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篇章、语篇、信息

Association between serum malondialdehyde levels and mortality in patients with severe brain trauma injury

语言文字学 2011年第5期 137-146页

作者： m.A.K.韩礼德

“篇章”和“语篇”指的是同一种事物，只是看问题的角度不同。语篇分析就是把篇章跟语言的系统联系起来。作者认为，语篇有各种变体，语码变体跟语域、语类无关。文学语言的特殊性源于语法隐喻。从事语篇分析的学者都是从自己特定的角... 详细信息

“篇章”和“语篇”指的是同一种事物，只是看问题的角度不同。语篇分析就是把篇章跟语言的系统联系起来。作者认为，语篇有各种变体，语码变体跟语域、语类无关。文学语言的特殊性源于语法隐喻。从事语篇分析的学者都是从自己特定的角度出发的，如，批评话语分析、积极话语分析。很多意义是不能量化的，我们不仅要重视概念意义，也要重视人际意义。作者还论证了计算机对语篇分析、机器翻译的作用。

关键词：语篇分析系统功能语言学信息技术 discourse analysis systemic-functional linguistics information technology

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中华神经外科疾病研究杂志 2014年第4期13卷 372-372页

作者： Lorente L martín mm Abreu-González P Ramos L Argueso m Cáceres JJ Solé-Violán J Lorenzo Jm molina I jiménez A. Hospital Universitario de Canarias Intensive Care

There is a hyperoxidative state in patients with trauma brain injury( TBI). malondialdehyde( mDA) is an end-product formed during oxidative stress,concretely lipid peroxidation. In small studies( highest sample size 50 patients),higher levels of mDA have been found in non-surviving than surviving TBI patients. However,an association between serum mDA levels and mortality in patients with TBI has not been reported. Thus,the objective of this prospective,observational,multicenter study,carried out in six Spanish Intensive Care Units,was to determine whether mDA serum levels are associated with early mortality in a large series of patients with severe TBI. Serum mDA levels were measured in 100 patients with severe TBI on day 1 and in 75 healthy controls. The end-point of the study was 30-day *** found higher serum mDA levels in patients with severe TBI than in healthy controls( P m mDA levels( P m mDA levels were associated with 30-day mortality( OR = 4. 662; 95% CI = 1. 466- 14. 824; P = 0. 01),controlling for Glasgow coma score,age and computed tomography findings. Survival analysis showed that patients with serum mDA levels higher than 1. 96 nmol /mL presented increased 30-day mortality than patients with lower levels( Hazard ratio =3. 5; 95% CI =1. 43-8. 47; P most relevant new finding of our study,the largest to date on serum mDA levels in patients with severe TBI,was an association between serum mDA levels and early mortality.

关键词：摘要编辑部编辑工作作者读者

烟草轻简高效栽培技术研究——Ⅲ.m型宽垄双行种植模式对烟草生长及产质量的影响

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中国烟草科学 2011年第5期32卷 29-33页

作者：王树林史万华刘好宝宋俊邢小军王勇焦蓉王全贞侯娜白岩靳义荣张琼芬农业部烟草类作物质量控制重点开放试验室中国农业科学院烟草研究所青岛266101 中国农业科学院研究生院北京100081 四川省烟草公司凉山州公司四川西昌615000

为降低劳动强度,提高种烟的经济效益,采用田间小区试验的方法,研究了m型宽垄双行种植模式的应用效果。结果表明,与单垄单行种植模式相比,打顶期m型宽垄双行种植模式中部叶面积增大4.9%,上部叶面积增大26.19%,通过地膜半幅覆盖提高人工... 详细信息

为降低劳动强度,提高种烟的经济效益,采用田间小区试验的方法,研究了m型宽垄双行种植模式的应用效果。结果表明,与单垄单行种植模式相比,打顶期m型宽垄双行种植模式中部叶面积增大4.9%,上部叶面积增大26.19%,通过地膜半幅覆盖提高人工覆膜效率,可节省地膜22.2%,而且便于机械化操作,有利于实现农机与农艺的有机结合;该种植模式平均增产149.5 kg/hm2,节本增效5 426.57元/hm2,而且能提高烤后烟叶的还原糖、总糖、钾含量,使烟叶化学成分更加协调,是一种新的种植模式,推广应用前景广阔。

关键词：烟草轻简栽培区域轮作宽垄双行节本增效

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IEEE主席声明

科技纵览 2018年第11期 9-9页

作者：吉姆·杰弗里何塞·m.F.莫拉凯伦·巴特利森 IEEE

今年早些时候,美国国家科学院、工程院和医学院发布了一项重要的共识研究报告,标题为《针对女性的性骚扰:风气、文化以及对学术科学、工程和医学的影响》。本期“本刊视线”文章由美国国家工程学院院长和该报告的其中两名作者进行编写,... 详细信息

今年早些时候,美国国家科学院、工程院和医学院发布了一项重要的共识研究报告,标题为《针对女性的性骚扰:风气、文化以及对学术科学、工程和医学的影响》。本期“本刊视线”文章由美国国家工程学院院长和该报告的其中两名作者进行编写,进一步阐述了他们的调查结果。

关键词： IEEE 工程学院调查结果科学院医学院工程院美国

Dielectric relaxation studies of binary mixture of β-picoline and methanol using time domain reflectometry at different temperatures

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Journal of Advanced Dielectrics 2016年第3期6卷 56-63页

作者： C.m.Trivedi V.A.Rana P.G.Hudge A.C.Kumbharkhane Department of Physics Gujarat University Ahmedabad-380009GujaratIndia Allied Sciences Department MKSSS's Cummins College of Engineering PuneMaharashtraIndia School of Physical Sciences Swami Ramanand Teerth Marathawada UniversityNandedMaharashtraIndia

Complex permittivity spectra of binary mixtures of varying concentrations of β-picoline and methanol(meOH)have been obtained using time domain reflectometry(TDR)technique over frequency range 10 mHz to 25 GHz at 283.15,288.15,293.15 and 298.15K *** dielectric relaxation parameters namely static permittivity(ε),high frequency limit permittivity(ε∞1)and the relaxation time(τ)were determined by fiting complex permittivity data to the single Debye/Cole-Davidson *** nonlinear least square(CNLS)fiting procedure was carried out using LEVmW *** excess permittivity(ε_(0)^(E))and the excess inverse relaxation time(1/τ)^(E) which contain information regarding molecular structure and interaction between polar-polar liqids were also *** the experimental data,parameters such as effective Kirkwood correlation factor(geff),Bruggeman factor(fB)and some thermo dynamical parameters have been *** parameters were fitted to the Redlich-Kister polynomial *** values of static permittivity and relaxation time increase nonlinearly with increase in the mol-fraction of meOH at all *** values of excess static permittivity(ε_(0)^(E))and the excess inverse relaxation time(1/τ)^(E) are negative for the studied β-picoline meOH system at all temperatures.

关键词： Complex permittivity relaxation time time domain reflectometry CNLS fitting Redlich-Kister equation β-picoline

国际卒中遗传学联盟的推荐意见（第1部分）：标准化表型数据收集

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国际脑血管病杂志 2015年第9期23卷 645-650页

作者： Jennifer J. majersik John W.Cole Jonathan Golledge Natalia S. Rost Yu-Feng Yvonne Chan m. Edip Gurol Ame G. Lindgren Daniel Woo Israel Fernandez-Cadenas Donna T. Chen Vincent Thijs Bradford B. Worrall Ayeesha Kamal Paul Bentley Joanna m. Wardlaw Ynte m. Ruigrok Thomas W.K Battey Reinhold Schmidt Joan montaner Anne-Katrin Giese Jaume Roquer Jordi jimenez-Conde Chaeyoung Lee Hakan Ay Juan Jose martin 李海峰岳耀先徐军不详山东大学齐鲁医院神经内科济南250012

与几乎所有复杂疾病一样,卒中的患病风险和临床转归也是多基因作用的[1]。探索相关基因突变有望为新型个体化治疗方法奠定基础,从而显著减少卒中对全球健康造成的毁灭性影响。为了达到足够的统计学效能以确认多个风险性等位基因,需要很... 详细信息

与几乎所有复杂疾病一样,卒中的患病风险和临床转归也是多基因作用的[1]。探索相关基因突变有望为新型个体化治疗方法奠定基础,从而显著减少卒中对全球健康造成的毁灭性影响。为了达到足够的统计学效能以确认多个风险性等位基因,需要很大的样本量。尽管卒中是全世界范围内第二大致死病因和成年人致残的主要原因[2],但没有任何一家研究机构能独立收集到足够的样本。在认识到这一挑战之后,来自世界各地的卒中研究者们于2007年成立了国际卒中遗传学联盟（ International Stroke Genetics Consortium, ISGC； http：//www. ***）,其使命是通过研究在全球多个研究机构入组的患者来识别影响卒中患病风险、临床预后和治疗效果的遗传学因素。尽管先前已取得了一些成功[3-5],仍有大量工作有待进行,这不仅是为了发现风险性等位基因从而达到卒中个体化医疗的最终目标,更是为了开发综合性卒中风险评估手段以及得到足以改变临床实践的结果[6]。根据糖尿病和冠状动脉疾病等其他复杂疾病的研究进展,为了识别与卒中相关的所有基因突变,需要100000～200000个样本。为了达到这个样本量,需要进行更为广泛的协作。

关键词：遗传学因素数据收集卒中国际标准化个体化医疗表型冠状动脉疾病

用于绝热发动机部件的部份稳定氧化锆陶瓷(PSZ)

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柴油机 1984年第9期 25-28页

作者： m.E.Woods Isao Qda 朱国朝陈家骅日本NGK绝热材料公司美国cummins柴油机公司

部份稳定氧化锆(PSZ)是一种隔热陶瓷,具有高强度,高热膨胀及耐磨损等特性。低的热传导性达到了隔热要求,高的强度提高了可靠性,高的热膨性为陶瓷发动机部件提供了一种简单的连接方法。活塞、缸套和缸盖已用部份稳定氧化锆隔热,并在一台... 详细信息

部份稳定氧化锆(PSZ)是一种隔热陶瓷,具有高强度,高热膨胀及耐磨损等特性。低的热传导性达到了隔热要求,高的强度提高了可靠性,高的热膨性为陶瓷发动机部件提供了一种简单的连接方法。活塞、缸套和缸盖已用部份稳定氧化锆隔热,并在一台绝热柴油机上进行了试验。

关键词： PSZ 绝热发动机缸盖缸套陶瓷发动机氧化错发动机部件零部件热膨胀性单晶相立方晶

International guideline on natural orifice specimen extraction surgery(NOSES)for colorectal cancer(2023 version)

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Holistic Integrative Oncology 2023年第1期2卷 93-100页

作者： Zheng Liu Xu Guan mingguang Zhang Xiyue Hu ming Yang Junge Bai Jun Li Shaojun Yu Kefeng Ding Qingsi He Liang Kang Dan ma Chuangang Fu Junhong Hu Ye Wei Donghui Sun Gang Yu Songbing He Changyou Wang Yanwei Gao Guiyu Wang Hongliang Yao Jian Peng Yangchun Zheng Bo Jiang Taiyuan Li Zhiguo Xiong Xuejun Sun Zhenning Wang William meng William Tzu-Liang Chen ming-Yin Shen John H.marks Charles A.Ternent Darcy DShaw jim SKhan Petr Tsarkov Inna Tulina Sergey Efetov Joaquim manuel da Costa Pereira Fernanda Nogueira Ricardo Escalante Joel Leroy Avanish Saklani Audrius Dulskas Cuneyt Kayaalp Atsushi Nishimura Kay Uehara Woo-Yong Lee Sang-Hoo Kim Suk-Hwan Lee Xishan Wang Committee of Colorectal Cancer Society Chinese Anti-Cancer Association International NOSES Alliance Department of Colorectal Surgery National Cancer CenterNational Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100021China Department of Colorectal Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of General Surgery Shandong University Qilu HospitalJinanShandongChina Department of Colorectal Surgery The Sixth Affiliated HospitalSun Yat-Sen UniversityGuangzhouChina Department of General Surgery Xinqiao HospitalThird Military Medical UniversityChongqingChina Department of Gastrointestinal Surgery Shanghai East HospitalTongji University School of MedicineShanghaiChina Department of Anorectal Surgery First Affiliated HospitalZhengzhou UniversityZhengzhouHenanChina Department of General Surgery Zhongshan HospitalFudan UniversityShanghaiChina Department of Gastric and Colorectal Surgery Jilin University First HospitalChangchunChina Department of General Surgery Qilu Hospital(Qingdao)Cheeloo College of MedicineShandong UniversityJinanChina Department of General Surgery the First Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina Affiliated Hospital of North China University of Science and Technology TangshanHebeiChina Inner mongolia Autonomous Region People’s Hospital HuhhotInner Mongolia Autonomous RegionChina Department of Colorectal Cancer Surgery the Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangChina Department of General Surgery The Second Xiangya HospitalCentral South UniversityChangshaHunanChina Department of General Surgery Xiangya HospitalCentral South UniversityChangshaChina Department of Gastrointestinal Surgery Sichuan Cancer HospitalChengduChina Department of Colorectal and Anal Surgery Shanxi Cancer HospitalTaiyuanShanxiChina Department of General Surgery The First Affiliated Hospital of Nanchang UniversityNanchangChina Department of Gastrointestinal Surgery Hubei Provincial Cancer Hosp

Purpose In recent years,natural orifice specimen extraction surgery(NOSES)has gained widespread attention as an alternative *** the safety and feasibility of NOSES have been well documented,many questions remain open for *** aim of this guideline is to provide more evidence for the promotion of *** This guideline has been prepared by the CACA Committee of Colorectal Cancer Society and the International NOSES Alliance,based on the latest *** The guideline on NOSES for colorectal cancer include the definition,classification,technology requirement,indications,technical difficulties and clinical *** The guideline provides a full introduction of the theoretical and technical aspects of NOSES for colorectal cancer which will beneficial to development of NOSES.

关键词： Colorectal cancer Guideline Treatment Surgery Holistic integrative medicine Natural orifice specimen extraction surgery

IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

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International Journal of Oral Science 2020年第1期12卷 31-39页

作者： Angustias Page Ana Bravo Cristian Suarez-Cabrera Raquel Sanchez-Baltasar marta Oteo miguel Angel morcillo mLlanos Casanova Jose CSegovia manuel Navarro Angel Ramirez molecular Oncology Unit.Centro de Investigaciones Energéticas Medioambientales y Tecnológicas(CIEMAT)MadridSpain Instituto de Investigación 12 de Octubre i+12 MadridSpain Centro de Investigación Biomédica en Red de Cáncer(CIBERONC) MadridSpain Department of Anatomy Animal Production and Veterinary Clinical SciencesLaboratory of Pathology Phenotyping of Genetically Engineered MiceFaculty of Veterinary MedicineUniversity of Santiago de CompostelaLugoSpain Biomedical Applications and Pharmacokinetics Unit Centro de Investigaciones EnergéticasMedioambientales y Tecnológicas(CIEMAT)MadridSpain Hematopoietic Innovative Therapies Division.Centro de Investigaciones Energéticas Medioambientales y Tecnológicas(CIEMAT).Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)MadridSpain Unidad mixta de Terapias Avanzadas Fundación Instituto de Investigaciones Sanitarias Fundación Jiménez DíazMadridSpain

Odontogenic tumours are a heterogeneous group of lesions that develop in the oral cavity region and are characterized by the formation of tumoural structures that differentiate as teeth. Due to the diversity of their histopathological characteristics and clinical behaviour, the classification of these tumours is still under debate. Alterations in morphogenesis pathways such as the Hedgehog,mAPK and WNT/β-catenin pathways are implicated in the formation of odontogenic lesions, but the molecular bases of many of these lesions are still unknown. In this study, we used genetically modified mice to study the role of IKKβ(a fundamental regulator of NF-κB activity and many other proteins) in oral epithelial cells and odontogenic tissues. Transgenic mice overexpressing IKKβ in oral epithelial cells show a significant increase in immune cells in both the oral epithelia and oral submucosa. They also show changes in the expression of several proteins and mi RNAs that are important for cancer development. Interestingly, we found that overactivity of IKKβ in oral epithelia and odontogenic tissues, in conjunction with the loss of tumour suppressor proteins(p53, or p16 and p19), leads to the appearance of odontogenic tumours that can be classified as ameloblastic odontomas, sometimes accompanied by foci of secondary ameloblastic carcinomas. These tumours show NF-κB activation and increased β-catenin *** findings may help to elucidate the molecular determinants of odontogenic tumourigenesis and the role of IKKβ in the homoeostasis and tumoural transformation of oral and odontogenic epithelia.

关键词： IKKβ tumour suppressor