检索结果-南通市图书馆

Recent advances on study of hadrosaurid dinosaurs in Heilongjiang(Amur) River area between China and Russia

Global Geology 2011年第3期14卷 160-191页

作者： Pascal Godefroit Pascaline Lauters jimmy van itterbeeck Yuri L. Bolotsky DONG Zhiming JIN Liyong WU Wenhao Ivan Y. Bolotsky HAI Shulin YU Tingxiang Royal Belgian Institute of Natural Sciences Department of Palaeontology B -I 000 Bruxelles Belgium Afdeling Historische Geologie Katholieke Universiteit Leuven B -3000 Leuven Belgium Amur Natural History Museum Institute of Geology and Nature Exploration FEB RAS 675000 BlagoveschenskAmurskaya Oblast＇ Russia IVPP Beijing 100044 / Research Center of Paleontology and Stratigraphy Jilin University Changchun 130026 China Museum of Jilin University Changchun 130026 China Research Center for Paleontology and Stratigraphy Jilin University Changchun 130061 China The Geological Museum of Heilongjiang Harbin 150036 China

Four main dinosaur-bearing sites have been investigated in latest Cretaceous deposits from the Amur/Heilongjiang Region ： Jiayin and Wulaga in China （ Yuliangze Formation）, Blagoveschensk and Kundur in Russia （Udurchukan Formation）. More than 90% of the bones discovered in these localities belong to hollow-crested lambeosaurine hadrosaurids： Charonosaurus fiayinensis at Jiayin, Amurosaurus riabinini at Blagoveschensk, Olorotitan arharensis at Kundur, and Sahaliyania elunchunorum at Wulaga. Flat-headed hadrosaurine hadrosaurids are much less numerous, but appear well diversified as well： Kerberosaurus manakini at Blagoveschensk, Wulagasaurus dongi at Wulaga, and a new genus at Kundur. Theropods are represented by shed teeth and isolated bones; isolated scutes and teeth discovered at Kundur are tentatively attributed to nodosaurids. Palynological studies suggest that these sites are probably synchronous with the Lancian＇ vertebrate localities of western North America, which represent the youngest dinosaur faunas in this area. However, the latest Cretaceous dinosaur assemblages are completely different in the Amur/Heilongjiang region （lambeosaurines abundant, ceratopsids absent） and in western North America （ceratopsids abundant, lainbeosaurines extremely rare or absent）. This probably reflects some kind of geographical barrier between both areas by Maastrichtian time rather than strong differences in palaeoecological conditions.

关键词： Heilongjiang Province Amur Region Late Cretaceous dinosaurs Hadrosauridae palaeobiogeography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pharmacologic RNA splicing modulation: a novel mechanism to enhance neoantigen-directed anti-tumor immunity and immunotherapy response

引用

Signal Transduction and Targeted Therapy 2021年第11期6卷 3167-3168页

作者： Kerryn Elliott Jonas Nilsson jimmy van den Eynden Department of Medical Biochemistry and Cell Biology Institute of BiomedicineSahlgrenska Academy at University of GothenburgGothenburgSweden Sahlgrenska Cancer Center Department of SurgeryInstitute of Clinical SciencesUniversity of Gothenburg and Sahlgrenska University HospitalGothenburgSweden Harry Perkins Institute of Medical Research University of Western AustraliaPerthWAAustralia Department of Human Structure and Repair Anatomy and Embryology UnitGhent UniversityGhentBelgium

A recent study by Lu et al.1 suggests a novel approach to increasing responsiveness to immune checkpoint blockade (ICB) therapy. ICB is a promising form of cancer immunotherapy that aims to boost the anti-tumoral immune response. This response is primarily driven by the presentation of different types of antigens at the cancer cell membrane via the type I major histocompatibility complex (MHC I). Neoantigens are tumor-specific antigens that are small (mostly 9-mers) mutated peptides that generally result from somatic mutations. High tumor mutational burden, which results in the formation of many neoantigens, is currently one of the main biomarkers for ICB response prediction. Because ICB is only effective in a minority of patients, new therapeutic strategies are required to augment this response.

关键词： immunity immunotherapy mostly

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Superior activity of Rh1/ZnO single-atom catalyst for CO oxidation

引用

Chinese Journal of Catalysis 2019年第12期40卷 1847-1853页

作者： Bing Han Rui Lang Hailian Tang Jia Xu Xiang-Kui Gu Botao Qiao Jingyue(jimmy)Liu CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China Department of Physics Arizona State UniversityTempeArizona 85287United States Department of Chemical Engineering and Materials Science Wayne State UniversityDetroitMI 48202United States Dalian National Laboratory for Clean Energy CASDalian 116023LiaoningChina

CO oxidation is of great importance in both fundamental study and industrial *** noble metal catalysts are highly active for CO oxidation but suffer from the scarcity and high ***-atom catalysts(SACs)can maximize the metal atom ***,ZnO nanowire(ZnO-nw)supported Rh,Au,and Pt SACs were successfully developed to investigate their CO oxidation ***,it was found that Rh1/ZnO-nw showed much higher activity than the other noble metals which are usually regarded as good candidates for CO *** addition,the Rh SAC possessed high stability in high-temperature CO oxidation under simulated conditions in the presence of water and *** high activity and stability make Rh1/ZnO-nw promising for practical applications,especially in the automotive exhaust emission *** calculations indicate that the CO oxidation proceeds via the Mars-van Krevelen mechanism and the lowest barrier for the rate-limiting O2 dissociation at a surface oxygen vacancy site is a key factor in determining the observed highest activity of Rh1/ZnO-nw amongst the studied SACs.

关键词： Single-atom catalysis Carbon monoxide oxidation Rhodium Zinc oxide nanowire Density functional theory calculations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

以任务为中心的四元教学设计模式在高等教育中的应用

引用

开放学习研究 2020年第6期25卷 22-28,60页

作者：吉米·弗雷里让杰伦·范梅里恩伯尔保罗·基尔希纳安·洛克斯伯特·埃格特马可·马塞里斯周振宇(译) 盛群力(译) 荷兰马斯特里赫特大学健康、医疗与生命科学学院荷兰马斯特里赫特荷兰马斯特里赫特大学健康专业教育学院荷兰马斯特里赫特荷兰开放大学荷兰海尔伦芬兰奥卢大学芬兰奥卢比利时布鲁塞尔自由大学医学与药学学院比利时布鲁塞尔比利时鲁汶大学公共卫生和初级保健部比利时鲁汶荷兰阿姆斯特丹应用科技大学数字媒体与创意产业学院荷兰阿姆斯特丹杭州师范大学音乐学院浙江大学教育学院

基于目标的教学设计方法将学习任务分解为具体的学习目标,并规定教师在传授所有的目标内容之前,应该选择相应最佳的教学方法。这种方法适用于各种目标之间关系不太紧密的任务,但对于教授需要整合知识、技能和态度以及协调不同技能的复... 详细信息

基于目标的教学设计方法将学习任务分解为具体的学习目标,并规定教师在传授所有的目标内容之前,应该选择相应最佳的教学方法。这种方法适用于各种目标之间关系不太紧密的任务,但对于教授需要整合知识、技能和态度以及协调不同技能的复杂专业任务时,教学效果较差。对于后者来说,以整体的、实际的任务为中心设计教学更为合适。本文介绍了以任务为中心的四元教学设计模式,并通过反思应用该模式设计的三个高等教育项目的实践案例来说明其应用方式。第一个案例介绍了荷兰阿姆斯特丹应用科技大学针对移动应用开发的课程设计;第二个案例介绍了负责荷兰教师培训的艾瑟林格教育大学的教师教育专业整合信息解决问题的技能;第三个案例来自比利时鲁汶大学的全科医学教育实例。文章最后讨论了以任务为中心的教育方案实施的问题和未来发展。

关键词：四元教学设计模式综合学习以任务为中心高等教育

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：