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Treatment of acute dacryocystitis by translacrimal canalicular drainage and D-silicone intubation

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1628-1632页

作者： jin-jing He jing-Wen Gong Jia-Ni Zhou jin jiang Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s Hospital(Affiliated People’s Hospital)Hangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina Xianju People’s Hospital Zhejiang Southeast Campus of Zhejiang Provincial People’s HospitalAffiliated Xianju’s HospitalHangzhou Medical CollegeTaizhou 317300Zhejiang ProvinceChina

AIM:To demonstrate the outcomes of translacrimal canalicular drainage using a lacrimal probe and intranasal drainage by D-silicone intubation for acute dacryocystitis(AD).METHODS:This retrospective study included 23 patients with AD and had undergone abscess decompression with the use of lacrimal probe and intranasal drainage by D-silicone intubation between January 2019 and December *** received abscess decompression and systemic antibiotic-corticosteroid from the time of diagnosis.D-silicone tube was inserted within 10d after diagnosis and removed 3-6mo after *** procedure and outcomes of this method were ***:All patients showed improvement of signs and symptoms of AD within *** intraoperative and postoperative complications were *** recurrence of lacrimal sac abscesses occurred after D-silicone tube ***:Lacrimal probe and D-silicone intubation appear to be a feasible,minimally invasive,safe,and effective method,which could be a reasonable choice in the treatment of AD.

关键词： acute dacryocystitis treatment translacrimal canalicular drainage D-silicone intubation

A Composite Elastomer with Photo-responsive Shape Memory and Programmable Hygroscopic Actuation Functionalities

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Chinese Journal of Polymer Science 2024年第10期42卷 1470-1478,I0009页

作者： Xiang-Xi Cui Li Shang Zhong-Wen Liu Zhao-Tie Liu jin-Qiang jiang Guo Li Key Laboratory of Syngas Conversion of Shaanxi Province School of Chemistry and Chemical EngineeringShaanxi Normal UniversityXi’an710062China

Developing hydroscopic actuators with simultaneous high elasticity,shape programmability and tunable actuating behaviors are highly desired but still *** this study,we propose an orthogonal composite design to develop such a *** developed composite elastomer comprises carboxyl group-grafted polystyrene-block-poly(ethylene-co-butylene)-block-polystyrene(SEBS-g-COOH)as the elastic substrate,and a synthesized azobenzene derivative as the functional filler(Azo12).By surface treatment using acidic and base solutions,the carboxyl groups on the surface can reversibly transform into carboxylate groups,which render the composite tunable hygroscopic actuating *** another aspect,the added filler undergoes trans-to-cis isomerization when exposed to UV light irradiation,leading to liquefaction of the crystalline aggregates formed by Azo12 *** liquefied Azo12 molecules can autonomously resotre their trans form and reform the crystalline *** reversible change in crystralline structure is utilized to realize the shape memory property,and 5 wt%of Azo12addition is adequate for the composite to exhibit photo-responsive shape memory behavior without compromising much of the *** regualtion of external geometry by shape memory effect is effective in altering the actuating *** proposed method can be extend to designing different composites with the demonstrated functionalities.

关键词： Actuator Shape memory Photo-responsive Hygroscopic responsive Azobenzene

Effect of Heat Treatment on Gradient Microstructure and Tensile Property of Laser Powder Bed Fusion Fabricated 15-5 Precipitation Hardening Stainless Steel

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 181-195页

作者： Sheng Cao Hongyu Liu jin jiang Ke He Binghua Lv Hao Zhang Lujie Zhang jingrong Meng Hao Deng Xiaodong Niu Department of Mechanical Engineering College of EngineeringShantou UniversityShantou515063China China State Shipbuilding Co. Ltd.Huangpu Wenchong Shipbuilding Company Ltd.Guangzhou510715China Faculty of Materials and Manufacturing Beijing University of TechnologyBeijing100080China Shantou Ruixiang Mould Co. Ltd.Shantou515041China Military Representative Office X of Unit 93147 Deyang618000China China National Erzhong Group Co. Deyang Wanhang Die Forging Co.Ltd.Deyang618013China

This work investigated the gradient microstructure evolution and tensile property of LPBF fabricated 15-5 precipitation hardening stainless steel in post-process direct ageing(DA)and solution treating&ageing(STA).The varied microstructures for austenite and small-sized oxide inclusions at different sample heights in the as-built(AB)condition was generally preserved after DA ***,austenite was almost disappeared,and oxide particle grew significantly after the STA *** a result,the tensile property differences in sample top and bottom for AB and DA conditions did not occur in the STA *** the influence of post-process heat treatment,the STA condition had the highest yield strength due to the highest volume fraction of nano-sized Cu ***,the DA specimen had the highest ultimate tensile strength and elongation owing to the considerable amount of austenite phase and associated transformation induced plasticity effect.

关键词： 15-5 PH stainless steel Laser powder bed fusion Heat treatment Gradient microstructures Tensile properties

Uridine diphosphate glucuronosyltransferase 1A1 prevents the progression of liver injury

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World Journal of Gastroenterology 2024年第9期30卷 1189-1212页

作者： jin-Lian jiang Yi-Yang Zhou Wei-Wei Zhong Lin-Yan Luo Si-Ying Liu Xiao-Yu Xie Mao-Yuan Mu Zhi-Gang jiang Yuan Xue Jian Zhang Yi-Huai He Department of Infectious Diseases Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Infectious Diseases Jingmen Central HospitalJingmen 448000Hubei ProvinceChina Department of Respiratory Medicine Anshun People’s HospitalAnshun 561099Guizhou ProvinceChina Department of General Practice Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Intervention Radiology Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina School of Public Health Zunyi Medical UniversityZunyi 563099Guizhou ProvinceChina Department of Liver Diseases Third People’s Hospital of ChangzhouChangzhou 213000Jiangsu ProvinceChina Department of Digestion Dafang County People’s HospitalBijie 551600Guizhou ProvinceChina

BACKGROUND Uridine diphosphate glucuronosyltransferase 1A1(UGT1A1)plays a crucial role in metabolizing and detoxifying endogenous and exogenous ***,its contribution to the progression of liver damage remains *** To determine the role and mechanism of UGT1A1 in liver damage *** We investigated the relationship between UGT1A1 expression and liver injury through clinical ***,the impact and mechanism of UGT1A1 on the progression of liver injury was analyzed through a mouse model *** Patients with UGT1A1 gene mutations showed varying degrees of liver damage,while patients with acute-onchronic liver failure(ACLF)exhibited relatively reduced levels of UGT1A1 protein in the liver as compared to patients with chronic *** suggests that low UGT1A1 levels may be associated with the progression of liver *** mouse models of liver injury induced by carbon tetrachloride(CCl_(4))and concanavalin A(ConA),the hepatic levels of UGT1A1 protein were found to be *** mice with lipopolysaccharide or liver steatosis-mediated liver-injury progression,the hepatic protein levels of UGT1A1 were decreased,which is consistent with the observations in patients with ***1A1 knockout exacerbated CCl_(4)-and ConA-induced liver injury,hepatocyte apoptosis and necroptosis in mice,intensified hepatocyte endoplasmic reticulum(ER)stress and oxidative stress,and disrupted lipid *** UGT1A1 is upregulated as a compensatory response during liver injury,and interference with this upregulation process may worsen liver ***1A1 reduces ER stress,oxidative stress,and lipid metabolism disorder,thereby mitigating hepatocyte apoptosis and necroptosis.

关键词： Uridine diphosphate glucuronosyltransferase 1A1 Liver injury progression Endoplasmic reticulum stress Oxidative stress Lipid metabolism disorders

Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1227-1235页

作者： Wen-jing Hu Gang Bai Yan Wang Dong-Mei Hong jin-Hua jiang Jia-Xun Li Yin Hua Xin-Yu Wang Ying Chen Intensive Care Unit Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China Department of Anesthesia and Perioperative Medicine Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China Department of Nursing Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China Department of Thyroid Breast and Vascular SurgeryShanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China

BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical *** To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer *** In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October *** incidence of postoperative delirium was recorded for 7 d *** were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative *** SMOTE technique was applied to enhance the model by oversampling the delirium *** model’s predictive accuracy was then *** In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative *** included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain *** incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of *** comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive *** This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of tradi

关键词： Elderly patients Abdominal cancer Postoperative delirium Synthetic minority oversampling technique Predictive modeling Surgical outcomes

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穴位刺激调控自主神经系统的区域异质性

World Journal of Acupuncture-Moxibustion 2024年第2期34卷 77-82页

作者：姜劲峰南京中医药大学教育部针药结合重点实验室南京210023

Acupoints on the different parts of the body surface vary in regulating the autonomic nervous system(ANS),exhibiting differences in the acupoint specificity in terms of the distributing directions of sympathetic and parasympathetic *** paper introduces the rules of acupoints on the corresponding body surfaces in modulating ANS based on their location at four limbs,abdomen,sacrum,head and face,suboccipital and lateral cervical region and auricle(concha).The fundamental rule of acupoint heterogeneity in ANS regulation is that:all acupoints can induce somatic-sympathetic *** regional heterogeneity of acupoints in ANS is shown:by the fact that stimulation beyond a certain intensity can induce systemic autonomic *** acupoints on the abdomen act on the sympathetic nervous system,those at concha on the vagal system and those on the sacral region on the sacral parasymathetic *** heterogeneity of acupoints in regulating ANS refers to co-effects of acupoints specific effect(within segments) and its systemic effect(whole body),which embodies the specificity of acupoints *** acupoints on the same body surface regions display the homogeneity of *** the heterogeneous characteristics of acupoints in modulating ANS is particularly conductive to constructing the theoretical basis of acupoints in clinical acupuncture treatment for systemic diseases.

关键词： Acupoints Acupoint specificity Autonomicnerve Vagus nerve Sympathetic nerve Sacral parasympathetic nerve

Dermatoscope for the diagnosis of erythema with purpura induced by lidocaine/prilocaine cream:A case report

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World Journal of Clinical Cases 2024年第22期12卷 5225-5228页

作者： Xiu Lin jin-Dou jiang Xue-Zhen Guo Kui-Kui Hu Department of Medical Aesthetics Guangdong Women and Children HospitalGuangzhou 511400Guangdong ProvinceChina

BACKGROUND Lidocaine/prilocaine(EMLA)cream is a local anesthetic that is applied to the skin or mucosa during painful therapeutic procedures with few reported side *** SUMMARY Here,we report the use of dermatoscopy to identify a case of erythema with purpura,a rare side effect,after the application of 5%EMLA *** We conclude that erythema with purpura is caused by irritation and toxicity associated with EMLA,but the specific mechanism by which the toxic substance affects skin blood vessels is *** response to this situation and for cosmetic needs,we recommend tranexamic acid,in addition to routine therapy,to prevent changes in pigmentation in patients with dermatitis.

关键词： Erythema Purpura Lidocaine/prilocaine Dermatoscope Toxic reaction Case report

二次碳化物特征调控及其对高碳高合金马氏体钢耐磨性的影响

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东北大学学报（自然科学版） 2024年第4期45卷 490-498页

作者：蒋金哲刘越刘春明东北大学材料科学与工程学院辽宁沈阳110819

二次碳化物的尺寸、含量对高碳高合金马氏体钢的力学性能及耐磨性有着重要影响.本文采用扫描电子显微镜、透射电子显微镜和磨粒磨损实验等手段,研究了高碳高合金马氏体钢锻造及球化退火过程中二次碳化物的演变行为及其对高碳高合金马氏... 详细信息

二次碳化物的尺寸、含量对高碳高合金马氏体钢的力学性能及耐磨性有着重要影响.本文采用扫描电子显微镜、透射电子显微镜和磨粒磨损实验等手段,研究了高碳高合金马氏体钢锻造及球化退火过程中二次碳化物的演变行为及其对高碳高合金马氏体钢力学性能及耐磨性的影响.结果表明:球化退火显著增加了锻造空冷态实验钢中二次碳化物的含量及尺寸;在奥氏体化过程中,二次碳化物通过钉扎晶界显著细化了奥氏体晶粒,同时二次碳化物的存在降低了马氏体中合金元素固溶量,进而有效提升了实验钢的冲击韧性.高硬度的微米级二次碳化物配合高韧性马氏体基体可有效阻碍磨粒切削并减轻磨损表面的微观断裂,进而提升实验钢的耐磨性.

关键词：高碳高合金马氏体钢二次碳化物硬度冲击韧性耐磨性

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结构动载荷识别研究进展

振动工程学报 2024年第10期37卷 1625-1650页

作者：姜金辉张方南京航空航天大学航空航天结构力学及控制全国重点实验室江苏南京210016

作用于工程结构上的动载荷由于环境等限制难以通过直接测量的方式获取,基于动响应信息间接识别或重构动载荷已成为一种十分有效的途径。动载荷识别经过数十年的发展,已经形成了一系列行之有效的方法。本文总结了动载荷识别方法的研究历... 详细信息

作用于工程结构上的动载荷由于环境等限制难以通过直接测量的方式获取,基于动响应信息间接识别或重构动载荷已成为一种十分有效的途径。动载荷识别经过数十年的发展,已经形成了一系列行之有效的方法。本文总结了动载荷识别方法的研究历程及主要成果,系统性阐述了典型时、频域方法以及基于函数拟合思想、正则化策略、贝叶斯框架、数据驱动等动载荷识别方法,并讨论了各方法的优缺点以及适用范围。此外,还针对载荷识别过程中普遍存在的结构参数不确定问题以及输入条件不确定问题进行了总结。动载荷位置识别也是动载荷识别问题的重要组成部分,本文对现有位置识别方法进行了归纳分析。探讨了动载荷识别方法的工程应用,并分析了现有方法的局限性。结合当前实际工程应用中日益迫切的需求及动载荷识别领域面临的问题,展望了未来动载荷识别亟需攻克的技术难题以及可能的发展方向和重点领域。

关键词：动载荷识别数据驱动不确定性位置识别工程应用