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Significance of inferior wall ischemia in non-dominant right coronary artery anatomy

World Journal of Cardiology 2017年第3期9卷 261-267页

作者： Ali Osama Malik Oliver Abela Subodh Devabhaktuni Arhama Aftab Malik Gayle Allenback Chowdhury H Ahsan Sanjay Malhotra jimmy diep Department of Internal Medicine University of Nevada School of Medicine Department of Cardiovascular Medicine University of Nevada School of Medicine Aga Khan Univesity Medical College Office of Medical Research Universtiy of NevadaSchool of Medicine

AIM To investigate the relationship of inferior wall ischemia on myocardial perfusion imaging in patients with nondominant right coronary artery *** This was a retrospective observational analysis of consecutive patients who presented to the emergency department with primary complaint of chest *** patients who underwent single photon emission computed tomography(SPECT)myocardial perfusion imaging(MPI)were *** who showed a reversible defect on SPECT MPI and had coronary angiography during the same hospitalization was *** with prior history of coronary artery disease(CAD)including history of percutaneous coronary intervention and coronary artery bypass graft surgerys were *** positive and false positive results were identified on the basis of hemodynamically significant CAD on coronary angiography,in the same territory as identified on SPECT *** artery dominance was determined on coronary *** were divided into group 1 and group ***1 included patients with non-dominant right coronary artery(RCA)(left dominant and codominant).Group2 included patients with dominant RCA ***,baseline characteristics and positive predictive value(PPV)were analyzed for the two *** The mean age of the study cohort was 57.6 *** point seven percent of the patients were *** prevalence of self-reported diabetes mellitus,hypertension and dyslipidemia was 36%,71.9%and 53.9%respectively.A comparison of baseline characteristics between the two groups showed that patients with a non-dominant RCA were more likely to be *** inferior wall ischemia on SPECT MPI,patients in study group 2 had a significantly higher PPV,32/42(76.1%),compared to patients in group 1,in which only 3 out of the 29 patients(10.3%)had true positive results(P value<0.001 Z test).The difference remained statistically significant even when only patients with left dominant coronary system(without co-do

关键词： Myocardial perfusion imaging Single photon emission commuted tomography False positive results Coronary artery dominance Inferior wall ischemia

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Recent advances on bismuth oxyhalides for photocatalytic CO_(2)reduction

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Journal of Environmental Sciences 2024年第6期140卷 183-203页

作者： Liangpang Xu jimmy C.Yu Ying Wang Department of Chemistry The Chinese University of Hong KongShatinNew TerritoriesHong Kong 999077China

Photocatalytic conversion of CO_(2)into fuels such as CO,CH_(4),and CH_(3)OH,is a promising approach for achieving carbon *** oxyhalides(BiOX,where X=Cl,Br,and I)are appropriate photocatalysts for this purpose due to the merits of visible-light-active,efficient charge separation,and easy-to-modify crystal structure and surface *** practical applications,multiple strategies have been proposed to develop high-efficiency BiOX-based *** review summarizes the development of different approaches to prepare BiOX-based photocatalysts for efficient CO_(2)*** the review,the fundamentals of photocatalytic CO_(2)reduction are ***,several widely used modification methods for BiOX photocatalysts are systematacially discussed,including heterojunction construction,introducing oxygen vacancies(OVs),Bi-enrichment,heteroatom-doping,and morphology ***,the challenges and prospects in the design of future BiOX-based photocatalysis for efficient CO_(2)reduction are examined.

关键词： Bismuth oxyhalides Photocatalysis CO_(2)reduction Modification methods

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Why the abnormal phenomena of D-band center theory exist?A new BASED theory for surface catalysis and chemistry

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Chinese Journal of Catalysis 2024年第9期64卷 44-53页

作者： Zelong Qiao Run Jiang jimmy Yun Dapeng Cao State Key Laboratory of Organic‐Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Qingdao International Academician Park Research Institute Qingdao 266000ShandongChina School of Chemical Engineering The University of New South WalesSydneyNSW 2052Australia

Since the D-band center theory was proposed,it has been widely used in the fields of surface chemistry by almost all researchers,due to its easy understanding,convenient operation and relative ***,with the continuous development of material systems and modification strategies,researchers have gradually found that D-band center theory is usually effective for large metal particle systems,but for small metal particle systems or semiconductors,such as single atom systems,the opposite conclusion to the D-band center theory is often *** solve the issue above,here we propose a bonding and anti-bonding orbitals stable electron intensity difference(BASED)theory for surface *** newly-proposed BASED theory can not only successfully explain the abnormal phenomena of D-band center theory,but also exhibits a higher accuracy for prediction of adsorption energy and bond length of intermediates on active ***,a new phenomenon of the spin transition state in the adsorption process is observed based on the BASED theory,where the active center atom usually yields an unstable high spin transition state to enhance its adsorption capability in the adsorption process of intermediates when their distance is about 2.5Å.In short,the BASED theory can be considered as a general principle to understand catalytic mechanism of intermediates on surfaces.

关键词： Surface chemistry Surface catalysis D-band center theory Bonding orbital Anti-bonding orbital

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Net effect of air pollution controls on health risk in the Beijing-Tianjin-Hebei region during the 2022 winter Olympics and Paralympics

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Journal of Environmental Sciences 2024年第1期135卷 560-569页

作者： Changqing Lin Peter K.K.Louie Alexis K.H.Lau jimmy C.H.Fung Zibing Yuan Minghui Tao Xuguo Zhang Md.Shakhaoat Hossain Chengcai Li Xiang Qian Lao Division of Environment and Sustainability The Hong Kong University of Science and TechnologyHong KongChina Environmental Protection Department Hong Kong Government SARHong KongChina Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality The Hong Kong University of Science and TechnologyHong KongChina Department of Mathematics The Hong Kong University of Science and TechnologyHong KongChina School of Environment and Energy South China University of TechnologyGuangzhou 510006China Hubei Key Laboratory of Critical Zone Evolution School of Geography and Information EngineeringChina University of GeosciencesWuhan 430074China Department of Public Health and Informatics Jahangirnagar UniversityDhaka 1342Bangladesh Department of Atmospheric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China Jockey Club School of Public Health and Primary Care The Chinese University of Hong KongHong KongChina

Due to the non-linearity in ozone(O_(3))formation,reducing the emission of nitrogen oxides(NO_(x))may increase O_(3) *** the counteractive O_(3) response to NO_(x) reduction,overall impact of air pollution controls can be ambiguous when the assessments focus on the changes in pollutant *** this study,a risk-based method was used to gauge the net effect of air pollution controls on mortality risk in the Beijing–Tianjin–Hebei(BTH)region during the 2022 Winter Olympics and Paralympics(WOP).This mega-event presents a unique opportunity to investigate the efficacy of deep cuts in pollutant *** show that O_(3) concentrations greatly increased as nitrogen dioxide(NO_(2))concentrations decreased in the *** to the active photochemical formations,O_(3) became the dominant pollutant that affected human health during the *** the substantial O_(3) increases,the health benefits of NO_(2) reductions overwhelmed the adverse health effects of O_(3) increases in most regions of the BTH(at 81 out of 112 stations).After considering the impacts of particulate matter,the integrated health risk of air pollution mixtures declined almost everywhere in the *** results underscore the great necessity of changing the assessment paradigm of pollution control from using concentration-based methods to using risk-based *** with the carbon neutrality policy,stringent control of NO_(x)emission from combustion sources is a promising way to achieve synergistic control solutions for air pollution and climate change.

关键词： Ozone Nitrogen dioxide Health risk Carbon neutrality Mega-events

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用于治疗阿尔茨海默症的靶向载药系统设计与制备

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过程工程学报 2024年

作者：邱嘉媛陈玺叶肖倩周理龙 jimmy Yun 河北科技大学化学与制药工程学院新南威尔士大学化工学院

阿尔茨海默症(AD)是一种非常常见的进行性和破坏性中枢神经系统退行性的疾病，会对老年人的生活质量产生影响以及对老年人的生命安全造成严重危害，给家庭、社会和国家带来了巨大的经济负担。目前治疗AD的药物尚未取得较大突破和创新，... 详细信息

阿尔茨海默症(AD)是一种非常常见的进行性和破坏性中枢神经系统退行性的疾病，会对老年人的生活质量产生影响以及对老年人的生命安全造成严重危害，给家庭、社会和国家带来了巨大的经济负担。目前治疗AD的药物尚未取得较大突破和创新，面临着突破血脑屏障的挑战，且治疗方法不当可能会导致患者产生不良反应。靶向载药系统作为一种有效的治疗方式，能够显著降低血液中的药物浓度、给药频率和药物毒副作用，同时提高药物在目标部位的浓度和疗效以及药物生物利用度，还能对药物起到缓释效果。此外，靶向载药系统还有望穿透血脑屏障，提高血脑渗透率，实现脑靶向性，精准递送药物，从而为治疗AD提供了一条高效且安全的途径。本工作综述了AD的发病机制、治疗AD的辅助药物治疗的非药物治疗方法以及针对Aβ聚集、乙酰胆碱酶抑制和受体拮抗等主要药物的作用机理和副作用，并对磁性纳米颗粒、脂质体等针对治疗AD的靶向载药系统进行了简单的介绍和梳理以及总结，并指出了现在存在的问题，提出了可能的解决方案，指明未来可能发展的方向。

关键词：阿尔茨海默症血脑屏障靶向载药系统药物发病机制

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Roles of Community Pharmacists in Screening and Disseminating of Information about Non-Steroidal Anti-Inflammatory Drugs Risks: Implications for Drug Safety Assessment

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Pharmacology & Pharmacy 2024年第4期15卷 129-145页

作者： Martin Kampamba Progress Mulenga Steward Mudenda Billy Chabalenge Jenipher Zulu Tadius Chimombe Webrod Mufwambi Mashebe Innocent Ngula Audrey Hamachila jimmy Hangoma Christabel Nang’andu Hikaambo Department of Pharmacy School of Health Sciences University of Zambia Lusaka Zambia Department of Medicines Control Zambia Medicines Regulatory Authority Lusaka Zambia Department of Pharmacy School of Health Sciences Levy Mwanawasa Medical University Lusaka Zambia

Background: The increasing use of non-steroidal anti-inflammatory drugs (NSAIDs) both on prescription and over the counter raises a major global health concern because of the risks associated with their use if no proper guidance is given by the health care provider. This study assessed the roles of community pharmacists in screening and disseminating information about the risks associated with NSAID use in Zambia. Methodology: This was a national cross-sectional study in which a structured self-administered questionnaire was administered to 245 registered community pharmacists in Zambia. Stata/BE, version 15.1 (Stata Corporation, College Station, Texas, USA) and multivariate logistic regression model was used to determine factors associated with information dissemination about ADRs of NS-NSAIDs. Results: 231 of the 245 distributed questionnaires were returned giving a response rate of 94.3%. All (100%) participating community pharmacists claimed to have practiced dispensing NSAIDs. However, only 26 (11.0%) and 71 (30.8%) regularly screened for risk factor of selective COX-2 NSAIDS (SC2-NSAIDS) and non-selective NSAIDS (NS-NSAIDs) respectively. Information dissemination on adverse drug reactions (ADRs) of SC2-NSAIDS was regularly provided by only 22 (9.5%) of pharmacists while that of NS-NSAIDs was regularly provided by 49 (21.2%). In the multivariate logistic regression model, being the owner of a pharmacy (AOR: 5.4, CI: 1.84 - 16.4) was significantly associated with information dissemination about ADRs of NS-NSAIDs while an hour increase in the working hours per day (AOR: 0.9, CI: 0.64 - 0.95) was associated with less likelihood of information dissemination. Conclusion: Pharmacists working in community pharmacies in Zambia did not regularly screen and disseminate information about the risks associated with NSAID use. Therefore, pharmacists should be able to screen and monitor patients at risk and be aware of the majority of risk factors while dispensing NSAIDs to m

关键词： Community Pharmacists Non-Steroidal Anti-Inflammatory Drug Risk Screening

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Neuropsychological Profile of a Patient with Acquired Brain Damage Following Vascular Lesion of the Left Anterior Cingulate Cortex

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Neuroscience & Medicine 2024年第1期15卷 66-75页

作者： jimmy Zúñiga-Márquez Lina Borda-Camargo Diego Buitrago-Mora Lorely Guerra-Valdés Laura González Patricia Quintero-Cusgüen Nataly Gutierrez-Ávila Hospital Universitario de la Samaritana Bogotá Colombia Neuropsychological Assessment and Diagnosis Graduate Program School of Psychology Universidad San Buenaventura Bogotá Bogotá Colombia

Stroke is a physiological alteration associated with changes in blood flow that can result in sudden-onset cognitive impairment. It has a heterogenous clinical presentation with varying degrees of severity correlated with specific central nervous system zones or areas, and its prognosis is uncertain. This case study describes a 62-year-old male patient with acquired brain damage of the anterior cingulate cortex as a result of an ischemic event in the territory of the left anterior cerebral artery. Cognitive function was assessed using the neuropsychological executive function and frontal lobe test battery (BANFE-2) as well as other neuropsychological tests. The results show a profile of higher mental functions characterized by the presence of dysexecutive syndrome with marked behavioral alteration and diencephalic amnesia. .

关键词： Ischemic Stroke Anterior Cingulate Cortex Neuropsychology Acquired Brain Damage

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Woody plant cell walls:Fundamentals and utilization

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Molecular Plant 2024年第1期17卷 112-140页

作者： Wei Li Ying-Chung jimmy Lin Ying-Lan Chen Chenguang Zhou Shuang Li Nette De Ridder Dyoni M.Oliveira Lanjun Zhange Baocai Zhang Jack P.Wang Changzheng Xu Xiaokang Fu Keming Luo Ai-Min Wu Taku Demura Meng-Zhu Lu Yihua Zhou Laigeng Li Toshiaki Umezawa Wout Boerjan Vincent L.Chiang State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbin 150040China Department of Life Science National Taiwan UniversityTaipeiTaiwanChina Department of Biotechnology and Bioindustry Sciences College of Bioscience and BiotechnologyNational Cheng Kung UniversityTainanTaiwanChina Department of Plant Biotechnology and Bioinformatics Ghent UniversityTechnologiepark 719052 GhentBelgium VIB Center for Plant Systems Biology Technologiepark 719052 GhentBelgium State Key Laboratory of Plant Genomics Insttute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Forest Biotechnology Group Department of Forestry and Environmental ResourcesNorth Carolina State UniversityRaleighNC 27695USA Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation Integrative Science Center of Germplasm CreationSchool of Life SciencesSouthwest UniversityChongqing 400715China Guangdong Key Laboratory for Innovative Developmentand Utilization of Forest Plant Germplasm College of Forestry and Landscape ArchitecturesSouth China Agricultural UniversityGuangzhou510642China Center for Digital Green-innovation Nara Institute of Science and TechnologykomaNara 630-0192Japan State Key Laboratory of Subtropical Siviculture College of Forestry and BiotechnologyZhejang A&F UniversityHangzhou 311300China CAS Center for Excellence in Molecular Plant Sciences Chinese Academy of Sciences300 Fenglin RoadShanghai 200032China Laboratoryof MetabolicScienceofForest Plants and Microorganisms Rsearch Institute for Sustainable HumanosphereKyoto UniversityUjiKyoto 611-0011 Japan

Cell walls in plants,particularly forest trees,are the major carbon sink of the terrestrial *** and biosynthetic features of plant cell walls were revealed early on,focusing mostly on herbaceous model *** developments in genomics,transcriptomics,epigenomics,transgenesis,and associated analytical techniques are enabling novel insights into formation of woody cell ***,we review multilevel regulation of cell wall biosynthesis in forest tree *** highlight current approaches to engineering cell walls as potential feedstock for materials and energy and survey reported field tests of such engineered transgenic *** outline opportunities and challenges in future research to better understand cell type biogenesis for more efficient wood cell wall modification and utilization for biomaterials or for enhanced carbon capture and storage.

关键词： regulation of cell wall formation biosynthesis of cell wall components lignin cellulose hemicellulose cell wall utilization

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Occupational hand injuries:a current review of the prevalence and proposed prevention strategies for physical therapists and similar healthcare professionals

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Journal of Integrative Medicine 2018年第2期16卷 84-89页

作者： Giles Gyer jimmy Michael James Inklebarger The London College of Osteopathic Medicine 8-10 Boston PlaceLondon NWI 6QHUnited Kingdom

Hand injury is the second most common work-related musculoskeletal injury among physical therapists （PTs） and other manual therapy professionals such as osteopaths, physiotherapists, chiropractors, acupuncturists and massage therapists. However, the nature and extent of this problem have not been fully explored yet. Therefore, the objective of this study was to review the existing literature published on the prevalence, risk factors, consequences, and prevention of hand injuries among PTs and similar healthcare professionals. The lifetime prevalence of hand injuries was about 15%-46%, and the annual prevalence was reported as 5%-30%. Thumb injuries were found to be the most prevalent of all injuries, accounting more than 50% of all hand-related problems. The most significant risk factors for job-related hand injuries were performing manual therapy techniques, repetitive workloads, treating many patients per day, continued work while injured or hurt, weakness of the thumb muscles, thumb hypermobility, and instability at the thumb joints. Frs reported modifying treatment technique, taking time off on sick leave, seeking intervention, shifting the specialty area, and decreasing patient contact hours as the major consequences of these injuries. The authors recommend that PTs should develop specific preventive strategies and put more emphasis on the use of aids and equipment to reduce the risk of an unnecessary injury.

关键词： Occupational injuries Public health Physical therapists Occupational therapists Complementary therapies

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Redox flow batteries based on insoluble redox-active materials.A review

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Nano Materials Science 2021年第1期3卷 17-24页

作者： Xiao Wang Jingchao Chai Jianbing“jimmy”Jiang Department of Chemistry University of CincinnatiP.O.Box 210172CincinnatiOH45221-0172United States

The ever-increasing demand for energy has stimulated the development of economical non-fossil *** representative of clean energy,solar and wind have been identified as the most promising energy sources due to their abundance,cost efficiency,and environmental *** intrinsic intermittent of the clean energy leads to the urgent requirements large-scale energy storage *** flow batteries(RFBs)are attractive technology due to their independent control over energy and *** redox-active flow battery is a new type of electrochemical energy storage technology that disperses redox-active particles in the *** with traditional flow batteries,insoluble flow batteries have advantages of large energy density and are very promising in the development of large-scale energy storage *** present,three types of insoluble flow batteries have been explored:slurry-based flow batteries,metal/slurry hybrid,and redox-mediator-assisted flow *** Review summarizes the research progress of insoluble flow batteries,and analyzes the key challenges from the fundamental research and practical application perspectives.

关键词： Membrane Redox flow battery Redox mediator Slurry

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