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RESEARCH ON STABILITY OF OPEN BOTTOM STORAGE PLATFORM

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Journal of Hydrodynamics 1999年第2期11卷 14-19页

作者： Qi Xin-yuan jin chen-yi chen Wei-qi chen Juan-fang(China Ship Scientific Research Center, Wuxi 214082, P. R. China) China Ship Scientific Research Cent Wuxi China

In this paper, we present a new type of offshore structure, open bottomstorage platform, and its theoretical and experimental studies of its stability. In order tooptimize the design of column length and storage tank of the open bottom storage platform, we discuss the effect of air chamber length and storage on the stability of open bottom storage platform.

关键词： ocean engineering open bottom storage platform stability

Wedelolactone attenuates sepsis-associated acute liver injury by regulating the macrophage M1/M2 polarization balance through the PI3K/AKT/NF-κB signalling pathway

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Traditional Medicine Research 2024年第11期9卷 1-11页

作者： Wang-Ting Li jin-yi chen Shao-Jie Huang Dong-Mei Hu Xing-Ru Tao Fei Mu jing-yi Zhao Chao Guo Jia-Lin Duan jing-Wen Wang Department of Pharmacology Shaanxi University of Chinese MedicineXianyang 712046China Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’an 710032China Institute of Medical Research Northwestern Polytechnical UniversityXi’an 710032China.

Background:Liver injury caused by sepsis seriously impairs the normal physiology of the ***(WED)has an obvious anti-inflammatory effect against liver damage caused by various ***,further research is needed to determine if WED might mitigate acute liver damage linked to sepsis by influencing macrophage ***:We first assessed the effect of WED on lipopolysaccharides-triggered liver injury by biochemistry assay and tissue *** factors were assessed using the ELISA *** expression of Cluster of Differentiation 86(CD86)and Cluster of Differentiation 206(CD206)was measured by immunofluorescence *** protein levels of inducible nitric oxide sythase(iNOS),Arginase 1(Arg-1),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),PI3K phosphorylation(p-PI3K),AKT phosphorylation(p-AKT),inhibitor of kappa B kinase(IKK),inhibitor of kappa B(IκB),and nuclear factor kappa-B(NF-κB)p65 were quantified by western blot ***:WED decreased the level of alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP)and malondialdehyde,and increased the activity of superoxide dismutase(SOD)and glutathione peroxidase(GSH-PX).Moreover,WED exerted effective anti-inflammatory effects by decreasing the level of Tumor necrosis factor-α(TNF-α)and Interleukin 6(IL-6)and increasing the level of Interleukin 10(IL-10)in serum and *** not only decreased CD86 and iNOS expression but also increased CD206 and Arg-1 *** also downregulated the increased expression of PI3K,AKT,p-PI3K,p-AKT,IKK,and NF-κB p65 induced by lipopolysaccharides,while up-regulated the decreased expression of Iκ***,LY294002 with WED decreased the expression of protein PI3K,AKT,p-PI3K,p-AKT,IKK and NF-κB p65,and raised the expression of IκBα.Conclusion:Wedelolactone could attenuate sepsis-associated acute liver injury,and its mechanism may be associated with balancing pro-inflammatory and anti-inflamm

关键词： Wedelactone sepsis liver injury macrophage polarization PI3K/AKT/NF-κB

Antithrombin Ⅲ deficiency in a patient with recurrent venous thromboembolism:A case report

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World Journal of Clinical Cases 2023年第20期11卷 4956-4960页

作者： Jia-Qing Luo Shuai-Shuai Mao jin-yi chen Xue-ying Ke Yue-Feng Zhu Wei Huang Hai-Ming Sun Zhen-Jie Liu Department of Vascular Surgery Changxing People's HospitalChangxing 313100Zhejiang ProvinceChina Department of Endocrinology Changxing People's HospitalChangxing 313100Zhejiang ProvinceChina Department of Vascular Surgery The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Vascular Surgery Sir Runrun Shaw Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of General Surgery Changxing People's HospitalChangxing 313100Zhejiang ProvinceChina

BACKGROUND Antithrombin Ⅲ(AT3)deficiency,an autosomal dominant disease,increases the likelihood of an individual developing venous thromboembolism(VTE).Longterm anticoagulation treatment is required for those suffering from AT3 *** SUMMARY A man aged 23,who had a history of deep venous thrombosis(DVT),experienced recurrent pain and swelling in his right lower extremity for three days following withdrawal of *** was diagnosed with DVT and antithrombin Ⅲ deficiency as genetic testing revealed a single nucleotide variant in SERPINC1(c.667T>C,p.S223P).The patient was advised to accept long-term anticoagulant *** Inherited AT3 deficiency due to SERPINC1 mutations results in recurrent *** may benefit from long-term anticoagulant therapy.

关键词： Antithrombin Venous thrombosis SERPINC1 Single nucleotide variant Anticoagulant therapy Case report

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欧普艺术在现代服装设计中的应用

丝绸 2010年第2期47卷 38-42页

作者：金晨怡温州大学美术与设计学院浙江温州325035

欧普艺术在现代服装设计中受各种艺术思潮尤其是后现代主义艺术思潮的影响,其运用已经突破了传统的审美观点与美学原则,呈现出纷繁复杂的风格与形式。通过介绍欧普艺术风格与服装历史,分析了欧普艺术风格设计文化构成与市场需求,并根据... 详细信息

欧普艺术在现代服装设计中受各种艺术思潮尤其是后现代主义艺术思潮的影响,其运用已经突破了传统的审美观点与美学原则,呈现出纷繁复杂的风格与形式。通过介绍欧普艺术风格与服装历史,分析了欧普艺术风格设计文化构成与市场需求,并根据面料与服装设计的实践,提出利用错视原理和欧普艺术中特殊效果的线条修饰体形,以更接近今天的标准美。

关键词：欧普艺术后现代主义艺术服装与面料设计新美学实践修饰体形

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广东汉族民间服饰探析

丝绸 2009年第9期46卷 49-51页

作者：陈金怡苏州大学纺织与服装工程学院江苏苏州215021 华南农业大学艺术学院广州510642

分别从广东客家、广府、福佬三大汉族民系体现的文化特征、服饰特征、审美特征角度出发,结合具体的服装样式,分析其形成的因素,对广东汉族民间服饰进行了研究。

关键词：客家广府福佬民间服饰服饰特征广东

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客家服饰之“俭”及其对现代设计的启示

丝绸 2009年第3期46卷 19-21页

作者：陈金怡苏州大学材料工程学院江苏苏州215021 华南农业大学艺术学院广州510642

通过论述客家服饰"俭"的四方面表现,得出对现代设计的重要启示:生态设计的关注,理性设计的提倡,简约设计的推崇,现代设计中的应用。客家服饰之"俭"对快节奏的现代社会来说,具有一定的现实意义。研究客家服饰之"俭"对现代设计的的启示,... 详细信息

通过论述客家服饰"俭"的四方面表现,得出对现代设计的重要启示:生态设计的关注,理性设计的提倡,简约设计的推崇,现代设计中的应用。客家服饰之"俭"对快节奏的现代社会来说,具有一定的现实意义。研究客家服饰之"俭"对现代设计的的启示,使人们能够对现代设计进行审视与反思,从而使设计理念得到进一步的升华。

关键词：客家服饰客家文化节俭现代设计

Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

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Traditional Medicine Research 2025年第2期10卷 55-64页

作者： jin-Fang Wu yi-Sheng chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity

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论客家服饰的边缘审美

丝绸 2005年第8期42卷 49-51页

作者：金惠陈金怡华南农业大学艺术设计学院广东广州510642

通过客家服饰与中原服饰、当地服饰的差异性、延续性和融合性三个方面分析来论述客家服饰的边缘审美。

关键词：客家服饰中原服饰服饰文化边缘审美

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不同电压等级的四回线的纵联差动保护方案

电力系统保护与控制 2011年第18期39卷 72-79页

作者：陈金熠范春菊刘玲上海交通大学电气工程系上海200240 江西省电力设计院江西南昌330006

为克服传统纵联差动保护运用在不同电压等级的同杆四回线中容易受到耦合电感的影响,提出了基于反序负序差电流的纵联差动保护方案。不同电压等级的四回线由两个不同电压的等级的同杆双回线构成。对于同杆双回线路,当线路参数完全对称时... 详细信息

为克服传统纵联差动保护运用在不同电压等级的同杆四回线中容易受到耦合电感的影响,提出了基于反序负序差电流的纵联差动保护方案。不同电压等级的四回线由两个不同电压的等级的同杆双回线构成。对于同杆双回线路,当线路参数完全对称时,系统正常运行或是外部故障时,反向电流分量为零;而当双回线内部故障时,反向环流量存在于双回线的内部,双回线两侧反向电流之和比较大,可以构成基于反向环流量的纵联差动保护。该保护方案不仅可以避开电容电流对于差动保护的影响,而且有较强的抗过渡电阻能力。将该保护方案应用到不同电压等级的四回线的主保护中,保护性能优越,不仅可以可靠动作,还避免了电容电流对保护性能的影响。理论分析和EMTP仿真验证了基于反向分量电流的纵差保护的有效性,保护动作的可靠性。

关键词：同杆四回线反序环流量分相电流差动保护不同电压等级 EMTP仿真