年6月在海南省第三人民医院就诊的晚期上皮性卵巢癌患者93例,所有患者都是初治且行肿瘤细胞减灭术。术后常规化疗,一组为紫杉醇+卡铂(TC... 详细信息

目的探讨不同化学药物治疗(以下简称化疗)方案治疗晚期上皮性卵巢癌的疗效。方法选取2017年7月-2019年6月在海南省第三人民医院就诊的晚期上皮性卵巢癌患者93例,所有患者都是初治且行肿瘤细胞减灭术。术后常规化疗,一组为紫杉醇+卡铂(TC组),另一组为紫杉醇+顺铂(TP组)。比较不同化疗方案对患者的临床疗效及其主要毒副反应。结果TC组有效率为68.9%(31/45),TP组为70.8%(34/48),差异无统计学意义(P>0.05)。TC组骨髓抑制率(48.9%)高于TP组(35.4%)(P60岁患者的骨髓抑制率比较,差异无统计学意义(P>0.05)。TP组消化道反应发生率(37.5%)高于TC组(24.4%)(P<0.05)。结论TC和TP方案对晚期上皮性卵巢癌均疗效确切,TP组骨髓抑制发生率低于TC组,TP组虽然总体消化道反应发生率高于TC组,但主要是Ⅰ级和Ⅱ级消化道反应,患者尚可耐受。

关键词：上皮性卵巢癌晚期紫杉醇顺铂卡铂化疗后骨髓抑制消化道反应

Activatable chemiluminescence probe based on four-arm PEGconjugated-pyropheophorbide-a for in vivo autofluorescence-free imaging of peroxynitrite

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Science China Chemistry 2025年

作者： Jianmei Ke Lei Ding Ronggui lian Cheng Zheng Wenjun Li Aixian Zheng Yupeng Sun Ming Wu Yongyi Zeng Xiaolong Liu Maochun Hong Xiaolong zhang The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province Mengchao Hepatobiliary Hospital of Fujian Medical University Ganjiang Innovation Academy Chinese Academy of Sciences School of Rare Earths University of Science and Technology of China College of Chemistry Fuzhou University State Key Laboratory of Structure Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences

Peroxynitrite（ONOO-） is a highly reactive nitrogen species that plays pivotal roles in cell signal transduction and physiological or pathological progresses. However, commonly used ONOO-optical imaging probes are still hampered by high background/autofluorescence（fluorescence probe）, short emission wavelength, or poor selectivity in the case of chemiluminescence. Herein,we report a facile method to prepare an activatable chemiluminescence probe（PPA-PEG） with good biocompatibility and functionality for in vivo autofluorescence-free imaging of ONOO-. The PPA-PEG consists of pyropheophorbide-a（PPA）, a typical deep red photosensitizer that acts as both the recognition and signaling element, and 4-arm poly（ethylene glycol）(4-arm PEG), which improves the biosafety and water solubility of probe. These components can self-assemble into nanoparticles（namely PPA-PEG nanoprobe） in aqueous solution. The PPA-PEG nanoprobe showed an ultra-low chemiluminescence signal before interacting with ONOO-, but exhibited good selectivity, high sensitivity and a fast response toward ONOO-. The PPAPEG was successfully applied to image cellular ONOO-changes, as well as the endogenous ONOO-changes in inflammation models and subcutaneous or orthotopic hepatocellular carcinoma（HCC） tumors models in living mice. In vitro and in vivo studies verified the good detection and imaging capabilities of PPA-PEG for peroxynitrite, demonstrating suitable tissue penetration and a high signal-to-background ratio（SBR）. Thus, our nanoprobe can serve as a valuable activatable chemiluminescence imaging tool for studying important peroxynitrite-related chemical and biological applications.

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超声清洗设备输出变压器偏磁分析与控制

陕西师范大学学报（自然科学版） 2007年第3期35卷 44-47页

作者：任金莲牛勇张明铎朱秀丽陕西师范大学应用声学研究所陕西西安710062

从理论上推导了大功率超声波清洗设备输出变压器磁化过程和存在的偏磁现象,用磁化特性与励磁电流及磁通示意图,分析了产生偏磁的原因及主要因素,提出了几种抑制变压器偏磁的方法.结果表明,选用MnZn铁氧体磁芯材料、施加电路平衡及电气... 详细信息

从理论上推导了大功率超声波清洗设备输出变压器磁化过程和存在的偏磁现象,用磁化特性与励磁电流及磁通示意图,分析了产生偏磁的原因及主要因素,提出了几种抑制变压器偏磁的方法.结果表明,选用MnZn铁氧体磁芯材料、施加电路平衡及电气隔离等措施,可抑制偏磁问题,输出变压器励磁电流大幅降低,没有偏磁现象,其工作温度和工作性能稳定,且转换效率高达85%以上.

关键词：超声清洗输出变压器偏磁磁饱和

Einstein Probe discovery of EP240408a: A peculiar X-ray transient with an intermediate timescale

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 222-240页

作者： Wenda zhang Weimin Yuan Zhixing Ling Yong Chen Nanda Rea Arne Rau Zhiming Cai Huaqing Cheng Francesco Coti Zelati Lixin Dai jingwei Hu Shumei Jia Chichuan jin Dongyue Li Paul O’Brien Rongfeng Shen Xinwen Shu Shengli Sun Xiaojin Sun Xiaofeng Wang Lei Yang Bing zhang Chen zhang Shuang-Nan zhang Yonghe zhang Jie An David Buckley Alexis Coleiro Bertrand Cordier Liming Dou Rob Eyles-Ferris Zhou Fan Hua Feng Shaoyu Fu Johan P.U.Fynbo Lluis Galbany Saurabh W.Jha Shuaiqing Jiang Albert Kong Erik Kuulkers Weihua Lei Wenxiong Li Bifang Liu Mingjun Liu Xing Liu Yuan Liu Zhu Liu Chandreyee Maitra Alessio Marino Itumeleng Monageng Kirpal Nandra Jeremy Sanders Roberto Soria lian Tao Junfeng Wang Song Wang Tinggui Wang Zhongxiang Wang Qingwen Wu Xuefeng Wu Dong Xu Yanjun Xu Suijian Xue Yongquan Xue Zijian zhang Zipei Zhu Hu Zou Congying Bao Fansheng Chen Houlei Chen Tianxiang Chen Wei Chen Yehai Chen Yifan Chen Chenzhou Cui Weiwei Cui Yanfeng Dai Dongwei Fan Ju Guan Dawei Han Dongjie Hou Haibo Hu Maohai Huang Jia Huo Zhenqing Jia Bowen Jiang Ge jin Chengkui Li Junfei Li Longhui Li Maoshun Li Wei Li Zhengda Li Tianying lian Congzhan Liu Heyang Liu Huaqiu Liu Fangjun Lu Laidan Luo Jia Ma Xuan Mao Haiwu Pan Xin Pan Liming Song Hui Sun Yunyin Tan Qingjun Tang Yihan Tao Hao Wang Juan Wang Lei Wang Wenxin Wang Yilong Wang Yusa Wang Qinyu Wu Haitao Xu jingjing Xu Xinpeng Xu Yunfei Xu Zhao Xu Changbin Xue Yulong Xue Ailiang Yan Haonan Yang Xiongtao Yang Yanji Yang Juan zhang Mo zhang Wenjie zhang Zhen zhang Zhen zhang Ziliang zhang Donghua Zhao Haisheng Zhao Xiaofan Zhao Zijian Zhao Hongyan Zhou Yilin Zhou Yuxuan Zhu Zhencai Zhu National Astronomical Observatories Chinese Academy of Sciences School of Astronomy and Space Sciences University of Chinese Academy of Sciences Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Institute of Space Sciences (ICE) CSIC Institut d’Estudis Espacials de Catalunya (IEEC) Max Planck Institute for Extraterrestrial Physics Innovation Academy for Microsatellites Chinese Academy of Sciences Department of Physics University of Hong Kong School of Physics and Astronomy University of Leicester School of Physics and Astronomy Sun Yat-sen University Department of Physics Anhui Normal University Shanghai Institute of Technical Physics Chinese Academy of Sciences Physics Department Tsinghua University Nevada Center for Astrophysics University of Nevada Las Vegas Department of Physics and Astronomy University of Nevada Las Vegas South African Astronomical Observatory Department of Astronomy University of Cape Town Department of Physics University of the Free State Université Paris Cité CNRS Astroparticule et Cosmologie Université Paris Cité CEA Paris-Saclay IRFU/DAp-AIM Department of Astronomy Guangzhou University Cosmic Dawn Center (DAWN) Niels Bohr Institute University of Copenhagen Department of Physics and Astronomy Rutgers the State University of New Jersey Institute for Cosmic Ray Research The University of Tokyo ESA/ESTEC Department of Astronomy School of Physics Huazhong University of Science and Technology INAF-Osservatorio Astrofisico di Torino Sydney Institute for Astronomy School of Physics The University of Sydney Department of Astronomy Xiamen University Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Department of Astronomy University of Science and Technology School of Astronomy and Space Sciences University of Science and Technology of China Institute of Deep Space Sciences Deep Space Exploration Laboratory Department of Astronomy School of Physics and Astronomy Yunnan University Shanghai Astronomical Observatory Chi

We report the discovery of a peculiar X-ray transient,EP240408a,by Einstein Probe （EP） and follow-up studies made with EP,Swift,NICER,GROND,ATCA and other ground-based multiwavelength *** new transient was first detected with Wide-field X-ray Telescope （WXT） on board EP on April 8th,2024,manifested in an intense yet brief X-ray flare lasting for *** flare reached a peak flux of 3.9×10-9erg cm-2s-1in 0.5-4 ke V,～300 times brighter than the underlying X-ray emission detected throughout the *** and more precise follow-up observations by EP/FXT,Swift and NICER confirmed the finding of this new *** X-ray spectrum is non-thermal in 0.5-10 ke V,with a power-law photon index varying *** X-ray light curve shows a plateau lasting for ～4 d,followed by a steep decay till becoming undetectable ～10 d after the initial *** on its temporal property and constraints from previous EP observations,an unusual timescale in the range of 7-23 d is found for EP240408a,which is intermediate between the commonly found fast and long-term *** counterparts have been found in optical and near-infrared,with the earliest observation at 17 h after the initial X-ray detection,suggestive of intrinsically weak emission in these *** demonstrate that the remarkable properties of EP240408a are inconsistent with any of the transient types known so far,by comparison with,in particular,jetted tidal disruption events,gamma-ray bursts,X-ray binaries and fast blue optical *** nature of EP240408a thus remains an *** suggest that EP240408a may represent a new type of transients with intermediate timescales of the order of～10 *** detection and follow-ups of more of such objects are essential for revealing their origin.

关键词： X-ray transients ${\bm~{Einstein~~Probe}}$