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Migration and accumulation characteristics of natural gas hydrates in the uplifts and their slope zones in the Qiongdongnan Basin,China

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China Geology 2022年第2期5卷 234-250页

作者： Yu-lin He jin-qiang Liang Zeng-gui Kuang Wei Deng jin-feng ren Hong-fei Lai Miao-miao Meng Wei Zhang Southern Marine Science and Engineering Guangdong Laboratory Guangzhou 511458China Guangzhou Marine Geological Survey China Geological SurveyMinistry of Natural ResourcesGuangzhou 510075China National Engineering Research Center of Gas Hydrate Exploration and Development Guangzhou 511458China

Various factors controlling the accumulation of natural gas hydrates(NGHs)form various enrichment and accumulation modes through organic *** study mainly analyzes the geological and geophysical characteristics of the NGHs occurrence in the uplifts and their slope zones within the deep-water area in the Qiongdongnan(QDN)Basin(also referred to as the study area).Furthermore,it investigates the dominant governing factors and models of NGHs migration and accumulation in the study *** results are as follows.(1)The uplifts and their slope zones in the study area lie in the dominant pressure-relief direction of fluids in central hydrocarbon-rich sags in the area,which provide sufficient gas sources for the NGHs accumulation and enrichment through pathways such as gas chimneys and faults.(2)The top and flanks of gas chimneys below the bottom simulating reflectors(BSRs)show high-amplitude seismic reflections and pronounced transverse charging of free gas,indicating the occurrence of a large amount of gas accumulation at the heights of the uplifts.(3)Chimneys,faults,and high-porosity and high-permeability strata,which connect the gas hydrate temperature-pressure stability zones(GHSZs)with thermogenic gas and biogenic gas,form the main hydrate migration system.(4)The reservoir system in the study area comprises sedimentary interlayers consisting of mass transport deposits(MTDs)and *** addition,the reservoir system has developed fissure-and pore-filling types of hydrates in the *** above well-matched controlling factors of hydrate accumulation enable the uplifts and their slope zones in the study area to become the favorable targets of NGHs exploration.

关键词： Gas chimney Overpressure Migration characteristics of gas hydrates Accumulation characteristics of gas hydrates Oil and gas exploration engineering NGHs exploration trial engineering Uplifts and slope zones Qiongdongnan Basin China

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Role of microRNAs in the process of metformin treating multiple diseases

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Frigid Zone Medicine 2021年第2期1卷 69-78页

作者： Ningning Ma jing Chen jin ren Center for Drug Safety Evaluation and Research State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China University of Chinese Academy of Sciences Beijing 100049China

Metformin as the first-line treatment for type 2 diabetes mellitus has been discovered to exert beneficial effects on many diseases for nearly ten years,but its specific mechanism is still *** a new class of gene expression regulators with pleiotropic properties,microRNAs(miRNAs)participate in multiple physiological processes such as cell differentiation,proliferation,survival,and metabolism,which drive them to play a regulatory role in the occurrence,development and even treatment of various diseases.A substantial body of research has found the relationship between metformin and miRNAs,in which metformin can alter the expression profiles of miRNAs in multiple disease states and on the other hand the signal pathways involving miRNAs may contribute to the pharmacological actions of *** review summarizes the effects of metformin on miRNAs and their relationship in different diseases(like tumor,metabolic diseases,etc.),which should be of a great help for our better understanding of the mechanism of metformin for treating multiple diseases.

关键词： metformin microRNA tumor metabolic diseases

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CAEFusion: A New Convolutional Autoencoder-Based Infrared and Visible Light Image Fusion Algorithm

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Computers, Materials & Continua 2024年第8期80卷 2857-2872页

作者： Chun-Ming Wu Mei-Ling ren jin Lei Zi-Mu Jiang Key Laboratory of Modern Power System Simulation and Control&renewable Energy Technology Ministry of EducationSchool of Electrical EngineeringNortheast Electric Power UniversityJilin132012China School of Electrical Engineering Northeast Electric Power UniversityJilin132012China School of Electronic Information Engineering Bozhou UniversityBozhou236800China

To address the issues of incomplete information,blurred details,loss of details,and insufficient contrast in infrared and visible image fusion,an image fusion algorithm based on a convolutional autoencoder is *** region attention module is meant to extract the background feature map based on the distinct properties of the background feature map and the detail feature map.A multi-scale convolution attention module is suggested to enhance the communication of feature *** the same time,the feature transformation module is introduced to learn more robust feature representations,aiming to preserve the integrity of image *** study uses three available datasets from TNO,FLIR,and NIR to perform thorough quantitative and qualitative trials with five additional *** methods are assessed based on four indicators:information entropy(EN),standard deviation(SD),spatial frequency(SF),and average gradient(AG).Object detection experiments were done on the M3FD dataset to further verify the algorithm’s performance in comparison with five other *** algorithm’s accuracy was evaluated using the mean average precision at a threshold of 0.5(mAP@0.5)*** experimental findings show that CAEFusion performs well in subjective visual and objective evaluation criteria and has promising potential in downstream object detection tasks.

关键词： Image fusion deep learning auto-encoder(AE) infrared visible light

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A novel multimode process monitoring method integrating LDRSKM with Bayesian inference

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Frontiers of Information Technology & Electronic Engineering 2015年第8期16卷 617-633页

作者： Shi-jin ren Yin LIANG Xiang-jun ZHAO Mao-yun YANG National Laboratory of Industrial Control Technology Zhejiang University School of Computer Science & Technology Jiangsu Normal University

A local discriminant regularized soft k-means （LDRSKM） method with Bayesian inference is proposed for multimode process monitoring. LDRSKM extends the regularized soft k-means algorithm by exploiting the local and non-local geometric information of the data and generalized linear discriminant analysis to provide a better and more meaningful data partition. LDRSKM can perform clustering and subspace selection simultaneously, enhancing the separability of data residing in different clusters. With the data partition obtained, kernel support vector data description （KSVDD） is used to establish the monitoring statistics and control limits. Two Bayesian inference based global fault detection indicators are then developed using the local monitoring results associated with principal and residual subspaces. Based on clustering analysis, Bayesian inference and manifold learning methods, the within and cross-mode correlations, and local geometric information can be exploited to enhance monitoring performances for nonlinear and non-Gaussian processes. The effectiveness and efficiency of the proposed method are evaluated using the Tennessee Eastman benchmark process.

关键词： Multimode process monitoring Local discriminant regularized soft k-means clustering Kernel support vector datadescription Bayesian inference Tennessee Eastman process

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Interface engineering for boosting electrocatalytic performance of CoP-Co_(2)P polymorphs for all-pH hydrogen evolution reaction and alkaline overall water splitting

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Science China Materials 2022年第9期65卷 2433-2444页

作者： Lei Chen jin-Tao ren Zhong-Yong Yuan Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) National Institute for Advanced MaterialsSchool of Materials Science and EngineeringNankai UniversityTianjin 300350China

Exploring cobalt phosphide catalysts with abundant active sites and outstanding intrinsic activity for active and robust hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)is highly ***,by the fine-tuning thermal-reduction treatment of cobalt phosphonates with spherical shape,the novel carbon-wrapped CoP-Co_(2)P polymorphs are rationally *** unique hierarchical porous architecture and heterointerface of CoP-Co_(2)P not only increase active sites but also ensure intrinsic *** resultant catalyst exhibits significantly boosted HER activity in a wide pH range,for instance,a current density of 10 mA cm^(-2) at the overpotential of 81 mV in 0.5 mol L^(-1) H_(2)SO_(4),109 mV in 1.0 mol L^(-1) KOH,and 227 mV in 1.0 mol L^(-1) phosphate buffer saline,and remarkable OER activity(1.53 V@10 mA cm^(-2) in 1.0 mol L^(-1) KOH),associated with the impressive stability for each ***,serving as the bifunctional electrocatalysts in a two-electrode electrolyzer for overall water splitting,a low cell voltage of 1.60 V can deliver a current density of 10 mA cm^(-2) in 1.0 mol L^(-1) *** structural evolution process of the CoP-Co_(2)P catalyst during electrolysis is thoroughly *** work presents a new approach for designing and fabricating efficient and affordable metal phosphides for various electrochemical technologies.

关键词： cobalt phosphides polymorphs heterointerface hydrogen evolution oxygen evolution

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A New Chiral Synthesis of Naturally Occurring (-)-(S)-4-Hydroxy-2-pyrrolidinone

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Chinese Chemical Letters 1999年第9期10卷 735-736页

作者： Pei Qiang HUANG Xiao ZHENG Shi Li WANG Jian Liang YE Li ren jin(Department of Chemistry, Xiamen University, Xiamen, Fujian 361005) Department of Chemistry Xiamen University Xiamen Fujian 361005 China

A new and convenient chiral synthesis of naturally occurring (-)-(S)-4-hydroxy-2-pyrrolidinone from (S)-malic acid was reported.

关键词： (S)-malic acid (-)-(S)-4-hydroxy-2-pyrrolidinone ionic hydrogenation

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改进型气升式硝化反应器剪切特性的研究

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环境科学 2006年第6期27卷 1088-1093页

作者：金仁村郑平浙江大学环境工程系杭州310029

研究了气升式硝化反应器的剪切特性及其影响因素．结果表明，该反应器的剪切率呈现一定的空间分布．当进气流量为430～2700L·h^-1时，反应器总体剪切率为（0．702～3．13）×10^5s^-1，升流区剪切率为（1．07～31．3）×10^5s^-1，气... 详细信息

研究了气升式硝化反应器的剪切特性及其影响因素．结果表明，该反应器的剪切率呈现一定的空间分布．当进气流量为430～2700L·h^-1时，反应器总体剪切率为（0．702～3．13）×10^5s^-1，升流区剪切率为（1．07～31．3）×10^5s^-1，气液分离区剪切率为（1．12～25．0）×10^5s^-1，最大剪切率出现在升流区．操作条件和反应器结构对该反应器的剪切率均有重大影响．当进气流量控制在1300～2700L·h^-1时，升流区和气液分离区的剪切率先降低后升高．剪切率与导流筒直径呈负相关，导流筒直径从4．0cm增大到5．5cm，升流区、气液分离区及总体剪切率分别降低85．5％、82．3％、80．6％．而与混合元件数成正相关，当导流筒直径为4．0cm时，较之普通反应器，改进型反应器升流区剪切率增大6．14（N=10）和7．97（N=39）倍，气液分离区剪切率增大7．18（N=10）和9．14（N=39）倍，总体剪切率增大6．35（N=10）和8．44（N=39）倍．该反应器的局部最大剪切率与总体剪切率之比（β）为3．68～7．66，采用较大的导流筒尺寸和适宜的静态混合元件数可促进剪切率的均匀分布．

关键词：气升式硝化反应器剪切率静态混合器

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LncRNAs expression signatures of hepatocellular carcinoma revealed by microarray

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World Journal of Gastroenterology 2014年第20期20卷 6314-6321页

作者： Wu-Tao Liu Xin Lu Guang-Hua Tang jin-Jun ren Wen-Jun Liao Peng-Lei Ge Jie-Fu Huang Department of Liver Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

AIM: To analyze the expression profiles of long non-coding RNAs (lncRNAs) in hepatocellular carcinoma.

关键词： Long non-coding RNA Hepatocellular carcinoma MALAT1 Expression signature Microarray

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Poly(heptazine imide)nanocrystal for hydrogen peroxide evolution in the dark by accumulating photo-generated electrons

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Nano Research 2024年第9期17卷 8036-8044页

作者： Song Kou Shu Lian Xiaodong Xie Wei ren Yu jin Jiahui Bao Honghui Ou Guidong Yang XJTU-Oxford International Joint Laboratory for Catalysis School of Chemical Engineering and TechnologyXi’an Jiaotong UniversityXi’an 710049China Fujian-Taiwan-Hongkong-Macao Science and Technology Cooperation Base of Intelligent Pharmaceutics Institute of OceanographyCollege of Materials and Chemical EngineeringMinjiang UniversityFuzhou 350108China School of Food and Bioengineering Fujian Polytechnic Normal UniversityFuqing 350300China

Organic conjugated polymers have received extensive attention due to their unique electronic ***,there have been relatively few reports on the dark photocatalytic reactions utilizing organic conjugated ***,we report the successful synthesis of an organic conjugated polymer based on poly(heptazine imide)nanocrystals(CNNCs)for H_(2)O_(2)evolution and biomedical applications using a simple salt molten method and sonication-centrifugation *** results show that these colloid CNNCs have the characteristics of photogenerated electrons accumulation and realize dark photocatalysis with high reducibility under visible light ***,these accumulating photogenerated electrons can reduce O_(2)in darkness to produce H_(2)O_(2).In addition,cytotoxicity tests were conducted and it was found that H_(2)O_(2)produced under dark conditions could oxidize L-arginine(L-Arg)to NO,which effectively killed tumors in the *** work provides an important strategy to construct organic conjugated semiconductor nanocrystals and applying them to future energy and biomedical fields.

关键词： poly(heptazine imide) photocatalysis photogenerated electrons hydrogen peroxide evolution cancer treatment

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响应面法优化鱼腥草洗手液制备工艺的综合实验设计

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安徽化工 2024年第3期50卷 149-153页

作者：袁颐进谢宁田奇侯龙珠段小云任金玉董雄辎姚成立合肥师范学院化学与制药工程学院安徽合肥230001 黄河科技学院现代农业工程研究院河南郑州450006

在教材原有方案中添加天然抑菌成分鱼腥草提取液,提高洗手液的抑菌性能。利用Design Expert软件优化鱼腥草抑菌洗手液的制备参数,得出最佳制备工艺。抑菌性能测试结果表明,鱼腥草洗手液具有优越的抑菌效果。

关键词：鱼腥草抑菌洗手液黄酮响应面法

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