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Color gradients of spiral disks in the Sloan Digital Sky Survey

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Research in Astronomy and Astrophysics 2009年第10期9卷 1119-1130页

作者： Cheng-Ze Liu Shi-Yin Shen Zheng-Yi Shao Rui-Xiang Chang jin-Liang hou Jun Yin Da-Wei Yang Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Key Laboratory for Astrophysics Shanghai 200234 China Department of Physics Hebei Normal University Shijiazhuang 050016 China

We investigate the radial color gradients of galactic disks using a sample of - 20 000 face-on spiral galaxies selected from the fourth data release of the Sloan Digital Sky Survey （SDSS-DR4）. We combine galaxies with similar concentrations, sizes and luminosities to construct composite galaxies, and then measure their color profiles by stacking the azimuthally averaged radial color profiles of all the member galaxies. Except for the smallest galaxies （R50 〈 3 kpc）, almost all galaxies show negative disk color gradients with mean 9 - r gradient Ggr = -0.006 magkpc-1 and r - z gradient Grz = -0.018 mag kpc^-1. The disk color gradients are independent of the morphological types of galaxies and strongly dependent on the disk surface brightness μd, with lower surface brightness galactic disks having steeper color gradients. We quantify the intrinsic correlation between color gradients and surface brightness as Ggr = -0.011μd ＋ 0.233 and Grz - -0.015μd ＋ 0.324. These quantified correlations provide tight observational constraints on the formation and evolution models of spiral galaxies.

关键词： galaxies spiral -- galaxies statistics -- galaxies evolution -- galaxies fundamental parameters (color gradient, luminosity, radius, surface brightness)

Increased procoagulant activity of red blood cells in the presence of cisplatin

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Chinese Medical Journal 2008年第18期121卷 1775-1780页

作者： LV Cheng-fang YU Hong-juan hou jin-xiao Zhou jin Department of Hematology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China

Background Cisplatin based chemotherapy is a well recognized risk factor for coagulation disorders and thrombosis. The pathophysiological mechanisms by which cisplatin promote thrombosis are not well understood. Methods Red blood cells （RBCs） were separated from peripheral blood of patients with breast cancer （n=10） and healthy adults （n=6） and treated with cisplatin. Coagulation time of RBCs was assessed by one step recalcification time and the productions of thrombin, intrinsic and extrinsic factor Xa were measured in the presence or absence of various concentrations of lactadherin. Exposed phosphatidylserine was stained with lactadherin and observed by confocal microscopy and flow cytometry. Results Neither fresh RBCs nor RBCs treated without cisplatin had potent procoagulant activity. Cisplatin treatment increased procoagulant activity of RBCs in a cell number- and concentration-dependent manner. Exposed phosphatidylserine was stained with lactadherin and after cisplatin treatment, strong fluorescence was revealed by confocal microscopy. Lactadherin bound RBCs from patients with breast cancer increased from （1.9＋0.5）% on control RBCs to （68.0±3.5）% on RBCs treated with 10umol/L cisplatin for 24 hours. Conclusions Cisplatin treatment increases procoagulant activity of RBCs, which have a strong association with exposure of phosphatidylserine. The increased procoagulant activity may contribute to the pathogenesis of thrombophilia during cisplatin based chemotherapy in breast cancer patients.

关键词： procoagulant activity red blood cell phosphatidylserine cisplatin lactadherin

Candidate members of star clusters from LAMOST DR2

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Research in Astronomy and Astrophysics 2015年第8期15卷 1197-1208页

作者： Bo Zhang Xiao-Yan Chen Chao Liu Li Chen Li-Cai Deng jin-Liang hou Zheng-Yi Shao Fan Yang Yue Wu Ming Yang Yong Zhang Yong-Hui hou Yue-Fei Wang Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of Sciences University of Chinese Academy of Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences

In this work, we provide 2189 photometrically- and kinematically-selected candidate members of 24 star clusters from the LAMOST DR2 catalog. We perform two-step membership identification： selection along the stellar track in the colormagnitude diagram, i.e., photometric identification, and selection from the distribution of radial velocities, i.e. the kinematic identification. We find that the radial velocities from the LAMOST data are very helpful in the membership identification. The mean probability of membership is 40% for the sample selected with radial velocity. With these 24 star clusters, we investigate the performance of the radial velocity and metallicity estimated with the LAMOST pipeline. We find that the systematic offsets in radial velocity and metallicity are 0.85 ± 1.26 km s-1and-0.08 ± 0.04 dex, with dispersions of 5.47＋1.16-0.71 km s-1and 0.13＋0.04-0.02 dex, respectively. Finally, we propose that the photometrically-selected candidate members of the clusters covered by the LAMOST footprint should be assigned higher priority so that more candidate stars can be observed.

关键词： open clusters and associations: general—stars: statistics—catalogs—surveys—methods: data analysis

indfulness Meditation for Primary Headache Pain： A Meta-Analysis

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Chinese Medical Journal 2018年第7期131卷 829-838页

作者： Qiang Gu jin-Chao hou Xiang-Ming Fang School of Medicine Zhejiang University Hangzhou Zhejiang 210029 China Department of Anesthesiology School of Medicine The First Affiliated Hospital Zhejiang University Hangzhou Zhejiang 210029 China

Background： Several studies have reported that mindfulness meditation has a potential effect in controlling headaches, such as migraine and tension-type headache; however, its role remains controversial. This review assessed the evidence regarding the effects of mindfulness meditation for primary headache pain. Methods： Only English databases （PubMed, Cochrane Central Register of Controlled Trials [the Cochrane Library], PsyclNFO, Psychology and behavioral science collection, PsyArticles, Web of Science, and Scopus） were searched from their inception to November 2016 with the keywords （＂meditation＂ or ＂mindfulness＂ or ＂vipassana＂ or ＂dzogchen＂ or ＂zen＂ or ＂integrative body-mind training＂ or ＂IBMT＂ or ＂mindfulness-based stress reduction＂ or ＂MBSR＂ or ＂＇mindfulness-based cognitive therapy＂ or ＂MBCT＂ and ＂Headache＂ or ＂Head pain＂ or ＂Cephalodynia＂ or ＂Cephalalgia＂ or ＂Hemicrania＂ or ＂Migraine＂）. Titles, abstracts, and full-text articles were screened against study inclusion criteria： controlled trials of structured meditation programs for adult patients with primary headache pain. The quality of studies included in the meta-analysis was assessed with the Yates Quality Rating Scale. The meta-analysis was conducted with Revman 5.3. Results： Ten randomized controlled trials and one controlled clinical trial with a combined study population of 315 patients were included in the study. When compared to control group data, mindfulness meditation induced significant improvement in pain intensity （standardized mean difference, -0.89; 95% confidence interval, 1.63 to 0.15; P - 0.02） and headache frequency （-0.67; - 1.24 to -0.10; P - 0.02）. In a subgroup analysis of different meditation forms, mindfulness-based stress reduction displayed a significant positive influence on pain intensity （P 〈 0.000）. Moreover, 8-week intervention had a significant positive effect （P 〈 0.000）. Conclusions： Mindfulness meditation may reduce pain intensity and is a promising treatment option tbr pa

关键词： Headache Pain Meta-Analysis Mindfulness Meditation

Wilfoside C3N Promotes Tumor Cell Death by Activating Gammadelta T Cells-Mediated Anti-tumor Immunity

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河北北方学院学报（自然科学版） 2017年第2期33卷 1-10页

作者： hou jin-yu WANG jing Zhangjiakou NO.1 High School Zhangjiakou Hebei Province 075000 China Life Science Research Center Hebei North University Zhangjiukou Hebei Province China

Vδ1^+γδ T lymphocytes are known to play important roles in anti-tumor *** recently reported an anti-tumor activity of wilfoside C3 N,an active component extracted from Chinese medicinal *** the current study,we evaluated the role of Vδ1^+γδ T cells in C3 N anti-tumor activity using an in vitro cell co-culture *** found that C3 N induced the ECA109 tumor cells to undergo apoptosis in the presence of Vδ1^+γδ T *** level of ECA109 apoptosis maximized when both C3 N and Vδ1 + γδ T cells were present,which correlated with the increased expression of Fas on ECA109 and Fas ligand on Vδ1^+γδ T cells induced by C3 *** addition,C3 N also enhanced secretion of cytokines,perforin and granzymes by Vδ1^+γδ T *** observations suggest that activation of Vδ1^+ γδ T cells may play a critical role in C3N-mediated anti-tumor activity.

关键词： wilfoside C3N Vδ1^+gammadelta T cells anti-tumor ECA109 cells

Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship

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Chinese Journal of Natural Medicines 2017年第10期15卷 766-774页

作者： hou jin-Jun SHEN Yao YANG Zhou FANG Lin CAI Lu-Ying YAO Shuai LONG Hua-Li WU Wan-Ying GUO De-An Shanghai Research Center for Modernization of Traditional Chinese Medicine National Engineering Laboratory for TCM Standardization Technology Shanghai Institute of Materia Medica Chinese Academy of Sciences Haike Road 501 Shanghai 201203 China

Euphorbia kansui is a commonly used traditional Chinese medicine for the treatment of edema,pleural effusion,and asthma,*** to the previous researches,terpenoids in *** possess various biological activities,e.g.,anti-virus,anti-allergy,antitumor *** this work,twenty five terpenoids were isolated from ***,including thirteen ingenane-and eight jatrophane-type diterpenoids(with two new compounds,kansuinin P and Q)and four *** of them were analyzed by MTS assay for in vitro anticancer activity in five human cancer cell ***-activity relationship for 12 ingenane-type diterpenoids in colorectal cancer Colo205 cells were preliminary *** anti-proliferation activities were observed in human melanoma cells breast cancer MDA-MB-435 cells and Colo205 *** than half of the isolated ingenane-type diterpenoids showed inhibitory activities in MDA-MB-435 *** ingenane-and one jatrophane-type diterpenoids possessed much lower IC_(50) values in MDA-MB-435 cells than positive control *** structure-activity relationship analysis showed that substituent on position 20 was important for the activity of ingenane-type diterpenoids in Colo205 cells and substituent on position 3 contributed more significant biological activity of the compounds than that on position 5 in both MDA-MB-435 and Colo205 cells.

关键词： Terpenoids Anti-proliferation activity Human cancer cells Structure-activity relationship

Stellar Abundance and Galactic Chemical Evolution through LAMOST Spectroscopic Survey

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Chinese Journal of Astronomy and Astrophysics 2006年第3期6卷 265-280页

作者： Gang Zhao Yu-Qin Chen Jian-Rong Shi Yan-Chun Liang jin-Liang hou Li Chen Hua-Wei Zhang Ai-Gen Li National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 Department of Astronomy School of Physics Peking University Beijing 100871 Department of Physics and Astronomy University of Missouri Columbia MO 65211 USA

A project of a spectroscopic survey of Galactic structure and evolution with a Large sky Area Multi-Object fiber Spectroscopic Telescope （LAMOST） is presented. The spectroscopic survey consists of two observational modes for various targets in our Galaxy. One is a major survey of the Milky Way aimed at a systematic study of the stellar abundance and Galactic chemical evolution through low resolution （R = 1000 2000） spectroscopy. Another is a follow-up observation with medium resolution （R = 10000） spectrographs aimed at detailed studies of the selected stars with different chemical composition, kinematics and dynamics.

关键词： techniques: spectroscopic - stars: abundances - Galaxy: structure - Galaxy:abundances - Galaxy: kinematics and dynamics - Galaxy: evolution

Small RNA existed in commercial reverse transcriptase： primary evidence of functional small RNAs

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Protein & Cell 2015年第1期6卷 1-5页

作者： Jie Xu Xi Chen Donghai Li Qun Chen Zhen Zhou Dongxia hou jin Wang Qipeng Zhang Ke Zen Chen-Yu Zhang Jiangsu Engineering Research Center for microRNA Biology and Biotechnology State Key Laboratory of Pharmaceutical Biotechnology School of Life Sciences Nanjing University Nanjing 210093 China

SMALL RNA IN REVERSE TRANSCRIPTASE： TOO SMALL TO BE FOUND Significant background in no-template or no-primer RT-PCR is frequently noted. However, the underlying mechanism is still unclear. In this issue, Jie Xu and colleagues reveal that the com- mercial reverse transcriptases contain small RNAs. In AMV reverse transcriptase, they detected microRNAs derived from the virus host chick or other birds. This surprising finding at least partially explains the high background in some AMV reverse transcriptases based RT-PCR.

关键词： Reverse Transcriptase Small RNAs miRNA Profile miRNA Expression Profile Solexa Sequencing

Characterization,expression dynamics,and potential function of OPA1 for regulation of mitochondrial morphology during spermiogenesis in Phascolosoma esculenta

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Journal of Oceanology and Limnology 2024年第1期42卷 187-200页

作者： Xinming GAO Binbin FENG Chen DU Congcong hou Shan jin Daojun TANG Junquan ZHU Key Laboratory of Applied Marine Biotechnology by the Ministry of Education and Key Laboratory of Marine Biotechnology of Zhejiang Province School of Marine SciencesNingbo UniversityNingbo 315211China College of Ecology Lishui UniversityLishui 323000China

Mitochondria undergo morphological changes during spermatogenesis in some *** mechanism and role of mitochondrial morphology regulation,however,remain somewhat *** this study,we analyzed the molecular characteristics,expression dynamics and subcellular localization of optic atrophy protein 1(OPA1),a mitochondrial fusion and cristae maintenance-related protein,to reveal the possible regulatory mechanisms underlying mitochondrial morphology in Phascolosoma esculenta *** full-length cDNA of the *** opa1 gene(Pe-opa1)is 3743 bp in length and encodes 975 amino *** Pe-OPA1 protein is highly conservative and includes a transmembrane domain,a GTPase domain,two helical bundle domains,and a lipid-interacting *** and protein expression was higher in the coelomic fluid(a site of spermatid development)of male *** and increased first and then decreased from March to ***,their expression during the breeding stage was significantly higher than during the non-breeding stage,suggesting that Pe-OPA1 is involved in *** *** Pe-OPA1 protein was more abundant in components consisting of many spermatids than in components without,indicating that Pe-OPA1 mainly plays a role in the spermatid in coelomic ***,Pe-OPA1 was mainly detected in the spermatid *** experiments showed that the Pe-OPA1 are constitutively expressed and co-localized with mitochondria during spermiogenesis,suggesting its involvement in *** *** results provide evidence for Pe-OPA1's involvement in the regulation of mitochondrial morphology during spermiogenesis.

关键词： optic atrophy protein 1(OPA1) spermiogenesis Phascolosoma esculenta mitochondrial dynamics spermatid