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reuse of port industrial heritage in tourist cities:Shipyards as case studies

Frontiers of Architectural research 2024年第1期13卷 164-183页

作者： María J.Andrade Eduardo jiménez-Morales rachel rodríguez-ramos Pablo Martínez-ramírez Department of Art and Architecture School of ArchitectureMalaga UniversityMalaga 29013Spain

The progressive deindustrialisation of many western cities since the 1980s has led to many industrial zones linked to port activities being abandoned or falling into *** such as Barcelona,Naples,Lisbon,Amsterdam,and Hamburg have port industrial complexes of high tangible and intangible heritage value that could totally or partially disappear,resulting in an irreparable loss of their scientific,architectural,social,technological,and historical *** that in mind,Adaptive reuse(Ar)of the built heritage allows the industrial memory of the ports to be preserved by turning them into new functional centres within the existing urban *** occurs in the context of the contemporary challenges of those cities,such as touristification,the circular economy and climate change,while guaranteeing the life cycle of those *** article analyses two case studies—the Nederlandsche Scheepsbouw Maatschappij(NDSM)and the rotterdamsche Droogdok Maatschappij(rDM)shipyards,both in the Netherlands—in order to contribute to the knowledge of Ar of Port Industrial *** are two examples of good practices in port industrial heritage interventions,where the factors behind their acclaim can be easily highlighted.A multi-scale methodology is therefore used and tailored to the case of port industrial heritage,based on analysing previous studies of the heritage in different spheres and on different scales.A relationship matrix tool is thus *** enables a comparative study to be conducted,using key variables and indicators,and considering qualitative and quantitative *** provides extensive output information for each case study,which is summarised in the most favourable factors for the success of the Ar of this port industrial heritage.

关键词： Industrial heritage Port-city Adaptive reuse Best practices Circular economy HUL Touristification

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An empirical model for high energy density lithium-(ion)batteries with ultra-thick electrodes

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Tungsten 2024年第1期6卷 230-237页

作者： Li-Ming Jin Guang-Guang Xing Nan Qin Yan-Yan Lu Jun-Sheng Zheng Cun-Man Zhang jim P.Zheng School of Automotive Studies and Clean Energy Automotive Engineering Center Tongji UniversityShanghai 201804China Department of Electrical Engineering University at BuffaloThe State University of New YorkBuffaloNY 14260USA

Increasing the electrode thickness is a significant method to decrease the weight and volume ratio of the inactive components for high energy density of the *** this contribution,we extracted a repeating unit in the configurations and establish the empirical energy density model based on some *** this model,the effects of the electrode thickness on the energy density for lithium-ion batteries(LIBs),lithium metal batteries(LMBs),and anode-free lithium batteries(ALBs)are evaluated quantitively with the current parameters of the *** results demonstrate that the structure evolutions from LIBs,LMBs to ALBs with the reduction of the anode weight contribution,the energy density can be well improved *** the increase of the thickness of the electrode provide another route to furthe r enhance the energydensity by decreasing the weight contribution of inactive materials;meanwhile the effects for ALBs are higher than LMBs and LIBs due to the higher weight ratio of inactive *** empirical energy density model is also applied into the practical system and provide intuitional results to guide the battery design for higher energy density.

关键词： Empirical model High energy density Lithium batteries Ultra-thick electrodes

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Emerging concern on air pollution and health:Trade-off between air pollution exposure and physical activity

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Eco-Environment & Health 2024年第2期3卷 202-207页

作者： Pengpeng Wu Qian Guo Yuchen Zhao Mengyao Bian Suzhen Cao Junfeng(jim)Zhang Xiaoli Duan School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China China North Artificial Intelligence&Innovation research Institute Beiing 100072China Collective Intelligence&Collaboration Laboratory Beijing 100072China Nicholas School of the Environment and Global Health Institute Duke UniversityDurhamNC 27708USA Duke Kunshan University Kunshan 215316China

Air pollution is a major contributor to the global disease burden,especially affecting respiratory and cardiovascular ***,physical activity is associated with improved lung function,a slower decline in lung function,and lower *** public is more likely to be exposed to air pollution during outdoor physical ***,studies on how long-term and short-term exposure to air pollution interacts with physical activity yield inconsistent results,and the thresholds for air pollution and physical activity remain ***,more studies are needed to provide sufficient evidence to guide the public to safely engage in outdoor physical activity when exposed to air pollution.

关键词： Air pollution Physical activity Interaction Thresholds Exposure

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A Tutorial on Federated Learning from Theory to Practice:Foundations,Software Frameworks,Exemplary Use Cases,and Selected Trends

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 824-850页

作者： M.Victoria Luzón Nuria rodríguez-Barroso Alberto Argente-Garrido Daniel jiménez-López Jose M.Moyano Javier Del Ser Weiping Ding Francisco Herrera Department of Software Engineering Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain Department of Computer Science and Artificial Intelligence Andalusian Research Institute in Data Science and Computational Intelligence(DaSCI)University of GranadaGranada 18071Spain Department of Communications Engineering University of the Basque Country(UPV/EHU)and also with TECNALIABasque Research&Technology Alliance(BRTA)Spain School of Information Science and Technology Nantong UniversityNantong 226019China

When data privacy is imposed as a necessity,Federated learning(FL)emerges as a relevant artificial intelligence field for developing machine learning(ML)models in a distributed and decentralized *** allows ML models to be trained on local devices without any need for centralized data transfer,thereby reducing both the exposure of sensitive data and the possibility of data interception by malicious third *** paradigm has gained momentum in the last few years,spurred by the plethora of real-world applications that have leveraged its ability to improve the efficiency of distributed learning and to accommodate numerous participants with their data *** virtue of FL,models can be learned from all such distributed data sources while preserving data *** aim of this paper is to provide a practical tutorial on FL,including a short methodology and a systematic analysis of existing software ***,our tutorial provides exemplary cases of study from three complementary perspectives:i)Foundations of FL,describing the main components of FL,from key elements to FL categories;ii)Implementation guidelines and exemplary cases of study,by systematically examining the functionalities provided by existing software frameworks for FL deployment,devising a methodology to design a FL scenario,and providing exemplary cases of study with source code for different ML approaches;and iii)Trends,shortly reviewing a non-exhaustive list of research directions that are under active investigation in the current FL *** ultimate purpose of this work is to establish itself as a referential work for researchers,developers,and data scientists willing to explore the capabilities of FL in practical applications.

关键词： Data privacy distributed machine learning federated learning software frameworks

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Mixed neuroendocrine non-neuroendocrine neoplasms in gastroenteropancreatic tract

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1166-1179页

作者： Sebastián Díaz-López Jerónimo jiménez-Castro Carlos Enrique robles-Barraza Carlos Ayala-de Miguel Manuel Chaves-Conde Medical Oncology Department Hospital Universitario ValmeSeville 41014AndalucíaSpain

Mixed neuroendocrine non-neuroendocrine neoplasms(MiNENs)are a hetero-geneous group of malignant neoplasms that can settle in the gastroenteropan-creatic *** are composed of a neuroendocrine(NE)and a non-NE compo-nent in at least 30%of each *** non-NE component can include different histological combinations of glandular,squamous,mucinous and sarcomatoid phenotypes,and one or both of the components can be low-or high grade *** changes in the nomenclature of these neoplasms might lead to great deal of confusion,and the lack of specific clinical trials is the main reason why their management is *** review aims to clarify the definition of MiNEN and analyze available evidence about their diagnosis and treatment options according to their location and extension through careful analysis of the available *** would be important to reach a general consensus on their diagnosis in order to construct a classification that remains stable over time and facilitates the design of clinical trials that,due to their low incidence,will require long recruitment periods.

关键词： Mixed neuroendocrine non-neuroendocrine neoplasms Mixed adenoneuroendocrine carcinomas Mixed tumours Gastroenteropancreatic Treatment Etiology Diagnosis

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Development of a Lightweight Model for Handwritten Dataset recognition: Bangladeshi City Names in Bangla Script

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Computers, Materials & Continua 2024年第8期80卷 2633-2656页

作者： MdMahbubur rahman Tusher Fahmid Al Farid MdAl-Hasan Abu Saleh Musa Miah Susmita roy rinky Mehedi Hasan jim Sarina Mansor MdAbdur rahim Hezerul Abdul Karim Department of Computer Science and Engineering Bangladesh Army University of Science and Technology(BAUST)Saidpur5310Bangladesh Faculty of Engineering Multimedia UniversityCyberjaya63100Malaysia Pabna University of Science and Technology Pabna6600Bangladesh

The context of recognizing handwritten city names,this research addresses the challenges posed by the manual inscription of Bangladeshi city names in the Bangla *** today’s technology-driven era,where precise tools for reading handwritten text are essential,this study focuses on leveraging deep learning to understand the intricacies of Bangla *** existing dearth of dedicated datasets has impeded the progress of Bangla handwritten city name recognition systems,particularly in critical areas such as postal automation and document ***,no prior research has specifically targeted the unique needs of Bangla handwritten city name *** bridge this gap,the study collects real-world images from diverse sources to construct a comprehensive dataset for Bangla Hand Written City name *** emphasis on practical data for system training enhances *** research further conducts a comparative analysis,pitting state-of-the-art(SOTA)deep learning models,including EfficientNetB0,VGG16,resNet50,DenseNet201,InceptionV3,and Xception,against a custom Convolutional Neural Networks(CNN)model named“Our CNN.”The results showcase the superior performance of“Our CNN,”with a test accuracy of 99.97% and an outstanding F1 score of 99.95%.These metrics underscore its potential for automating city name recognition,particularly in postal *** study concludes by highlighting the significance of meticulous dataset curation and the promising outlook for custom CNN *** encourages future research avenues,including dataset expansion,algorithm refinement,exploration of recurrent neural networks and attention mechanisms,real-world deployment of models,and extension to other regional languages and *** recommendations offer exciting possibilities for advancing the field of handwritten recognition technology and hold practical implications for enhancing global postal services.

关键词： Handwritten recognition Bangladeshi city names Bangla handwritten city name automated postal services

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Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural regeneration research 2025年第4期20卷 1092-1093页

作者： Danko Jeremic Lydia jiménez-Díaz Juan D.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(AD)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in AD,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

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Integrative Analysis of Transcriptome and Phenolic Compounds Profile Provides Insights into the Quality of Soursop (Annona muricata L.) Fruit

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1717-1732页

作者： Yolotzin Apatzingán Palomino-Hermosillo Ángel Elpidio Díaz-Jasso rosendo Balois-Morales Verónica AlhelíOchoa-jiménez Pedro Ulises Bautista-rosales Guillermo Berumen-Varela Unidad de Tecnología de Alimentos-Secretaría de Investigación y Posgrado Universidad Autónoma de Nayarit.Ciudad de la Cultura SNTepic63000NayaritMéxico Programa Académico de Biología Unidad Académica de AgriculturaUniversidad Autónoma de NayaritKm.9.Carretera Tepic-CompostelaXalisco63780NayaritMéxico Estancias Posdoctorales-Consejo Nacional de Humanidades Ciencias y TecnologíasCoordinación de Apoyos a Becarios e InvestigadoresDirección de PosgradoCiudad de México03940México

Soursop(Annona muricata L.)is a tropical fruit highly valued for its uniqueﬂavor,nutritional value,and health-promoting *** ripening process of soursop involves complex changes in gene expression and metabo-lite accumulation,which have been studied using various omics *** analysis has provided insights into the regulation of key genes involved in ripening,while metabolic compound analysis has revealed the presence of numerous bioactive compounds with potential health beneﬁ***,the integration of transcrip-tome and metabolite compound data has not been extensively explored in ***,in this paper,we present a comprehensive analysis of the transcriptome and phenolic compound proﬁles of soursop during *** integration analysis showed that the genes and phenolic compounds were mainly involved in the starch and sucrose metabolism pathways during soursop ***,the phenolic compounds Kaempferol 3-Q-galactoside,Procyanidin C1,Procyanidin trimmer C1,and m-Coumaric,as well as the genes Ubiquitin-like protein 5(UBL5_ArATH),ATP-dependent zinc metalloprotease FTSH8(FTSH8_OrYSJ),Zinc transporter 4(ZIP4_Ar-ATH),Thioredoxin-like 3-1(TrL31_OrYSJ),Mitogen-activated protein kinase YODA(YODA_ArATH),r-man-delonitrile lyase-like(MGL_ArATH),26s protease regulatory subunit 6A homolog(PrS6_SOLLC),Cytochrome P45072A13(C7A13ArATH),Cytochrome P45084A1(C84A1_ArATH)and Homoserine O-trans-acetylase(MET2-OrYSJ)were correlated and differentially accumulated and expressed,*** study provides new insights into the molecular mechanisms underlying soursop ripening and may contribute to the development of strategies for improving the nutritional quality and shelf life of this important fruit.

关键词： Bioinformatics data integration genes metabolites postharvest storage ripening

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Local excision of early rectal cancer: A multi-centre experience of transanal endoscopic microsurgery from the United Kingdom

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World Journal of Gastrointestinal Surgery 2024年第10期16卷 3114-3122页

作者： Ahmed Farid Matthew Tutton Prem Thambi TS Gill jim Khan Department of General Surgery Oncology Center Mansoura UniversityCairo 11432Egypt Department of Colorectal Surgery East Suffolk and North Essex NHS TrustColchester CO11AAEssexUnited Kingdom Department of Colorectal Surgery Portsmouth Hospitals University NHS TrustPortsmouth PO63LYHampshireUnited Kingdom Department of Surgery University Hospital of North TeesStockton on Tees TS18-TS21DarlingtonUnited Kingdom Department of General Surgery Portsmouth Hospitals NHS TrustQueen Alexandra HospitalPortsmouth PO63LYHampshireUnited Kingdom

BACKGrOUND Total mesorectal excision remains the gold standard for the management of rectal cancer however local excision of early rectal cancer is gaining popularity due to lower morbidity and higher acceptance by the elderly and frail *** To investigate the results of local excision of rectal cancer by transanal endoscopic microsurgery(TEMS)approach carried out at three large cancer centers in the United *** TEMS database was retrospectively reviewed to assess demographics,operative findings and post operative clinical and oncological *** is a retro-spective review of the prospective databases,which included all patients operated with TEMS approach,for early rectal cancer(Node-negative T1-T2),selected T3 in unfit/frail *** Two hundred and twenty-two patients underwent TEMS *** included 144 males(64.9%)and 78 females(35.1%),Median age was 71 *** median distance of the tumours from the anal verge 4.5 *** tumour size was 2.6 *** most frequent operative position of the patient was lithotomy(32.3%),Full-thickness rectal wall excision was done in 204 *** operating time was 90 *** blood loss was *** were two 90-day *** excision of the tumour with free microscopic margins by>1mm were accomplished in 171 patients(76.7%).Salvage total mesorectal excision was performed in 42 patients(19.8%).Median disease-free survival was 65 months(range:3-146 months)(82.8%),and median overall survival was 59 months(0-146 months).CONCLUSION TEMS provides a promising option for early rectal cancers(Large adenomas-cT1/cT2N0),and selected therapy-responding ***-thickness complete excision of the tumour is mandatory to avoid jeopardising the oncological outcomes.

关键词： Local excision Transanal endoscopic microsurgery Early rectal cancer rectum preservation rectum saving

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二硫化碳作为谷物熏蒸剂的新观点

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粮油食品科技 2024年第3期32卷 1-15页

作者： jim DESMArCHELIEr Yu XIAO Li GU Yong-lin rEN 李燕羽(译) 默多克大学环境和生命科学学院澳大利亚珀斯WA 6150 国家粮食和物资储备局科学研究院粮食储运研究所

虽然二硫化碳(CS_(2))是一种古老的熏蒸剂,但澳大利亚新数据以及中国和埃及已发表的研究数据使它可被人们重新关注。这些数据包括谷物质量、自然释放和加工食品中的残留,但目前并不广为人知。埃及研究数据显示,即使在400 mg/m^(3)高剂量... 详细信息

虽然二硫化碳(CS_(2))是一种古老的熏蒸剂,但澳大利亚新数据以及中国和埃及已发表的研究数据使它可被人们重新关注。这些数据包括谷物质量、自然释放和加工食品中的残留,但目前并不广为人知。埃及研究数据显示,即使在400 mg/m^(3)高剂量下,二硫化碳对水稻的发芽率和幼芽长度都没有影响。中国研究数据显示,200 mg/m^(3)高剂量对大麦、小麦、玉米、高粱、棉花、胡萝卜等大多数种子发芽率没有影响。本研究中150 mg/L剂量对澳大利亚小麦、大麦以及鹰嘴豆发芽率和幼芽长度的影响数据也证明了这一点。澳大利亚储藏谷物研究实验室(SGrL)的商业规模实验数据表明,二硫化碳在1000~1500 mg·h·L^(-1)的CT值(浓度×时间)范围内可杀死所有受试昆虫,并且对小麦最终产品质量没有影响。二硫化碳在谷物上的吸附力低于甲基溴,且主要是物理吸附。它会在谷物上有残留物,但这些残留物在储存和加工的过程中会被大量降解,而剩余的二硫化二苯醚残留物会在小麦制粉前的清理和润麦过程中减少。在制粉和烘烤的过程中,二硫化碳的残留量会逐渐减少。例如,将含有27 g/m^(3)二硫化碳的小麦在仓内密封放置6 d,然后通风24 h,清理会使制粉前的残留量从6.7 mg/kg降至4.6 mg/kg,润麦会使残留量从4.6 mg/kg降至2.2 mg/kg。在制粉的过程中,残留量会进一步减少,而在面条(甚至在烹饪前)、意大利面以及面包的制作过程中,残留量还会进一步减少。当前检测分析方法无法检测加工产品中的残留量(定量限值<0.005 mg/kg),且其残留水平与同一来源未经二硫化碳熏蒸的小麦制品相同。

关键词：熏蒸剂二硫化碳吸附性发芽率残留

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