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Is iron overload in alcohol-related cirrhosis mediated by hepcidin?

World Journal of Gastroenterology 2009年第46期15卷 5864-5866页

作者： Tariq Iqbal Azzam Diab Douglas G Ward Matthew J Brookes Chris Tselepis jim murray Elwyn Elias Department of Gastroenterology University Hospital BirminghamVincent Drive Depart ment of Cancer Studies University of BirminghamVincent Drive Department of Hematology University Hospital BirminghamVincent Drive

In this case report we describe the relationship between ferritin levels and hepcidin in a patient with alcohol-related spur cell anemia who underwent liver *** demonstrate a reciprocal relation-ship between serum or urinary hepcidin and serum ferritin,which indicates that inadequate hepcidin production by the diseased liver is associated with elevated serum *** ferritin level falls with increasing hepcidin production after *** inflammatory indices(IL6)nor erythropoietin appear to be related to hepcidin expression in this *** suggest that inappropriately low hepcidin production by the cirrhotic liver may contribute substantially to elevated tissue iron stores in cirrhosis and speculate that hepcidin replacement in these patients may be of therapeutic benefi t in the future.

关键词： Alcohol Iron Anaemia Hepcidin Cirrhosis

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21世纪人们吃什么?

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英语学习 2001年第5期 33-33页

作者： jim murray 国华彭宇

21世纪人们吃什么?科学家说:GM food(转基因食品)。关于转基因食品,近几年西方国家,特别是西欧国家,报纸上、电视上议论纷纷,反对的声音似乎淹没了赞同的声音,有些反对派甚至付诸于行动,捣毁试验田。让我们听一听专家莫端的看法。

关键词：转基因食品滴滴涕

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Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma:Results from the FINBAR study

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World Journal of Gastroenterology 2007年第10期13卷 1585-1594页

作者： Lesley A Anderson RG Peter Watson Seamus J Murphy Brian T Johnston Harry Comber jim Mc Guigan John V Reynolds Liam J murray Centre for Clinical and Population Sciences Queen's UniversityBelfastNorthern Ireland Royal Group of Hospitals BelfastNorthern Ireland National Cancer Registry CorkIreland St.James's Hospital DublinIreland

AIM:To investigate risk factors associated with Barrett's oesophagus and oesophageal ***:This all-Ireland population-based case-control study recruited 224 Barrett's oesophagus patients,227 oesophageal adenocarcinoma patients and 260 *** participants underwent a structured interview with information obtained about potential lifestyle and environmental risk ***:Gastro-oesophageal reflux was associated with Barrett's [OR 12.0(95% CI 7.64-18.7)] and oesophageal adenocarcinoma [OR 3.48(95% CI 2.25-5.41)].Oesophageal adenocarcinoma patients were more likely than controls to be ex-or current smokers [OR 1.72(95% CI 1.06-2.81)and OR 4.84(95% CI 2.72-8.61)respectively] and to have a high body mass index [OR 2.69(95% CI 1.62-4.46)].No significant associations were observed between these risk factors and Barrett's *** but not vegetables were negatively associated with oesophageal adenocarcinoma [OR 0.50(95% CI 0.30-0.86)].CONCLUSION:A high body mass index,a diet low in fruit and cigarette smoking may be involved in the progression from Barrett's oesophagus to oesophageal adenocarcinoma.

关键词： Barrett's oesophagus Oesophagealadenocarcinoma Smoking Gastro-oesophageal reflux Body mass index Diet Case-control

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The 3rd Global Summit of Research Institutes for Disaster Risk Reduction:Expanding the Platform for Bridging Science and Policy Making

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International Journal of Disaster Risk Science 2017年第2期8卷 224-230页

作者： Andrew Collins Hirokazu Tatano Wilma James Chadia Wannous Kaoru Takara Virginia murray Charles Scawthorn jim Mori Sarah Aziz Khalid M.Mosalam Stefan Hochrainer-Stigler Irasema Alcántara-Ayala Elisabeth Krausmann Wei-Sen Li Ana Maria Cruz Subhajyoti Samaddar Tom De Groeve Yuichi Ono Kelvin Berryman Koji Suzuki Mark Ashley Parry Peter McGowran John G.Rees Department of Geography/Disaster and Development Network (DDN) Northumbria University Disaster Prevention Research Institute (DPRI) Kyoto University United Nations Office for Disaster Risk Reduction (UNISDR) Public Health England United Nations Office for Disaster Reduction (UNISDR) Scientific and Technical Advisory Group and Integrated Research on Disaster Risk (IRDR) Scientific Committee Pacific Earthquake Engineering Research Center (PEER) University of CaliforniaBerkeley Centre for Southeast Asia Disaster Prevention Research Initiative (SEADPRI) Universiti Kebangsaan Malaysia Department of Civil and Environmental Engineering Pacific Earthquake Engineering CenterUniversity of CaliforniaBerkeley International Institute for Applied Systems Analysis (IIASA) Institute of Geography National Autonomous University of Mexico (UNAM) European Commission Joint Research Centre (JRC) APEC Emergency Preparedness Capacity Building Center (EPCC) International Research Institute of Disaster Science Tohoku University Natural Hazards Division GNS Science National Research Institute for Earth Science and Disaster Resilience (NIED) British Geological Survey and Research Councils UK

The Global Alliance of Disaster Research Institutes held its 3rd Global Summit of Research Institutes for Disaster Risk Reduction at the Disaster Prevention Research Institute,Kyoto University,Japan,19–21 March,*** Global Alliance seeks to contribute to enhancing disaster risk reduction(DRR) and disaster resilience through the collaboration of research organizations around the *** summit aim was to expand the platform for bridging science and policy making by evaluating the evidence base needed to meet the expected outcomes and actions of the Sendai Framework for Disaster RiskReduction 2015–2030 and its Science and Technology *** summit reflected the international nature of collaborative research and action.A pre-conference questionnaire filled out by Global Alliance members identified323 research projects that are indicative of current *** were categorized to support seven parallel discussion sessions related to the Sendai Framework priorities for *** discussion sessions focused on research that aims to deepen the understanding of disaster *** cross-cutting sessions focused on research that is aimed at the priorities for action on governance,resilience,and *** summaries were presentedin plenary sessions in support of outcomes for widely enhancing the science and policy of DRR.

关键词： Disaster risk reduction research GADRI global summit Policy Science

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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

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