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Bullous pemphigoid associated with acquired hemophilia A: A case report

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World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-Ye Hu Meng-Can Li Zi-Jia Hao Xu-Ya chai Pei-Sai Li Yang Liu Li-Xia Liu Ying Xu Pan-Pan Yang ling-E Li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (< 1.0%). Furthermore, the FⅧ inhibitor titer had greatlyincreased (59.2 Bethesda units). Therefore, the patient was diagnosed as having BP associated with AHA, prescribed 0.05% topical halometasone cream, and transferred to a higher-level hospitalfor effective treatment;however, he died after 2 *** AHA associated BP is rare, dangerous, and has a high mortality rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

Progress in developing self-consolidating concrete(SCC)constituting recycled concrete aggregates:A review

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International Journal of Minerals,Metallurgy and Materials 2021年第4期28卷 522-537页

作者： Yu-Xuan Liu Tung-chai ling Kim-Hung Mo Key Laboratory for Green&Advanced Civil Engineering Materials and Application Technology of Hunan Province College of Civil EngineeringHunan UniversityChangsha 410082China Department of Civil Engineering Faculty of EngineeringUniversity of MalayaMalaysia

Recycled concrete aggregate(RCA)derived from demolition waste has been widely explored for use in civil engineering *** of the promising strategies globally is to incorporate RCA into concrete ***,the use of RCA in high-performance concrete,such as self-consolidating concrete(SCC),has only been studied in the past *** paper summarizes recent publications on the use of coarse and/or fine RCA in *** expected,the high-water absorption and porous structure of RCA have posed challenges in producing a high-fluidity *** to an analysis of published data,a lower strength reduction(within 23%regardless of coarse RCA content)is observed in SCC compared with vibrated concrete,possibly due to the higher paste content in the SCC matrix,which enhances the weak surface layer of RCA and interfacial transition ***,SCC tends to become less durable with RCA substitution although the deterioration can be minimized by using treated RCA through removing or strengthening the adhered *** date,the information reported on the role of RCA in the long-term performance of SCC is still limited;thus,a wide range of research is needed to demonstrate the feasibility of RCA–SCC in field applications.

关键词： self-consolidating concrete construction and demolition waste recycled concrete aggregate(RCA) durability property enhancement

2009-2015年青岛市手足口病病原中柯萨奇病毒A4型VP1区基因特征分析

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中国病毒病杂志 2017年第2期7卷 124-128页

作者：史晓燕汪照国宫金伶柴青赵丹苏志磊张凤高汝钦青岛市疾病预防控制中心青岛市预防医学研究院山东青岛266033

目的阐明2009-2015年引起青岛市手足口病(hand,foot and mouth disease,HFMD)的病原之一柯萨奇病毒A4型(CV-A4)VP1编码区的基因特征。方法用荧光RT-PCR法对青岛市2009-2015年HFMD患者的咽拭子标本进行总肠道病毒(EV)、柯萨奇病毒A16(CV-... 详细信息

目的阐明2009-2015年引起青岛市手足口病(hand,foot and mouth disease,HFMD)的病原之一柯萨奇病毒A4型(CV-A4)VP1编码区的基因特征。方法用荧光RT-PCR法对青岛市2009-2015年HFMD患者的咽拭子标本进行总肠道病毒(EV)、柯萨奇病毒A16(CV-A16)型和肠道病毒71(EVA71)型检测,以半巢式反转录PCR扩增非EV-A71,非CV-A16型肠道病毒VP1区部分基因序列,结合序列分析鉴定CV-A4血清型。对全部CV-A4阳性分离株进行VP1基因全长序列扩增及基因序列测定。用MEGA 5.0软件进行遗传进化及分子特征分析。结果青岛市2009-2015年7 967份HFMD患者的咽拭子标本中共分离到CV-A4 39株,分别占各年度肠道病毒总构成比的0.18%(1/541)、0.21%(2/944)、0.29%(2/681)、1.37%(4/292)、2.25%(12/534)、0.75%(7/928)和1.86%(11/591)。遗传进化分析显示,94.87%(37/39)的青岛地区CV-A4分离株位于C2b亚型,5.13%(2/39)位于C1亚型;青岛C2b亚型病毒株VP1区核苷酸一致性为90.7%~100.0%,氨基酸一致性为96.9%~100.0%。结论 CVA4不是引起HFMD的优势病原,C2b亚型毒株是青岛市CV-A4的优势流行株,同时伴有C1亚型毒株的流行。

关键词：手足口病柯萨奇病毒A4型遗传进化分析

On the Polygonal Wear Evolution of Heavy-Haul Locomotive Wheels due to Wheel/Rail Flexibility and Its Mitigation Measures

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 40-61页

作者： Yunfan Yang Feifan chai Pengfei Liu Liang ling Kaiyun Wang Wanming Zhai State Key Laboratory of Mechanical Behavior and System Safety of Traffic Engineering Structures Shijiazhuang Tiedao UniversityShijiazhuang 050043China State Key Laboratory of Rail Transit Vehicle System Southwest Jiaotong UniversityChengdu 610031China

Wheel polygonal wear can immensely worsen wheel/rail interactions and vibration performances of the train and track,and ultimately,lead to the shortening of service life of railway *** present,wheel/rail medium-or high-frequency frictional interactions are perceived as an essential reason of the high-order polygonal wear of railway wheels,which are potentially resulted by the flexible deformations of the train/track system or other external *** this work,the effect of wheel/rail flexibility on polygonal wear evolution of heavy-haul locomotive wheels is explored with aid of the long-term wheel polygonal wear evolution simulations,in which different flexible modeling of the heavy-haul wheel/rail coupled system is ***,the mitigation measures for the polygonal wear of heavy-haul locomotive wheels are *** results point out that the evolution of polygonal wear of heavy-haul locomotive wheels can be veritably simulated with consideration of the flexible effect of both wheelset and *** of mixed-line operation of heavy-haul trains and application of multicut wheel re-profiling can effectively reduce the development of wheel polygonal *** research can provide a deep-going understanding of polygonal wear evolution mechanism of heavy-haul locomotive wheels and its mitigation measures.

关键词： Heavy-haul locomotive Wheel polygonal wear Wheel/rail flexibility Long-term polygonal wear evolution Mitigation measures

Energy Efficient Constrained Shortest Path First-Based Joint Resource Allocation and Route Selection for Multi-Hop CRNs

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China Communications 2017年第12期14卷 72-86页

作者： Qianbin Chen ling Wang Yuanpeng Gao Rong chai Xiaoge Huang Key Lab of Mobile Communication Technology Chongqing University of Posts and Telecommunications Chongqing 400065 China

Cognitive radio networks(CRNs) are expected to improve spectrum utilization efficiently by allowing secondary users(SUs) to opportunistically access the licensed spectrum of primary users(PUs).In CRNs,source and destination SUs may achieve information interaction in an ad hoc *** the case that no direct transmission link between the SU transmission pairs is available,multi-hop relay SUs can be applied to forward information for the source and destination SUs,resulting in multi-hop *** this paper,we consider a multi-hop CRN consisting of multiple PUs,SU transmission pairs and relay *** the importance of transmission hops and the tradeoff between data rate and power consumption,we propose an energy efficient constrained shortest path first(CSPF)-based joint resource allocation and route selection algorithm,which consists of two sub-algorithms,i.e.,CSPF-based route selection sub-algorithm and energy efficient resource allocation *** specifically,we first apply CSPF-based route selection sub-algorithm to obtain the shortest candidate routes(SCRs) between the SU pair under the transmission ***,an energy efficient resource allocation problem of the SCRs is formulated and solved by applying iterative algorithm and Lagrange dual ***-lation results demonstrate the effectiveness of the proposed algorithm.

关键词： cognitive radio network multi-hop relay resource allocation route selection energy efficiency

Techniques of microwave permeability characterization for thin films

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Chinese Physics B 2019年第9期28卷 37-49页

作者： Xi-ling Li Jian-Bo Wang Guo-Zhi chai Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education Lanzhou UniversityLanzhou 730000China Key Laboratory for Special Function Materials and Structural Design of the Ministry of Education Lanzhou UniversityLanzhou 730000China National Demonstration Center for Experimental Physics Education Lanzhou UniversityLanzhou 730000China

We review the microwave methods to characterize the material properties, including the established and the emerging techniques in material characterization, especially the permeability spectra of the magnetic thin *** all aspects of the microwave techniques for characterizing the permeability of thin films at microwave frequencies, including the new methods developed by our group, are ***, the introduction part is ***, the coaxial-line with transmission/reflection methods and the pickup coil with electromagnetic induction method are ***, the most widely used shorted microstrip technique is discussed in detail by the equivalent circuit method, transmission line method,and electromagnetic induction ***, the coplanar waveguide method and the near-field probe method are also ***, the high temperature permeability characterization by using the shorted microstrip line, the near-field microwave probe, and the shorted microstrip line probe are described in *** paper may be useful for researchers or engineers who will build up such measurement fixture to make full use of the existing methods or to develop original methods to meet the requirements for ever-rising measurements.

关键词： high frequency permeability coaxial-line methods induction coil method shorted microstrip technique coplanar waveguide method

Photocatalytic degradation of organic pollutants using green oil palm frond-derived carbon quantum dots/titanium dioxide as multifunctional photocatalysts under visible light radiation

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Chinese Journal of Chemical Engineering 2022年第11期51卷 21-34页

作者： Zeng Wei Heng Woon Chan Chong Yean ling Pang Lan Ching Sim chai Hoon Koo Lee Kong Chian Faculty of Engineering and Science Universiti Tunku Abdul RahmanSungai Long CampusJalan Sungai LongCheras43000 KajangSelangorMalaysia Centre for Photonics and Advanced Materials Research Universiti Tunku Abdul RahmanSungai Long CampusJalan Sungai LongCheras43000 KajangSelangorMalaysia

The present work suggested the use of waste oil palm frond as an alternative precursor for nitrogendoped carbon quantum dots(NCQDs)and proposed a straightforward in-situ hydrothermal method for the preparation of NCQDs/TiO_(2)*** elemental composition,morphological,structural and optical characteristics of NCQDs/TiO_(2)nanocomposites have been comprehensively *** successful grafting of NCQDs on TiO_(2)matrix was confirmed by the formation of Ti AOAC bond and the electronic coupling between theπ-states of NCQDs and the conduction band of TiO_(2).For the first time,the oil palm frond-derived NCQDs/TiO_(2)was adopted in the photodegradation of methylene blue(MB)under visible-light *** a result,the photocatalytic efficiency of NCQDs/TiO_(2)nanocomposites(86.16%)was 2.85 times higher than its counterpart TiO_(2)(30.18%).The enhanced performance of nanocomposites was attributed to the pivotal roles of NCQDs serving as electron mediator and visiblelight ***,the optimal NCQDs loading was determined at 4 ml while the removal efficiency of NCQDs/TiO_(2)-4 was the highest at a catalyst dosage of 1 g.L^(-1)under alkaline *** research work is important as it proposed a new insight to the preparation of biomass-based NCQDs/TiO_(2)using a facile synthetic method,which offers a green and sustainable water remediation technology.

关键词： Oil palm frond biomass N-doped carbon quantum dots Titanium-dioxide In-situ hydrothermal Visible light photocatalysis Methylene blue

Identification of Gesture Based on Combination of Raw sEMG and sEMG Envelope Using Supervised Learning and Univariate Feature Selection

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Journal of Bionic Engineering 2019年第4期16卷 647-662页

作者： Shili Liang Yansheng Wu Jianfei Chen ling Zhang Peipei Chen Zongqian chai Chunlei Cao School of Physics Northeast Normal UniversityChangchun 130022China College of Science Changchun University of Science and TechnologyChangchun 130022China

In this paper,we propose a novel study for gesture identification using surface electromyography(sEMG)signal,and the raw sEMG signal and the sEMG envelope signal are collected by the sensor at the same *** efficient method of gesture identification based on the combination of two signals using supervised learning and univariate feature selection is *** previous research techniques,researchers tend to use the raw sEMG signal and extract several constant features for classification,which inevitably causes a result of ignoring individual *** experiment shows that both the optimal feature set and redundant feature set are not same for different *** order to address this problem,we extract all the common features from two signals,up to 76 features,most of which has been established as the common EMG-based gesture *** addition,extracting too many features in an application can reduce operational efficiency,so we apply for feature selection to get the optimal feature set and decrease the number of extracting *** a result,the combination of two signals is better than using a single *** feature selection can be used to select optimal feature set from all features to achieve the best classification performance for each *** experimental results demonstrate that the proposed method achieves the performance with the highest accuracy of 95%for identifying up to nine gestures only using two ***,we develop a real-time intelligent sEMG-driven bionic hand system by using the proposed method.

关键词： gesture identification surface electromyography(sEMG) supervised learning univariate feature selection individual differences

Factors influencing Frey syndrome after parotidectomy with acellular dermal matrix

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World Journal of Clinical Cases 2024年第9期12卷 1578-1584页

作者： Xian-Da chai Huan Jiang ling-ling Tang jing Zhang Long-Fei Yue Department of Oral and Maxillofacial Surgery People’s Hospital of AnshunAnshun 561000Guizhou ProvinceChina Department of General Practice People’s Hospital of AnshunAnshun 561000Guizhou ProvinceChina

BACKGROUND Frey syndrome,also known as ototemporal nerve syndrome or gustatory sweating syndrome,is one of the most common complications of parotid gland *** condition is characterized by abnormal sensations in the facial skin accompanied by episodes of flushing and sweating triggered by cognitive processes,visual stimuli,or *** To investigate the preventive effect of acellular dermal matrix(ADM)on Frey syndrome after parotid tumor resection and analyzed the effects of Frey syndrome across various surgical methods and other factors involved in parotid tumor *** Retrospective data from 82 patients were analyzed to assess the correlation between sex,age,resection sample size,operation time,operation mode,ADM usage,and occurrence of postoperative Frey *** Among the 82 patients,the incidence of Frey syndrome was 56.1%.There were no significant differences in sex,age,or operation time between the two groups(P>0.05).However,there was a significant difference between ADM implantation and occurrence of Frey syndrome(P<0.05).ADM application could reduce the variation in the incidence of Frey syndrome across different operation *** ADM can effectively prevent Frey syndrome and delay its onset.

关键词： Parotid gland tumor Frey syndrome Acellular dermal matrix Acellular allogenic dermal matrix