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The physical and physiological effects of vacuum massage on the different skin layers: a current status of the literature

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Burns & Trauma 2016年第3期4卷 180-191页

作者： Peter Moortgat Mieke Anthonissen jill meirte Ulrike Van Daele Koen Maertens OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 18B-2170 AntwerpBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 18B-2170 AntwerpBelgium Department of Rehabilitation Sciences KU LeuvenTervuursevest 101box 15003001 HeverleeBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 18B-2170 AntwerpBelgium Department of Rehabilitation Sciences and Physiotherapy University of AntwerpUniversiteitsplein 12610 AntwerpBelgium Department of Rehabilitation Sciences and Physiotherapy University of AntwerpUniversiteitsplein 12610 AntwerpBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 18B-2170 AntwerpBelgium Department of Clinical and Lifespan Psychology Vrije Universiteit BrusselPleinlaan 21050 BrusselsBelgium

Vacuum massage is a non-invasive mechanical massage technique performed with a mechanical device that lifts the skin by means of suction,creates a skin fold and mobilises that skin *** the late 1970s,this therapy was introduced to treat traumatic or burn *** vacuum massage was invented to treat burns and scars,one can find very little literature on the effects of this ***,the aim of this review is to present an overview of the available literature on the physical and physiological effects of vacuum massage on epidermal and dermal skin structures in order to find the underlying working mechanisms that could benefit the healing of burns and *** discussion contains translational analysis of the results and provides recommendations for future research on the *** extended search for publications was performed using PubMed,Web of Science and Google *** authors independently identified and checked each study against the inclusion *** articles were included in the qualitative *** two most reported physical effects of vacuum massage were improvement of the tissue hardness and the elasticity of the *** physical effects,a variety of physiological effects are reported in literature,for example,an increased number of fibroblasts and collagen fibres accompanied by an alteration of fibroblast phenotype and collagen *** information was found on the decrease of pain and itch due to vacuum *** vacuum massage initially had been developed for the treatment of burn scars,this literature review found little evidence for the efficacy of this *** in duration,amplitude or frequency of the treatment have a substantial influence on collagen restructuring and reorientation,thus implying possible beneficial influences on the healing potential by mechanotransduction *** massage may release the mechanical tension associated with scar retraction and thus in

关键词： Vacuum massage Endermology Vacuotherapy Depressomassage Scars Hypertrophic Physical Physiological Intervention

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Status of adult inpatient burn rehabilitation in Europe: are we neglecting metabolic outcomes?

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Burns & Trauma 2021年第1期9卷 613-628页

作者： David R.Schieffelers Eric van Breda Nick Gebruers jill meirte Ulrike Van Daele Multidisciplinary Metabolic Research Unit(M2RUN) MOVANT Research GroupDepartment of Rehabilitation Sciences and PhysiotherapyFaculty of Medicine and Health SciencesUniversity of AntwerpUniversiteitsplein 12610WilrijkAntwerpBelgium Multidisciplinary Edema Clinic Antwerp University HospitalWilrijkstraat 102650EdegemAntwerpBelgium OSCARE Organisation for burnsscar after-care and researchVan Roiestraat 182170 MerksemAntwerpBelgium

Background:Hypermetabolism,muscle wasting and insulin resistance are challenging yet important rehabilitation targets in the management of *** the absence of concrete practice guidelines,however,it remains unclear how these metabolic targets are currently *** study aimed to describe the current practice of inpatient rehabilitation across ***:An electronic survey was distributed by the European Burn Association to burn centres throughout Europe,comprising generic and profession-specific questions directed at therapists,medical doctors and *** concerned exercise prescription,metabolic management and treatment priorities,motivation and knowledge of burn-induced metabolic *** ratios were computed to analyse associations between data derived from the responses of treatment priorities and knowledge of burn-induced metabolic ***:Fifty-nine clinicians with 12.3±9 years of professional experience in burns,representing 18 out of 91 burn centres(response rate,19.8%)across eight European countries *** and aerobic exercises were only provided by 42%and 38%of therapists to intubated patients,87%and 65%once out-of-bed mobility was possible and 97%and 83%once patients were able to leave their hospital room,*** assessment of resting energy expenditure by indirect calorimetry,muscle wasting and insulin resistance was carried out by only 40.7%,15.3%and 7.4%respondents,respectively,with large variability in employed frequency and *** all clinicians changed their care in cases of hypermetabolism(59.3%),muscle wasting(70.4%)or insulin resistance(44.4%),and large variations in management strategies were *** interdisciplinary variation was present in treatment goal importance ratings,motivation and knowledge of burn-induced metabolic *** prevention of metabolic sequelae was regarded as the least important treatment goal,while the restoration of functional status

关键词： Burn care Burn rehabilitation Exercise Early mobilization Hypermetabolism Adults

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Short-term effects of vacuum massage on epidermal and dermal thickness and density in burn scars: an experimental study

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Burns & Trauma 2016年第3期4卷 216-224页

作者： jill meirte Peter Moortgat Mieke Anthonissen Koen Maertens Cynthia Lafaire Lieve De Cuyper Guy Hubens Ulrike Van Daele OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 182170 AntwerpBelgium Rehabilitation Sciences and Physiotherapy University of AntwerpUniversiteitsplein 12610 AntwerpBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 182170 AntwerpBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 182170 AntwerpBelgium KU Leuven Faculty of Kinesiology and Rehabilitation SciencesLeuvenBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 182170 AntwerpBelgium Department of Clinical and Lifespan Psychology Vrije Universiteit BrusselBrusselsBelgium OSCARE Organisation for BurnsScar After-care and ResearchVan Roiestraat 182170 AntwerpBelgium ZNA Stuivenberg Burn CenterAntwerpBelgium Department of Antwerp Surgical Training Anatomy and Research Centre University of AntwerpAntwerpBelgium Rehabilitation Sciences and Physiotherapy University of AntwerpUniversiteitsplein 12610 AntwerpBelgium

Background:Vacuum massage is a non-invasive mechanical massage technique invented to treat burns and *** date,no effects of vacuum massage on thickness and density of human scar tissue have been *** process in which external stimuli are converted into biochemical responses in the cell is known as *** the skin endothelial cells,fibroblasts and myofibroblasts embedded in the extracellular matrix(ECM)sense mechanical stimuli(created by vacuum massage)and may promote intracellular processes leading to matrix *** mechanotransduction could be a plausible working mechanism for vacuum massage as an anti-scarring therapy,this study aims to investigate the short-term effects of vacuum massage on thickness and density of epidermis and dermis in burn scars in order to find proof of ECM ***:A one group experimental study was *** with burn scars on upper extremities,lower extremities,and trunk were recruited for participation in this *** DUB?cutis 22 MHz ultrasound scanner was used to assess thickness and density of the epidermal and dermal skin *** baseline measurements,vacuum massage was performed according to a pre-defined *** were carried out at 5 min,30 min,1 h,and 2 h ***:Thirteen scar sites from 9 different patients were *** 8 out of the 13 scar sites,a disruption of the epidermis was noticed after the vacuum *** minutes after the intervention,epidermal density decreased statistically significantly(p=.022)and dermal thickness increased(p=.018).Both changes lasted for more than 1 h,but after 2 h,the changes were no longer statistically *** density decreased significantly(p=.048)immediately after the intervention,and this decrease was still present after 2 h(p=.011).Conclusions:Preliminary results show that the disruption of the epidermis may indicate that vacuum massage could be able to actually breach the s

关键词： Burn Scars Vacuum massage Dermal thickness Dermal density

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Perturbation Theory for Solutions to Second Order Elliptic Operators with Complex Coefficients and the L^p Dirichlet Problem

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Acta Mathematica Sinica,English Series 2019年第6期35卷 749-770页

作者： Martin DINDO? jill PIPHER School of Mathematics The University of Edinburgh and Maxwell Institute of Mathematical Sciences Department of Mathematics Brown University

We establish a Dahlberg-type perturbation theorem for second order divergence form elliptic operators with complex coefficients. In our previous paper, we showed the following result: If L_0 = div A^0(x)? + B^0(x) · ? is a p-elliptic operator satisfying the assumptions of Theorem 1.1 then the LpDirichlet problem for the operator L_0 is solvable in the upper half-space Rn+. In this paper we prove that the Lpsolvability is stable under small perturbations of L_0. That is if L_1 is another divergence form elliptic operator with complex coefficients and the coefficients of the operators L_0 and L_1 are sufficiently close in the sense of Carleson measures, then the LpDirichlet problem for the operator L_1 is solvable for the same value of p. As a corollary we obtain a new result on Lpsolvability of the Dirichlet problem for operators of the form L = div A(x)? + B(x) · ? where the matrix A satisfies weaker Carleson condition(expressed in term of oscillation of coefficients). In particular the coefficients of A need no longer be differentiable and instead satisfy a Carleson condition that controls the oscillation of the matrix A over Whitney boxes. This result in the real case has been established by Dindoˇs,Petermichl and Pipher.

关键词： Complex coefficients elliptic PDEs perturbation theory boundary value problems

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Gairvof-function mutant p53:history and speculation

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Journal of Molecular Cell Biology 2019年第7期11卷 605-609页

作者： jill Bargonetti Carol Prives Department of Biological Sciences Hunter College and The Graduate Center City University of New YorkNew YorkNY 10021USA Department of Biological Sciences Columbia UniversityNew YorkNY 10027USA

Arnold Levine and the history of p53 The history of the p53 tumor suppressor (and of the p53 field of research) is quite *** discovered in the late 1970s as a protein associated with the SV40 large tumor antigen (and also as a protein that was found in some nonvirally transformed cells),p53 was commonly viewed as a facilitator of oncogenic cell transformation (for an excellent review of the early history of p53 see Levine and Oren,2009).It took nearly 10 years for the cancer research field to realize that wild-type p53 is a tumor suppressor protein.

关键词： Levine suppressor protein

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Frame loss error concealment for SVC

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第5期7卷 677-683页

作者： PANDIT Purvin BOYCE jill THOMSON Corporate Research Princeton NJ 08540 USA

Scalable video coding (SVC), as the Scalable Extension of H.264/AVC, is an ongoing international video coding standard designed for network adaptive or device adaptive applications and also offers high coding efficiency. However, packet losses often occur over unreliable networks even for base layer of SVC and have severe impact on the playback quality of compressed video. Until now, no literature has discussed error concealment support for standard SVC bit-stream. In this paper, we provide robust and effective error concealment techniques for SVC with spatial scalability. Experimental results showed that the proposed methods provide substantial improvement, both subjectively and objectively, without a significant complexity overhead.

关键词： Adaptive systems Coding errors Computer networks Image compression Robustness (control systems) Standards

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gFACs:Gene Filtering,Analysis,and Conversion to Unify Genome Annotations Across Alignment and Gene Prediction Frameworks

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Genomics, Proteomics & Bioinformatics 2019年第3期17卷 305-310页

作者： Madison Caballero jill Wegrzyn Department of Ecology and Evolutionary Biology University of Connecticut

Published genomes frequently contain erroneous gene models that represent issues associated with identification of open reading frames,start sites,splice sites,and related structural *** source of these inconsistencies is often traced back to integration across text file formats designed to describe long read alignments and predicted gene *** addition,the majority of gene prediction frameworks do not provide robust downstream filtering to remove problematic gene annotations,nor do they represent these annotations in a format consistent with current file *** frameworks also lack consideration for functional attributes,such as the presence or absence of protein domains that can be used for gene model *** provide oversight to the increasing number of published genome annotations,we present a software package,the Gene Filtering,Analysis,and Conversion(gFACs),to filter,analyze,and convert predicted gene models and *** software operates across a wide range of alignment,analysis,and gene prediction files with a flexible framework for defining gene models with reliable structural and functional *** supports common downstream applications,including genome browsers,and generates extensive details on the filtering process,including distributions that can be visualized to further assess the proposed gene *** is freely available and implemented in Perl with support from BioPerl libraries at https://***/PlantGenomicsLab/gFACs.

关键词： Genome annotation Bioinformatics Protein annotation Gene prediction Alignment

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Development of spinal deformities in the tight-skin mouse

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Bone Research 2017年第1期5卷 63-71页

作者： Bing Li jill PG Urban Jing Yu Department of Orthopedics Tianjin Hospital Department of Physiology Anatomy and GeneticsUniversity of Oxford

Tight-skin （TSK） mice are commonly used as an animal model to study the pathogenesis of Marfan syndrome （MFS）, but little is known of their skeletal phenotype and in particular of the development of the spinal deformities, common in MFS. Here we examined growth of the axial skeletons of TSK and wild-type（B6） mice during their period of rapid growth. The whole bodies of mice, 4-12 weeks of age, were scanned after sacrifice, by micro-computed tomography （microCT）. We reconstructed three-dimensional models of the spine and ribs, and measured vertebral body heights and rib lengths using the Mac-based image-processing software ＂OsiriX＂. Although the TSK mice were smaller than the B6 mice at 4 weeks, they experienced an early growth spurt and by 8 weeks the height, but not the width, of the vertebral body was significantly greater in the TSK mice than the B6 mice. Measurement of the angles of scoliotic and kyphotic curves postmortem in the mice was problematic, hence we measured changes that develop in skeletal elements in these disorders. As a marker of kyphosis, we measured anterior wedging of the vertebral bodies; as a marker for scoliosis we measured asymmetries in rib length. We found, unlike in the B6 mice where the pattern was diffuse, wedging in TSK mice was directly related to spinal level and peaked steeply at the thoracolumbar junction. There was also significant asymmetry in length of the ribs in the TSK mice, but not in the B6 mice. The TSK mice thus appear to exhibit spinal deformities seen in MFS and could be a useful model for gaining understanding of the mechanisms of development of scoliosis and kyphosis in this disorder.

关键词： TSK Development of spinal deformities in the tight-skin mouse Figure

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Understory vascular plant community assembly in relation to time-since-fire and environmental variables in a Chinese boreal forest

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Journal of Mountain Science 2017年第7期14卷 1317-1328页

作者： LIU Bo YANG Jian jill F.JOHNSTONE Key Laboratory of Forest Ecology and Management Institute of Applied Ecology Chinese Academy of Sciences University of Chinese Academy of Sciences Department of Forestry TP Cooper Building University of Kentucky Department of Biology University of Saskatchewan

Understanding the response of understory vegetation to fire disturbance is vital to biodiversity conservation and management of boreal forests. We surveyed understory vascular plant richness and composition, and measured related environmental variables along a toposequence within three successional stages, initial （3 years post-fire）, early （13 years post-fire） and late （〉1oo years post-fire） successional stages. Using permutation multivariate ANOVA and nonmetric multidimensional scaling, we analyzed how understory species richness and composition change as time-since-fire proceeds, and their correlative relationships with environmental variables. Species richness and composition showed significant differences among the three successional stages. Understory species richness and abundance were significantly associated with time-since-fire, topographic position, elevation and organic layer depth. Among these variables, time-since-fire had the strongest effect and topographic position was the second major factor on affecting understorycommunity assembly. In overwhelmed the effects addition, time-since-fire of soil pH in the initial successional stage and gravimetric soil moisture in early and late successional stages on understory species composition

关键词： Understory richness Composition Firedisturbance Succession Great Xing'an Mountains Ordination

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Facile Synthesis of FeS2 Quantum-Dots/Functionalized Graphene-Sheet Composites as Advanced Anode Material for Sodium-ion Batteries

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Chinese Journal of Chemistry 2017年第1期35卷 73-78页

作者： Yiben Shao jill Yue Shuo Sun Hui Xia School of Materials Science and Engineering Nanjing University of Science and Technology Nanjing Jiangsu 210094 China Herbert Gleiter Institute ofNanoscience Nanjing University of Science and Technology Nanjing Jiangsu 210094 China

FeS2 quantum-dots/functionalized graphene-sheet （QDs/FGS） composites are prepared by a facile and scalable method. The FeS2 QDs/FGS composites can be used as anode materials for sodium-ion batteries. The FeS2 QDs/FGS composites can achieve large specific discharge and charge capacities of 742 and 683 mAh·g-1 （based on the total mass of the FeS2 QDs/FGS composites） at the current density of 0.5 A·g-1 in the first cycle, respectively, and retain a reversible charge capacity of 552 mAh·g-1 after 100 cycles. The FeS2 QDs/FGS composites can display high specific capacities of 452 and 315 mAh·g-1 at the high current densities of 2 and 5 A·g-1. These results indicate that the FeS2 QDs/FGS composites have good cycle performance and high rate capability, making them promising candidates as anode material for sodium-ion batteries.

关键词： quantum dots FeS2 functionalized graphene-sheet sodium-ion batteries

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