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Calculation of the Physical and Microdosimetric Parameters of Electron and Alpha-Particle Radiation Using Monte Carlo Simulations

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Chinese Physics Letters 2014年第3期31卷 181-183页

作者： GENG jin-Peng CAO Tian-Guang LI Duo-Fang AN Hai-Long HAN Ying-Rong LI jin HU jin-shan LI Nan-Nan ZHAN Yong Institute of Biophysics School of Sciences Hebei University of Technology Tianjin 300401

Various ionizing radiations, such as electrons and alpha particles, transfer their energy to media by produced secondary electrons and induce double- or single-strand break of DNA, which result in variable effects. To understand how the ionizing radiations interact with DNA and break it, several models have been developed, most of them consider the water as a vapor state. Actually, the ionizing particles interact with DNA which is solved in liquid water. To compare the difference of vapor and liquid water models, we calculate the stopping power, continuous slowing down approximation （CSDA） range and S value of electrons and alpha particles at cellular scale in liquid and vapor by Monte Carlo simulations, respectively. Our data show that the stopping power and CSDA range are different in liquid and vapor water in a special energy range. For many S values, the liquid model is better than the vapor model when the energy of the electrons is higher than 100 keV and the vapor model is higher than the liquid model for the 1 MeV alpha particles.

关键词： DNA

First record of the ferret-badger Melogale cucphuongensis Nadler et al., 2011(Carnivora:Mustelidae), with description of a new subspecies, in southeastern China

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Zoological Research 2019年第6期40卷 575-579页

作者： Song Li Guo-Hua Yu Shuo Liu Chang-shan jin Kunming Natural History Museum of Zoology Kunming Institute of ZoologyChinese Academy of SciencesKunming Yunnan 650223China Research Monitoring Center Wuyishan National ParkWuyishan Fujian 354300China Fujian Wuyishan Forest Ecosystem Research Station Wuyishan Fujian 354300China

DEAR EDITOR,The ferret-badger Melogale cucphuongensis was first described from Cuc Phuong National Park in Vietnam, with no subsequent reports in later years. During our surveys of the Wuyishan Mountains of Fujian Province in southeastern China during May 2018, a Melogale specimen was identified. Analysis based on pelage and skull characteristics as well as molecular data indicated it to be a new subspecies, which we nominated as Melogale cucphuongensis guadunensis subsp. nov. This is the first record of the species in China. Therefore, this research not only expands the distribution range of the species beyond Vietnam, but also indicates that geographic variation of the species should have been proceeding in southeastern China.

关键词： ferret-badger Melogale southeastern

A novel perylene diimide-based ionene polymer and its mixed cathode interlayer strategy for efficient and stable inverted perovskite solar cells

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Journal of Energy Chemistry 2023年第7期82卷 334-342,I0008页

作者： Daizhe Wang Cong Kang Tengling Ye Dongqing He shan jin Xiaoru Zhang Xiaochen Sun Yong Zhang Department of Applied Chemistry School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001HeilongjiangChina CAS Key Laboratory of Renewable Energy Guangzhou Institute of Energy ConversionGuangzhou 510640GuangdongChina School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001HeilongjiangChina Institute of Advanced Technology Heilongjiang Academy of SciencesHarbin 150020HeilongjiangChina

Inverted(p-i-n)perovskite solar cells(PerSCs)have attracted much attention owing to their low temperature processability,less hysteresis effect and easy integration as a subunit for the tandem *** unsatisfactory interface contacts and energy level barrier between adjacent interlayers on the cathode side are one of the key challenges for the development of p-i-n ***,perylene diimidebased(PDI)ionene polymer was synthesized and developed as a cathode interlayer(CIL)to enhance interface contact,reduce the energy level barrier and prevent the migration of *** compact PNPDI CIL with high conductivity and appropriate lowest unoccupied molecular orbital(LUMO)level,resulted in a high efficiency device(20.03%),which is higher than the control device with bathophenanthroline(Bphen)(19.48%).Bphen-based CIL shows better adjusting ability of the work function of cathode metal but exhibits poor film-forming ***,the synergistic effect of 1+1>2 can be obtained by combining Bphen and PNPDI into one *** expected,the device performance was further improved by using the mixed CIL of Bphen and PNPDI,and 21.46%power conversion efficiency(PCE)was ***’s more,the compact and hydrophobic mixed CIL dramatically enhanced the resistance to I-ions and moisture,which led to much enhanced device stability.

关键词： Perylene diimide-based polymer Ionene Perovskite solar cells Interface engineeringCathode interlayer

Elasto-plastic Analysis of Circular Tunnels in Jointed Rock Masses Satisfy the Hoek-Brown Failure Criterion

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Journal of China University of Mining and Technology 2007年第3期17卷 393-398页

作者： SUN jin-shan LU Wen-bo ZHU Qi-hu CHEN Ming State Key Laboratory of Water Resource and Hydropower Engineering Science Wuhan University Wuhan Hubei 430072 China

The relationship between the Hoek-Brown parameters and the mechanical response of circular tunnels is il-lustrated. Closed-form and approximate solutions are given for the extent of the plastic zone and the stress and dis-placement fields under axisymmetrical and asymmetric stress conditions. For the same rock masses and under axisym-metrical stress conditions,the radius of the plastic zone in terms of Hoek-Brown criterion is generally an approximation of the radius in terms of the Mohr-Coulomb criterion. The radius in terms of the Hoek-Brown criterion is larger under low stress conditions. For poor quality rock masses (GSI<25),measures (such as grouting,setting rock bolts,etc.) that improve the GSI of rock masses are effective in improving the stability of tunnels. It is not advisable to improve the sta-bility of the tunnels by providing a small support resistance p through shotcrete,except for very poor quality jointed rock masses. Without reference to the quality of the rock mass,the disturbance factor D should not less than 0.5. Meas-ures which disturb rock masses during tunnel construction should be taken carefully when the tunnel depth increases.

关键词： jointed rock masses circular tunnel general Hoek-Brown failure criterion elasto-plastic analysis con-struction measures

Electronic Structure and Optical Properties of Layered Ternary Carbide Ti3AIC2

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Chinese Physics Letters 2011年第3期28卷 180-183页

作者： JIANG Jiu-Xing jin shan WANG Zhen-Hua TAN Chang-Long Department of Applied Physics Harbin University of Science and TechnologyHarbin 150080 School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001

The electronic structure and optical properties of the layered ternary compound Ti_(3)AlC_(2)are studied by the planewave psedudopotential method within the generalized gradient *** results show that Ti_(3)AlC_(2)is an electronic *** total density of states at the Fermi level mainly originates from Ti d ***,it is found that the reflectivity is nonselective in the visible *** particular,the reflectivity is high in the ultraviolet region,indicating that Ti_(3)AlC_(2)can be a promising candidate for use as an anti-ultraviolet ray coating ***,the mechanism of the optical properties is investigated on the basis of the electronic structure.

关键词： structure coating ultraviolet

A New Approach to Development of Composite Web Services

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Wuhan University Journal of Natural Sciences 2006年第1期11卷 211-216页

作者： YANG Yan-ping TAN Qing-ping YU jin-shan LIU Feng College of Computer National University of Defense Technology Changsha 410073 Hunan China

With the requirement for complex Web Services steadily increasing, there is a growing interest for reusing basic, existing Web Services to composite new ones. We present a composite Web Services development approach driven by model driven architecture （MDA） ,using UML（Unified Modeling Language） class diagram to model structure HM （Plateform Independent Platform） and UML activity diagram to model behavior PIM, then by model transformation converting the PIMs to specific Web Services specification platforms and execution platform to get the corresponding PSMs （platform specific models）. The main contributions of this paper are the all-around solution to Web Services composition development and the transformation rules for structure and behavior model of Web Services between PIMs and PSMs.

关键词： Web service composition MDA model transformation UML

Evolution of microstructure and hardness in a dual-phase Al0.5CoCrFeNi high-entropy alloy with different grain sizes

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Rare Metals 2020年第2期39卷 156-161页

作者： Hao-Xue Yang jin-shan Li Tong Guo William-Yi Wang Hong-Chao Kou Jun Wang State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an710072China

Cold-rolling with subsequent annealing was carried out to produce recrystallized structures with different grain sizes in an Al0.5CoCrFeNi high-entropy alloy to systematically investigate the grain growth behavior and varying *** results show that recrystallized microstructures can be achieved through an annealing process at 1200℃for 75 min to 16 h,and the average grain size in this study ranges from 5.33 to 30.03 μ*** hardness shown to be affected through grain coarsening was then measured as a function of the grain size,and it is found to follow the classical Hall-Petch strengthening.

关键词： High-entropy alloy Grain growth Recrystallization Grain boundary Hall-Petch effect

Characterization,expression dynamics,and potential function of OPA1 for regulation of mitochondrial morphology during spermiogenesis in Phascolosoma esculenta

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Journal of Oceanology and Limnology 2024年第1期42卷 187-200页

作者： Xinming GAO Binbin FENG Chen DU Congcong HOU shan jin Daojun TANG Junquan ZHU Key Laboratory of Applied Marine Biotechnology by the Ministry of Education and Key Laboratory of Marine Biotechnology of Zhejiang Province School of Marine SciencesNingbo UniversityNingbo 315211China College of Ecology Lishui UniversityLishui 323000China

Mitochondria undergo morphological changes during spermatogenesis in some *** mechanism and role of mitochondrial morphology regulation,however,remain somewhat *** this study,we analyzed the molecular characteristics,expression dynamics and subcellular localization of optic atrophy protein 1(OPA1),a mitochondrial fusion and cristae maintenance-related protein,to reveal the possible regulatory mechanisms underlying mitochondrial morphology in Phascolosoma esculenta *** full-length cDNA of the *** opa1 gene(Pe-opa1)is 3743 bp in length and encodes 975 amino *** Pe-OPA1 protein is highly conservative and includes a transmembrane domain,a GTPase domain,two helical bundle domains,and a lipid-interacting *** and protein expression was higher in the coelomic fluid(a site of spermatid development)of male *** and increased first and then decreased from March to ***,their expression during the breeding stage was significantly higher than during the non-breeding stage,suggesting that Pe-OPA1 is involved in *** *** Pe-OPA1 protein was more abundant in components consisting of many spermatids than in components without,indicating that Pe-OPA1 mainly plays a role in the spermatid in coelomic ***,Pe-OPA1 was mainly detected in the spermatid *** experiments showed that the Pe-OPA1 are constitutively expressed and co-localized with mitochondria during spermiogenesis,suggesting its involvement in *** *** results provide evidence for Pe-OPA1's involvement in the regulation of mitochondrial morphology during spermiogenesis.

关键词： optic atrophy protein 1(OPA1) spermiogenesis Phascolosoma esculenta mitochondrial dynamics spermatid

Proteomics Study of Benzene Metabolite Hydroquinone Induced Hematotoxicity in K562 Cells

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Biomedical and Environmental Sciences 2024年第4期37卷 341-353页

作者： jin Yi shan YI Zong Chun ZHANG Yu jing RONG Long YU Chun Hong School of Biological Science and Medical Engineering Beihang UniversityBeijing 100191China School of Engineering Medicine Beihang UniversityBeijing 100191China

Objective Hydroquinone(HQ),one of the phenolic metabolites of benzene,is widely recognized as an important participant in benzene-induced ***,there are few relevant proteomics in HQ-induced hematotoxicity and the mechanism hasn’t been fully understood *** In this study,we treated K562 cells with 40μmol/L HQ for 72 h,examined and validated protein expression changes by Label-free proteomic analysis and Parallel reaction monitoring(PRM),and performed bioinformatics analysis to identify interaction *** One hundred and eighty-seven upregulated differentially expressed proteins(DEPs)and 279 downregulated DEPs were identified in HQ-exposed K562 cells,which were involved in neutrophilmediated immunity,blood microparticle,and other GO terms,as well as the lysosome,metabolic,cell cycle,and cellular senescence-related *** on the 23 DEGs and 5 DEPs in erythroid differentiation-related pathways,we constructed the network of protein interactions and determined 6 DEPs(STAT1,STAT3,CASP3,KIT,STAT5B,and VEGFA)as main hub proteins with the most interactions,among which STATs made a central impact and may be potential biomarkers of HQ-induced *** Our work reinforced the use of proteomics and bioinformatic approaches to advance knowledge on molecular mechanisms of HQ-induced hematotoxicity at the protein level and provide a valuable basis for further clarification.

关键词： Hydroquinone Proteomics Hematotoxicity K562 cells