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新型液晶乳液的开发及多种因素的制造特征研究

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广东化工 2023年第12期50卷 34-40,66页

作者：李恩秀冯家笑金东寅尹钟文李持玟郑弘洙孙钟勋韩佛化妆品(湖州)有限公司浙江湖州313000

本研究利用脂肪酸系列,蔗糖系列,聚甘油酯系列乳化剂和不同极性油脂,对不同浓度参与液晶形成的因素进行了分析。此外,分别配制层状乳化物,通过偏光显微镜观察液晶结构。在3种系列乳化剂中,极性高的油橄榄油,辛酸/癸酸甘油三酯参与了液... 详细信息

本研究利用脂肪酸系列,蔗糖系列,聚甘油酯系列乳化剂和不同极性油脂,对不同浓度参与液晶形成的因素进行了分析。此外,分别配制层状乳化物,通过偏光显微镜观察液晶结构。在3种系列乳化剂中,极性高的油橄榄油,辛酸/癸酸甘油三酯参与了液晶的形成,高级醇(鲸蜡硬脂醇,鲸蜡醇,山嵛醇),应用于3种系列乳化剂,均能确认液晶粒子更清晰,随着高级醇含量的增加,液晶粒子变大。在未形成液晶的蔗糖系列ARLAEL 21211-FL-(MV)乳化剂中,使用高级醇(鲸蜡硬脂醇,鲸蜡醇),结果B-7、B-8、B-9、B-10样品液晶形成均优秀。不使用目前市场上的液晶乳化剂系列,而是使用普通蔗糖系列乳化剂,在乳化体系中采用高级醇(鲸蜡硬脂醇),结果全都形成液晶,证实辛酸/癸酸甘油三酯可以形成更清晰的液晶。

关键词：液晶多层结构表面活性剂高级醇

Intra and extra pelvic multidisciplinary surgical approach of retroperitoneal sarcoma:Case series report

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World Journal of Clinical Cases 2022年第27期10卷 9693-9702页

作者： Heekyoung Song Jung Hwan Ahn Yuyeon Jung Jae Yeon Woo jimin Cha Yang-Guk Chung Keun Ho lee Department of Obstetrics and Gynecology Incheon St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Obstetrics and Gynecology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Orthopaedic Surgery Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Retroperitoneal sarcoma(RPS) is a rare malignancy arising from mesenchymal cells that most commonly presents as an abdominal mass and is associated with poor *** several studies have assessed the survival benefits of wide excision,few have reported detailed methods for achieving wide excision in patients with *** To describe our experience with multidisciplinary surgical resection of RPS using intra-and extra-pelvic *** Multidisciplinary surgery is an anatomical approach that combines intra-and extra-peritoneal access within the same surgery to achieve complete RPS *** retrospective review of the records of patients who underwent multidisciplinary surgery for RPS analyzed surgical and survival *** Eight patients underwent 10 intra-and extra-pelvic surgical resections,and their median mass size was 12.75 cm(range,6-45.5 cm).Using an intrapelvic approach,laparoscopy-assisted surgery was performed in four cases and laparotomy surgery in *** an extrapelvic approach,ilioinguinal and posterior approaches were used in four cases each,and the prone position and midline skin incision were shared in *** patients’ RPS masses were removed completely,and four achieved R0 resection through intra-and extra-pelvic *** median estimated blood loss was 2000 m L(range,300-20000 m L) and the median hospitalization was 12.6 d(range,9-69 d).Reoperation was needed in two patients(one for wound necrosis and the other for bowel perforation and wound necrosis).The median overall survival rate and median progression-free survival were 64.6 and 13.7 mo,*** RPS is therapeutically challenging because of its location and high risk of ***,intra-and extra-pelvic surgical approaches can improve the macroscopic security of the surgical margin.

关键词： Margins of excision Retroperitoneal neoplasms Sarcoma

Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey

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World Journal of Gastroenterology 2009年第1期15卷 86-94页

作者： Ho Gak Kim jimin Han Myung-Hwan Kim Kyu Hyun Cho Im Hee Shin Gwang Ha Kim Jae Seon Kim Jin Bong Kim Tae Nyeun Kim Tae Hyeon Kim Tae Hyo Kim Jae Woo Kim Ji Kon Ryu Young-Soo Moon Jong Ho Moon Sung Jae Park Chan Guk Park Sung-Jo Bang Chang Heon Yang Kyo-Sang Yoo Byung Moo Yoo Kyu Taek lee Dong Ki lee Byung Seok lee Sang Soo lee Seung Ok lee Woo Jin lee Chang Min Cho Young-Eun Joo Gab Jin Cheon Young Woo Choi Jae Bok Chung Yong Bum Yoon Department of Internal Medicine Catholic University of Daegu School of Medicine Daegu 705-718 South Korea Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul 138-736 South Korea Department of Medical Statistics Catholic University of Daegu School of Medicine Daegu 705-718 South Korea Department of Internal Medicine Pusan National University School of Medicine Busan 602-739 South Korea Department of Internal Medicine Korea University College of Medicine Seoul 136-705 South Korea Department of Internal Medicine Hallym University College of Medicine Chuncheon 200-704 South Korea Department of Internal Medicine Yeungnam University College of Medicine Daegu 705-717 South Korea Department of Internal Medicine Wonkwang University College of Medicine Iksan Jeonbuk 570-711 South Korea Department of Internal Medicine Gyeongsang National University School of Medicine Jinju Gyeongnam 660-702 South Korea Department of Internal Medicine Yonsei University Wonju College of Medicine Wonju Gangwon 220-701 South Korea Department of Internal Medicine Seoul National University College of Medicine Seoul 110-799 South Korea Department of Internal Medicine lnje University College of Medicine Seoul 139-713 South Korea Department of Internal Medicine Soonchunhyang University College of Medicine Bucheon Gyunggi 420-767 South Korea Department of Internal Medicine Inje University College of Medicine Busan 614-735 South Korea Department of Internal Medicine Chosun University College of Medicine Gwangju Jeonbuk 501-717 South Korea Department of Internal Medicine Ulsan University Hospital University of Ulsan College of Medicine Ulsan 681-714 South Korea Department of Internal Medicine Dongguk University College of Medicine Gyeongju Gyeongbuk 791-707 South Korea Department of Internal Medicine Hallym University College of Medicine Anyang Gyeonggi 431-070 South Korea Department of Internal Medicine Ajou University School of Medicine Suwon

AIM： To investigate prevalence of C/onorchis sinensis in patients with gastrointestinal symptoms, and the relation of the infection to hepatobiliary diseases in 26 hospitals in Korea. METHODS： Consecutive patients who had been admitted to the Division of Gastroenterology with gastrointestinal symptoms were enrolled from March to April 2005. Of those who had been diagnosed with clonorchiasis, epidemiology and correlation between infection and hepatobiliary diseases were surveyed by questionnaire. RESULTS： Of 3080 patients with gastrointestinal diseases, 396 （12.9%） had clonorchiasis and 1140 patients （37.2%） had a history of eating raw freshwater fish. Of those with a history of raw freshwater fish ingestion, 238 （20.9%） patients had clonorchiasis. Cholangiocarcinoma was more prevalent in C. sinensis-infected patients than nonnfected patients [34/396 （8.6%） vs 145/2684 （5.4%）, P = 0.015]. Cholangiocarcinoma and clonorchiasis showed statistically significant positive cross-relation （P = 0.008）. Choledocholithiasis, cholecystolithiasis, cholangitis, hepatocellular carcinoma, and biliary pancreatitis did not correlate with clonorchiasis. CONCLUSION： Infection rate of clonorchiasis was still high in patients with gastrointestinal diseases in Korea, and has not decreased very much during the last two decades. Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite.

关键词： Clonorchis sinensis Epidemiology Cholangiocarcinoma Korea Multicenter study Clonorchiasis

Wireless,multimodal sensors for continuous measurement of pressure,temperature,and hydration of patients in wheelchair

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npj Flexible Electronics 2023年第1期7卷 479-493页

作者： Seokjoo Cho Hyeonseok Han Hyunwoo Park Sung-Uk lee Jae-Hwan Kim Sung Woo Jeon Mengqiu Wang Raudel Avila Zhaoqian Xi Kabseok Ko Minsu Park Jungyup lee Myungwoo Choi Je-Sang lee Weon Gi Min Byeong-Ju lee Soyeong lee Jungrak Choi jimin Gu Jaeho Park Min Seong Kim Junseong Ahn Osman Gul Chankyu Han Gihun lee Seunghwan Kim Kyuyoung Kim Jeonghyun Kim Chang-Mo Kang Jahyun Koo Sung Soo Kwak Sungbong Kim Dong Yun Choi Seokwoo Jeon Hyung Jin Sung Yong Bae Park Minkyu Je Young Tae Cho Yong Suk Oh Inkyu Park Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Advanced 3D Printing Technology Development Division Korea Atomic Energy Research InstituteDaejeon 34057Republic of Korea Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsDalian University of TechnologyDalian 116023P.R.China Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA DUT-BSU Joint Institute Dalian University of TechnologyDalian 116023China Ningbo Institute of Dalian University of Technology Ningbo 315016China Department of Electronics Engineering Kangwon National UniversityChuncheon 24341Republic of Korea Querrey-Simpson Institute for Bioelectronics Northwestern UniversityEvanstonIL 60208USA Sibel Health Inc NilesIL 60714USA Department of Materials Science and Engineering KAIST Institute for The Nanocentury(KINC)Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Rehabilitation Medicine Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of planning and development Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of rehabilitation medicine Pusan national university hospitalBusan 49241Republic of Korea Department of AI Convergence Network Ajou UniversitySuwon 16499Republic of Korea Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897Republic of Korea Korea Photonics Technology Institute Gwangju 61007Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02841Republic of Korea Interdisciplinary Program in Precision Public Health Korea UniversitySeoul 02841Republic of Korea Center

Individuals who are unable to walk independently spend most of the day in a *** population is at high risk for developing pressure injuries caused by ***,early diagnosis and prevention of these injuries still remain ***,we introduce battery-free,wireless,multimodal sensors and a movable system for continuous measurement of pressure,temperature,and hydration at skin *** device design includes a crack-activated pressure sensor with nanoscale encapsulations for enhanced sensitivity,a temperature sensor for measuring skin temperature,and a galvanic skin response sensor for measuring skin hydration *** movable system enables power harvesting,and data communication to multiple wireless devices mounted at skin-cushion interfaces of wheelchair users over full body *** evaluations and numerical simulations of the devices,together with clinical trials for wheelchair patients,demonstrate the feasibility and stability of the sensor system for preventing pressure injuries caused by sitting.

关键词： injuries modal mounted

Detection of Listeria monocytogenes in Foods and Characterization by PFGE

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Advances in Microbiology 2016年第4期6卷 343-349页

作者： Sanghun Park Hyowon Jung Myungsuk lee Heejin Choi jimin Kim Jihun Jung Sungkyu Park Musang Kim Kyungsik Kim Younghee Oh Aehee Chung Kweon Jung Seoul Metropolitan Government Research Institute of Public Health and Environment Gwacheon-si Korea

The aims of the present study were to investigate the prevalence of Listeria monocytogenes in 1042 foods collected from different market to characterize the isolates by phenotypical and molecular methods. In particular, L. monocytogenes obtained from different types of foods such as RTE (kimbap), fish (smoked salmon and seasoned-dried slice fish) and meat (cut raw beef and pork) from 2009 to 2011, were used. Twelve samples (2.1%) were positive for L. monocytogenes. Detection rate of L. monocytogenes varied significantly by food type and ranged from 1.1% to 5.2%. Meat is the highest prevalence for L. monocytogenes (5.2%) followed by RTE (1.8%) and Fish (1.1%). Twelve isolates were also serotyped by the agglutination method. The most common serotypes detected in the 12 strains tested were 1/4b (75.0%), followed by 1/2a (16.7%), and 1/2b (8.3%). For this study, we used serotyping and detected 6 different virulence-associated genes (inlA, inlB, plcA, plcB, hlyA, and actA) and 16s rRNA using multiplex-PCR. PFGE was performed to determine genetic characterization of L. monocytogenes strains to define the genetic diversity.

关键词： Listeria monocytogenes PFGE RTE

地下水封原油洞库纵向轴线方向选取影响因素浅析

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工程建设 2018年第3期50卷 59-62页

作者：李增涛王敬奎张继民中海油石化工程有限公司土建室山东青岛266101

主洞室开挖纵轴线方向的选取是地下水封原油洞库设计的一个重要环节。其中,两个决定性控制因素是地应力和结构面,两者会直接影响原油洞库开挖的方向。文章结合低地应力区的某大型地下水封原油洞库进行实际案例分析和研究。

关键词：原油洞库纵轴线控制因素

扁桃体鳞癌中HPV感染与EGFR、VEGF表达的相关性研究

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现代肿瘤医学 2015年第4期23卷 461-464页

作者：费继敏 Timothy A Dobbins Deanna Jones C Soon lee Christine Loo Jonathan Clark Barbara Rose 昆明医科大学第三附属医院云南省肿瘤医院头颈外科悉尼大学皇家王子Alfred医院悉尼癌症中心头颈肿瘤研究所云南昆明650018 悉尼UNSW癌症研究中心综合癌症研究部悉尼大学感染性疾病与免疫学系悉尼大学医学院病理教研室悉尼利物浦医院解剖病理科

目的:研究扁桃体鳞癌(squamous cell carcinomas of the tonsil tonsillar,SCCs)中人乳头瘤病毒(human papillomavirus,HPV)感染与血管内皮生长因子(vascular endothelial growth factor,VEGF)和表皮生长因子受体(epidermal growth factor,EGFR)表达的关系,探讨HPV与EGFR和VEGF在扁桃体鳞癌发生中的交互效应。方法:采用多重实时荧光定量聚合酶链反应(multiplex real-time polymerase chain reaction,MT-PCR)检测85例扁桃体鳞癌HPV DNA及型别,通过HPV DNA分析进行HPV感染状况的测定;同时采用半定量免疫组化检测HPV(+)组和HPV(-)组中VEGF、EGFR蛋白表达情况。结果:扁桃体鳞癌中HPV感染率为49.4%(42/85),HPV-16型占所有感染者的比例为90.5%(38/42),明显高于其他型别;HPV(+)组EGFR蛋白表达明显低于HPV(-)组(P值均<0.01);HPV(+)组与HPV(-)组VEGF蛋白表达无明显差异;此外,VEGF表达与EGFR、患者的年龄、性别、TNM分期、组织学分级均无明显相关性。结论:HPV感染与扁桃体鳞癌的发生存在相关性,HPV相关的扁桃体鳞癌中,HPV基因可能通过改变EGFR表达致癌,为HPV致癌机理进一步研究提供一个新的视角,具有重要的理论意义。

关键词：扁桃体癌鳞状细胞癌人乳头瘤病毒血管内皮生长因子表皮生长因子受体